Mary Beth Makic is focused on nursing-driven interventions that optimize outcomes of critically ill and acutely ill patients. She has been a clinical nurse specialist in critical care for more than 20 years and is recognized as a leader in evidence-based practice, having developed the first group to champion evidence-based practice at the University of Colorado Hospital in 1999 and having co-chaired it ever since. Makic has been successful in supporting bedside nurses as they implement evidence-based practice. Her passion and commitment focus on applying current evidence and research to nursing assessment/intervention and thereby to maximize patient comfort and outcomes. Her areas of research interest and practice improvement encompass a diverse array of nursing-specific interventions, with a vast amount of work in the field of pressure-ulcer prevention/skin-related intervention in the acute-care practice environment. Her current clinical position as Research Nurse Scientist in Critical Care builds on this experience and expertise. She has several active studies and quality-improvement projects in the acute-care nursing-practice environment (e.g., prevention of pressure ulcers among high-risk perioperative patients, sedation management among non-intubated burn-injured patients, effectiveness of chlorhexidine gluconate versus standard bathing in reducing hospital-acquired infections).