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University of Colorado Denver College of Liberal Arts and Sciences

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Faculty & Staff Directory

Aimee Bernard, Ph.D.

Dr. Aimee Bernard

Senior Instructor

Email: Aimee Bernard

Office Location: SI 2071

Phone: (303) 556-6250

Fax: (303) 556-4352

2015 Spring Semester Office Hours:
T   9:30-10:30a
W 11:00a-Noon
No office hours during spring break or finals week

Areas of Expertise:

Immunology, B cell development and signaling​​

Education & Degrees

Ph.D., Immunology & Vaccine Biology, University of Rochchester, 2001

B.A., Biology, Gustavus Adolphus College, 1995


Dr. Bernard has been on the faculty at the University of Colorado Denver since 2007 and is a full-time Senior Instructor in the Department of Integrative Biology. Dr. Bernard teaches a variety of upper-level biology courses, including Immunology, Genetics, Virology, and Molecular Biology. In 2010, she received the award for "Excellence in Teaching" from the University of Colorado Denver, College of Liberal Arts and Sciences and was selected to participate in the 2010 National Academies of Sciences and Howard Hughes Medical Institute Mountain West Summer Institute on Undergraduate Education in Biology. Dr. Bernard is the faculty sponsor for all biology undergraduates that participate in and earn credit for experiential learning through the Biology Internship course, BIOL 3939. In addition to teaching, Dr. Bernard sponsors several students each spring in the annual Research and Creative Activities Symposium (RaCAS) at the University of Colorado Denver and Anschutz Medical Campus and she is a member of the Teaching Effectiveness Committee within the Department of Integrative Biology. Dr. Bernard was also recently inducted as a student-elected Honorary Member to the Golden Key Internationl Society in 2012.

In her free time, she spends time training for marathons, skiing, reading and enjoying her family.

Select Publications​

Desai, S., Loomis, Z., Pugh-Bernard, AE, Schrunk, J., Doyle, MJ, Minic, A., McCoy, E., Sussel, L. 2008. Nkx2.2 regulates cell fate choice in the enteroendocrine cell lineages of the intestine. Developmental Biology 313 (1):58-66.


Wei, C., Anolik, J., Cappione, A., Sheng, B, Pugh-Bernard, A., Brooks, J., Lee, E-H., Milner, E.C.B., Sanz, I. 2006. A new population of cells lacking expression of CD27 represents a major component of the B cell memory compartment in SLE. Journal of Immunology

178 (10);6624-6633.


Pugh-Bernard, A., Cambier, J. 2006. B cell receptor signaling in human systemic lupus erythematosus. Current Opinion in Rheumatology 18:451-455.


Cappione, A.J., Anolik, J.H., Pugh-Bernard, A.E., Bernard, J., Ducher, P., Silverman, G., Sanz, I. 2005. Germinal center exclusion of autoreactive B Cells is defective in human systemic lupus erythematosus. Journal of Clinical Investigation 115:3205-3216.


Anolik, J.H., Bernard, J., Cappione, A., Pugh-Bernard, A.E., Felgar, R.E., Looney, R.J., Sanz, I. 2004. Rituximab improves periperal B Cell abnormalities in human SLE. Arthritis & Rheumatism 50(11):3580-3590.


Prado, C.L.*, Pugh-Bernard, A.E.*. Elghazi, L., Sosa-Pineda, B., Sussel, L. 2004. Ghrelin cells replace insulin-producing β cells in two mouse models of pancreas development. Proceedings of the National Academy of Sciences 101(9):2924-2929.

*authors contributed equally to this work.


Dal Porto, J.M., Gauld, S.B., Merrell, K.T., Mills, D., Pugh-Bernard, A.E., Cambier, J.C. 2004. B Cell Antigen Receptor Signaling 101. Molecular Immunology 41(6-7):599-61.


Pugh-Bernard, A.E., Cappione, A., Anolik, J.H., Sanz, I. 2004. From cold-agglutinin disease to SLE. Lessons in human tolerance and its breakdown. Transfusion Medicine and Hemotherapy 31(2):84-90.


Cippione, A.J., Pugh-Bernard, A.E., Anolik, J.H., Sanz, I. 2004. Lupus IgG VH4.34-encoded antibodies bind to a 220-KDa glycoform of CD45/B220 on the surface of human B lymphocytes. Journal of Immunology 172(7):4298-1070.


Pugh-Bernard, A.E., Silverman, G.J., Ryan, D., Insel, R., Sanz, I. 2001. Regulation of inherently autoreactive VH4.34 B cells in the maintenance of human B cell tolerance. Journal of Clinical Investigation 108():1060-1070.

Courses Taught​

Advanced Topics in Immunology (BIOL 4622/5622)

Advanced Topics in Microbiology: Virology (BIOL 4051/5051)

Biology Internship (BIOL 3939)

General Genetics (BIOL 3832)

Introduction to Immunology (BIOL 3621)

Introduction to Molecular Biology (BIOL 3124)