Casas-Selves, M., and DeGregori, J. (2011). How cancer shapes evolution, and how evolution shapes cancer. Evolution: Education and Outreach, 4:624–634. Publication PDF
Aging-Associated Changes in Hematopoiesis and Leukemogenesis: What's the Connection?
Henry CJ, Marusyk A, Degregori
J.Aging (Albany NY). 2011 Jun;3(6):643-56. Publication PDF
Evolved tumor suppression: why are we so good at not getting cancer?
DeGregori
J. Cancer Res. 2011 Jun 1;71(11):3739-44. Epub 2011 May 24.
A new role for E2F1 in DNA repair: All for the greater good.
Degregori J.
Cell Cycle. 2011 Jun 1;10(11):1719-8. Epub 2011 Jun 1.
Relative fitness of hematopoietic progenitors influences leukemia progression.
Porter CC, Baturin D, Choudhary R, DeGregori.
J. Leukemia. 2011 May;25(5):891-5. Epub 2011 Feb 18. No abstract available
Declining lymphoid progenitor fitness promotes aging-associated leukemogenesis.
Henry CJ, Marusyk A, Zaberezhnyy V, Adane B, Degregori J.
Proc Natl Acad Sci U S A. 2010 Nov 22. [Epub ahead of print] Publication PDF
Ionizing radiation and hematopoietic malignancies: altering the adaptive landscape.
Fleenor CJ, Marusyk A, DeGregori J.
Cell Cycle. 2010 Aug 1;9(15):3005-11. Epub 2010 Aug 7. Publication PDF
Mutation-specific control of BCR-ABL T315I positive leukemia with a recombinant yeast-based therapeutic vaccine in a murine model.
Bui MR, Hodson V, King T, Leopold D, Dai S, Fiolkoski V, Oakes S, Duke R, Apelian D, Franzusoff A, DeGregori J.
Vaccine. 2010 Aug 23;28(37):6028-35. Epub 2010 Jul 7.
Wnt/Ca2+/NFAT signaling maintains survival of Ph+ leukemia cells upon inhibition of Bcr-Abl.
Gregory MA, Phang TL, Neviani P, Alvarez-Calderon F, Eide CA, O'Hare T, Zaberezhnyy V, Williams RT, Druker BJ, Perrotti D, Degregori J.
Cancer Cell. 2010 Jul 13;18(1):74-87. Publication PDF
Irradiation selects for p53-deficient hematopoietic progenitors.
Marusyk A, Porter CC, Zaberezhnyy V, DeGregori J.
PLoS Biol. 2010 Mar 2;8(3):e1000324. Publication PDF
Irradiation alters selection for oncogenic mutations in hematopoietic progenitors.
Marusyk A, Casás-Selves M, Henry CJ, Zaberezhnyy V, Klawitter J, Christians U, DeGregori J.
Cancer Res. 2009 Sep 15;69(18):7262-9. Epub 2009 Sep 8.
Interfering RNA-mediated purine analog resistance for in vitro and in vivo cell selection.
Porter CC, DeGregori J.
Blood. 2008 Dec 1;112(12):4466-74. Epub 2008 Jun 27.
Declining cellular fitness with age promotes cancer initiation by selecting for adaptive oncogenic mutations.
Marusyk A, DeGregori J.
Biochim Biophys Acta. 2008 Jan;1785(1):1-11. Epub 2007 Oct 12. Review.
Replicational stress selects for p53 mutation.
Marusyk A, DeGregori J.
Cell Cycle. 2007 Sep 1;6(17):2148-51. Epub 2007 Jul 10.
p53 mediates senescence-like arrest induced by chronic replicational stress.
Marusyk A, Wheeler LJ, Mathews CK, DeGregori J.
Mol Cell Biol. 2007 Aug;27(15):5336-51. Epub 2007 May 21.
Impaired DNA replication within progenitor cell pools promotes leukemogenesis.
Bilousova G, Marusyk A, Porter CC, Cardiff RD, DeGregori J.
PLoS Biol. 2005 Dec;3(12):e401. Epub 2005 Nov 15.
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