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Susan Boackle MD

Associate Professor of Medicine and Immunology


​Dr. Susan Boackle is Associate Professor of Medicine and Immunology at the University of Colorado School of Medicine. 

Dr. Susan Boackle’s clinical and research interests focus on systemic lupus erythematosus.  Lupus is an autoimmune disease that is marked by episodes of increased disease activity called flares, during which antibodies to double stranded (ds) DNA go up, complement levels go down, and inflammation occurs in the body, causing cumulative damage to vital organs over time.   

These antibodies to dsDNA are first made several years before a person is diagnosed with lupus, at a time when they have no other symptoms.

Dr. Boackle’s laboratory has found that a specific change in the sequence of a complement receptor gene expressed in B cells reduces the chances that a person will get lupus. Interestingly, this change specifically appears to protect them from making antibodies to dsDNA.

The goal of Dr. Boackle’s research is to develop a new treatment for lupus that mimics the effects of this sequence change. If this treatment is effective, it will stop the production of anti-dsDNA antibodies.  As a result, it will decrease the likelihood that a person with lupus will have another flare of their lupus and reduce the chances that a person who is at risk for lupus will develop the disease.  It also holds promise for other autoimmune diseases in which B cells play a role in disease pathogenesis, such as rheumatoid arthritis, multiple sclerosis, and diabetes mellitus.​

If you are interested in learning more, please contact Dr. Boackle at susan.boackle@ucdenver.edu.

EDUCATION:                

1981-1985         B.S.  Molecular Biology, Vanderbilt University, Nashville, Tennessee 

1985-1989         M.D.  University of Alabama School of Medicine, Birmingham, Alabama

 POSTGRADUATE TRAINING:

1989-1990        Intern in Internal Medicine, Department of Medicine, University of Texas Southwestern Medical Center, Dallas, Texas

1990-1992        Resident in Internal Medicine, Department of Medicine, University of Texas Southwestern Medical Center, Dallas, Texas

1992-1995        Clinical Fellowship in Rheumatology, Department of Medicine, University of ​Texas Southwestern Medical Center, Dallas, Texas.

1992-1996        Research Fellow, Laboratory of David R. Karp, M.D., Ph.D., Rheumatology, Department of Medicine, University of Texas-Southwestern Medical Center, Dallas, Texas.​

​ APPOINTMENTS:

1995-1996       Assistant Instructor of Internal Medicine, Rheumatic Diseases Division,         Department of Medicine, University of Texas Southwestern Medical Center, Dallas, Texas. 

1996-2001       Instructor of Medicine, Division of Rheumatology, Department of Medicine, University of Colorado Health Sciences Center, Denver, Colorado. 

2001-2007       Assistant Professor, Division of Rheumatology, Department of Medicine,  University of Colorado Health Sciences Center, Denver, Colorado.      

2002-2007       Assistant Professor, Department of Immunology, University of Colorado Health Sciences Center, Denver, Colorado.

2007-2014       Associate Professor, Departments of Medicine and Immunology, University of Colorado Denver School of Medicine, Aurora, Colorado

2007-2015       Associate Division Head – Research Programs, Division of Rheumatology, Department of Medicine, University of Colorado Denver, Aurora, Colorado

2014-           Associate Professor, Departments of Medicine and Immunology, University of Colorado School of Medicine, Aurora, Colorado

2014-           Faculty Appointment, Denver Veteran Affairs Medical Center, Denver, Colorado​

HONORS: 

1985                 Magna Cum Laude Graduate, Vanderbilt University 

2002                 Harmon Arthritis Research Award, Arthritis Foundation, Rocky Mountain Chapter 

2002                 AAI Junior Faculty Travel Award 

2008                 Fellow, American College of Physicians 

2008                 Charley J. Smyth Endowed Chair for Rheumatology Research, University of                                      Colorado School of Medicine 

2009                 Member, Western Society for Clinical Investigation (WSCI) 

2010                 Edmund L. Dubois, M.D. Memorial Lectureship, American College of Rheumatology                          Annual Meeting, Atlanta, Georgia 

2011                 Women in Medicine and Science Professional Leadership Award