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Steven M. Anderson, PhD​

Professor, Vice Chair for Research​ and James C. Todd Professor of Experimental Pathology



  • PhD, Viral Oncology, Rockefeller University, New Y​ork (1981)​

Postdoctoral Education:

  • Postdoctoral Fellow, Laboratory of Tumor Virus Genetics,

    National Cancer Institute, Bethesda, MD (1981-82) 

Research Activities:

Recent Publications (2002 to date):

Journal Articles in Pub Med ( 

 Previous Selected Publications:

1. M.C. Neville, S.M. Anderson, J.L. McManaman, T. M. Badger, M. Bunik, N. Contractor, T. Crume, D. Dabelea, S.M. Donovan, N. Forman, D.N. Frank, J.E. Friedman, J.B. German, A. Goldman, D. Hadsell, M. Hambidge, K. Hinde, N.D. Horseman, R.C. Hovey, E. Janoff, N. Krebs, C.B. Lebrilla, D.G. Lemay, P.S. MacLean, P. Meier, A. Morrow, J. Neu, L.A. Nommsen-Rivers, M. Rijnkels, V. Seewaldt, B.D. Shur, J. VanHouten, P. Williamson, 2012. “Lactation and Neonatal Nutrition: Defining and Refining the Critical Questions,” J. Mammary Gland Biology and Neoplasia 17 (2): 167-188.  PMID 22752723.

2. Rudolph, M.C., N.K. Maluf, E.A. Wellberg, C.A. Johnson, R.C. Murphy, and S.M. Anderson, 2012.  “Mammalian fatty acid synthase activity from crude lysates tracing (13)C-labelled substrates using gas chromatography-mass spectrometry.” Anal. Biochem. 428 (15): 158-166.  PMID 22728958.

3. E.D. Giles, E.A. Wellberg, D.P. Astling, S.M. Anderson, A.D. Thor, S. Jindal, A.C. Tan, P.S. Schedin, and P.S. MacLean, 2012. “Obesity and overfeeding affecting both tumor and systemic metabolism activates the progesterone receptor to contribute to postmenopausal breast cancer.” Cancer Research 72 (24): 6490-6501.  PMID 23222299.

4. R.O. Pereira, A.R. Wende, C. Olsen, J. Soto, T. Rawlings, Y. Zhu, S.M. Anderson, and  E.D. Abel, 2013. “Inducible Overexpression of GLUT1 Prevents Mitochondrial Dysfunction and Attenuates Structural Remodeling in Pressure Overload but does not Prevent Left Ventricular Dysfunction.”  J Am Heart Assoc. 2013 Sep 19;2(5):e000301. doi: 10.1161/JAHA.  PMID 24052497

5. M.C. Neville, P. Webb, P. Ramanathan, M. Phistry, C. Pecorini, J. Monks, S.M. Anderson, P. MacLean, 2013. “The Insulin Receptor Plays an Important Role in Secretory Differentiation in the Mammary Gland.”  American Journal of Physiology-Endocrinology and Metabolism 305 (9): E1103-1114. PMID: 23982156.

6. R. Wahdan-Alaswad, Z. Fan, S.M. Edgerton, B. Liu, X.-S. Deng, S. S. Arnadottir, J. Richer, S.M. Anderson, and A.D. Thor, 2013. “Glucose Promotes Breast Cancer Aggression and Reduces Metformin Efficacy.” Cell Cycle 12(24): 3759-3769.  PMID:24107633.

7. J.W. Schmidt, B.L. Wehde, K. Sakamoto, A.A. Triplett, S.M. Anderson, P.N. Tsichlis, G. Leone and K.-U. Wagner, 2014. “Stat5 regulates the PI3-kinase/Akt1 pathway during mammary gland development and tumorigenesis.” Molecular and Cellular Biology 34 (7): 1363-1377.  PMID 24469394.

8. S.M. Wie, T.S. Adwan, J. DeGregori, S.M. Anderson and M.E. Reyland, 2014.  “Inhibiting tyrosine phosphorylation of PKC protects the salivary gland from radiation damage.” Journal of Biological Chemistry 289 (15): 10900-10908. PMID24569990

9. M.C. Rudolph, E.A. Wellberg, A.S. Lewis, A.L. Merz, N.K. Maluf, N.A. Serkova, and S.M. Anderson, 2014.  Thyroid Hormone Responsive Protein Spot14 enhances catalysis of fatty acid synthase in lactating mammary epithelium.” Journal of Lipid Research 55 (6): 1052-1065.  PMID 24771867.

10. A.N. Macintyre, V.A. Gerriets, A.G. Nichols, R.D. Michalek, M.C. Rudolph, D. Deoliveira D, S.M. Anderson, E.D. Abel, B.J. Chen, L.P. Hale, and J.C. Rathmell, 2014. The glucose transporter Glut1 is selectively essential for CD4 T cell activation and effector function. Cell Metab. 20(1):61-72. PMID: 24930970.

11. R. Wahdan-Alaswad*, D.R. Cochrane*, N.S. Spoelstra, E.N. Howe, S.M. Anderson, A.D. Thor and J.K. Richer, 2014. “Metformin-induced killing of triple negative breast cancer cells is mediated by reduction in fatty acid synthase via miRNA-193b.” Hormones and Cancer, Dec 5(6) 364-389. doi 10.1007/s12672-0188-8. PMID 25213330.

12. E.A. Wellberg, and S.M. Anderson, 2014. FASNating targets of metformin in breast cancer stem-like cells.  Hormones and Cancer, Dec 5(6):358-362. Doi: 1007/s12672-114-0198-6. PMID 25172609.

13. E.A. Wellberg, M.C. Rudolph, A.S. Lewis, N. Padila-Just, P. Jedlicka and S.M. Anderson, 2014.  “Modulation of tumor fatty acids, through overexpression or loss of thyroid hormone responsive protein spot14 is associated with altered growth and metastasis.”  Breast Cancer Research 16:490 (December 4, 2014). PMID: 25472762.

14. R.E. Heinz, M.C. Rudolph, P. Ramanathan, N.S. Spoelstra, K.T. Butterfield, P.G. Webb, B.L. Babbs, H. Gao, S. Chen, M.A. Gordon, S.M. Anderson, M.C. Neville, H. Gu and J. K. Richer, 2016.  “Constitutive expression of microRNA-150 in mammary epithelium suppresses secretory activation and impairs de novo lipogenesis.” Development 143(22):4236-4248.  PMID  27729410.

15. E.A. Wellberg, S. Johnson, K. Terrell, A.S. Lewis, J. Finlay-Schutz, C.A. Sartorius, E. D. Abel, W.J. Muller, and S.M. Anderson, 2016. “The hexose transporter GLUT1 is required for ErbB2-induced mammary tumorigenesis. Breast Cancer Res. 18:131. DOI 10.1186/s13058-016-0795-0 Published online: December 20, 2016

16. L.A. Checkley, M.C. Rudolph, E.A. Wellberg, E.D. Giles, R. Wahdan-Alaswad, J. Houck, S.M. Edgerton, A.D. Thor, P.S. Schedin, S.M. Anderson, and P.S. MacLean, 2017. Metformin Accumulation Correlates with Organic Cation Transporter 2 Protein Expression and Predicts Mammary Tumor Regression in Vivo”.  Cancer Prev. Res.  Feb 2. doi: 10.1158/1940-6207.CAPR-16-0211-T. [Epub ahead of print].  PMID: 28154203

17. E.A. Wellberg, L.A. Checkley, E.D. Giles, S.J. Johnson, R, Oljira, R. Wahdan-Alaswad, R.M. Foright, G. Dooley, S.M. Edgerton, S. Jindal, G.C. Johnson, J.K. Richer, P. Kabos, A.D. Thor, P. Schedin, P.S. MacLean, and S.M. Anderson, 2017.  "The Androgen Receptor supports tumor progression after the loss of ovarian function in a preclinical model of obesity and breast cancer.” Hormones and Cancer 8 (5,6):269-285.​