Dr. Caplan is a rheumatologist and Staff Physician at the University of Colorado Hospital as well as the Denver Veterans Affairs Medical Center. He has a doctoral degree in Health Services Research from the University of Colorado Graduate School.
Dr. Caplan engages in clinically-oriented epidemiologic and health service research within the field of pharmacoepidemiology and autoimmunity/rheumatology.
Areas of interest include retrospective analysis of databases, as well as prospective data collection and analysis.
Dr. Caplan’s has worked with the National Data Bank for Rheumatic Diseases, focusing on the pharmacoepidemiology of steroids in patients with Rheumatoid Arthritis (RA), as well as pulmonary complications of RA and its treatment.
Representative Publications:
1. Elami A, Caplan L, Rudis E. How do you spell 21 mm? Eur J Cardiothorac Surg 1999;16(2):253-254. PMID: 10485433
2. Hron J, Caplan L (Co-first author), Gerth A, Schwartzberg P, Peng S. SH2D1A regulates T-dependent humoral autoimmunity. J Exp Med 2004;200(2):261-266. PMID: 15263031
3. Wolfe F, Caplan L, Michaud K. Treatment for Rheumatoid Arthritis and the Risk of Hospitalization for Pneumonia: Associations with Prednisone, Disease Modifying Antirheumatic Drugs and Anti-Tumor Necrosis Factor Therapy. Arthritis Rheum 2006; 54(2):628-634. PMID: 16447241
4. Wolfe F, Caplan L, Michaud K. Rheumatoid Arthritis Treatment and the Risk of Severe Interstitial Lung Disease. Scand J Rheum 2007; 36(3):172-178. PMID: 17657669
5. Caplan L, Wolfe F, Russell, Michaud K. Corticosteroid use in rheumatoid arthritis: Prevalence, predictors, correlates and outcomes. J Rheumatol 2007; 34:696-705. PMID: 17299838
6. Caplan L, Hoffecker L, Prochazka AV. Ethics in the rheumatology literature: a systematic review. Arthritis Rheum [Arthritis Care and Research] 2008;59(6):816-821. PMID: 18512718
7. Caplan L, Saag KG. Glucocorticoids and the Risk of Osteoporosis. Expert Opin Drug Saf 2009; 8 (1):33-47. PMID: 19236216
8. McDonald JR, Zeringue AL, Caplan L, Ranganathan P, Xian H, Burroughs TE, Fraser VJ, Cunningham F, Eisen SA. Herpes zoster risk and risk factors in a national cohort of veterans with rheumatoid arthritis. Clin Infect Dis. 2009 May 15;48(10):1364-71. PMID: 19368499
9. Scherrer JF, Virgo KS, Zeringue A, Bucholz KK, Jacob T, Johnson RG, True WR, Carney RM, Freedland KE, Xian H, Caplan L, McDonald J, Eisen SA. Depression increases risk of incident myocardial infarction among Veterans Administration patients with rheumatoid arthritis. Gen Hosp Psychiatry. 2009 Jul-Aug;31(4):353-9. PMID: 19555796
10. Michaud K, Mikuls TR, Call SE, Reimold AM, Hooker R, Kerr GS, Richards JS, Caplan L, Cannon GW. Poor to modest agreement between rheumatoid arthritis response measures in clinical practice. Clin Exp Rheumatol 2009 Jul-Aug;27(4):633-40. PMID: 19772796
11. Richards JS, Peng J, Mikuls TR, Amdur RL, Hooker RS, Michaud K, Reimold AM, Cannon GW, Caplan L, Johnson D, Hines AE, Kerr GS. Dual energy x-ray absorptiometry and evaluation of the Osteoporosis Self Assessment Tool in men with rheumatoid arthritis. J Clin Densitom 2009;12(4):434-440. PMID: 19775920
12. Caplan L, Pittman CB, Zeringue AL, Scherrer JF, Wehmeier KR, Cunningham FE, Eisen SA, McDonald JR. Musculoskeletal pain among patients on bisphosphonates: a possible adverse drug reaction. Mayo Clin Proc. 2010 Apr;85(4):341-8. PMID: 20231335
13. Hirsh JM, Boyle DJ, Collier DH, Oxenfeld A, Caplan L. Health literacy predicts the discrepancy between patient and provider global assessments of rheumatoid arthritis activity at a public urban rheumatology clinic. J Rheumatol. 2010 May;37(5):961-6. PMID: 20231210
14. Miriovsky BJ, Michaud K, Thiele GM, O’Dell JR, Cannon GW, Kerr GS, Richards JS, Johnson D, Caplan L, Reimold AM, Hooker RS, Mikuls TR. Anti-CCP antibody and rheumatoid factor concentrations predict greater disease activity in men with rheumatoid arthritis. Ann Rheum Dis. 2010 Jul;69(7):1292-7. PMID: 20439294
15. Caplan L, Hines AE, Williams E, Prochazka AV, Saag KG, Cunningham F, Hutt E. An observational study of glucocorticoid induced osteoporosis prophylaxis in a national cohort of
male veterans with rheumatoid arthritis. Osteoporosis International 2010 (Accepted). PMID: 20358362
16. Lane MA, McDonald JR, Zeringue AL, Caplan L, Curtis JR, Ranganathan P, Eisen SA. Hospitalization for infection in patients with rheumatoid arthritis. Medicine 2010 (Accepted).
17. Davis LA, Larson MM, Caplan L. Observational study to determine predictors of rheumatology clinic visit provider contact time. Arthritis Care and Research 2010 (Accepted). PMID: 20583104
18. Mikuls TR, Fay BT, Michaud K, Sayles H, Thiele GM, Caplan L, Johnson D, Richards JS, Kerr GS, Cannon GW, Reimold A. Mortality in U.S. veteran men with rheumatoid arthritis: results from the VARA registry. Rheumatology 2010 (Accepted)
19. Kerr GS, Sabahi I, Richards JS, Caplan L, Cannon GW, Reimold A, Thiele GM, Johnson D, Mikuls TR. Prevalence of vitamin D insufficiency/deficiency in rheumatoid arthritis and associations with disease severity and activity. J Rheumatol. 2010 (Accepted).
20. Grossman JM, Gordon R, Ranganath VK, Deal C, Caplan L, Chen W, Curtis JR, Furst DE, McMahon M, Patkar NM, Volkmann E, Saag KG. American College of Rheumatology 2010 recommendations for the prevention and treatment of glucocorticoid-induced osteoporosis. Arthritis Care and Research 2010 (Accepted).