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Welcome to the Kieft Lab at HHMI and the University of Colorado, Denver. Our research focuses on understanding the structure and function of the most versatile of all biological macromolecules: RNA. Our main focus is to understand RNAs produced and used by viruses to take over an infected cell. We are motivated by two premises: (1) infectious diseases (such as viruses) are still the largest threat to human health worldwide, and (2) by studying how viruses take over the cell’s machinery, we learn a tremendous amount about fundamental processes within the cell itself.
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