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University of Colorado Denver College of Liberal Arts and Sciences

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Faculty & Staff Directory

Audrey Hendricks, Ph.D.


Assistant Professor

Email: audrey.hendricks@ucdenver.edu
Website: http://math.ucdenver.edu/~ahendricks
Office Location: CU Building 627
Phone: (303) 315 1722

Areas of Expertise:

Education & Degrees

Ph.D in Biostatistics (2011), Boston University, Graduate School of Arts and Sciences


 

M.A. in Biostatistics (2008), Boston University, Graduate School of Arts and Sciences


 

B.A. in Economics (2002), University of Colorado, College of Arts and Sciences


 

B.A. in Music (2002), University of Colorado, College of Music


 

Bio

In 2002 Audrey earned two BAs from the University of Colorado, Boulder in Economics (Magna Cum Laude) and Music. Audrey then pursued a PhD in Biostatistics at Boston University. During her first two years at BU, Audrey gained experience in clinical trials, ethical conduct, bioinformatics, and statistical genetics through an NIH training grant. She then worked as a graduate research assistant on a variety of projects (Parkinson's Disease, Huntington Disease, mouse, brain, Atrial Fibrillation, etc.) and statistical genetics issues (GWAS, gene-gene interaction, cryptic relatedness, and gene-region summary methods, etc.). During this time Audrey also consulted as a statistical geneticist for the Framingham Heart Study and taught several courses in statistics. In summer 2011, Audrey earned her PhD in Biostatistics.

From 2011-2013 Audrey joined the Wellcome Trust Sanger Institute in Cambridge, England as a postdoctoral research fellow for the obesity arm of the UK10K project. She worked directly with exome sequencing data to find genes that are associated to and cause obesity as well as with the statistical genetics group and UK10K team to parse out general statistical problems that arise when analyzing next generation sequencing data.  Recently, Audrey has joined the University of Colorado-Denver Mathematical and Statistical Sciences department as an Assistant Professor and looks forward to continuing to pursue applied and methodological work in statistical genetics while fostering new and old collaborations.  In addition to statistical genetics, Audrey is interested in a range of statistical applications and issues including big data, public health, bioinformatics, and statistics education.

Select Publications


  1. Hendricks AE, Dupuis J, Logue MW, Myers RH, Lunetta KL. Correction for multiple testing in a gene region. EJHG, 2013. doi:10.1038/ejhg.2013.144.

  2. Hendricks AE, Dupuis J, Gupta M, Logue MW, Lunetta KL: A comparison of gene region simulation methods. PLoS One, 2012; 7:e40925.

  3. Hadzi TC, Hendricks AE, Latourelle JC, Lunetta KL, Cupples LA, Gillis T, Mysore JS, Gusella JF, MacDonald ME, Myers RH, Vonsattel JP: Assessment of Cortical and Striatal Involvement in 523 Huntington Disease Brains. Neurology, 2012 Oct 16;79(16):1708-1715.

  4. Lee JH, Lee JM, Ramos EM, Gillis T, Mysore JS, Kishikawa S, Hadzi T, Hendricks AE, Hayden MR, Morrison PJ, Nance M, Ross CA, Margolis RL, Squitieri F, Gellera C, Gomez-Tortosa E, Ayuso C, Suchowersky O, Trent RJ, McCusker E, Novelletto A, Frontali M, Jones R, Ashizawa T, Frank S, Saint-Hilaire MH, Hersch SM, Rosas HD, Lucente D, Harrison MB, Zanko A, Abramson RK, Marder K, Sequeiros J, Landwehrmeyer GB, Shoulson I, Myers RH, MacDonald ME, and Gusella JF: TAA repeat variation in the GRIK2 gene does not influence age at onset in Huntington’s disease. Biochemical and Biophysical Research Communications, 2012 Aug 3;424(3):404-8.

  5. Dumitriu A, Moser C, Hadzi T, Williamson S, Pacheco C, Hendricks AE, Latourelle JC, Wilk J, Destefano A, Myers RH: Post-mortem Interval Influences α-Synuclein Expression in Parkinson Disease Brain. Parkinson’s Disease, 2012. 614212, doi:10.1155/2012/614121.

  6. Chen H*, Hendricks AE*§, Cheng Y, Cupples LA, Dupuis J, Liu CT: Comparison of statistical approaches to rare variant analysis for quantitative traits. In BMC Proceedings, 2011. 5 Suppl 9:S113. * Co-first authors § Corresponding author

  7. Latourelle JC, Hendricks AE, Pankratz N, Wilk JB, Halter C, Nichols WC, Gusella JF, Destefano AL, Myers RH, Foroud T: Genomewide linkage study of modifiers of LRRK2-related Parkinson’s disease. Movement Disorders, 2011 Sep; 26(11):2039-44.

  8. Hendricks AE, Latourelle JC, Lunetta KL, Cupples LA, Wheeler V, MacDonald ME, Gusella JF, Myers RH: Estimating the probability of de novo HD cases from transmissions of expanded penetrant CAG alleles in the Huntington Disease gene from male carriers of high normal alleles (27-35 CAG). AJMG, 2009. 149A(7): 1375-81.

  9. Hendricks AE, Zhu Y, Dupuis J: Genome-wide association and linkage analysis of quantitative traits: comparison of likelihood ratio test and conditional score statistic. BMC Proceedings 2009. 3 Suppl 7:S100.

  10. Dragileva E, Hendricks A, Teed A, Gillis T, Lopez ET, Friedberg EC, Kucherlapati R, Edelmann W, Lunetta KL, MacDonald ME, Wheeler VC: Intergenerational and striatal CAG repeat instability in Huntington's disease knock-in mice involve different DNA repair genes. Neurobiol Dis 2009, 33:37-47.

  11. Swami M, Hendricks AE, Gillis T, Massood T, Mysore J, Myers RH, Wheeler VC: Somatic expansion of the Huntington's disease CAG repeat in the brain is associated with an earlier age of disease onset. Hum Mol Genet 2009, 18:3039-3047.

  12. Manning AK, Ngwa JS, Hendricks AE, Liu CT, Johnson AD, Dupuis J, Cupples LA: Incorporating biological knowledge in the search for gene x gene interaction in genome-wide association studies. BMC Proceedings 2009. 3 Suppl 7:S81

  13. DeStefano AL, Latourelle J, Lew MF, Suchowersky O, Klein C, Golbe LI, Mark MH, Growdon JH, Wooten GF, Watts R, Guttman M, Racette BA, Perlmutter JS, Marlor L, Shill HA, Singer C, Goldwurm S, Pezzoli G, Saint-Hilaire MH, Hendricks AE, Gower A, Williamson S, Nagle MW, Wilk JB, Massood T, Huskey KW, Baker KB, Itin I, Litvan I, Nicholson G, Corbett A, Nance M, Drasby E, Isaacson S, Burn DJ, Chinnery PF, Pramstaller PP, Al-Hinti J, Moller AT, Ostergaard K, Sherman SJ, Roxburgh R, Snow B, Slevin JT, Cambi F, Gusella JF, Myers RH: Replication of association between ELAVL4 and Parkinson disease: the GenePD study. Hum Genet 2008, 124:95-99.

  14. Latourelle JC, Sun M, Lew MF, Suchowersky O, Klein C, Golbe LI, Mark MH, Growdon JH, Wooten GF, Watts R, Guttman M, Racette BA, Perlmutter JS, Ahmed A, Shill HA, Singer C, Goldwurm S, Pezzoli G, Zini M, Saint-Hilaire MH, Hendricks AE, Williamson S, Nagle MW, Wilk JB, Massood T, Huskey KW, Laramie JM, DeStefano AL, Baker KB, Itin I, Litvan I, Nicholson G, Corbett A, Nance M, Drasby E, Isaacson S, Burn DJ, Chinnery PF, Pramstaller PP, Al-Hinti J, Moller AT, Ostergaard K, Sherman SJ, Roxburgh R, Snow B, Slevin JT, Cambi F, Gusella JF, Myers RH: The Gly2019Ser mutation in LRRK2 is not fully penetrant in familial Parkinson's Disease: the GenePD study. BMC Medicine 2008, 6.

  15. Tobin JE, Latourelle JC, Lew MF, Klein C, Suchowersky O, Shill HA, Golbe LI, Mark MH, Growdon JH, Wooten GF, Racette BA, Perlmutter JS, Watts R, Guttman M, Baker KB, Goldwurm S, Pezzoli G, Singer C, Saint-Hilaire MH, Hendricks AE, Williamson S, Nagle MW, Wilk JB, Massood T, Laramie JM, DeStefano AL, Litvan I, Nicholson G, Corbett A, Isaacson S, Burn DJ, Chinnery PF, Pramstaller PP, Sherman S, Al-Hinti J, Drasby E, Nance M, Moller A, Ostergaard K, Roxburgh R, Sherman SJ, Roxburgh R, Snow B, Slevin JT, Cambi F, Gusella JF, Myers RH: Haplotypes and gene expression implicate the MAPT region for Parkinson disease: the GenePD Study. Neurology 2008, 71:28-34.

  • Courses Taught