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University of Colorado Department of Biochemistry and Molecular Genetics

Biochemistry and Molecular Genetics
 

RNA Biology


​​Modern biology has been revolutionized by the discovery that many processes of fundamental importance are regulated by RNA molecules. We continue to realize the potential of RNA regulatory mechanisms, illuminating biology and advancing medicine through development of new RNA therapeutics. Major knowledge gaps remain in the basic, diagnostic and therapeutic areas of RNA Bioscience, and much remains to be discovered about mechanisms of RNA regulation and their impact on biology and disease.

The mission of the RNA Bioscience Initiative is to create and expand a vibrant center of discovery and innovation in RNA research, diagnostics and therapy. Our goal is to provide a fluid pipeline from basic to clinical RNA research at the Anschutz Medical Campus.

Learn more about the RNA Bioscience Initiative​.


Faculty



Francisco Asturias​

David Bentley, PhD
Messenger RNA Production by RNA polymerase II
​​​
Richard Davis, PhD
Programmed DNA elimination, novel RNAs, ​and RNA metabolism


Genomics of gene regulation

Aaron Johnson, PhD
Mechanisms of chromatin-mediated gene silencing

Jeffrey Kieft, PhD
Protein Translation and RNA structure

Rui Zhao, PhD

Molecular mechanism of pre-mRNA splicing; drug design targeting transcriptional complex in breast cancer