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You have reached the Web site for the Department of Pathology at the University of Colorado Denver.

Colorado Genetics Labs
 

Fluorescence in situ Hybridization (FISH)


Fluorescence in situ hybridization (FISH) uses DNA probes specific for particular areas of the genome. It can detect losses and, in some cases, duplication of DNA at a locus.

 

FISH is performed to:

 
    • Enumerate chromosomes
    • Detect partial monosomy and triploidy
    • Diagnose specific microdeletion and microduplication syndromes
    • Detect acquired abnormalities for diagnostic/prognostic indications in certain types of cancer
 

 
FISH Testing at CGL

 

FISH for microdeletion/microduplication syndromes
FISH for gender determination
FISH for chromosome abnormalities common in pregnancy loss​
FISH for chromosome abnormalities in cancer
FISH for chimerism studies in bone marrow transplant patients