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Clinical Research: Determinants of Macrovascular Disease Risk in Adolescents With Type 1 Diabetes


 

Principal Investigator: Paul Wadwa, MD; COMIRB #: 07-0780

In type 1 diabetes patients, atherosclerosis (blood vessel plaque) occurs earlier in life compared to the general population without diabetes. The purpose of this research study is to assess risk for cardiovascular disease in adolescents with and with out type 1 diabetes.

Why should you consider this study?

Type 1 diabetes is the leading cause of end-stage kidney disease, blindness and a major cause of cardiovascular disease (heart attack and stroke) and premature death in the general population. In type 1 diabetes patients, atherosclerosis (blood vessel plaque) occurs earlier in life and leads to shorter survival, compared to the general population without diabetes. Atherosclerosis is known to begin in childhood. The purpose of this research study is to assess risk for cardiovascular disease in adolescents with and with out type 1 diabetes.

Who can sign up for this study?

1. You have type 1 diabetes mellitus for more than five years and are between the ages of 12 and 19.
2. You do not have diabetes but are similar in age and gender to someone in the study who has type 1 diabetes.

What will happen in this study?

The study consists of 1 study visit which lasts approximately 2 hours.

If you agree to take part in this study, we will ask you to do the following things:
Have your blood drawn after fasting overnight.
Collect a urine sample.
Have your blood pressure taken.
Have your height and weight measured.
Have my pulse waved analyzed. Pulse wave velocity and Pulse wave analysis is a non-invasive, non-painful probe that is placed on your wrist (radial artery), neck (carotid artery), upper leg (femoral artery), and foot (dorsalis pedis or posterior tibial artery).
Have a brief medical exam.

Who should I call with questions or to schedule an appointment?

Franziska Bishop: 303.724.6764 or Franziska.Bishop@ucdenver.edu
Brittany Aragon: 303.724.7507 or Brittany.Aragon@ucdenver.edu