Reviewers with appropriate expertise will evaluate eligible applications with a specific emphasis on research that furthers the CCTSI mission. Recommendations will be presented to the CCTSI Executive Committee for approval. All Executive Committee decisions will be final. Short informative critiques of application strengths and weaknesses will be provided to all applicants in February after selection notifications are made.
Is the proposal
innovative and novel in its hypotheses, approaches, and techniques? Does the application represent a changing
research direction or a transition to a new area of research that broadens an
investigator’s research program in clinical and translational areas?
- Approach/Scientific Merit
Are the hypotheses and experimental approach sound? What is the likelihood of success given the experiments / proposal as outlined? Are there explicit plans for development of future funding for the project, whether from the NIH, foundations, or commercial sources?
- Cross-disciplinary or Collaborative Focus
Does the research involve a new collaboration, especially one that increases its translational nature? Are attempts made to bridge basic and translational researchers in discovery translation?
- Significance, especially to the CCTSI Mission
Will the results further our understanding / diagnosis / prevention/ or treatment of human diseases?
Do the investigators have the necessary expertise and capacity to complete the proposed research? Have the investigators made use of new collaborations? Are attempts made to integrate basic and translational researchers in discovery translation? Are efforts made to collaborate with community researchers or community members, if relevant? Is the Multiple PI Plan appropriate, if applicable?
Does the research environment improve the likelihood that the proposed research can be completed and have an impact? Does the proposal consider use of CCTSI resources, including Design, Biostatistics, Technology Resources, Patient and Clinical Interaction Resources etc.?