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Faculty and Research

Jeff Moore, PhD

Associate Professor
Director, Cell Biology, Stem Cells and Development Program
Contact Jeff Moore

Caitlin Moloney

Program Administrator
Cell Biology, Stem Cells and Development
Contact Caitlin

We are an interactive group, with a strong emphasis on collaboration and cooperation. Faculty are deeply engaged in student mentoring; they provide both oversight and support as students work toward their doctoral degree. The intent is to train students as future academic peers, and provide a rigorous and engaging intellectual environment for all program members.

Members of the CSD Program currently include:

  • 33 full time PhD students
  • 60 faculty from 15 academic and clinical departments


Faculty participating in the CSD Program hail from 8 diverse biomedical departments, yet are intellectually linked through our graduate program by their common research interests. Moreover, our 60 faculty members and their labs further align themselves with, but are not restricted to, 1 or more of 6 research sub-areas under the umbrella of our CSD Program:

  • Anesthesiology
  • Biochemistry and Molecular Genetics
  • Cardiovascular and Pulmonary
  • Cell & Developmental Biology
  • Craniofacial Biology
  • Dermatology
  • Endocrinology
  • Gastroenterology
  • Immunology
  • Medical Oncology
  • Obstetrics and Gynecology
  • Orthopedics
  • Otolaryngology
  • Pathology
  • Pediatrics

Faculty List

Cell Biology
Stem Cells
Development and repair of the vertebrate nervous systemNoYesNoYes
Molecular, genetic and developmental mechanisms involved in the patterning of the early spinal cord (neural plate) during vertebrate embryogenesisNoNoNo
Developmental neurobiology; patterning and formation of sensory organsNoYesYesYes
Mechanisms underlying developmental signaling in mice and in fruit flies and genetic modeling of human disordersNoYesNo
Cellular heterogeneity and electrical synapse plasticity in pancreatic islet function, and dysfunction in diabetes, ageing and therapeutic treatmentsYesNoNo
Clinical interventions combined with mechanistic investigations by using primary human cell culture modelsNoYesNo
Development of the mammalian retinaNoYesNoYes
Functional regulation of ion channels in plasma membranes and Golgi membranes using electrophysiology and molecular biologyYesNoNo
Signaling pathways regulating craniofacial and cardiovascular developmentNoYesNoNo
Programmed DNA elimination, novel RNAs, and RNA metabolismYesNoNoNo
Cancer Evolution and Cancer Signaling PathwaysYesNoNoYes
Extracellular Signals in Intestinal Stem Cell NicheNoNoYes
The role of circadian rhythm proteins in cellular adaptation to hypoxia and ischemiaYesNoNo
Molecular and cellular mechanisms of early embryonic development in C. elegans using genetic and biochemical approachesYesYesNo
Receptor tyrosine kinase signaling in mammalian craniofacial developmentYesYesNoYes
Development and organization of taste and smellNoYesNo
Neural stem cell fate-specification, neurogenesis, cell migration and circuit formation in the developing CNSNoYesNoYes
Investigating novel targets and therapeutic strategies in the treatment of pediatric high-grade glioma (HGG), including diffuse intrinsic pontine glioma (DIPG)NoNoNo
Cell determination, developmental patterning and hedgehog signaling in drosophilaYesYesNo
Oligodendrocytes and their Precursors in the Adult Central Nervous SystemNoNoNoYes
mRNA surveillance in health and diseaseYesNoNoYes
Seek to understand how the lung repairs itself, and to create new approaches to repairing and regenerating lung tissueNoYesYesYes
Molecular, cellular and genetic basis of neurodevelopmental mechanisms involved in risk for schizophrenia and other psychiatric disordersYesYesNo
Molecular mechanisms and targeted therapies for squamous cell carcinomasYesNoNo
Mechanisms of lymphatic mediated metastasis of breast cancer.NoYesNo
Oligodendrocyte development and diseaseYesYesNo
Define how pulmonary mesenchymal vascular progenitor cells (MVPC) regulate microvascular function and adaptive angiogenesis underlying the pathogenesis of chronic lung diseases (CLDs), including emphysema, fibrosis and TSC/LAM.YesNoYesNo
Mammary gland development and functionYesNoNo
Mechanisms of assembly and inheritance of dynamic macromolecular structures: Higher-order septin assemblies in budding yeastYesNoNoYes
Molecular regulation of the microtubule network in cell division and diseaseYesNoNo
How cells acquire their fates during development and how these processes go wrong in congenital disease.NoNoNoNo
Skeletal development and variabilityNoYesNoYes
Genetic mechanisms of limb, lung, and neural developmentNoNoNo
The therapeutic potential of bone marrow stem cells and induced pluripotent stem cells.NoNoNo
Cell biology of the cytoskeleton: Centriole assembly and functionYesNoNoYes
How inflammation reprograms hematopoietic stem cell (HSC) fate choicesYesYesYes
Molecular mechanisms regulating the establishment and maintenance of cellular polarity in epithelial cells and neuronsYesYesNoYes
The role of MYC in the regulation of hematopoietic stem cell self-renewal, proliferation, differentiation and survivalNoNoYes
The Genetic Basis of Obesity and Neuronal Control of Energy Balance in Drosophila melanogasterYesYesNoYes
Olfactory signal transduction and olfactory sensory coding using electrophysiological, morphological and molecular techniquesYesYesNo
Role of protein kinase C delta signaling in apoptosis and cancerYesNoNo
Post-transcriptional gene regulation; mRNA decay; translationYesNoNo
Skin development and diseaseNoYesYes
Our laboratory is interested in insulin-producing pancreatic beta cells in health and disease.YesNoNoYes
Epigenetic and Transcriptional Control of Zebrafish EmbryogenesisYesYesNoYes
Investigating the genetic and biological determinants of diseases that are influenced by the environmentNoNoNoYes
CNS vascular development and stabilityNoYesNo
Mechanisms governing cardiomyocyte lineage commitment and pathogenesis of cardiomyopathiesYesYesNoYes
Our lab is primarily focused on molecular mechanisms underlying abnormal placental blood flow and function.YesYesNo
Deciphering the role of interferon signaling in Down syndrome using a combination of cell-based and in vivo modelsYesYesNoYes
The main focus of our research is to understand the complex transcriptional networks that regulate development, differentiation and function of the pancreasNoYesNo
Gene expression; subcellular RNA localization; localized translation in neurons; high-throughput screening; RNA-seqYesNoNoYes
Mitochondrial dysfunction in intestinal diseaseYesNoNoNo
Pediatric Oncology & Neuro-Oncology with an emphasis on medulloblastoma.YesNoNo
How multiciliated cells adopt their cell fate, build cilia and orient the cilia for directional clearance during normal development, regeneration and human disease.YesNoNo
TGFbeta signaling in cancer and skin developmentYesYesYesYes
Transcriptional regulation of mouse embryonic development and the role of transcription factors in mammary gland development and breast cancerNoYesNo
Osteoarthritis pathogenesis & treatment; Connections between the gut microbiome and skeletal homeostasis & diseaseYesNoYesYes






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