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Title

Connecting Gene Expressions with Therapeutics

Project Description

High-throughput genomic technologies enable researchers to ana-lyze tens of thousands of “omic” data points within biological sys-tems. Typically, long lists of interesting candidate genes were gen-erated from these analyses. However, interpreting these gene lists remains a challenge for biomedical researchers. This project will utilize publicly available gene expression profiles deposited in the NCBI GEO, to build connectivity map that links between gene signatures and drugs.  Computational methods will be developed to query, match and rank the connections between gene signatures and drugs. A web resource will be developed to provide users to query this resource.

Area of Study

Hematology and Oncology; Pharmacology and Physiology

Populations

 

Method

Other – please specify

Disease or Symptom

Cancer

Department

Medicine

Mentor Location

12801 E.17th Ave, L18-8116

Mentor Contact Number

303-724-2520

Mentor Email

aikchoon.tan@ucdenver.edu

Website

http://tanlab.ucdenver.edu

Mentor Name

Tan, Aik Choon

Funding Department/Program

Cancer Center

Status

Current

Display on public listing?

Yes

Upload Date

12/21/2015

Attachments

Created at 12/28/2015 11:47 AM by Ross, Randy
Last modified at 11/6/2018 10:38 AM by Zoghby, Caitlin