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University of Colorado Cancer Center

University of Colorado Cancer Center, A National Cancer Institute-designated Comprehensive Cancer Center
 

Marileila Varella-Garcia, PhD

Preceptor


Specialty:

Medical Oncology

Location: 

University of Colorado Denver, Anschutz Medical Campus

Prerequisites: 

The student must have completed 3 years of college

Number of Openings: 2

Objective: 

The major goals of the ongoing projects are identify prognostic and predictive molecular markers in carcinomas from distinct sites, such as lung, head and neck, colorectal, prostate and breast. Experimental steps include (a) selection of  DNA probes and optimization of fluorescence in situ hybridization (FISH) protocols to apply them in rapid and objective laboratorial tests, and (b) validation in clinical specimens.

Description:

DNA FISH probes are useful reagents for molecular diagnosis of genomic conditions impacting patient survival and response to specific therapies. In the fellowship, the students will be involved in multiple aspects of translational research. They will, under close technical supervision,  (a) prepare specimens for analysis, (b) perform hybridization assays and troubleshoot protocols, (c) collect data performing analysis using fluorescence microscopes, (d) acquire and analyze digital images, (e) organize appropriate databases, and (f) interpret and discuss results according to the literature.