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Welcome to the Barbara Davis Center for Diabetes at the University of Colorado School of Medicine on the Anschutz Medical Campus in Aurora, Colorado.

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Clinical Division Faculty

Andrea Steck, MD
Assistant Professor of Pediatrics

My primary research focus is in the area of epidemiology, prediction and prevention of type 1 diabetes. I have a background in pediatric endocrinology, with specific training and expertise in pediatric diabetes. My prior research experience includes work with epidemiological studies such as DAISY (Diabetes Autoimmunity Study in the Young), TEDDY (The Environmental Determinants of Diabetes in the Young) and genetic studies such as T1DGC (Type 1 Diabetes Genetics Consortium). At this time, I am the PI for an ADA Career Development Award to look at Determinants of rate of progression to type 1 diabetes in TrialNet subjects at high risk of developing type 1 diabetes. I am also the PI for the TrialNet Pathway to Prevention Study, the TrialNet Oral Insulin Trial and the LIFT (Long-Term Investigative Follow-Up in TrialNet) Study for the University of Colorado. I am the PI for the CYPRESS study (C-peptide in the Young Preservation Study) looking at preservation of C- peptide over time in children diagnosed with type 1 diabetes through prospective studies such as DAISY and TEDDY (JDRF Follow-up of Children Diagnosed with Diabetes Study) compared to a group of age matched type 1 diabetes controls from the community. I am also the PI of the Twin Family Study and the Monogenic Diabetes study at the Barbara Davis Center, investigating monogenic forms of diabetes. In summary, I have demonstrated record of successful and productive research projects in collaboration with local and national colleagues with the DAISY, T1DGC, TEDDY and TrialNet studies.​ 


  1. Steck A, Rewers M. “Epidemiology and Geography of type 1 Diabetes”. International Textbook of Diabetes Mellitus, 3rd edition, 2004, John Wiley & Sons Ltd.

  2. Steck AK, Barriga KJ, Emery LM, Fiallo-Scharer RV, Gottlieb PA, Rewers MJ. “ Secondary attack rate of type 1 diabetes in Colorado families”. Diabetes Care. 2005 Feb;28(2):296- 300.

  3. Steck AK, Bugawan TL, Valdes AM, Emery LM, Blair A, Norris JM, Redondo MJ, Babu SR, Erlich HA, Eisenbarth GS, Rewers MJ.  “Association of Non-HLA Genes With Type 1 Diabetes Autoimmunity”. Diabetes. 2005 Aug;54(8):2482-6.

  4. Aly TA, Ide A, Humphrey K, Barker JM, Steck A, Erlich HA, Yu L, Miao D, Redondo MJ, McFann K, Roberts CM, Babu SR, Norris JM, Eisenbarth GS, Rewers MJ. “Genetic   Prediction of autoimmunity: Initial oligogenic prediction of anti-islet autoimmunity amongst DR3/DR4-DQ8 relatives of patients with type 1A diabetes”.  J Autoimmun. 2005;25 Suppl:40-5. Epub 2005 Oct 19.

  5. Geng DG, Liu SY, Steck A, Eisenbarth G, Rewers M, She JX. “Comment on: Biason-Lauber A, Boehm B, Lang-Muritano M, et al (2005). Association of childhood type 1 diabetes mellitus with a variant of PAX4: possible link to beta cell regenerative capacity.  Diabetologia 48:900-905”. Diabetologia. 2006 49:215-216.

  6. Steck AK, Liu SY, McFann K, Barriga KJ, Babu SR, Eisenbarth GS, Rewers MJ, She JX. “ Association of the PTPN22/LYP gene with Type 1 Diabetes”.   Pediatric Diabetes. 2006 Oct;7(5):274-8.

  7. Steck AK, Klingensmith GJ, Fiallo-Scharer R. “ Recent Advances in Insulin Treatment of Children”.  Pediatr Diabetes. 2007 Oct;8 Suppl 6:49-56. Review.

  8. Steck AK and Eisenbarth GS. “Genetic similarities between latent autoimmune diabetes and type 1 and type 2 diabetes”.  Diabetes. 2008 May; 57(5):1160-2.

  9. Yu J, Steck AK, Babu S, Yu L, Miao D, McFann K, Hutton J, Eisenbarth GS, Klingensmith GJ. “Single NucleotideTranscription factor 7-like 2 (TCF7L2) Gene Polymorphisms in Anti-Islet Autoantibody Negative Patients at Onset of Diabetes”.  J Clin Endocrinol Metab. 2008 Dec 2. [Epub ahead of print].

  10. Liu S, Wang H, Jin Y, Podolsky R, Reddy MV, Pedersen J, Bode B, Reed J, Steed D, Anderson S, Yang P, Muir A, Steed L, Hopkins D, Huang Y, Purohit S, Wang CY, Steck AK, Montemari A, Eisenbarth G, Rewers M, She JX. “ IFIH1 Polymorphisms Are Significantly Associated with Type 1 Diabetes and IFIH1 Gene Expression in Peripheral Blood Mononuclear Cells”.  Hum Mol Genet. 2009 Jan 15;18(2):358-65.

  11. Baschal EE, Aly TA, Jasinski JM, Steck AK, Johnson KN, Noble JA, Erlich HA, Eisenbarth GS; Diabetes Genetics Consortium. “The frequent and conserved DR3-B8-A1 extended haplotype confers less diabetes risk than other DR3 haplotypes”.  Diabetes Obes Metab. 2009 Feb;11 Suppl 1:25-30.

  12. Steck AK, Zhang W, Bugawan TL, Barriga KJ, Blair A, Erlich HA, Eisenbarth, GS, Norris JM and Rewers MJ. “Do non-HLA Genes Influence Development of Persistent Islet Autoimmunity and Type 1 Diabetes in Children with High-Risk HLA-DR,DQ Genotypes?” Diabetes. 2009 Feb 2. [Epub ahead of print]

  13. Baschal EE, Aly TA, Jasinski JM, Steck AK, Noble JA, Erlich HA, Eisenbarth GS; Type 1 Diabetes Genetics Consortium. “Defining Multiple Common “Completely” Conserved Major Histocompatibility Complex SNP Haplotypes”. Clinical Immunol. 2009 Aug;132(2):203-14.

  14. Steck AK, Baschal EE, Jasinski JM, Boehm BO, Bottini N, Concannon P,  Julier C, Morahan G, Noble JA, Polychronakos C, She JX, Eisenbarth GS and the Type I Diabetes Genetics Consortium.  “rs2476601 T Allele T (R620W) Defines High Risk PTPN22 Type I Diabetes- Associated Haplotypes with Preliminary Evidence for an Additional Protective Haplotype”. Genes and Immunity (2009) 10, S21–S26.

  15. Dimorphic Gianani R, Campbell-Thompson M, Sarkar SA, Wasserfall C, Pugliese A, Solis JM, Kent SC, Hering BJ, West E, Steck A, Bonner-Weir S, Atkinson MA, Coppieters K, von Herrath M, Eisenbarth GS. “ Dimorphic histopathology of long-standing childhood-onset diabetes”. Diabetologia. 2010 Apr;53(4):690-8.

  16. Steck AK, Rewers MJ. Genetics of type 1 diabetes. Clin Chem. 2011 Feb;57(2):176-85. Review. PMID:21205883

  17. Steck AK, Armstrong TK, Babu SR, Eisenbarth GS; T1DGC. Stepwise or linear decrease in penetrance of type 1 diabetes with lower-risk HLA genotypes over the past 40 years. Diabetes. 2011 Mars; 60 (3): 1045-1049. PMID 21307077

  18. Steck AK, Johnson K, Barriga KJ, Miao D, Yu L, Hutton JC, Eisenbarth GS, Rewers MJ. Age of Islet Autoantibody Appearance and Mean Levels of Insulin, but Not GAD or IA-2 Autoantibodies, Predict Age of Diagnosis of Type 1 Diabetes: Diabetes Autoimmunity Study in the Young. Diabetes Care. 2011 Jun;34(6):1397-9. PMID:21562325

  19. Baschal EE, Sarkar SA, Boyle TA, Siebert JC, Jasinski JM, Grabek KR, Armstrong TK, Babu SR, Fain PR, Steck AK, Rewers MJ, Eisenbarth GS.  Replication and further characterization of a Type 1 diabetes-associated locus at the telomeric end of the major histocompatibility complex. J Diabetes. 2011 Sep;3(3):238-47. PMID: 21631897

  20. Baker PR 2nd, Steck AK. The Past, Present, and Future of Genetic Associations in Type 1 Diabetes. Curr Diab Rep. 2011 Jul 27. PMID: 21792535

  21. Steck AK, Winter WE. Review on monogenic diabetes. Curr Opin Endocrinol Diabetes Obes. 2011 Aug;18(4):252-8. PMID: 21844708

  22. Steck AK, Wong R, Wagner B, Johnson K, Liu E, Romanos J, Wijmenga C, Norris JM, Eisenbarth GS, Rewers MJ. Diabetes. Effects of Non-HLA Gene Polymorphisms on Development of Islet Autoimmunity and Type 1 Diabetes in a Population With High-Risk HLA-DR,DQ Genotypes. 2012 Mar;61(3):753-8. PMID:22315323

To access a more complete listing of publications, please go to PubMed and use the search term Barbara Davis Center for Childhood Diabetes or enter individual author names.
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