Pharmaceutical Sciences Faculty

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Antiviral drug pharmacokinetic-pharmacodynamic relationships in humans
Autism Spectrum Disorders and Epilepsy
Autoantigen discovery in autoimmune diseases
Behavioral responses to alcohol
biomarkers
Biomarkers
Biophysical characterization of protein vaccine stability and aggregation
Biophysical characterization of therapeutic macromolecules
Bladder Cancer
Cancer Biology
Cancer Pharmacology
Cancer Pharmacology of Natural Products
CAR T and engineered T cell therapies of autoimmune diseases
Cardiovascular Diseases
Cells as carriers of drugs and diagnostics
Chemical synthesis of heterocyclic compounds
Chronic kidney disease of unknown origin (CKDu)
Clinical Pharmacogenomics
Complement-mediated tissue damage
Computational chemistry
Computational-based design of novel small molecules
Creating extensive DNA and RNA sequence information for rat strains to be used in systems analysis of physiology and behavior
cytochrome P450 enzymes
Developing novel technology to improve drug oral bioavailability
Development of medications to be used for prevention of relapse in alcoholics
Development of medications to treat chronic pain syndromes and reduce opiate use
Development of software solutions
Discovery and Translation of Novel Treatment Approaches to Kidney Diseases
Disrupting drug resistance mechanisms in cancer (DNA damage response)
Drug Design
Drug Mechanism(s) of Action
drug metabolism and disposition
drug-drug interactions
Drug-induced kidney toxicities
Ecological Roles of Natural Products
Environmental causes of neurodegeneration e.g. maneb exposure
Environmental causes of neuronal injury
enzymology
Examination of social learning and behaviors in the autistic brain
Extracellular vesicles and organ-organ crosstalk
Genetics of drug efficacy and toxicity
Genetics of substance use disorders
Heart Transplantation
HIV
Host-Microbiome-Environment Interactions
HTS/HCS Drug Discovery
Identifying new bio-analytical methodology
Immune recognition of nanoparticles
Immunology and nanoformulations/drug delivery systems
Immunotherapy and natural immunosuppression
In vitro and In vivo Pharmacokinetics and Toxicology
In vitro and In vivo Pharmacology
In Vivo and In Vitro Drug Metabolism and Transport in Kidney
In vivo electrophysiology of brain activity
Inflammation and immune responses to particulates
Inhibitory neurotransmission in health and disease
Innate immunity and chronic liver diseases
Innovation and entrepreneurship
Isolation of biomarkers and cells from bulk fluids
Mass spectrometry
Mass Spectrometry Tools for Microbial Systems
Mast cells and allergy
Mathematical modeling of pharmacokinetic data
Mechanisms of alcoholic liver disease
Mechanisms of plasticity in the developing brain
Mechanisms of T cell mediated metal hypersensitivities
Mechanisms of T cell recognition of autoantigens in Type 1 diabetes and RA
Mechanisms of transcriptional regulation
Medicinal Chemistry - rational drug design and Structure-Activity Relationship (SAR) elucidation
Metabolic consequences of mitochondrial dysfunction
Metabolic dysregulation of liver and kidney function
Metabolomics lipidomics and proteomics
Mitochondrial (dys)function and oxidative stress in epilepsy and neurodegeneration
Molecular and Cancer Biology
Molecular biology immunology and nanotechnology
Multi-omics data integration
Nanomedicine and Nanosafety
Nanomedicines for drug delivery gene delivery and imaging
Neuroinflammation and redox signaling
New assays for drug/metabolite quantification in unique compartments in humans
Novel drug delivery systems: Nanoparticles microparticles and implants.
Novel informatics strategies applied to metabolomics
Novel therapies for diabetic retinopathy macular degeneration and cancers.
Nutrimetabolomics
Ocular respiratory and brain drug discovery delivery and development
Organic and Medicinal Chemistry
Pathogenesis of Type 1 Diabetes
pediatrics
Pharmacokinetics
Pharmacokinetics and Pharmacodynamics
Post-translational modifications
Preclinical and clinical development of drugs and biologics
pregnant women
Proteostasis and neurodegeneration
Public Science Communication
Quantitative RNA sequencing
Redox signaling and drug design in the immune diseases and infectious diseases
Redox-based small molecule therapeutics
Regulatory nature of sirtuin activity and protein acetylation
Role of oxylipins in inflammatory immune and lung disease
Science and Medical Journalism
Statistical methods and bioinformatics techniques for studying complex genetic traits
Structure stability and aggregation of protein drug substances and drug products
Structure-function-disease analysis of dystrophin and muscular dystrophy
Systems genetics
T cell immunology
Targeting adaptive proteins and pathways in hypoxia (metabolic reprogramming)
The genetic predisposing factors for alcoholism and other addictions
Thermodynamics of protein-protein and protein-DNA interactions
Thiol redox dysregulation in mechanisms of toxicity
Transcriptomics and systems genetics
tuberculosis
Understanding role of host:microbiome metabolism in health and disease
Using drug concentrations to assess adherence to antiviral therapies
Utilizing mass spectrometry to investigate proteomics & post-translational modifications
Warfare vesicants

Rajesh Agarwal PhD

Professor Cancer Prevention and Control Program Co-Leader

Department of Pharmaceutical Sciences University of Colorado Cancer Center

Research Focus: Cancer Biology Cancer Pharmacology Warfare vesicants

Email:rajesh.agarwal@cuanschutz.edu

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Julio Aguado PhD

Assistant Professor

Department of Pharmaceutical Sciences

Email:julio.aguadoperez@cuanschutz.edu

Tom Anchordoquy BS, MA, PhD

Professor

Department of Pharmaceutical Sciences

Email:tom.anchordoquy@cuanschutz.edu

Research Profile

Peter Anderson PharmD

Professor

Department of Pharmaceutical Sciences

Research Focus: Antiviral drug pharmacokinetic-pharmacodynamic relationships in humans New assays for drug/metabolite quantification in unique compartments in humans Using drug concentrations to assess adherence to antiviral therapies

Email:peter.anderson@cuanschutz.edu

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Christina Aquilante PharmD

Professor Director of Pharmacogenomics for the Colorado Center for Personalized Medicine, Debra Devereaux Endowed Chair in Translational Pharmaceutical Sciences

Department of Pharmaceutical Sciences CU/UCHealth

Research Focus: Cardiovascular Diseases Clinical Pharmacogenomics Heart Transplantation

Email:christina.aquilante@cuanschutz.edu

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David Bain PhD

Professor Vice-Chair

Department of Pharmaceutical Sciences

Research Focus: Biophysical characterization of therapeutic macromolecules Mechanisms of transcriptional regulation Thermodynamics of protein-protein and protein-DNA interactions

Email:david.bain@cuanschutz.edu

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Farnoush Banaei-Kashani PhD

Associate Professor

Email:farnoush.banaei-kashani@ucdenver.edu

Winona Booher

Data Analyst

Email:winona.booher@cuanschutz.edu

Gina Bouchard PhD

Assistant Professor

Department of Pharmaceutical Sciences

Email:gina.bouchard@cuanschutz.edu

Research

Jonathan Boyd

Assistant Professor

Email:jonathan.w.boyd@cuanschutz.edu

Kristina Brooks PharmD

Assistant Professor

Department of Pharmaceutical Sciences

Research Focus: biomarkers drug-drug interactions HIV pediatrics Pharmacokinetics pregnant women tuberculosis

Email:kristina.brooks@cuanschutz.edu

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Jared Brown PhD

Professor Toxicology Graduate Program Director, T32 Training Program in Molecular and Systems Toxicology Director, Colorado Center for Nanomedicine and Nanosafety Co-Director

Department of Pharmaceutical Sciences

Research Focus: Bladder Cancer Chronic kidney disease of unknown origin (CKDu) Inflammation and immune responses to particulates Mast cells and allergy Nanomedicine and Nanosafety

Email:jared.brown@cuanschutz.edu

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Carlos Catalano PharmD, PhD

Professor

Department of Pharmaceutical Chemistry

Email:carlos.catalano@cuanschutz.edu

Research Profile

Caleb Chandler PhD

Post-Doctoral Fellow

Department of Pharmaceutical Sciences

Email:caleb.chandler@cuanschutz.edu

Shaodong Dai PhD

Professor

Department of Pharmaceutical Sciences

Research Focus: CAR T and engineered T cell therapies of autoimmune diseases Mechanisms of T cell mediated metal hypersensitivities Mechanisms of T cell recognition of autoantigens in Type 1 diabetes and RA Redox signaling and drug design in the immune diseases and infectious diseases

Email:shaodong.dai@cuanschutz.edu

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Thomas Delong Dr. rer. nat

Assistant Professor

Department of Pharmaceutical Sciences

Research Focus: Autoantigen discovery in autoimmune diseases Mass spectrometry Pathogenesis of Type 1 Diabetes Post-translational modifications T cell immunology

Email:thomas.delong@cuanschutz.edu

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Kristofer Fritz PhD

Associate Professor

Department of Pharmaceutical Sciences

Research Focus: Mechanisms of alcoholic liver disease Metabolic dysregulation of liver and kidney function Regulatory nature of sirtuin activity and protein acetylation Utilizing mass spectrometry to investigate proteomics & post-translational modifications

Email:kristofer.fritz@cuanschutz.edu

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