Cell Growth, Death and Senescence, Signaling Pathways, and Oncogenes and Tumor Suppressor Genes, Gene Regulation and Transcription Factors, Tumor progression, invasion and metastasis, and Experimental and Molecular Therapeutics
University of Colorado Denver, Anschutz Medical Campus, Dept of Dermatology, Aurora
3 Years of college
Number of Openings: 1
To better understand the progression and resistance to therapy of melanoma, and thus to find better treatment strategy
1) To examine the treatment potential of combining a small molecule inhibitor of Bcl-2 family members with conventional therapeutic agents to treat melanoma cells and melanoma-stem cells.
2) To explore the roles of miRNAs in melanoma tumorigenesis and therapeutic potential of miRNA in melanoma treatment.