Skip to main content
Sign In

University of Colorado Denver

​​​​​​​​​ ​
 

High Throughput and High Content Screening Core Facility

Costs and Authorship


​​

Please note that it is very difficult to estimate the total cost of a screening campaign until a number of factors are known. This includes, but is not limited to:

  • How much HTS/HCS method development and validation is required
  • The complexity of the assay (Number of manipulations, difficulty of data analysis)
  • Core Facility instrumentation used
  • Number of compounds or libraries screened
  • Data handling and storage


Hourly charges for equipment usage can be found here:

School of Pharmacy Users

Other University / Non-Profit Users

 

Notes on Authorship

Co-authorship is generally expected when core personnel have made significant contributions to the research in the form of consultation, experimental design, method development, data analysis and/or data interpretation. Significant is defined as “the project would not have progressed, or progressed at a substantially slower pace, without the guidance of facility personnel”. In such cases, core personnel should have the opportunity to review and edit the appropriate sections of a manuscript before submission.

Acknowledgement of facility contributions is expected in publications that include any data generated in the facility or using core instrumentation or software. An example of an appropriate acknowledgement is “The authors wish to thank the High Throughput and High Content Screening Core at the University of Colorado Anschutz Medical Campus for their contributions to this manuscript”.

Please inform us when relevant publications are accepted, as we would like to post citations on our website. This information is vital to the continued support of the facility.

Grant Assistance and Percent Effort

We are very happy to provide letters of support and assistance in grant writing. For letters of support, please allow at least 2 weeks from the time of your request. Please furnish the following information: Title of grant, agency to which you are submitting the grant, your title and mailing address, and 1-3 sentences on the goals (or specific aims) of your proposal.

Our facility is also dependent on grant support for long-term success and we appreciate your support in keeping the facility funded. To determine if percent effort by core personnel is required, please consider the following:

  1. Does the proposal include a specific aim(s) that focuses on high throughput screening and/or high content analysis?
  2. Is method development is required?
  3. Is data analysis development required (often the case with high content work)?
  4. Would the aim or proposal not receive a favorable review without the support of Core personnel?
  5. Would the project not have progressed, or progressed at a substantially slower pace, without the guidance of facility personnel?
Rate for School of Pharmacy Members
SERVICE Minimum Time (min) Base Rate ($)  
Plate Reader/Facility Staff 30 38.54 PR per 1/2 hr
Plate Reader/Trained Personnel 30 14.12 PR per 1/2 hr
HCS/Facility Staff 60 101.09 HCS per hour
HCS/Trained Personnel 60 46.55 HCS per hour
HCS Remote Analysis 60 17.53 HCR per use
Robotic Liquid Handler 60 96.34 RB per hour
All other HTS equip/Facility Staff 30 63.91 OT per 1/2 hr
all other HTS equip/Trained Personnel 30 14.12 OT per 1/2 hr
Data Prep 60 88.21 DT per hour
Method Development 60 91.43 MD per hour

 

* The robotic liquid handler is for use only by HTS/HCS Core Staff. If a potential user demonstrates commitment to a screening project and a minimum of three hours of hands-on training on the robot from HTS staff, then a Trained User rate can be arranged. This is for both the safety of the lab environment and the user, as well as the continued dependability of the instrument.

** All other HTS Instrumentation refers to the plate washer, the bulk liquid dispenser, the plate sealer, and general facility usage. There is no charge for use of the CO2 incubator for HTS/HCS projects.

 

Rate for Non-SOP Members
SERVICE Minimum Time (min) Base Rate ($)  
Plate Reader/Facility Staff 30 61.36 PR per 1/2 hr
Plate Reader/Trained Personnel 30 34.54 PR per 1/2 hr
HCS/Facility Staff 60 147.00 HCS per hour
HCS/Trained Personnel 60 72.15 HCS per hour
HCS Remote Analysis 60 17.53 HCR per use
Robotic Liquid Handler 60 116.38 RB per hour
All other HTS equip/Facility Staff 30 83.96 OT per 1/2 hr
all other HTS equip/Trained Personnel 30 36.90 OT per 1/2 hr
Data Prep 60 111.33 DT per hour
Method Development 60 111.47 MD per hour

 

* The robotic liquid handler is for use only by HTS/HCS Core Staff. If a potential user demonstrates commitment to a screening project and a minimum of three hours of hands-on training on the robot from HTS staff, then a Trained User rate can be arranged. This is for both the safety of the lab environment and the user, as well as the continued dependability of the instrument.

** All other HTS Instrumentation refers to the plate washer, the bulk liquid dispenser, the plate sealer, and general facility usage. There is no charge for use of the CO2 incubator for HTS/HCS projects.