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Anschutz Medical Campus

University of Colorado Denver

Gates Grubstake Fund

Regenerative Medicine and Stem Cell Technologies


The Gates Center for Regenerative Medicine and CU Innovations are pleased to announce the Gates Grubstake Fund focused on accelerating basic, clinical, and translational research related to the field of regenerative medicine.

  • Treatments (e.g. biologics, small molecules, cell therapies)
  • Diagnostics, platforms and research tools (e.g. biomaterials, scaffolds, therapeutic targets, cell expansion methods)
  • Devices (e.g. drug delivery, implants, restoration)
  • Cell biology and tissue engineering

Investigators are encouraged to apply if their programs fall within or even adjacent to these fields.

Interested investigators affiliated with the University of Colorado, Children’s Hospital Colorado, and the UCHealth System are encouraged to submit an application. Multiple awards will be granted, the funding limit is $350,000 per award.  


  • Please fill out the application form which can be found online at this link.
  • Please contact Heather Callahan, with any questions
  • Applications are due by 5 pm Monday, August 26, 2019
  • Investigators whose applications are selected for presentation will be notified in September 2019
  • Presentations to the Investment Committee are planned for November 2019
  • Awardees are expected to be notified in December 2019
A downloadable version of this RFP can be obtained here.


Past Winners

Gates Grubstake Fund 2018
  • ​Prevention and treatment of pulmonary fibrosis, Ken Liechty, M.D.
  • Heart regeneration by conversion of non-myocytes into functional cardiomyocytes,
    Kunhua Song, Ph.D.
  • Generation of engraftable hematopoietic stem cells from induced pluripotent stem cells,
    Mike Verneris, M.D.​

Gates Grubstake Fund 2017

  • Stem Cell-Derived Retinal Transplant to Treat Dry AMD, Maria Valeria Canto-Soler, Ph.D.

  • Clinical Development of Autologous CD117+ Progenitor Cell Therapy for Solid Organ Transplantation, Martin Zamora, M.D.

  • Bioresorbable 3-D Printed Personalized Implant for Cartilage Regeneration in Pediatric Growth Plate Injuries, Karin A. Payne, Ph.D. 

Gates Grubstake Fund 2016

  • Dr. David Wagner: A Novel Therapeutic to Impact Myelin Loss/Regeneration in Multiple Sclerosis 
  • Dr. Kenneth Liechty: Conjugated Nanoceria to Treat Oxidative Stress and Prevent Chronic Inflammation: First Use Treating Diabetic Ulcers
  • Dr. Jeffrey Olson: Intraocular Device to Potentiate Retinal Stem Cell Transplantation in Macular Degeneration 


·       Ganna Bilousova, Ph.D., and Igor Kogut, Ph.D.: Induced pluripotent stem cell services as a platform for clinical research

·       Steven Dow, DVM, Ph.D., and Mary Ann DeGroote, M.D.: Antimicrobial stem cell therapy for infected diabetic foot ulcers

·       Karin Payne, Ph.D., and Vikas Patel, M.D.: Structural living bone allografts to enhance bone formation in orthopedic surgery


·       Xiao-Jing Wang, M.D., Ph.D.: Human Smad7-based proteins combined with a cell permeable peptide called Tat.  Tat-Smad7 and its derivatives can be used via topical application to treat at least four diseases: oral mucositis, psoriasis, chronic wounds, and fibrotic diseases.

·       Antonio Jimeno, M.D., Ph.D.: Proprietary humanized mouse model to assess cancer treatments​