Fluorescence in situ hybridization (FISH) uses DNA probes specific for particular areas of the genome. It can detect losses and, in some cases, duplication of DNA at a locus.
FISH is performed to:
- Enumerate chromosomes
- Detect partial monosomy and triploidy
- Diagnose specific microdeletion and microduplication syndromes
- Detect acquired abnormalities for diagnostic/prognostic indications in certain types of cancer
FISH Testing at CGL