Dr. Draznin is a Past Chairman of the Professional Section of the American Diabetes Association. He completed his fellowship training in Endocrinology at the University of Colorado in 1980, where he is currently a Professor of Medicine. His basic research focuses on the mechanisms of insulin action. These studies involve mechanisms that regulate glucose uptake, phosphorylation, and de-phosphorylation of the insulin receptor, the glucose transporter, and intracellular substrates of insulin action. These studies involve the biochemistry and physiology of second messenger systems, particularly the Ras oncogene, MAP and PI 3 kinases as they relate to the regulation of the mitogenic and metabolic action of insulin. In broader terms, these studies are designed to unravel the mechanism of post-receptor abnormalities seen in patients with diabetes mellitus, obesity, and insulin resistance, as well as mechanisms of hypertension and atherosclerosis in diabetes mellitus. Dr. Draznin's interests involve mechanisms, pathogenesis, and development of insulin resistance on both clinical and molecular levels. He is also addressing the questions of the mechanism of accelerated atherosclerosis in the presence of insulin resistance.