Dr. Honigman completed his residency in emergency medicine at Denver General Hospital in 1979. He was the Research Director for 1 year and then was the Editor in Chief at Micromedex developing the EMERGINDEX system which was the first emergency medicine textbook using CD technology. He became Section Head of Emergency Medicine at the University of Colorado School of Medicine in the Department of Surgery in 1985 and then became Division Head in 1992. During that time he was a consultant at the Colorado Department of Public Health and Environment where he served as the Medical Director for EMS and Trauma and helped to develop the trauma system for the state. In 2003, he started the Altitude Research Center at the medical school and still functions as its director. He led the effort for the Division of Emergency Medicine to become an academic department in the medical school which occurred in January 2010. He now serves as Interim Chair of that department.
Dr. Honigman has published over 100 papers in the areas of altitude medicine, trauma care and pre-hospital activities. He became a Professor of Emergency Medicine in 2002 and has been instrumental in the development of a strong research and educational program of emergency medicine in the School of Medicine.