Skip to main content
Sign In


COMIRB Contacts



The Colorado Multiple Institutional Review Board is an administrative body established to protect the rights and welfare of human research subjects recruited to participate in research activities conducted under the auspices of the University of Colorado Denver and its affiliates: Children's Hospital Colorado, Denver Health and Hospital Authority, University of Colorado Hospital, and the VA Eastern Colorado Health Care System.

In the review and conduct of research, actions by COMIRB will be guided by the principles of respect for persons, beneficence, and justice set forth in the Ethical Principles and Guidelines for the Protection of Human Subjects of Research (often referred to as the Belmont Report). Reviews of research will be performed in accordance with the Department of Health and Human Services (HHS) regulations at 45 CFR 46 (also known as the “Common Rule”) and the Food and Drug Administration (FDA) regulations at 21 CFR 50 and 21 CFR 56.

Mission Statement

To protect human research participants' rights and welfare and to facilitate ethical research


  • Provide high-quality, timely, and consistent reviews of human research
  • Provide exceptional customer service
  • Provide effective consultation, training and guidance for researchers


To honor its commitment to the VA Eastern Colorado Health Care System, COMIRB abides by the Department of Veterans Affairs policies for human research protection, including the regulations at 38 CFR 16, and the VHA Handbook 1200.05.

The actions of COMIRB will also conform to all other applicable federal, state, and local laws and regulations.​​​

Partner Programs

Affiliate Sites

COMIRB Documents