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2018 Seed Grant Recipients

Congratulations to the CWHR 2018 Faculty Research Development Award Recipients



Thank you to the funders of these awards:
  • The List Family Foundation
  • The Ludeman Family
  • University of Colorado School of Medicine 
Request for Proposals for the the 2019 seed grants will go out in Spring of 2019.

seth_creasy.JPGSeth Creasy, PhD - Division of Endocrinology, Metabolism, and Diabetes

Effects of Menopause on Propensity for Weight Regain
Very little research has been conducted to examine differences in propensity for weight regain, energy expenditure, energy intake, and physical activity between pre- and postmenopausal women following weight loss. The overall aim of Dr. Creasy’s study is to begin to investigate these potential differences, which could lead to individualized prescriptions and strategies for postmenopausal women seeking long-term weight loss.

ramon_lorca.JPGRamón Lorca, PhD - Division of Reproductive Sciences

Effect of High-altitude and Intrauterine Growth Restriction on Potassium Channels in Myometrial Arteries from Pregnant Women
Dr. Lorca is investigating how living at high altitude (>8000 ft.) affects fetal and maternal complications of pregnancy. His research aims to understand the mechanisms by which low oxygen availability alters the effects of pregnancy on uterine vessels. He expects that these studies will improve our understanding of fetal growth retardation and preeclampsia and identify targets for therapeutic or preventive treatments. ​

clare_paterson.JPGClare Paterson, PhD - Department of Psychiatry

Exploration of Antenatal Vascular Endothelial Growth Factor Signaling to Better Understand the Biological Origins of Depression as a Systemic Disease
Females are a particularly vulnerable subpopulation to depression, and there are high rates of co-occurrence of depression and diseases of the vascular system. Dr. Paterson’s research aims to identify the early-life biological origins of depression by examining the relationship between depression-related behaviors and brain vasculature. This research has the potential to identify novel targets that may represent earlier, faster and more effective therapeutic strategies for millions of women suffering from depression worldwide.​

christine_swanson.JPGChristine Swanson, MD, MCR - Division of Endocrinology, Metabolism, and Diabetes

Sleep Disruption, Bone Metabolism, and Insulin Action: Investigating Mechanistic Links and Sex Differences
Women are more commonly affected by osteoporosis than men. However, the effects of altered sleep timing and duration on bone turnover in women and how this may relate to the metabolic risks seen with sleep disruption are unknown. This research will measure markers of bone turnover in women exposed to several weeks of shortened sleep throughout the day to understand if altered sleep timing and duration negatively impact bone turnover in women, as they do in men.

sean_iwamoto.JPGSean Iwamoto, MD - Division of Endocrinology, Metabolism, and Diabetes

Novel Evaluations of Aging and Gender-affirming Hormone Therapy on Vascular Endothelial Function and Metabolic Profiles in Transgender Adults 
Dr. Iwamoto is studying the effects of gender-affirming estradiol treatment on vascular health and metabolic parameters in transgender women. This research will help answer questions about how estrogen impacts the cardiovascular disease risk among transgender women and eventually promote further study of ways to intervene, treat, and prevent cardiovascular disease in these people and the general population.

The VAD Gap: Characterizing Gender Disparities in Ventricular Assist Device Use through Psychosocial Evaluations
Ventricular assist devices (VADs) are a vital treatment option for patients with heart failure, often representing the last option for patients for whom transplants are not feasible. VADs often improve survival and quality of life, but only 15-20% of patients in the U.S. with these devices are women. This research team is investigating whether this disparity could be due in part to bias implicit in the social assessment for VAD candidacy. By understanding social factors which disadvantage women, as well as bias in the evaluation itself, we will be able to develop practices which provide equal access to this lifesaving treatment.

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Prateeti Khazanie, MD, MPH - Division of Cardiology

School of Medicine Bio​





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Christopher Knoepke, PhD, MSW - Division of Cardiology

​School of Medicine Bio​




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Pilar Ingle, MSW, LSW - ACCORDS




Assessing Public Perceptions and Identifying Targets for Intervention to Reduce Disparities in the Provision of Bystander CPR for Women after Cardiac Arrest
Women who suffer out of hospital cardiac arrest receive bystander CPR less than men with the same condition. This statistic has translated into a survival benefit to men, while women continue to have reduced rates of survival after cardiac arrest. This study will assess public perception of gender differences for bystander CPR. The researchers ultimately hope to create an intervention/educational module for basic life support training to reduce this gender disparity.

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Sarah Perman, MD, MSCE - Department of Emergency Medicine




christopher_knoepke.JPG
Christopher Knoepke, PhD, MSW - 
Division of Cardiology

​School of Medicine Bio​




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Kathryn Rappaport, MD - 
Division of Pediatric Emergency Medicine




stacie_daugherty.JPG
Stacie Daugherty, MD, MSPH - Division of Cardiology





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