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TG Project Overview


The Thiwáhe Gluwáš’akapi project is designed to accomplish 4 goals:

 1.   Develop a culturally grounded, family-based early substance use prevention intervention tailored to a Northern Plains American Indian reservation.

  • Use an evidence-based program approach to implement a proven program (Iowa Strengthening Families Program for Families and Youth 10-14).
  • Ground the evidence-based program within American Indian culture, using local cultural teachings as the context for delivery of the intervention.

2.   Pilot the adapted program – Thiwáhe Gluwáš’akapi (TG) – to determine feasibility, refine details, and maximize fit within the community. 

3.  Test the adapted program, using the principles of the Multiphase Optimization Strategy for intervention evaluation and development to determine the relative effect sizes of intervention components and inform a final TG program that balances effectiveness and efficiency.  

4.   Set the stage for a randomized controlled trial of the full intervention and, eventually, the broad, sustainable implementation of TG by the tribal health administration.



Thiwáhe Gluwáš’akapi is funded by the National Institute on Drug Abuse

R01DA035111 (Whitesell, PI)

Culturally grounded early substance use prevention for American Indian families


Colorado School of Public Health

13001 E. 17th Place
Mail Stop B119
Aurora, CO 80045

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