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Bert Boyer

I have been actively involved (as Co-I) in all aspects of our COBRE-funded Center for Alaska Native Health Research (CANHR) since the late 1990s. In 2010, I became CANHR Director and PI of the COBRE grant that was renewed for another five years under my leadership. CANHR investigations span the translational cycle (T0-T4) with a strong emphasis on T0-community engagement in research. I was also PI on another NIH R01 grant (HG005221, with Dr. Wylie Burke as dual PI) investigating the ethical dissemination of genetic research results, and I am subcontract PI on our current pharmacogenomics research network center grant (U01GM092676, Drs. Thummel and Burke as PIs). In both of these grants, we have been engaging community members as co-researchers in the data collection and interpretation stages of genetic and pharmacogenomic research. In the current proposal, I will work closely with Ms. Scarlett Hopkins in engaging our Community Advisory Group (CAG) of genetic research past participants to develop a shared understanding of Precision Medicine Research (PMR), soliciting their views on participation and benefit to Yup'ik Alaska Native community members. We will also consult with the CAG to identify PMR vignettes and tribal stakeholders from whom we will collect empiric data on their view of PMR and PM interventions. I will also work closely with tribal leaders at the Yukon-Kuskokwim Health Corporation to discuss preferred approaches to PMR including return of results and data stewardship. Conclusions and key messages will be shared with the CAG and I will participate in a national meeting of tribal representatives, researchers and funders to share our findings and identify facilitators and barriers to PMR in AIAN communities. My experience with NIH grants that involve a number of different types of resources over the past 24 years both as a PI and Co-Investigator, have given me the experience necessary to work collaboratively in a trusting partnership with Alaska Native people, colleagues at the Southcentral Foundation, University of Montana and University of Washington, and to represent the University of Alaska Fairbanks regarding NIH and human health research.

Colorado School of Public Health

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