Richard J. Martin, M.D.
Professor of Medicine
University of Colorado Denver
Education & Training
University of Michigan, Ann Arbor
1967 B.S. Zoology
Good Samaritan Hospital, Phoenix, AZ
1971-1972 Intern Internal Medicine
Tulane University, New Orleans, LA
1974-1976 Resident Internal Medicine
University of Oklahoma, Oklahoma City
1976-1978 Fellow Pulmonary
Assistant Professor of Medicine, Pulmonary Disease Section, Univ. of Oklahoma Health Sciences Center
Director, Pulmonary Function Laboratory, Veterans’ Administration Medical Center
Assistant Professor of Medicine, Pulmonary Disease Section,Univ. of Colorado Health Sciences Center
Director, Adult Special Care UnitDirector, Sleep Disorders Program, National Jewish Medical and Research Center
Head, Bronchoscopy ServiceUniversity of Colorado Denver
Associate Professor of Medicine, Pulmonary Disease Section, University of Colorado Denver
Professor of Medicine
Head, Division of Pulmonary Medicine, National Jewish Medical and Research Center
Vice Chair, Department of MedicineNational Jewish Medical and Research Center
SELECTED REFERENCES SINCE 1995 (Total Publications 198)
Martin RJ, Wanger JS, Irvin CG, Bartelson BB, Cherniack RM, ACRN. Methacholine challenge testing: safety of low starting FEV1. Chest 112:53-56; 1997.
Wenzel SE, Szefler SJ, Leung DYM, Sloan SI, Rex MD, Martin RJ. Bronchoscopic evaluation of severe asthma: persistent inflammation associated with high dose glucocorticoids. Am J Respir Crit Care Med, 156:737-743, 1997.
Minshall EM, Leung DYM, Martin RJ, Song YL, Cameron L, Ernst P, Hamid Q. Eosinophil-associated TGF-b1 mRNA expression and airways fibrosis in bronchial asthma. Am J Respir Cell Mol Biol 17:326-333, 1997.
Fish JE, Peters SP, Chambers CV, Martin RJ, ACRN. An evaluation of colchicine as an alternative to inhaled corticosteroids in moderate asthma. Am J Respir Crit Care Med 156:1165-1171, 1997.
Pincus DJ, Humeston TR, Martin RJ. Further studies on the chronotherapy of asthma with inhaled steroids: the effect of dosage timing on drug efficacy. J Allergy Clin Immunol 100:771-774, 1997.
Kraft M, Cassell GH, Henson JE, Watson H, Williamson J, Marmion BP, Gaydos CA, Martin RJ. Detection of mycoplasma pneumoniae in the airways of adults with chronic asthma. Am J Respir Crit Care Med 158:998-1001, 1998.
Martin RJ, Banks-Schlegel S. Chronobiology of asthma. Am J Respir Crit Care Med 158:1002-1007, 1998.
Kraft M, Rennard SI, Striz I, Bettinger CM, Rex M, Martin RJ. Expression of epithelial markers in nocturnal asthma. J Allergy Clin Immunol 102:376-381, 1998.
Vianna EO, Westcott J, Martin RJ. The effects of upper respiratory infection on T-cell proliferation and steroid sensitivity of asthmatics. J Allergy Clin Immunol 102:592-597, 1998.
Chu HW, Halliday JL, Martin RJ, Leung DYM, Wenzel SE. Collagen deposition in large airways may not differ-entiated severe asthma from milder forms of the disease. Am J Respir Crit Care Med 158:1936-1944, 1998.
Kraft M, Martin RJ, Wilson S, Djukanovic R, Holgate ST. Lymphocyte and eosinophil influx into alveolar tissue in nocturnal asthma. Am J Respir Crit Care Med 159:228-234, 1999.
Kraft M, Vianna EO, Martin RJ, Leung DYM. Nocturnal asthma is associated with reduced glucocorticoid receptor binding affinity and decreased steroid responsiveness at night. JACI 103:66-71, 1999.
Martin RJ, Pak J, Kunselman SJ, Cherniack RM, ACRN. Assessment of the AirWatchÔ lung function monitoring system. J Allergy Clin Immunol 103:535-536, 1999.
Fost DA, Leung DYM, Martin RJ, Brown EE, Szefler SJ, Spahn JD. Inhibition of methylprednisolone elimination in the presence of clarithromycin therapy. J Allergy Clin Immunol 103:1031-1035, 1999.
Martin RJ, Bartelson BB, Smith P, Hudgel DW, Lewis D, Pohl G, Koker P, Souhrada JF. Effect of ipratropium bromide treatment on oxygen saturation and sleep quality in COPD. Chest 115:1338-1345, 1999.
Irvin CG, Pak J, Martin RJ. Airway-parenchymal uncoupling in nocturnal asthma. Am J Respir Crit Care Med 161:50-56, 2000.
Langmack EL, Martin RJ, Pak J, Kraft M. Serum lidocaine concentrations in asthmatics undergoing research bronchoscopy. Chest 117 (4): 1055-1060, 2000.
Langmack EL, Martin RJ. Successful treatment of adult asthma. Int Med World Report 15 (3):10-11, 2000.
Martin RJ. Pathophysiology of asthma: Inflammatory response in small airways and alveolar area. Asthma and the Small Airways (monograph):1-6, 2000.
Israel E, Drazen JM, Liggett SB, Martin RJ and Asthma Clinical Research Network. The effect of polymorphisms of the 2-adrenergic receptor on the response to regular use of albuterol in asthma. Am J Respir Crit Care Med 162:75-80, 2000.
Chu HW, Kraft M, Krause JE, Rex MD, Martin RJ. Substance P and its receptor neurokinin 1 expression in asthmatic airways. J Allergy Clin Immunol 106:713-722, 2000.
Silkoff PE, Martin D, Pak J, Westcott JY, Martin RJ. Exhaled nitric oxide correlated with induced sputum findings in COPD. Chest 119:1049-1055, 2001.
Vanden Burgt JA, Busse WW, Martin RJ, Szefler SJ, Donnell D. Efficacy and safety overview of a new inhaled corticosteroid, QVAR (hydrofluoroalkane-beclomethasone extrafine inhalation aerosol), in asthma. J Allergy Clin Immunol 106:1209-1226, 2000.
Martin RJ, Kraft M, Chu HW, Berns EA, Cassell GH. A link between chronic asthma and chronic infection. J Allergy Clin Immunol 107:595-601, 2001.
Kraft M, Hamid Q, Chrousos GP, Martin RJ, Leung DY. Decreased steroid responsiveness at night in nocturnal asthma. Is the macrophage responsible? Am J Respir Crit Care Med 163:1219-1225, 2001.
Leone FT, Mauger EA, Peters SP, Chinchilli VM, Fish JE, Boushey HA, Cherniack RM, Drazen JM, Fahy JV, Ford J, Israel E, Lazarus SC, Lemanske RF, Martin RJ, McGeady SJ, Sorkness C, Szefler SJ. The utility of peak flow, symptom scores, and -agonist use as outcome measures in asthma clinical research. Chest 119:1027-1033, 2001.
Martin RJ, Chu HW, Honour JM, Harbeck RJ. Airway inflammation and bronchial hyperresponsiveness after Mycoplasma pneumoniae infection in a murine model. Am J Respir Cell Mol Biol 24:577-582, 2001.
Reeves. (2001). New insights into the regulation of vascular tone during cirrhosis. In Preparation.