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University of Colorado Denver

 

Mechanisms and Barriers in Nanomedicine

Future Dates TBA


There is a growing sentiment in the field that in order to increase the availability of nanodrugs for patients, the biological, pathophysiological, immunological and manufacturing/regulatory barriers to effective translation need to be addressed.

The goals of the two-day Mechanisms and Barriers in Nanomedicine workshop are to: 

  • provide an educational forum on the barriers to nanoparticle translation; 
  • provide a paradigm shift to overcome these problems; and
  • allow for open discussion among faculty, postdocs and graduate students, to trigger new ideas and concepts.


Untitled Document

Fundamental issues in nanomedicine

Anchordoquy

 

Complement and immune uptake of nanomedicines: lessons from iron oxide nanoworms

Dmitri Simberg

 

Keynote: Tumor-penetrating peptides in nanoparticle targeting

Erkki Ruoslahti

 

Where the wild things are: Perivascular regulation of tumor cell dormancy and drug resistance

Cyrus Ghajar

 

Immunotherapy targeting tumor microenvironment and opportunities for nanomedicine

Stephen Dow

 

Improving nano-drugs' therapeutic efficacy through their interaction with tumor microenvironment

Chezy Barenholz

 

Physical and chemical mechanisms  of targeting selectivity for  mRNA nanomedicines for tumor immunotherapy

Heinrich Haas

 

Nanobioconjugates delivered through multiple biobarriers regulate laminin-411 - Notch  pathways

Julia Ljubimova

 

Exploiting cells in the tumor microenvironment for nanovector based therapy

Biana Godin

 

The 4S parameters in the rational design of nanomedicines

Paolo Decuzzi

 

Biologics and peptides by a novel encapsulation process

Robert Prud'homme

 

Optimizing nanoparticle delivery of chemotherapeutics - The clinical challenge

Alberto Gabizon

 

Impact of nanoparticles on the tumor immunologic milieu: Promise and peril

Irene La-Beck

 

Nanoparticle-based MRI on tumor associated macrophages: preclinical and clinical utility

Natalie Serkova

 

Translation of a cancer nanotherapeutic into the clinic: A view from the trenches

Len Pagliaro

 

Preclinical immunotoxicity studies of nanotechnology-formulated drugs

Marina Dobrovolskaia

 

Perspective on nanomedicine climate and the science advances

Dorothy Farrell

 

Hyperthermia approaches for enhanced delivery of polymer therapeutics

Hamid Ghandehari

 

Biophysical barriers in respiratory drug delivery

Hugh Smyth

 

To target or not to target: Lessons from RNAi-based targeted lipid-based nanoparticles

Dan Peer

 

Extracellular vesicles-mediated penetration of therapeutic compounds in solid tumors

Ji Ho (Joe) Park

 

Nanoparticle-prodrug combination approach for treating neuroblastoma

Michael Chorny

 

Nanoghosts as a natural nonviral gene delivery platform for targeting cancers

Marcelle Machlouf

 

Best poster talks

 

Impact of Motif Organization on the Formation and Stability of Silk-Elastin like Protein Polymer Nanogels

Martin Jensen (University of Utah)

 

Nanoscale Colloids & Particles for High Intensity Focused Ultrasound (HIFU)-Initiated Imaging

Nicholas Blum (University of Colorado Boulder)

 

Hearing and seeing nanoparticle targeting with photoacoustic imaging

Jack Ho (Princeton University)

 




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Event Sponsors

CU School of Pharmacy     CU Cancer Center     Quidel     



The AAPS Rocky Mountain regional discussion group (RMDG) is also a sponsor.