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The Department of Dermatology deals with all aspects of the biology and diseases of the skin.

Department of Dermatology

Xiao-Jing Wang, MD, PhD

Dr. Xiao-Jing Wang
Professor and Director
Head and Neck Cancer Research Program
University of Colorado School of Medicine

Xiao-Jing Wang received her M.D. (1984) and Ph.D. (1989) from Beijing Medical University, the most prestigious medical school in China. She came to the United States for her postdoctoral training at the M.D. Anderson Cancer Center in 1990.  In 1992, she joined Dr. Dennis Roop’s laboratory as a Research Associate at Baylor College of Medicine, Houston, TX.  At Baylor, she quickly rose through the ranks to Assistant Professor in 1995, and tenured Associate Professor in 2000 in the Departments of Molecular and Cellular Biology and Dermatology.  In 2003, she was recruited to Oregon Health & Science University (OHSU) as a tenured Full Professor in Otolaryngology, Director of Molecular Biology-Head and Neck Cancer Research Division.  In Aug., 2008, Dr. Wang was recruited to University of Colorado Denver (UCD) as a Director of Head & Neck Cancer Program. She also holds a position as a co-Project Leader of Lung/Head&neck Cancer Program of University of Colorado Cancer Center (UCCC). She currently is John S. Gates Endowed Chair of Cancer Stem Cell Biology.

Dr. Wang has published over 120 research articles in major peer-reviewed journals.  She has been an invited speaker at many prestigious international meetings, e.g., special conferences of the American Association for Cancer Research (2006, 2007), a State-of-the-Art lecture for the Society of Investigative Dermatology (2006), the Annual Meeting of the Japanese Cancer Association (2007), and the Keynote Speaker of Congress of Chinese Dermatology Society (2012).  She served as a member and chair of Scientific Program Committee for the Society of Investigative Dermatology, a committee member for the Dermatology Foundation. She is currently an Advisory Council member for National Institute of Arthritis Muscle and Skin (NIAMS). She won the prestigious William Montagna Award for the 2014 SID annual meeting. This award has been presented annually since 1975 and is intended to recognize investigators who have made outstanding contributions to research in skin biology.

Dr. Wang has a long research career in studying the molecular mechanisms of skin cancer, development and diseases.  Early in her career, she was the recipient of a Career Development Award from the Dermatology Foundation.  During this period, her laboratory made the novel discovery that TGFβ1, a protein which previously was thought to be a growth inhibitor, actually promotes skin tumor metastasis.  Her laboratory was also the first to discover that increased levels of TGFβ1 causes psoriasis, a common inflammatory skin disease. Using a genetically engineered mouse model expressing TGFb1 in mouse epidermis, she collaborated with many dermatological researchers worldwide discovered a novel molecular targets of  involved in psoriasis.  All of these contributions have provided important insights into novel therapeutic strategies for psoriasis and her mouse model provides a unique tool to test therapeutic interventions in preclinical studies prior to moving them into clinical trials.