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J Mark Petrash, PhD

Professor, Vice Chair of Research, Department of Ophthalmology

The following data are linked to original publications.

  

Publications:

    1. Ruiz FX, Moro A, Gallego O, Ardevol A, Rovira C, Petrash JM, et al. Human and rodent aldo-keto reductases from the AKR1B subfamily and their specificity with retinaldehyde. Chem Biol Interact. 2011.
    2. Li G, Lee CA, Patel M, Petrash JM, Benetz BA, Tang J, Kern TS: Diabetes-induced impairment in contrast sensitivity and visual acuity in mice: contributions of p38, RAGE, and aldose reductase (submitted)
    3. Salabei JK, Li X-P, Petrash JM, Bhatnagar A, Barski OA:Functional expression of novel human and murine AKR1B genes. (in press), 2011
    4. Zablocki GJ, Ruzycki PA, Overbeek MA, Palla S, Reddy GB, Petrash JM: Aldose reductase-mediated induction of epithelial-to-mesenchymal transition (EMT) in lens. (in press), 2011
    5. Srivastava SK, Yadav UCS, Aramati RBM, Saxena A, Tammali R, Ansari N, Bhatnagar A, Petrash JM, Srivastava S, Ramana KV:  Aldose reductase inhibition suppresses oxidative stress-induced inflammatory disorders. (in press), 2011.
    6. Hegde KR, Kowluru RA, Mohr S, Nagaraj RH, Petrash JM: New horizons in research on diabetic complications of the eye: special emphasis on diabetic cataracts and retinopathy. J Ophthal 2010:979040.
    7. Srinivas P, Narahari A, Petrash JM, Swamy MJ, Reddy GB. Importance of eye lens alpha-crystallin heteropolymer with 3:1 alphaA to alphaB ratio: Stability, aggregation, and modifications. IUBMB Life. 2010:693-702.
    8. Huang SP, Palla S, Ruzycki P, Varma A, Harter T, Reddy GB, Petrash JM (2010): Aldo-keto reductases in the eye. J Ophthal 2010:521204, 2010.
    9. Kahook MY, Liu L, Ruzycki P, Mandava N, Carpenter JF, Petrash JM, Ammar DA (2009) High molecular weight adducts in repackaged Bevacizumab. Retina 30:887-892, 2009.
    10. Muthenna P, Suryanarayana P, Gunda SK, Petrash JM, Reddy GB: Inhibition of aldose reductase by dietary antioxidant curcumin: Mechanism of inhibition, specificity and significance. FEBS Lett 583:3637-3642, 2009.
    11. Srivastava S, Vladykovskaya E, Barski OA, Spite M, Kaiserova K, Petrash JM, Chung SS, Hunt G, Dawn B, Bhatnagar A: Aldose Reductase Protects Against Early Atherosclerotic Lesion Formation in Apolipoprotein E-Null Mice. Circ Res 105:793-802, 2009.
    12. Bhagyalaxmi SG, Srivivas PNBS, Barton K, Kumar KR, Vidyvathi M, Petrash JM, Reddy GB, Padma M: A novel mutation (F71L) in A-crystallin associated with age-related cataract results in defective chaperone-like function despite unaltered structure. Biochim Biophys Acta 1792:974-981, 2009.
    13. Shi Y, Barton K, de Maria A, Petrash JM, Shiels A, Bassnett S: The stratified syncytium of the vertebrate lens. J Cell Sci 122:1607-1615, 2009.
    14. Barton KA, Hsu C-D, Petrash JM: Interactions between small heat shock protein alpha crystallin and galectin-related inter-fiber protein (GRIFIN) in the ocular lens. Biochemistry 48:3956-3966, 2009.
    15. Tammali, R, Reddy ABM, Ramana KV, Petrash JM, Srivastava SK: Aldose reductase deficiency in mice prevents axoxymethane-induced colonic preneoplastic aberrant crypt foci formation. Carcinogenesis 30:799-807, 2009.
    16. Saraswat M, Muthenna P, Suryanarayana P, Petrash JM, Reddy GB: Dietary sources of aldose reductase inhibitors: Prospects for alleviating diabetic complications. Asia Pac J Clin Nutr 17,558-565, 2008.
    17. Marchitti SA, Bateman B, Petrash JM, Vasiliou V: Mouse models of the cornea and lens—Understanding ocular disease. In Animal Models of Eye Research (Tsonis PA, ed); Elsevier, 2008.
    18. Reddy GB, Satyanarayana A, Balakrishna N, Ayyagari R, Padma M, Viswanath K, Petrash JM: Erythrocyte aldose reductase activity and sorbitol levels in diabetic retinopathy. Molec Vis 14:593-601, 2008.
    19. Chang Q and Petrash JM: Disruption of aldo-keto reductase genes leads to elevated markers of oxidative stress and inositol auxotrophy in Saccharomyces cerevisiae. Biochem Biophys Acta (Molec Cell Res) 1783:237-245, 2008.
    20. Suryanarayana P, Saraswat M, Petrash JM, Reddy GB: Emblica officinalis and its Enriched Tannoids Delay Streptozotocin-Induced Diabetic Cataract in Rats. Molec Vis 13:1291-1297, 2007.
    21. Spite M, Baba SP, Ahmed Y, Barski O, Nijhawan K, Petrash JM, Bhatnagar A, Srivastava S: Substrate specificity and catalytic efficiency of aldo-keto reductases with phospholipid aldehydes. Biochem J 405:95-105, 2007.
    22. Barton KA, Shui Y-B, Petrash JM, Beebe DC: Comment on: The Stokes-Einstein equation and the physiological effects of vitreous surgery. Acta Ophthal Scand 85:339-340, 2007.
    23. Chang Q, Griest TA, Harter TM, Petrash JM: Phenotypic rescue of aldo-keto reductase null Saccharomyces cerevisiae by human aldose reductase. Biochem Biophys Acta (Molec Cell Res) 1773:321-329, 2007.
    24. Estey T, Wenston PA, Cantore M, Carpenter JF, Petrash JM, Vasiliou V: Mechanisms involved in the protection of UV-induced protein inactivation by the corneal crystallin ALDH3A1. J Biol Chem 282:4382-4392, 2007.
    25. Singh R, White MA, Ramana KV, Petrash JM, Satowich SJ, Bhatnagar A, Srivastava SK: Structure of a glutathione conjugate bound to the active site of aldose reductase. Proteins 64: 101-110, 2006, 2006.
    26. Hsu CD, Kymes S, Petrash JM: A transgenic model for human autosomal dominant cataract. Inv Ophthal Vis Sci 47:2036-2044, 2006.