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University of Colorado Denver


Nanotoxicology Lab

Lab News

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Mar 26: Jared presented work on silver nanoparticle toxicity at the symposium entitled, “Comprehensive Analysis of Nanosilver Toxicity Profiles: Known, Unknown and Surprises!” which was chaired by Drs. Sri Nadadur and Linda Birnbaum during the Society of Toxicology Annual Meeting.

Mar 25: Wei and Jonathan presented posters on protein corona formation and vascular nanoparticle toxicity respectively at the Society of Toxicology Annual Meeting.

Mar 24: Jonathan won the best postdoctoral fellow award from the Nanotoxicology Specialty Section at the Society of Toxicology Annual Meeting.

Mar 22: Jared presented a lecture on Nanotechnology Health and Safety at the Undergraduate Education Program during the Society of Toxicology Annual Meeting in San Diego, CA.

Feb 26: Hari Sowrirajan, a high school freshman working in the lab under the guidance of Dr. Shannahan, placed first in the regional science fair and was invited to the state science fair as well as the Intel International Science and Engineering Fair in Pittsburgh, PA.

Feb 18: Monica Sandoval joined the lab as a Toxicology PhD candidate.

Feb 11: Our R25 undergraduate training grant was funded by NIEHS. The project entitled, “Colorado Undergraduate Research in Environmental Health Sciences” will start this summer with recruitment of 6 undergraduates from the University of Colorado Denver to work in research labs across the Anschutz Medical Campus.

Jan 23: We hosted the first Nanomedicine & Nanotoxicology symposium at the University of Colorado Anschutz Medical Campus.

Jan 5: Our multi-center NIEHS consortium publication with the University of California-Davis and NYU entitled, “Influence of Particle Size on Persistence and Clearance of Aerosolized Silver Nanoparticles in the Rat Lung” was accepted for publication in Toxicological Sciences.


Dec 20: Jared delivered a Plenary Lecture on Nanotechnology Health and Safety at the Frontiers in Nano Science, Technology and Applications International Conference at the Sri Sathya Sai Institute of Higher Learning, Prasanthinilayam, India.

Oct 13: Abdul’s first paper was accepted in Toxicology In Vitro entitled, "Influence of Physicochemical Properties of Silver Nanoparticles on Mast Cell Activation and Degranulation”.

Oct 7:  Jonathan’s paper entitled, “Formation of a Protein Corona on Silver Nanoparticles Mediates Cellular Toxicity via Scavenger Receptors” was accepted for publication in Toxicological Sciences. 

Sept 15:  Our invited collaborative perspective article entitled, “Illuminating Nano-Bio Interactions: A Spectroscopic Perspective” was accepted for publication in a special issue of the MRS Bulletin. 

Aug 8:  Our paper with Dr. Chris Wingard entitled, “PVP Formulated Fullerene (C60) Increases Rho-Kinase Dependent Vascular Tissue Contractility in Pregnant Spraque Dawley Rats” was accepted for Publication in Reproductive Toxicology.

August 1:  Jared was elected as vice-president of the Mountain West Society of Toxicology.

July 1: Jared was appointed as the Director of Toxicology Graduate Program for the Department of Pharmaceutical Sciences.

June 2: Our NIH R03 grant entitled, “Nanoparticle-Protein Corona Structural Changes and Immunoreactivity” was funded. 

May 29: Our collaborative paper with Dr. Feng Ding entitled, “Effect of Fullerenol Surface Chemistry on Nanoparticle Binding-Induced Protein Misfolding” was accepted for publication in Nanoscale.

May 28: Our collaborative paper with Dr. Chris Wingard entitled, “Vascular Tissue Contractility Changes Following Late Gestational Exposure to Multi-Walled Carbon Nanotubes or Their Dispersing Vehicle in Sprague Dawley Rats” was accepted for publication in the Journal of Nanomedicine & Nanotechnology.

May 19: Jonathan won an outstanding abstract award from the Environmental, Occupational, and Population Health Assembly at ATS.

May 18-21: Jonathan and Jared presented carbon nanotube toxicity studies at the American Thoracic Society annual meeting in San Diego, CA.

April 22-26: Jared and Jonathan presented at the 7th International Nanotoxicology Congress in Antalya, Turkey.

April 10th: Hari Sowrirajan, an 8th grade student at the Challenge School who was mentored by the Jonathan, won 1st place at the Colorado State Science fair for his work entitled, “Soak Up The Sun: Using Nanoparticles to Catalyze Water Vaporization”. Congratulations to Hari.

April 1st: Indu Persaud, a Pharmaceutical Sciences graduate student, joined the lab.

March 25: Abdul and Jonathan presented their work on silver nanoparticle toxicity at the 2014 SOT Annual Meeting.

March 24: Jared was elected as a councilor for the Nanotoxicology Speciality Section of SOT.

March 23: Jonathan accepted the Colgate-Palmolive Postdoctoral Fellowship award at the SOT Awards Ceremony.

January 9: A manuscript from our collaborators entitled, “C60 Exposure Augments Cardiac Ischemia/Reperfusion Injury and Coronary Tone in Sprague-Dawley Rats” was accepted in Toxicological Sciences.

January 6: Our SOT symposium article entitled, “Symposium Overview: From Immunotoxicity to Nanotherapy: The Effects of Nanomaterials on the Immune System” was accepted in Toxicological Sciences.


December 30: Our manuscript entitled, “IL-33 Modulates Chronic Airway Resistance Changes Induced by Multi-Walled Carbon Nanotubes” was accepted in Inhalation Toxicology.

December 11: Our new Cytoviva enhanced darkfield hyperspectral imaging system was set-up in the lab.

November 25: Our invited opinions paper, “Engineered Nanomaterial Exposure and the Risk of Allergic Disease” was accepted in Current Opinions in Allergy and Clinical Immunology.

November 8: Jonathan won the Society of Toxicology Colgate Palmolive Fellowship Award in In Vitro Toxicology. The award is presented to one postdoctoral fellow each year and provides $44,000 for stipend and research costs. Jonathan will be presented the award at the 2014 SOT annual meeting in Phoenix, AZ.

September 19-20: The lab attended and presented oral and poster presentations at the Mountain West Society of Toxicology Annual Meeting in Albuquerque, NM. The theme of the meeting was Nanotoxicology. Jonathan won the best postdoctoral presentation award and was selected to be the postdoctoral representative for the regional chapter.

August 1:  Our proteomics paper on silver nanoparticle-protein corona was accepted in PLOS ONE.

July 8:  Wei Bai joined the Nanotoxicology Lab as a postdoctoral fellow. 

July 1:  Our SOT symposium proposal was accepted for the 2014 meeting in Phoenix.  It is entitled, “Three dimensions of nanomaterial pulmonary toxicity:  Innate immunity, TLRs and inflammasomes”.  Drs. Sri Nadadur and Jared Brown are chairing the session and our invited speakers include Drs. Andrij Holian, Jamie Bonner, Tara Sabo-Attwood and Alex Star.


July 1:  We relocated the Nanotoxicology Lab from the Brody School of Medicine at East Carolina University to the Skaggs School of Pharmacy, Departmental of Pharmaceutical Sciences, University of Colorado Anschutz Medical Campus.

Both Jonathan Shannahan and Abdul Aldossari relocated to Colorado to continue their fellowship and graduate studies respectively.