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Research Opportunities

Orthopaedic Surgery Interest Group

Below you will find research opportunities listed in REDCap that are currently open for students to participate in. Please browse each one of the  divisional tabs and click on the title of the study to submit an inquiry. Each submission will be evaluated and you will be contacted when matched. For more information on research studies, please contact Frank Scott, MD.

​Title of Study ​Principal Investig​ator ​Description
Karen King, PhD. ​Protocol is SOM and VA. I manuscript published and 3 conference presentations.
Dual delivery biomaterial system for the treatment of growth plate injuries ​Karin Payne, PhD.
​To develop a dual delivery biomaterial system that can be implanted into the growth plate injury site where it would first release factors that would promote the recruitment of stem cells to the injured site and then release factors that would encourage the cells to form cartilage tissue rather than bone tissue. This would prevent bony bar formation and the significant bone growth problems associated with growth plate injuries.
​Effect of diabetes on joint inflammation Karen King, PhD.
​Animal samples in progress. Preliminary data anticipated summer, 2013.
Karen King, PhD. ​Animal surgeries and human tissue collection in progress COMIRB 07-0659 listed separately.
Karen King, PhD. This project contains both cell biology and biomechanical research​.

Revitalization of bone allo​graft with induced pluripotent stem cells for improved spine fusion​ ​Karin Payne, PhD. ​The goal​ of this study is to test whether adding stem cells, such as induced pluripotent stem cells, to the bone graft before implantation into a rat model of spine fusion, will lead to more bone formation than if the graft was implanted alone.​
​Title of Study ​Principal Investigator ​Description​
Frank Scott, MD
Frank Scott, MD
Frank Scott, MD
​Retrospective Study of Diabetes, Carpal Tunnel Syndrome, and Trigger Finger Syndrome Frank Scott, MD ​Retrospective study to determine whether there is a significant association between patients with Type II diabetes mellitus who also have carpal tunnel syndrome or trigger finger syndrome.

​Title of Study ​Principal Investigator ​Description
Pre-op Templating for TDR Alignment: Is it Clinically Relevant? Christopher Cain, MD
​The objective of this retrospective study is to evaluate the positioning of disk replacement devices in total disc replacement (TDR) procedures. Using a finite element model (FEM), actual positioning of disk replacement devices will be compared to ideal placement as determined by FEM.  The correlation between actual and ideal placement will then be related to the clinical outcomes to assess the importance of precise device positioning in the TDR procedures.
Evalina Burger, MD ​Hypothesis: The primary hypothesis is cell saver transfusion in spine surgery is associated with coagulation abnormalities or other changes in the body.   Specific Aims: Examine the effect of cell saver transfusion on coagulation during spine surgery.
Prospective study of pedicle screw placement using the O-Arm and Navigated Instrumentation Vikas Patel, MD ​Pedicle screw placement is a commonly used technique for posterior stabilization in the thoracolumbar spine. Misplacement of screws can lead to vascular injury, neurological injury, dural tear, and pedicle fractures that can compromise stable fixation.  Techniques for pedicle screw placement have included the use of anatomic landmarks, laminotomy with palpation of the pedicle, plain radiography, standard fluoroscopic imaging, fluoroscopic image guidance, and computed tomography (CT) image guidance.  Intraoperative fluoroscopy and portable radiographs are routinely used during pedicle screw placement to help guide correct surgical placement of pedicle screw instrumentation. Although these imaging procedures are commonly used to aid pedicle screw placement, their accuracy has been debated.  The O-Arm generates a 3-D image dataset of the spine, similar to CT scanning, that can be downloaded to the Stealth Station. The image data can be viewed on the O-Arm screen in standard transverse, coronal, and sagittal planes or any oblique plane desired.  When combined with the Stealth Station, the image data can be viewed relative to the image guided probes to help to accurately navigate the awl into the pedicle.  Also, if a navigated screwdriver is available, pedicle screws themselves can also be navigated during placement.  After screw placement, the O-Arm can generate a final 3-D data volume to confirm the position of the screws. In less than 30 seconds it can take up to 400 images, which are reconstructed on a flat panel monitor for the surgeon to review before the patient leaves the operating room. These images can be saved and can be recalled anytime.  The O-Arm and Stealth navigation technology replaces the need for fluoroscopy and thus reduces radiation exposure.  While various studies have reported on the use of CT based and Isocentric 3-D fluoroscopy based navigation, there is a paucity of data on the O-Arm and Stealth system using navigated instruments. Thus, the purpose of this proposal is to study the accuracy of pedicle screw placement using O-arm/Stealth as well as the time associated with its intraoperative use.  
​Title of Study​ ​Principal Investigator ​Decription
Eric McCarty, MD
ACL Hybrid graft reconstruction vs HS Autograft. Chart review, questionnaire on REDCap.
CU Sports Medicine Outcomes Registry Eric McCarty, MD​
Proximal Biceps tenotomy versus tenodesis Eric McCarty, MD​
​FELLOWS 2010-2011 STUDY Patients ID'ed though chart review. Research student did a physical exam plus questionnaire administration.
Eric McCarty, MD​ ​Multi-center study based out of Emory Univ. Retrospective chart review.
​Return to Sport After Anterior Shoulder Stabilization 
​Chart review. Questionnaire follow-up study for return to sport for patients who underwent Anterior Shoulder Stabilization with ECM.
The effectiveness of simultaneous intermittent compression and continuous cold therapy on the post-operative shoulder: A randomized controlled trial Eric McCarty, ​MD​
​2 week post RCR surgery. Randomized, x-over, GameReady vs Ice Bags and narcotic demand after shoulder arthroscopy. Assigned to CC/IW or IW/CC. Pt diary, SF-12 at ~ day 10.