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University of Colorado Cancer Center

University of Colorado Cancer Center, A National Cancer Institute-designated Comprehensive Cancer Center
 

Tamara Terzian, PhD

Preceptor


Specialty:

Oncology

Location:

University of Colorado Anschutz Medical Campus

Prerequisites:

The student must have completed one year of college

Number of Openings: 1

Program Objective:

One major goal of the lab is to define the role of the tumor suppressor p53 and its regulators in tumorigenesis. We are using mice that carry different p53 mutations to assess their impact on tumor initiation and progression.

The second major goal of the lab is to uncover the molecular mechanisms underlying Giant Congenital Nevi (GCN). GCN are present at birth and result from the abnormal proliferation of benign melanocytes in the dermis and epidermis and they carry an elevated risk to convert to melanoma.

Program Description:

Techniques routinely used in the lab include mouse husbandry and necropsies, quantitative PCR, fluorescent in vitro imaging, immunohistochemistry, immunocytochemistry, tissue culture, grafting and virus production.