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Title

Varicella virus latency and Reactivation

Project Description

Our lab varicella pathogenesis and latency and reactivation in an animal model. Studies include the role of cell-mediated immunity in the regulation of varicella latency and reactivation. A bacmid-based approach is used to generate mutant varicella virus to study immune evasion by varicella viruses. State-of-the-art technologies such as multiplex PCR analysis is also used for simultaneous detection of multiple human herpes viruses in biological specimens. Finally, the laboratory uses diagnostic tools to understand neurological complications of zoster including postherpetic neuralgia.

Area of Study

Immunology and Autoimmune Diseases

Populations

 

Method

Animal Models; Cell Biology, Molecular Biology, and Genetics

Disease or Symptom

Immune Related Disease

Department

Neurology

Mentor Location

12700 East 19th Avenue

Mentor Contact Number

3037244324

Mentor Email

ravi.mahalingam@ucdenver.edu

Website

 

Mentor Name

Mahalingam, Ravi

Funding Department/Program

Neurology

Status

Current

Display on public listing?

Yes

Upload Date

 

Attachments

Created at 8/21/2015 7:55 AM by Ross, Randy
Last modified at 8/14/2019 12:56 PM by Zoghby, Caitlin