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Mass Spectrometry Facility

Instrumentation






A​​​gilent 6210 TOF
Time-of-flight mass spectrometer equipped with Agilent 1290 UPLC and electrospray ionization (ESI).  Typical uses for this instrument are metabolomics and small molecule analysis.​​




Agilent 6520 Q-TOF
A quadrupole-time-of-flight mass spectrometer equipped with Agilent 1290 UPLC and electrospray ionization (ESI).  T​his instrument is typically used for proteomics, metabolomics (occasionally), and structural identification using MS/MS fragmentation.




Agilent 6550 quadrupole time-of-flight (Q-TOF) mass spectrometer
A quadrupole-time-of-flight mass spectrometer equipped with Agilent 1290 UPLC and electrospray ionization (ESI).  The ESI source is equipped with Agilent iFunnel technology, resulting in higher sensitivity.  Typical uses for this instrument are metabolomics, small m​olecule analysis, proteomics (occasionally), and structural identification using MS/MS fragmentation.




​Agilent 6560 IM-Q-TOF
An ion mobility quadrupole-time-of-flight mass spectrometer equipped with Agilent 1290 UPLC and electrospray ionization (ESI).  Typical uses for this instrument are metabolomics, small molecule analysis, and structural identification using MS/MS fragmentation.  A unique feature of this mass spectrometer is the ability to separate ions based on their collision cross section.  This adds an extra dimension of separation that occurs after chromatography and ionization.​





Agilent 6410 QQQ
A triple quadrupole mass spectrometer equipped with Agilent 1200 HPLC and electros​pray ionization (ESI).  This instrument is typically used for quantitative assays.




Agilent 6490 QQQ
A triple quadrupole mass spectrometer equipped with Agilent 1290 UPLC and electrospray ionization (ESI).  The ESI source is equipped with Agilent iFunnel technology, resulti​ng in higher sensitivity.  This instrument is typically used for quantitative assays.




Bruker EVOQ QQQ
A triple quadr​upole mass spectrometer equipped with Bruker Advance UHPLC and electrospray ionization (ESI).  This instrument is typically used for quantitative assays.




Bruker Compact Q-TOF
A quadrupole​-time-of-flight mass spectrometer equipped with Dionex UltiMate 3000 UHPLC and electrospray ionization (ESI).  This instrument is typically used for metabolomics, small molecule analysis, and structural identification using MS/MS fragmentation.




Bruker Impact Q-TOF
A quadrupole-time-of-flight mass spectrometer equipped with Bruker NanoAdvance UHPLC and elect​rospray ionization (ESI).  This instrument is typically used for proteomics.




Bruker Scion GC-MS
A
 single quadrupole mass spectrometer equipped with gas chromatography and electron ionization (EI).  This instrument is typically used for small molecule analysis.  A unique feature of this in​strument is the capability to do headspace GC.




Bruker amaZon ETD
A quadrupole ion trap mass spectrometer equipped with nanoflow liquid chromatography and electrospray ionization (ESI).  This instrument is typically used for high sensitivity prot​eomics.  Two fragmentation modes are offered with this instrument, electron transfer dissociation (ETD) and collision-induced dissociation (CID).  ETD and CID fragment ions by different mechanisms, providing rich and complimentary structural information.




ABI 4800 Plus MALDI-TOF/TOF)
A time-of-flight/time-of-flight mass spectrometer equipped with matrix assisted laser desorption ionization (MALDI).  This instrument is typically used for high sensitivity, high mass accuracy data in very short time frames, as well as MS/MS fragmentation.