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 Results From Research and Clinical Trials : Selected site
TitleStudy GoalsEligibility CriteriaContact Information
Do you have Atopic Dermatitis (Eczema)? HS-2581
To study eczema
Males and Females between 3 and 80 who have atopic dermatitis or males and females between 8 months and 80 who have a history of, or an active case of eczema hereticum (wide-spread herpes skin infection along with atopic dermatitis.
PI: Leung, Donald
  • 303-398-1409
  • taylorp@njhealth.org
Better Control of Type 2 Diabetes May Decrease Your Risk for Cardiovascular Disease. 10-0644
To look at the use of an extended release formula of Exenatide compared to a placebo to maintain normal glucose levels. Ultimately to see better control of diabetes and a decrease in cardiovascular disease events.​
Person 18+ with Type 2 Diabetes and take no more than 2 diabetes medications with stale doses for the last 3 months. Must not have a planned or anticipated revascularization procedure, but may have a history of cardiovascular disease and must see your primary care physician at least twice a year.
PI: Rasouli, Neda
  • 303-399-8020 X2059
  • chantal.underkofler@ucdenver.edu
Type 2 Diabetes and Exercise Research Study 10-1393
To research the effects of an investigational drug on exercise capacity and blood vessel function​.​
Person 30-60 with Type 2 diabetes who exercise vigorously less than one hour per week and have normal blood pressure. Must not have smoked for at least one year and have a BMI between 25-39.9.
PI: Schauer, Irene
  • 720-848-6690
  • Ellen.Lyon@ucdenver.edu
Are you a Non-smoking Adult between the ages of 45 and 85? HS-1883a
We are interested in learning more about smoking related lung disease, and need healthy non-smoking participants.
45-85 years old Non-Hispanic White or African American No smoking history No evidence of lung disease
PI: Bowler, Russ
  • 303-270-2827
  • prices@njhealth.org
Volunteers needed to Participate in a Research Study about Rheumatoid Arthritis 01-675
The purpose of this study is to learn more about how rheumatoid arthritis develops by studying people who do not have rheumatoid arthritis. Your participation in this study will help us determine if certain genetic and environmental factors affect the chances of developing RA-related autoantibodies in absence of rheumatoid arthritis.
You may be eligible to participate in the study if: -You are at least 40 years old -You do NOT have Rheumatoid Arthritis (RA)
PI: Norris, Jill
  • 303-724-7510
  • Marie.Feser@ucdenver.edu
Restoring Insulin Secretion (RISE) 13-0122
The Children’s Hospital Colorado Clinical Translational Research Center and the National Institutes of Health are conducting a study. This study is aimed at testing whether early treatment is beneficial to kids with early type 2 diabetes and kids at high risk of diabetes.
10-19 years of age, Pubertal, Overweight, Fasting glucose: >90 mg/dl; Impaired glucose tolerance: >140 mg/dl; Pre-diabetes or diagnosed with diabetes for less than 6 months; Metformin
PI: Nadeau, Kristen
  • 720-777-6143
  • susan.gross@childrenscolorado.edu
Do You Smoke? 12-0181
To figure out how these lung substances work in people who drink too much alcohol, who usually smoke, compared to those who do not drink heavily, but who smoke.
Smoking and nonsmoking males
PI: Burnham, Ellen
  • 303-724-6081
  • Carrie.Higgins@ucdenver.edu
Parents or Legal Guardians of Children with Disabilities 12-1664
Assistive Technology Partners, University of Colorado, Anschutz Medical Campus, is performing a study investigating the impact Socially Assistive Robotics has on motor, communication and cognitive skills of children with disabilities.
Children between the ages of 18 months to 5 years of age Have Significant motor and communication disabilities/delays NOT been diagnosed with blindness or deafness They are without a seizure disorder or with a well-controlled seizure disorder They have been on stable medication regime for the past 12 weeks, if they are currently taking medication.
PI: Sandstrum, Jim
  • 303-315-1287
  • Jim.Sandstrum@ucdenver.edu
Help Us Learn About Schizophrenia! 12-1186
Help us learn more about a new drug that may improve thinking and concentration in people with schizophrenia.
We are looking for: Male and female adults who smoke 18-50 years old No previous or current mental illness No drug use Willing to use nicotine patch during study hospital visit If female, willing to use birth control during the study
PI: Freedman, Robert
  • 303-724-6214 or 303-724-7373
  • psypharmresearch@ucdenver.edu
Research Trial Evaluating a New Drug in Psoriasis: Now Enrolling 14-1692
The study will evaluate an investigational drug compared to a currently approved psoriasis medication. Your participation will provide valuable information to researchers seeking new and improved therapies. You will be given either Humira, placebo, or the investigational drug for up to 28 weeks, after which you may be switched over to the active drug depending on your response.
You may be eligible to participate if 18 years of age or older and have been diagnosed with moderate to severe plaque-type psoriasis for at least 6 months.
PI: Alkousakis, Theodore
  • 720-848-0556
  • psoriasiscolorado@ucdenver.edu
Do you have high blood pressure? 13-3174
Study to help predict if blood pressure medications will work for you.
You may be eligible if you are an adult aged 30-80 with a diagnosis of uncontrolled essential hypertension. You must not have a history of end stage liver or renal disease, cannot be pregnant, and cannot be allergic to metoprolol.
PI: Monte, Andrew
  • 303-724-7871
  • Glenn.McWilliams@ucdenver.edu
Volunteers Needed for a Research Study about Rheumatoid Arthritis 15-2288
The purpose of this study is to learn more about rheumatoid arthritis. Your participation in this study will help us determine if gum disease affects the chances of developing protein markers associated with rheumatoid arthritis.
1. You are at least 18 years old 2. You do NOT wear dentures 3. You do NOT take antibiotics prior to any dental work or cleaning 4. You HAVE rheumatoid arthritis diagnosed in the last 3 years OR you HAVE lupus or Sjogren’s syndrome diagnosed at any time in the past
PI: Kelmenson, Lindsay
  • 303-724-0071
  • Laura.Lenischarry@ucdenver.edu
Healthy Females Needed 07-0816
For brain imaging research study on how the brain works with we taste sweets or receive money. Your participation could help us to develop treatments and preventive measures for anorexia nervosa and obesity
Healthy females 16 to 35 who are right-handed, free of medication with no serious medical conditions, permanent metal implants or braces/retainers, and are at a healthy body weight.
PI: Frank, Guido
  • 720-777-4026
  • megan.shott@ucdenver.edu
Give Us a Hand 12-1084
To better understand Multiple Sclerosis in children and teens.
Between the ages of 3-20 AND have Multiple Sclerosis diagnosed before 18 OR Do not have MS
PI: Schreiner, Teri
  • 303-724-3635
  • Ildiko.Torok@ucdenver.edu
Are you an African American with asthma? HS-2805
 We are studying why some African American people have trouble with their asthma despite taking asthma medications.
 Children age 5-17 and non-smoking Adults age18 and older who have asthma symptoms despite asthma treatment • African American ancestry (have at least one    African American grandparent)
PI: Wechsler, MD, Michael
  • 303-398-1443
  • sundstromd@njhealth.org
Do you have human growth hormone (hGH) deficiency? 13-2629
Primary: To demonstrate a clinical superiority of MOD-4023 over placebo in terms of decrease in Fat Mass (FM) in adult subjects with Growth Hormone Deficiency Secondary a. To determine the efficacy of MOD-4023 over placebo in other body composition variables (such as lean body mass and waist-to-hip ratio) b. To evaluate the safety and tolerability of MOD-4023 over placebo in adult subjects with GHD c. To determine the IGF-I and IGFBP-3 serum levels
Adult men and women aged 23 to 70 years of age diagnosed with either adult or childhood onset growth hormone deficiency (GHD).
PI: Wierman, Margaret
  • 720-848-7710
  • Shannon.Moore@ucdenver.edu
Do you have an egg allergy? HS-2764
To see if taking Baked Egg Therapy vs. Oral Immunotherapy may help egg-allergic children tolerate eggs.
males and females 3 to 16 years old, with documented egg allergy, ability to make regular visits to National Jewish Health for up to 2 years.
PI: Leung, Donald
  • 303-398-1618
  • ReamesR@NJHealth.org
Randomized Trial to Prevent Vascular Events in HIV (REPRIEVE) 15-0023
Pitavastatin is a statin that along with diet is used for the treatment of high cholesterol. It also lowers triglyceride levels in the blood. The main purpose of this clinical trial is to see if pitavastatin can prevent heart disease and heart disease related deaths in people with HIV infection who are taking HIV medications.
This study lasts about 6 years (21 visits) and you may be eligible if: • You have HIV and are between the ages of 40 and 75. • You have been on antiretroviral therapy (ART) for at least 6 months. • You have a CD4+ cell count > 100. • You have no history of cardiovascular disease (history of heart attack or stroke, etc.). • You are not currently using a statin drug.
PI: Campbell, MD, Thomas
  • 303-724-0712
  • graham.ray@ucdenver.edu
Are You a Healthy Individual Looking to Help With Research 09-0816
This is a research study to learn more about the risk factors, features, and treatment or prevention efforts for bleeding disorders.
Aged 1 to 17 Healthy
PI: Manco-Johnson, Marilyn
  • 303-724-3856
  • taylor.blades@ucdenver.edu
Are you interested in participating in a research study to help us learn more about where the fat tissue in your body originates? MYTH Study 15-1779
This research study plans to learn more about where the fat cells in your body come from.  Understanding the origin of fat cells is important because it may help to determine the health of fat cells and why fat that is stored in some places of your body is more "unhealthy" than other fat.
We are enrolling men and women who are: Age 21-40 y or 55-85 y; BMI 22-35 kg/m2; Weight stable (not actively gaining or trying to lose weight); Non-active to moderately active (exercise ≤ 3 days/wk lasting < 30 min); Not taking any hormonal therapy (testosterone, estrogen/progesterone replacement, or hormonal contraceptives); Not diagnosed with type 2 diabetes or taking glucose or lipid lowering medication; Not pregnant or planning to become pregnant in the next month
PI: Gavin, Kathleen
  • 303-724-7472
  • kathleen.gavin@ucdenver.edu
Research study on the effects of an investigational drug on weight and neuronal response 15-0650
This research study plans to examine the effects of an investigational new drug on neuronal, physiological, and behavioral mechanisms of obesity in the general population.
To be eligible for the study, participants must have a BMI greater than 27 kg/m2, be 21-65 years old, be a non-smoker, have no known cardiovascular disease, have no significant endocrine/metabolic disease, must not be pregnant or trying to conceive, and must be able to complete an MRI scan.
PI: Tregellas, Jason
  • 303-724-8299
  • brainstudy@ucdenver.edu
Volunteers Needed for a Research Study about Rheumatoid Arthritis 15-2288
The purpose of this study is to learn more about rheumatoid arthritis by studying people who do not have rheumatoid arthritis. Your participation in this study will help us determine if gum disease affects the chances of developing protein markers associated with rheumatoid arthritis.
You are at least 40 years old • You do NOT have rheumatoid arthritis (RA)
PI: Kelmenson, Lindsay
  • 303-724-0071
  • Laura.Lenischarry@ucdenver.edu
Feasibility Study of Metformin Therapy in ADPKD 16-0802
The primary purpose of the research study is to determine the safety and tolerability of the study drug (Metformin or placebo) when given to subjects with ADPKD (Autosomal Dominant Polycystic Kidney Disease).
Age 30 - 60 Confirmed diagnosis of ADPKD Estimated glomerular filtration rate between 50 and 75 mL/min/1.73 m2, inclusive Controlled blood pressure at < 130/80 mmHg on a stable antihypertensive regimen for at least 4 weeks
PI: Brosnahan, Godela
  • (303) 724-7790
  • taylor.struemph@ucdenver.edu
We are Currently Enrolling People with Down syndrome for a study in Dr. Pelak's Brain and Vision Research lab at the University of Colorado Anschutz Medical Campus. 05-1131
To examine visual brain function in people with mild memory impairments to detect early signs of Alzheimer's Disease.​
Persons 19-30 who have Down Syndrome
PI: Pelak, Victoria
  • 303-724-2184
  • Jerri.Lusk@ucdenver.edu
EMERALD STUDY: Effects of MEtformin on CardiovasculaR function in AdoLescents with Type 1 Diabetes 12-1528
​To determine the effects of Metformin on Cardiovascular Function in Adolescents with Type 1 Diabetes.
  • Persons 12-21 who have Type 1 Diabetes
  • Non-smoker, able to ride a stationary bike
  • You must be willing to take metformin or placebo (sugar pill) for 3 months.
  • Other exclusions apply, please contract study for more information
PI: Nadeau, Kristen
  • 720-777-5774 or 720-777-6143
  • susan.gross@childrenscolorado.oramy.baumgartner@childrenscolorado.org
Exercise and Cancer Prevention Research Study 13-2314
The goal of this study is to better understand the biological mechanisms associated with exercise and reduced risk for breast cancer.
  • You must be a female between the ages of 30-45 to participate in this study. 
  • You must be planning to live in the Denver metropolitan area for the next 10 consecutive months. 
  • You should not be a regular exerciser because this study is for people who do not exercise right now; however, you should be willing to participate in an exercise program 4 times per week for 16-weeks.
PI: Bryan, Angela
  • 303-492-9549
  • cuchange@colorado.edu
Are you interested in a supervised exercise intervention? 13-3252
Volunteers are needed for a research study to examine the effects of exercise on food intake and appetite regulation.
  • 21-45 years old
  • Non- smoker
  • Non- Diabetic
  • Exercise no more than 1 time a week
  • Maintained your current weight for last 6 months
  • Have a body mass index (BMI) of 27-35 (check it out at http://nhlbisupport.com/bmi/)
PI: Cornier, Marc
  • 303-724-9024
  • allison.hild@ucdenver.edu
Study of Mood Disorder in Preschool Children 07-0932
We are doing a research study to better understand what mood disorders look like in preschool children.
We are looking for volunteers who:  
  • Are parents of children between the ages of 4 and 6 years 0 months.
  • Are in one of three groups:
    1. Their child has no major mental health problems, and there is no family history of major mood or psychotic disorders.
    2. Their child has been diagnosed with a mood disorder, bipolar disorder, or mood dysregulation disorder. 
    3. Their child has been diagnosed with attention deficit hyperactivity  disorder (ADHD).  
  • Parents or guardians will be asked to:
    • Read and sign a consent form
    • Participate in interviews about their children
  • The  children will be asked to:
    • Participate in a story game
    • Take tests of verbal and nonverbal abilities
How much time will this take?
The visit for the child will last from 1 to 2 hours.  The visit for the parents will last 3 to 5 hours.
PI: Ross, Randy
  • 303-724-6200
  • Kate.Noonan@ucdenver.edu
Understanding how Tysabri and Gilenya Influence the Quality of your Daily Life with Multiple Sclerosis 13-2767
The purpose of this research study is to compare two medications, Tysabri and Gilenya, used in the treatment of multiple sclerosis (MS), through a few self-reported patient surveys. We will ask you to complete online surveys about overall health-related quality of life, disability, fatigue, cognition and productivity. We will also want to review your medical records to understand your MS history with your permission. This study will help us understand how these drugs are impacting each aspect of your daily lives.
  • Between ages 16 and 65
  • Scheduled to start natalizumab or fingolimod for the first time to treat your MS
PI: Nair, Kavita
  • 303-724-8388
  • Eric.Engebretson@ucdenver.edu
Living with MS? 12-1522
To evaluate the safety of a new investigational drug that may help reduce relapses.
  • Between the ages of 18 to 65
  • Participants must have relapsing-remitting multiple sclerosis (RRMS)
PI: Corboy, John
  • 303-724-7421
  • Kristina.Bliss@ucdenver.edu
Are you Pregnant or a Nursing Mother? Consider being a part f a Breast Cancer Research. 12-0769
This study will examine changes that occur in the breast tissue, blood and urine of a woman after she has given birth to a child. The study will examine how a woman’s breast and her cells change after pregnancy and breast feeding and how her immune system interacts with these changes. The immune system is a complex network of cells that identify our tissues as “self” or “foreign” as well as normal cells or cancer cells. We hope to discover how a woman’s breast changes after pregnancy or breast feeding to see if this time point in a woman’s life could be targeted to prevent breast cancer.
You are being asked to be in this research study because you are pregnant or were recently pregnant and have not had breast cancer or another autoimmune disease.
PI: Borges, Virginia
  • 303-724-6077
  • emily.rozzo@ucdenver.edu
DO YOU HAVE GESTATIONAL DIABETES? Would you like help with your GDM Diet? 14-1358
Research Subjects Needed to Participate in a Diet Research Study in Women with Gestational Diabetes
Who can qualify? * Highly motivated pregnant women with Gestational Diabetes not taking medicine for blood sugar control * Women willing to follow 1 of 2 healthy diets for blood sugar control * Women willing to complete 5 visits during pregnancy with infant follow up * Gestational age: <31 weeks; singleton pregnancy * Healthy  women, age : 20-39 years * No high blood pressure
PI: Hernandez, Teri
  • 303-724-8966
  • Nicole.Hirsch@ucdenver.edu
Volunteers needed for a NASH therapeutic trial 14-2108
Clinical research study of an investigational product for the treatment of non-alcoholic steatohepatitis (NASH)
*≥18 years old *Confirmed diagnosis of NASH *No other liver disease *No excessive alcohol use (no more than 2 drinks/day for women and 3 drinks/day for men)
PI: Bambha, Kiran
  • 303-724-1871
  • colin.jenks@ucdenver.edu
We are looking for adolescents who have received a solid organ transplant for a telehealth group research study! 13-2997
Learning how to improve adherence in adolescents who have received solid organ transplants and determining whether telehealth can be used to facilitate groups for teenage transplant recipients.
Teens between the ages of 13 and 17 who have received a heart, liver, or kidney transplant.
PI: Buchanan, Cindy
  • 720-777-5529
  • cindy.buchanan@childrenscolorado.org
Study of Pre and Postnatal Infant Brain Growth and Development 15-0707
Through a study of infants before and after pregnancy, researchers at Children's Hospital Colorado and the University of Colorado Denver will investigate the impact of mother and infant nutritional health on infants' cognitive development.
* That mom (you) was at least 18 when you had your child. * Delivered full term (at least 37 weeks).  * English speaking (as one of the household languages). * Your child was part of a singleton pregnancy.  * No abnormalities found on the fetal ultrasound and no serious complications during delivery.  * No smoking, drinking, recreational drug use or prescription drug abuse during pregnancy. * No diabetes before or during the pregnancy.  * No high blood pressure before or during the pregnancy.  * No metal in or on your child’s body that would make it unsafe for him/her to have an MRI scan. 
PI: Deoni, Sean
  • 720-777-8756
  • info@childimaginglab.org
Help Us Learn More about Care Decisions at End-of-Life . . . A Hospice Decision-Making Research Project 16-0479
The goal of this project is to conduct a needs assessment to learn what information patients, providers and informal caregivers think should be included in hospice decisional support materials.
-Cared for a loved one with advanced illness -Have lots of illnesses or advanced illness? -Have you or a loved one considered hospice -Are you willing to participate in a focus group and/or personal interview to share your experiences and opinions about major decisions near the end of life? OR -Are a doctor, nurse, social worker, clergy member or another professional that works with seriously ill patients -Do you volunteer with hospice or with patients making end-of-life care decisions? -Do you have experience with referring patients to hospice? -Do you have experience caring for patients in hospice? -Do you have experience caring for patients near death? -Are you willing to participate in a focus group and/or personal interview to share your experiences and opinions about major decisions near the end of life?
PI: Matlock, Dan
  • 303-724-8985
  • channing.tate@ucdenver.edu
Be a part of Cancer Research 11-0357
We are looking for women who have not been diagnosed with cancer to participate in a research study.
Older than 18 Be willing to make a one-time blood donation Not be diagnosed with an immune disease such as diabetes or rheumatoid arthritis
PI: Borges, Virginia
  • 3037246077
  • emily.rozzo@ucdenver.edu
We are looking for Healthy Men and Women to participate in the WATCH CALORIE Research Study 15-1570 15-1570
The study will examine how diet impacts circadian clocks in abdominal fat tissue
Healthy men and women aged 20 to 35 years A BMI between 25-35 Exercise less than 4 days per week Have a regular sleep schedule
PI: Rynders, Corey
  • 720-848-6472
  • Corey.Rynders@ucdenver.edu
Research Near You 16-0663
Investigate potential treatment options for FSGS or Minimal Change Disease
Have had a biopsy to diagnosis FSGS or Minimal Change Disease, are 6 years of age or older, and are struggling to manage proteinuria (the medical term for spilling protein.
PI: Thurman, Joshua
  • 303-724-8781
  • karissa.fetrow@ucdenver.edu
REHABILITATION AFTER YOUR TOTAL HIP REPLACEMENT 16-0956
To investigate the effects of two physical therapy programs designed to integrate hip and core muscle strength and function after total hip replacement.
VETERANS between 50-85 years of age who: 1) Will receive a total hip replacement in the near future due to hip osteoarthritis 2) Have no significant pain in the non-surgical leg 3) Have no other conditions that limit ability to participate in rehabilitation
PI: Stevens-Lapsley, Jennifer
  • 303-724-9590
  • kristine.gerron@ucdenver.edu
Type 2 Diabetes and Exercise Research Study 11-0909
Perceived exertion during exercise
Person 50-70 with or without Type 2 diabetes who exercise vigorously less than one hour per week and have normal blood pressure.  You should have a BMI between 25-35 and have not smoked for a least one year.
PI: Huebschmann, Amy
  • 303-724-2255
  • Ian.Leavitt@ucdenver.edu
Participants Needed for an Exercise Study for People with Multiple Sclerosis 14-0295
Researchers from the Neurophysiology of Movement Laboratory on the University of Colorado Boulder campus and the Multiple Sclerosis Center on the University of Colorado Anschutz Medical Campus are conducting a study to investigate the capacity of neuromuscular electrical stimulation to improve walking in persons with multiple sclerosis.
-Between 18 to 55 years of age -Have clinically confirmed diagnosis of MS -Are able to talk but have some difficulty walking
PI: Enoka, Roger
  • 303-724-4644
  • Roger.Enoka@colorado.edu
Help test a mobile app for postpartum moms 14-1173
This research study will test a mobile application to learn more about how to best deliver information about diet and physical activity for postpartum women at elevated risk for diabetes and heart disease.
You may qualify for this study if you:  Are between 18-45 years old  Are in your third trimester of pregnancy or have given birth in the last 24 weeks  Have a postpartum BMI: 25-45 kg/m2  Have access to and be willing to use a wi-fi enabled iPhone or an iPod  Have a history of one or more of the following complications in your most recent pregnancy: o Gestational diabetes mellitus o Preeclampsia o Gestational hypertension o Pre-term delivery (32-37) weeks o Small for gestational age (
PI: Nicklas , Jacinda
  • 303-724-8898
  • jessica.jaramillo@ucdenver.edu
Healthy Individuals needed for Genetic Study of Granulomatous Interstitial Lung Disease. HS-2765
To investigate genetic factors associated with the disease sarcoidosis.
Must be 18 years or older with no history of chronic lung disease (including asthma) or connective tissue/rheumatological disease. Participants must complete a questionnaire and have a small blood draw.
PI: Maier, Lisa
  • 303-398-1730
  • mrozp@njhealth.org
Social Networks of Abused Prescription Pills in Youth (SNAPPY) Research Study 15-0504
The purpose of this research study is to learn more about the misuse of prescription pills and the risk for injection drug use.
You may be selected to participate in the study if you are: • Between the ages of 15 and 24 • Willing to provide information about people in your life and things you do with them • Currently using prescription opioids without a doctor’s prescription or in ways other than what was prescribed OR • Currently using heroin after a period of misusing prescription opioids
PI: Al-Tayyib, Alia
  • 720-504-8012
  • Alia.AlTayyib@dhha.org
A Study to Evaluate Dolutegravir plus Lamivudine Dual Therapy for the Treatment of Naive HIV-1-Infected Participants 15-1624
The main purpose of this study is to evaluate how well a two-drug combination of study drugs (dolutegravir plus lamivudine) will suppress HIV at 24 weeks after starting treatment. The study will also look at the safety and tolerability of this study drug combination, and factors that may affect how well it works in different individuals.
-HIV-1 infected men and women at least 18 years of age -Have not taken HIV medications (except for successful prevention of HIV infection) -No evidence of resistance to the type of anti-HIV drugs being used in the study -Have blood HIV level (viral load) of at least 1000 copies/mL but less than 500,000 copies/mL -No active Hepatitis B infection
PI: Campbell, MD, Thomas
  • 303-724-0712
  • graham.ray@ucdenver.edu
Do you like food? 13-1786
Participants needed for a study on foods Participants in this study will: - Rate a series of food pictures - Watch pictures of food during fMRI recording, to measure brain responses to the pictures - Complete an fMRI task with images shown briefly before food pictures. - May also eat a buffet-style breakfast and lunch. - Be compensated for their time (between 2-6 hours)
- Adults between 15-65 years old - BMI > 25
PI: Legget, Kristina
  • 303-724-8502
  • Brainstudy@ucdenver.edu
HEALTHY WOMEN NEEDED 15-0474
To understand reproduction hormones and fertility potential. To understand how weight affects reproductive health and fertility potential
Be a healthy women age 21-39 with BMI between 18.5 and 24.9 or greater than 30  Have regular menstrual cycles (25-40 days)  Not currently using hormones (like birth control medication)  Be willing to have frequent blood samples drawn
PI: Polotsky, Alex
  • 303-724-5276
  • Katherine.Kuhn@ucdenver.edu
Volunteers Needed for a Research Study about Rheumatoid Arthritis 15-2280
The purpose of this study is to learn more about how rheumatoid arthritis develops by studying patients with very early disease.
You may be able to participate in the study if: You are at least 18 years old You have rheumatoid arthritis that was diagnosed within the past year You have not been treated with any rheumatoid arthritis medications except prednisone
PI: Deane, MD/PhD, Kevin
  • 303-724-1129
  • TIP-RA@ucdenver.edu
The Cellular Pharmacology of F-TAF in dried blood spots “TAF-DBS” 16-0972
The University of Colorado School of Pharmacy is seeking generally healthy individuals for a research study to test medication levels in blood and hair samples.
We are looking for men and women who are: - HIV and Hepatitis B virus negative, and not at risk for HIV - Age 18-59 years - Able to come to short weekly visits on the Anschutz Medical Campus
PI: Anderson, Peter
  • 303-724-8296
  • cricket.mchugh@ucdenver.edu
Help Science. Get Compensated. Sign up for a research study on worry, sleep, and the brain! 15-1593
Participants will: - Complete tests of worry and thinking skills - Wear a sleep watch to record sleep at home - Get a complete MRI scan of their brain Participants receive compensation for their time and effort, plus a copy of the images from their brain scan.
Participants must be: - Between the ages of 13 and 18 - Have no braces or metal implants - Have no serious medical conditions
PI: Mullin, Benjamin
  • 720-777-5086
  • emmaly.owens@ucdenver.edu
Are you using the Mirena® IUD for birth control or to control your heavy menstrual bleeding? 16-2326
The purpose of the study is to evaluate the effectiveness of Mirena® beyond 5 years, up to 8 years of use at preventing a pregnancy. Additionally, the study would assess menstrual blood loss, bleeding patterns and safety during the extended use. The results of this study may allow women to continue use of the Mirena® beyond 5 years, up to 8 years. Help researchers understand if extended use of Mirena® is effective and safe by participating in the clinical trial.
• Women between 18 and 35 years old • You are currently using Mirena® for contraception OR contraception and heavy menstrual bleeding • You have been using the same Mirena® for at least 4.5 years and are able to show documentation of the original date of insertion and indication for use • You are willing to use Mirena® as your main form of contraception • You are sexually active with a male partner who has not had a vasectomy
PI: Teal, Stephanie
  • 303-724-2013
  • rebecca.seale@ucdenver.edu
Looking for HIV-negative smokers to participate in a research study on smoking and lung disease 13-2986
This study is looking at how lung disease is affected by HIV/AIDS.
We need volunteers who:  Smoke  Are between 18-70 years old  Are HIV-negative
PI: Lozupone, Catherine
  • 303-724-0762
  • Christine.Griesmer@ucdenver.edu
MS Volunteers Needed for Research Study 12-1388
Looking to see if there is a cognitive improvement with the treatment of oral estriol as compared to oral placebo
We are looking for: • Women 18-50 years old • Diagnosed with definite relapsing-remitting, secondary-progressive multiple sclerosis or primary-progressive multiple sclerosis • MS disease duration of 15 years or less • On stable dose of standard MS treatment with Copaxone®, Betaseron® (or Extavia®), Rebif®,Avonex®, Gilenya®, Aubagio®, Tecfidera®, or no treatment ----You are not eligible for the study if you are pregnant, breast-feeding, smoke, or have other serious medical conditions.
PI: Corboy, John
  • 303-724-6351
  • Nicola.Haakonsen@ucdenver.edu
JUST DIAGNOSED WITH SHINGLES? 13-2122
This study will look at the body's immune response (how the body fights infection) to the onset of shingles. 1-2 study visits for blood draws, over the course of 3 months.
18+ years of age; NO PRIOR HISTORY of shingles; have NEVER received the shingles vaccine; have DEVELOPED SHINGLES within the last 10 days.
PI: Levin, Myron
  • 303-724-2454
  • nancy.lang@ucdenver.edu
protein and infant growth: Do you have a child younger than 6 months 14-0139
Participants in this research study on protein from complementary foods (meat or dairy) and infant growth, will learn how protein consumption affects your child’s growth, fat gain, and gut health from 6 to 12 months of age.  
To qualify, you child needs to be: 1. Formula fed, or not on breast-milk longer than 1 month. 2. Younger than 6 months. 3. Generally healthy. You will receive commercially available complementary foods for 7 months, Receive infant formula at no cost for 7 months, You will know your child's body fat and fat free mass and blood lipid level.
PI: Krebs, Nancy
  • 303-724-3248
  • minghua.tang@ucdenver.edu
Do You or Someone You Know Suffer From Relapse Remitting Multiple Sclerosis (RRMS)? 13-2209
The University of Colorado Denver is conducting a clinical trial to evaluate the effectiveness, safety and tolerability of two doses of oral administration of laquinimod in subjects with Relapse Remitting Multiple Sclerosis (RRMS). Patients that suffer from RRMS may experience a gradual increase of their disability over time. The purpose of this study is to find out whether laquinimod is safe and effective in slowing the rate of disability progression.
-Between the ages of 18 and 55 -Have clinically confirmed diagnosis of Multiple Sclerosis (MS) with relapse onset disease or relapsing-remitting disease course -Have had at least one documented relapse within 12 months prior to starting this study -Have not been treated with Natalizumab (Tysabri) or Rituximab 2 years prior to starting this study
PI: Vollmer, Timothy
  • 303-724-6351
  • Nicola.Haakonsen@ucdenver.edu
Healthy Minority Volunteers Needed 13-0427
This study plans to learn more about how tenofovir and emtricitabine (Truvada) build up in cells in blood and hair. Participation will include two 12 week dosing periods separated by a 12 week washout period (total duration is 36 weeks). Eligible participants will be given the supply of medications for the study.
Documented negative testing for HIV and hepatitis B Not at risk for HIV Study population balanced by Caucasian, African-American, Hispanic race. African American and Hispanic participants are currently needed. Age 18-50 years Able to meet study personnel on Anschutz Medical Campus for directly observed dosing with study medication, or by audio-visual communication with a mobile cellular device when off Campus
PI: Anderson, Peter
  • 303-724-8296
  • Kayla.bushman@ucdenver.edu
Participate in a research study about body image dissatisfaction and psychosocial distress among breast cancer patients 15-0004
The purpose of this research study is to 1) determine the feasibility and impact of a 2 day body image workshop on breast cancer patients’ body image dissatisfaction, depression, and quality of life and 2) understand the relationships between body image, quality of life, and depression among patients with breast cancer.
Participants must be: 1) between the ages of 18-65, 2) histological or cytological confirmation of breast cancer (any clinical stage is allowed); 3) within 6 months of completion of surgery or final chemotherapy/radiation treatment for breast cancer, 4) experiencing concerns specific to body image.
PI: Pearson-Mauro , Adria
  • 720-251-4803
  • cubodyimage@gmail.com
Would you like to follow your baby's brain development? Study of Pre and Postnatal Infant Brain Growth and Development 15-0707
will examine brain development during and after pregnancy, investigating different aspects of mother and infant nutritional health on your infant’s brain growth and cognitive development.  
As an expectant mother you can participate if you are less than 22 weeks pregnant; or if your healthy newborn infant is between 3 and 15 months of age.
PI: Deoni, Sean
  • 720-777-8036
  • info@childimaginglab.org
Adults (18-55) and Children (8-14) with Asthma 15-1262
This research study is being done to find the amount of cockroach extract that we need to put in the nose to cause nasal symptoms.  
-Be 18 to 55 or 8 to 14 years old -Have a history of asthma
PI: Liu, Andrew
  • (720)777-8077
  • pascuala.pinedo-estrada@childrenscolorado.org
Are you pregnant and do you have lupus, rheumatoid arthritis or type 1 diabetes? 16-0541
We need your help to study possible causes of these autoimmune disorders.  Your baby’s umbilical cord can help us!  Qualifications include:
Adult (18 and older) pregnant women with SLE, type 1 diabetes, or RA Any race and ethnicity.
PI: Pelanda, Roberta
  • 303-724-8666
  • Roberta.Pelanda@ucdenver.edu
Are you a male interested in a supervised diet or exercise intervention? 13-3252
Volunteers are needed for a research study to examine the effects of exercise on food intake and appetite regulation
• Male • 21-55 years old • Non- smoker • Non- Diabetic • Exercise no more than 1-2 times per week (less than 120 minutes/week) • Maintained your current weight for last 6 months • Have a body mass index (BMI) of 27-35 (check it out at http://nhlbisupport.com/bmi/)
PI: Legget, Kristina
  • 303-724-9024
  • allison.hild@ucdenver.edu
Parkinson’s Patients: Can Neurologic Music Therapy Improve Your Fine Motor Skills ? 16-2308
To study the rehabilitative power of music on fine motor skills via brain "entrainment",
Inclusion: 45-85 YO patients diagnosed with Parkinson's disease. Exclusion: (1) features suggestive of other causes of parkinsonism, including cerebrovascular disease or history of major head trauma (2) inability to move their fingers or hands (3) Hoehn and Yahr stage 4 or higher (4) ferrous metal implants which may interfere with the MEG data acquisition and/or be an MRI safety (5) dementia (6) participants engaged in other research studies involving music therapies (7) participants whose insurance does not cover OT costs or who have no insurance
PI: Buard, Isabelle
  • 303-724-5973
  • Isabelle.Buard@ucdenver.edu
Research Study: Good Tastes 15-2437
Some children react more to bitter taste than others. This research will study children’s response to bitter tasting vegetables.
For you to participate in this study, you must: • Live within 75 miles of the University of Colorado Denver Anschutz Medical Campus • Be between 18 – 50 years of age Your child must: • Be between 6 and 24 months of age • Have been born at term (at least 37 weeks gestation) • Must not have allergies or medical conditions
PI: Johnson, Susan
  • 303-724-2922
  • kameron.moding@ucdenver.edu
Diabetic Male and Female Volunteers Needed for Exercise Research Study 06-0062
Evaluate exercise function during single leg calf exercise in people with or without type 2 diabetes
Healthy Adults 30-70 with Type 2 diabetes but not using insulin. Must be a non-smoker who exercise no more than one time per week and have a BMI of 25-40
PI: Regensteiner, Judith
  • 303-724-2255
  • Deirdre.rafferty@ucdenver.edu
Persons with active, moderate to severe ulcerative colitis needed 12-1408
This study is being conducted to investigate the efficacy of methotrexate in treating ulcerative colitis in patients that have active, moderate to severe colitis and have failed other types of therapies.
Inclusion: Ages 18-70 Ulcerative colitis has been diagnoses by routine criteria At least one of the following applies: steroid dependent failed 5-ASA (mesalamine) therapy, such as Asacol Failed/lost response to infliximab (Remicade) Intolerant/unresponsive to azathioprine (Imuran) or 6-MP (purinethol) therapy Exclusion (partial): Existing pregnancy, lactation, or planned pregnancy (men and women)
PI: Gerich, Mark
  • 303-724-7875
  • katelyn.cowan@ucdenver.edu
Do you or someone you know have a food allergy to soy? 14-0097
We are studying the accuracy of a food allergy blood test.  
-Are age 1 to 21 and -Do have an IgE level greater than 0.35 to wheat OR soy or -Have had a positive skin test to wheat OR soy or -Have a clinically diagnosed wheat OR soy allergy -Do NOT use >500 micrograms/day fluticasone or equivalent -Do NOT have severe asthma, daily oral steroid dosing, or asthma requiring hospitalization within a year or an ER visit in the past 6 months -Do NOT have active EoE (or recently diagnosed) -Have NOT used biologic or allergen immunotherapy within the past year
PI: Fleischer, David
  • 720-777-2569
  • Hannah.Gilbert@childrenscolorado.org
Do you have HIV and lipodystrophy? 14-1595
Our research aims to determine whether the development of Lipodystrophy Syndrome is related to changes in the types of bacteria that live in the gut (stool) that occur in HIV-infected individuals.
Non-obese HIV-positive people who are 18-70 years old. Exhibiting the symptoms described above, indicating the possibility of lipodystrophy.
PI: Lozupone, PhD, Catherine
  • 303-724-0762
  • christine.griesmer@ucdenver.edu
Type 1 Diabetes Research Study 15-1309
The purpose of this research study is to evaluate the effects of an FDA-approved medication (bromocriptine QR) on insulin dosing, glucose control, and blood vessel function.
Persons 12-60 with Type 1 Diabetes, Non-smokers
PI: Schauer, Irene
  • 720-848-6690
  • ellen.lyon@ucdenver.edu
Healthy Adults Needed for Clinical Research Study 15-1643
The purpose of this study is to learn about the effects (good and bad) of interferon-gamma 1b (IFN-γ 1B) has on the body's immune cells when given to healthy adults.
Ages ≥ 18 to 60 years old Has not received IFN-γ within the last 30 days of study enrollment At the time of screening, deemed healthy by the Principal Investigator with no active infections and is not currently receiving medications for an infection No diagnosis of chronic health conditions or is on long-term medications for that condition Women of childbearing potential must have a negative pregnancy test to qualify and agree to two forms of effective contraception for the duration of the study (plus one month afterward)
PI: Ambruso, Daniel
  • 303-324-2171
  • daniel.ambruso@ucdenver.edu
Volunteers Needed for blood donation for research and development. WIRB 20110239
To gain knowledge relating to the collection, storage and product modifications of whole blood, apheresis units, and various blood components as well as the function and biochemistry of various types of blood cells.
YOU MAY QUALIFY TO DONATE IF YOU: -Are at least 18 years old -Weigh 110 pounds or more -Are in good general health -Can attend appointment(s) during the week
PI: Le, Tuan
  • 303-363-2202
  • Donor_Relations@bonfils.org
Have Pre-Diabetes? Do you want to lose weight and become more fit? 16-1404
Seeking volunteers for a research study testing muscle lipid metabolism and diabetes risk before and after a weight loss and exercise training intervention.
Men and women with pre-diabetes Age 30-50 Non-smoking Overweight (BMI 30-40) https://www.cdc.gov/healthyweight/assessing/bmi/adult_bmi/english_bmi_calculator/bmi_calculator.html
PI: Bergman, Bryan
  • 3037243968
  • anna.kerege@ucdenver.edu
The BURST Research Study 16-1769
This research study plans to learn more about how small frequent bouts of physical activity affects your health.
Healthy male and female Age: 19-45 With BMI: 25-35 Be seated more than 8hr/d Be physically active on less than 3 days/wk
PI: Bergouignan, Audrey
  • 303-724-9026
  • eats.study@ucdenver.edu
Research about the Effects of Your Genetics on the Contraceptive Implant (Nexplanon®) 16-2462
To research how genetic differences effect how well contraceptives work, specifically the contraceptive implant.
Are you a healthy woman between the ages of 18-45? Do you currently have the birth control implant (Nexplanon®) and have had it for the last 1 to 3 years?
PI: Aaron, Lazorwitz
  • 303-724-2013
  • rebecca.seale@ucdenver.edu
Are you pregnant? Are you in your last trimester of pregnancy? 16-2568
Research Subjects Needed to Participate in a Sleep Research Study in Pregnant Women
Women 32-34 weeks pregnant Age 20-39 years Singleton Pregnancy BMI >=30 NO Children under the age of 2 NO Diagnosed Sleep disorders DO NOT work the night shift NOT taking blood pressure medication NOT diagnosed with Gestational Diabetes
PI: Farabi, Sarah
  • 303-724-8534
  • sarah.farabi@ucdenver.edu
SPIROMICS-Subpopulations and Intermediate Outcome Measures in COPD Study HS-2678
To identify subpopulations of COPD patients in order to develop newer and more effective treatments and to clearly define measureable end points so that treatment effects may be accurately assessed in a shorter period of time.
Be willing to undergo study procedures Be between the age of 40 and 80 years old Have smoked fewer than one pack of cigarettes per day for one year OR have smoked more than one pack of cigarettes per day for 20 years
PI: Bowler, Russell
  • 303-270-2827
  • HerrudT@njHealth.org
A Study to Determine the Effectiveness of Seeing Dermatologist Online Compared to In-Person 14-0585
The purpose of the study is to see whether seeing a dermatologist online is just as effective as seeing one in-person. Help us determine whether online-based model is cost-saving and more efficient compared to face-to-face visits!
In order to qualify for the study, you must be 18 years or older and have psoriasis. You must have access to the internet, and a digital camera or a mobile phone with a camera.
PI: Dunnick, Cory
  • 720-848-3607
  • psoriasiscolorado@ucdenver.edu
Do You or Someone You Care for Suffer from Troublesome Drooling? 13-2237
A research study is being conducted to evaluate an investigational product for Sialorrhea (troublesome drooling).
You or your loved one may be eligible to participate if you meet the following criteria: 1. Have a diagnosis of Parkinson’s disease, adult cerebral palsy, ALS, stroke, traumatic brain injury, oral cancer, or side effects of medication, or any other condition that causes Sialorrhea or troublesome drooling 2. Have never received any type of treatment using Botulinum toxin type B 3. Have ability & availability to participate in a study for up to 1 year
PI: Klepitskaya, Olga
  • 303-724-4644
  • Nicola.haakonsen@ucdenver.edu
Parkinson's Disease Research Study 14-0879
clinical research study to look at the safety and effectiveness of an investigational medication, ADS-5102 (amantadine HCl) extended release capsules, for troublesome dyskinesia in subjects with Parkinson’s disease.
You may be eligible if you have Parkinson's Disease, currently take levodopa, and are experiencing troublesome dyskinesia (involuntary twisting and turning).
PI: Leehey, Maureen
  • 303-724-8305
  • Kalie.Petefish@ucdenver.edu
Type 2 Diabetes Medication Research Study 13-2015
Studying the effects of sitagliptin (a diabetes medication) on exercise capacity in people with type 2 diabetes
-Be a man or woman between 22 and 70 years old -Be generally healthy, with type 2 diabetes -Be taking metformin only for your diabetes -Be a non-smoker -Have a Body Mass Index greater than 25.0
PI: Regensteiner, Judith
  • 303-724-2255
  • Deirdre.rafferty@ucdenver.edu
" EDEN "Estrogen, Diabetes and Endothelial Function 10-0591
Study the effect of estrogen on blood vessels
CONTROL PARTICIPANT ELIGIBILITY · Age 18-45 · Premenopausal · Not using hormonal birth control currently or in the last 6 months (including oral contraceptives, contraceptive patch, Depo Provera, norplant, or IUD) · Not currently pregnant or planning to become pregnant in the next 3 months · No recent history of amenorrhea (no menstrual period for at least 3 months) during the last 6 months · Non-smoker · No antioxidant therapy (vitamin C or E or multivitamin) for at least 4 weeks prior to the first study visit   Normal thyroid function (can be treated)  T1D ELIGIBILITY  · Age 18-45 · Premenopausal · Have had type 1 diabetes for at least 5 years, were treated with insulin within a year of diagnosis, and are currently treated with insulin · Not using hormonal birth control currently or in the last 6 months (including oral contraceptives, contraceptive patch, Depo Provera, norplant, or  IUD) · Not currently pregnant or planning to become pregnant in the next 3 months · No recent history of amenorrhea (no menstrual period for at least 3 months) during the last 6months · Non-smoker · No antioxidant therapy (vitamin C or E or multivitamin) for at least 4 weeks prior to the first study visit  HbA1c < 9.5  Normal kidney function (urinary albumin excretion rate < 200 µg/min)         Normal thyroid function (can be treated)
PI: Snell-Bergeon, Janet
  • 303-724-6899
  • Caprice.sassano@ucdenver.edu
Volunteers needed for functional MRI research study 14-1282
Patients with schizophrenia are needed for a research study to learn more about how drugs used to treat illness symptoms affect weight gain and brain responses to food. We are also studying how exercise and diet affect these responses.
Diagnosis of schizophrenia/schizoaffective disorder; taking risperidone, olanzapine, or clozapine; capable of mild/moderate exercise; BMI less than 39; no heart problems or untreated high blood pressure; capable of MRI
PI: Tregellas, Jason
  • 303-724-8299
  • benjamin.lawful@ucdenver.edu
Attention Teens! Are You Concerned About Gaining Too Much Weight During Pregnancy? 14-1505
A research study at Children’s Hospital Colorado and Colorado State University seeks pregnant teenagers age 13-19y who may be at risk for gaining too much weight during pregnancy. Consider participating in this research study focused on testing a healthy pregnant weight gain program. The study involves 1 screening visit, 6 1-hour sessions during pregnancy or usual care, and follow-up visits within 3 months of having your baby. Eligible participants could be financially compensated up to $200-$250 for their time and inconvenience.
Female 13-19 years old Pregnant
PI: Sheeder, Jeanelle
  • 970-236-6317
  • bernadette.pivarunas@childrenscolorado.org
Physically active women and men needed for a research study on PTH and Calcium Responses to Exercise in Older Adults Experiment 2 (PACE Sr. 2) 15-0878
To determine if stopping the decrease in blood calcium during exercise impacts markers of calcium loss from the bone.
 A 60-80-year-old woman or man in generally good health  Often walk for exercise and can walk for an hour at a time  Not taking osteoporosis medication  No history of Diabetes or Cardiovascular Disease
PI: Wherry, Sarah
  • 720-848-6376
  • toby.wellington@ucdenver.edu
Parent Perspectives on Transitioning Premature Infants from Tube Feeding to Oral Feeding: Focus Group Research 16-0864
The purpose of this research study is to learn more about parent perspectives transitioning their premature infant from tube feeding to oral feeding.
Inclusion criteria: - Parent/caregiver of a child who was born prematurely (before 37 weeks) - Your child required tube feeding for at least the first three months of life - Your child is currently between 6 months and 5 years old Exclusion criteria: - Parent/caregiver is less than 18 years old
PI: Aldrich, Heather
  • 303-724-3363
  • heather.alrich@ucdenver.edu
Parkinson's disease: Do visual problems cause fatigue? 15-1714
Researchers from the University of Colorado Anschutz Medical Campus are conducting a study to investigate the relationship of eye movement and balance deficits with fatigue in people with Parkinson's disease.
Have clinically diagnosed idiopathic Parkinson's disease Are between 45 and 89 years old Are ale to walk independently without an assistive device
PI: Schenkman, Margaret
  • 303-724-7888
  • Jean.Berliner@ucdenver.edu
Research about the Effect of Isotretinoin (acne medication) on the Etonogestrel Contraceptive Implant (Implanon®/Nexplanon®) 16-0614
To research the effect of Isotretinoin, a medication used for severe acne, on the contraceptive implant.
Are you a healthy woman between the ages of 18-45? Are you currently under the care of a Dermatologist and considering starting treatment with isotretinoin (Accutane®)? Do you currently have the birth control implant (Implanon®/Nexplanon®) or are you planning to use the birth control implant during isotretinoin (Accutane®) therapy?
PI: Lazorwitz, Aaron
  • 303-724-2013
  • rebecca.seale@ucdenver.edu
Looking for HIV-positive & negative volunteers to participate in a research study on diet & gut microbiota 15-1692
This study plans to learn more about the short-term effects of consuming either a Western style diet or Agrarian-style diet (A diet low in fat and high in fiber/carbohydrates) on inflammation in people with and without HIV.
We are seeking men and women volunteers who are:  Between the ages of 18 and 65  Have a BMI between 21-29 mg/kg2 and weight stable for past 3 months  Willing to follow assigned diet for 4 weeks  If HIV-positive, treated with ART for at least 12 months--no changes in drugs over past 6 months, and plasma HIV-1 RNA ≤50 copies/mL for past 6 months
PI: Lozupone, Catherine
  • 303-724-0762
  • Christine.Griesmer@ucdenver.edu
Contraceptive Clinical Trial for healthy women 18-40 17-0225
Contraceptive clinical trial looking at two non-hormonal copper intrauterine devices (IUD), one of which is investigational.
Healthy women 18-40 Regular menstrual cycles Sexually active
PI: Teal, Stephanie
  • 303 724 5559
  • ines.crato@ucdenver.edu
We are looking for Healthy Women to participate in a research study on.....Females, Aging, Metabolism, and Exercise (FAME) 12-1157
To examine the role that female sex hormones play in metabolism, energy expenditure, physical activity and chronic disease.
Healthy women 40-60 who have regular menstrual cycles and using no hormonal contraceptives
PI: Kohrt, Wendy
  • 720-848-6399
  • FAMEStudy@ucdenver.edu
Do you have Diabetes? 13-0131
To find the best combination drug treatment for type 2 diabetes
Persons who have had diabetes for less than 5 years and metformin is the only diabetes medication you are taking.
PI: Rasouli, Neda
  • 720-848-7174
  • Stephanie.Steiner@ucdenver.edu
Type 1 Diabetes Research Study 11-0693
To study the effects of an FDA-approved medication on metabolism and blood vessel function.
Person 25-50 with type 1 diabetes who exercise vigorously less than four times per week and have normal blood pressure
PI: Schauer, Irene
  • 720-848-6690
  • Ellen.Lyon@ucdenver.edu
Just received VARIVAX, the chickenpox vaccine? 13-2122
Research study looking at the immune response to chickenpox vaccine
Age 12 months to 50 years; able to enroll in study within 10 days of vaccination.
PI: Levin, Myron
  • 303-724-2454
  • nancy.lang@ucdenver.edu
Looking for HIV-positive individuals to participate in a research study on Lipodystrophy Syndrome 14-1595
We are conducting a study of the relationship of bacteria in the gut to HIV infection. We are interested in finding out whether people who have metabolic diseases such as lipodystrophy (loss of fat tissue) as complications of long term antiretroviral therapy have a different makeup of their gut bacteria. We are therefore seeking volunteers with HIV infection to participate in a study of bacteria in the stool.
-Non-obese HIV positive individuals who are 18-65 years old -Either not currently on antiretroviral therapy (ART naïve or off therapy for 6 months or greater) or on effective ART with documented suppression for 6 months or greater. -We are particularly interested in enrolling subjects with lipodystrophy, but would also like to enroll individuals without lipodystrophy as controls.
PI: Lozupone, PhD, Catherine
  • 303-724-0762
  • christine.griesmer@ucdenver.edu
Looking for HIV-positive and HIV-negative men to participate in a research study on smoking and lung disease 13-2986
We are conducting a study to look at lung complications and disease in HIV/AIDS.
-Between 30 and 70 years old -Both HIV-positive and HIV-negative individuals with and without chronic obstructive pulmonary disease (COPD) -If HIV-positive, on a stable three-drug ART regimen with undetectable viral load for past 6 months
PI: Campbell, MD, Thomas
  • 303-724-0762
  • christine.griesmer@ucdenver.edu
GENETIC-AF 14-0736
The GENETIC-AF is a trial that will investigate the safety and effectiveness of an investigational drug on the recurrence of symptomatic atrial fibrillation in people who have heart failure. The investigational drug will be studied versus an approved drug after patients receive an electrical cardioversion.
Adults who have symptomatic atrial fibrillation may be eligible.
PI: Aleong, Ryan
  • 303-724-8277
  • Christina.schmitt@ucdenver.edu
Information for patients. Living with diabetes is complicated. 15-2154
The FREEDOM-3S Study is a clinical research study that will involve approximately 126 patients in the United States. It will look at a potential new treatment option, the ITCA 650,for people with type 2 diabetes. The ITCA 650 is a small metal cylinder (about the size of a matchstick) that is placed under the skin of the abdomen (belly) to slowly release the study medication – exenatide. The FREEDOM-3S Study is looking at how safe and well tolerated two different doses of the ITCA 650 are in people with type 2 diabetes who are already taking liraglutide (also known as Victoza injections, and metformin.
You may be eligible to take part if you: • are 18–80 years of age • have been diagnosed with type 2 diabetes for at least 3 months • have been taking liraglutide (Victoza) injections and metformin every day for at least 3 months.
PI: Rasouli, Neda
  • 720-848-5596
  • Hoda.Farajpour@ucdenver.edu
Controlling blood glucose levels. Can be a real balancing act. 15-1439
The EASE-3 clinical research study is a study in which doctors hope to learn: • Whether the investigational medicine is safe to use in treating type 1 diabetes. • Whether adding the investigational medicine is more effective in controlling blood glucose than insulin alone.
You may be able to join this study if you: • Are 18 years of age or older and you have had insulin-dependent type 1 diabetes for at least a year. • Are willing to take a study medicine in addition to your insulin therapy. • Have an HbA1c level that falls within the range required by the study. • Have a good understanding of your disease and the ability to manage it and are willing to undergo study assessments.
PI: Rasouli, Neda
  • 720-848-1852
  • Yusra.Azhar@ucdenver.edu
Do you have headaches? 15-0983
The University of Colorado is participating in a research study to determine if thoracic spine thrust manipulation alone is beneficial in the treatment of cervicogenic headaches. This project will see if this treatment can aid in reducing pain from these headaches.
You may be eligible to participate in this study if you answer yes to the following questions: - Do you have headaches that are mostly on one side which are associated with neck pain? - Are these headaches worse with movement or certain neck positions? - Do you have these headaches at least once a week for at least the last 2 months? - Are you between 18-60 years of age? - Can you come to physical therapy up to 6 times within a 30 day period? You may be ineligible to participate in this study if you have: - Rheumatoid arthritis - Osteoporosis - Broken bones in your neck or shoulder - A prolonged history of steroid use - A history of whiplash injury within the past six weeks
PI: McDevitt , Amy
  • 3037241906
  • amy.mcdevitt@ucdenver.edu
Rotator Cuff Clinical Research Study 15-1348
The InSpace device is a balloon shaped implant made from a polymer, which is widely used material in the medical industry. The material is biodegradable meaning that following surgery it will gradually dissolve until it is completely absorbed at approximately one year following the implantation. During this time, the device is intended to support your shoulder healing allowing frictionless gliding between the shoulder bones which may improve shoulder muscle activity.
In order to participate, you must: Be 40 years of age or over and in general good health. Experiencing persisting shoulder pain for at least four (4) months which failed non-operative treatments such as: • Physical therapy • Activity modification • Rest (sling) • Anti-inflammatory medication Have had an MRI within 9 months that confirms a full thickness rotator cuff tear. Fulfill all study criteria as assessed by your surgeon and be willing to return for all follow-up visits.
PI: Bravman, Jonathan
  • 303-315-9925
  • jessie.larson@ucdenver.edu
Participants needed for an RSV Vaccine Study 16-2752
We are looking for participants for a research study to test a vaccine to prevent Respiratory Syncytial Virus (RSV) in infants and children. Your child can participate if he/she has a healthy immune system and has never had an infection or illness caused by RSV.
- 6 months to 24 months of age -not in daycare with other children 6 months or younger
PI: McFaland, Betsy
  • 720-777-3294
  • chipresearch@childrenscolorado.org
EFFECTS OF TESTOSTERONE THERAPY IN YOUNG ADOLESCENTS WITH KLINEFELTER SNDROME (47.XXY) 11-0874
This study will study the effects of testosterone therapy on behavior, mood, problem solving, attention span, and motor skills in adolescent males with Klinefelter syndrome in early puberty. During this period in early puberty there is a lot of variability in how and when doctors start testosterone therapy. This study will evaluate if there are benefits to starting testosterone therapy in early puberty.
Participants with Klinefelter syndrome in early puberty (around age 10-15).
PI: Tartaglia, Nicole
  • 720-777-8361
  • susan.howell@childrenscolorado.org
Volunteers with Alzheimer’s Disease Needed for Memory Study 12-1273
To examine the safety and efficacy of the study drug, Sargramostim (Leukine®), on memory in adults with Mild-to-Moderate Alzheimer’s Disease.
1. Age 55 to 85 years; 2. Should have a mild-to-moderate Alzheimer's Disease diagnosis (Mini-Mental State Examination 10-26 inclusive); 3. If on anti-dementia treatment should be on stable treatment for at least 2 months (i.e. cholinesterase inhibitor and/or Memantine or Axona); 4. Stable on all other medications for at least 30 days prior to screen; 5. Should be fluent in English; 6. Should be physically able to participate by medical history, clinical exam and tests; 7. Should have a study partner to accompany them to scheduled visits.
PI: Potter, Huntington
  • 303-724-2997
  • joseph.daniels@ucdenver.edu
T•A•C•I•T - Therapy After Cochlear Implants Using Telemedicine 12-1103
This research plans to learn more about the use of telemedicine as a means of providing therapy to children who have a cochlear implant(s). While Auditory-Verbal Therapy has typically been delivered in person, many people are starting to access therapy over the internet. We are conducting this research to determine if the outcomes of therapy are the same when AVT is delivered in person and via telemedicine.
The TA•C•I•T team is looking for children ages 6 mos.-6 yrs. old who were implanted with cochlear implant(s) before age  3 ½..  Each child will spend nine months in both the in-person and telemedicine condition. The therapist will remain the same throughout the study. Total participation will last 18 months. The child will be tested three times: once when the study starts, and every nine months after that. A qualified study team member will administer speech, listening, and language tests to the child. They will also receive tests to identify how well their auditory area of the brain is developing.
PI: Grigsby, Jim
  • 303-556-5804
  • tacit@ucdenver.edu
Participants with Chronic Kidney Disease Needed for a Research Study about Phosphate 13-0328
We are looking for men and women to participate in a research study examining whether lowering blood levels of phosphate will improve blood vessel function.
We need men and women who:  -are age 40-79 years old; women must be post-menopausal;  -have chronic kidney disease stage 3b or 4 (estimated GFR 15-45 ml/min);  -are not taking phosphate binders;  -do not have high blood phosphate (>5.5 mg/dL).
PI: Jovanovich, Anna
  • 303-724-7790
  • mikaela.malaczewski@ucdenver.edu
Volunteers Needed for Cardiovascular Research Study at the Division of Renal Diseases and Hypertension Clinical Research Unit 15-0869
This research study will compare blood vessel function in healthy adults to adults with two different types of kidney disease. The testing visit will include non-invasive testing of blood vessel function and collection of blood and cells from an IV.  As a volunteer, you will receive the following information about your health: resting EKG; blood cholesterol screening,    blood sugar screening, blood pressure screening, and physical Exam.
We are looking for men and women, aged 50-80 years, non-smokers, generally healthy, and free from hypertension.  Women must not be pregnant of trying to become pregnant
PI: Nowak, Kristen
  • 303-724-7793
  • Mikaela.Malaczewski@ucdenver.edu
Healthy Women Needed 15-1052
This study plans to research how metabolic challenges of increased insulin and increased fats affect reproductive hormones.
In order to be eligible you must: Be a healthy woman age 18-38, have a BMI between 18 and 25, have regular menstrual cycles (25-35 days), not be currently using hormones (like birth control medication), not be pregnant or planning to become pregnant. In order to enroll all participants must meet specific criteria. The criteria listed above is only a partial list of all the requirements. Only a clinical research staff member can determine eligibility.
PI: Santoro, Nanette
  • 303-724-5276
  • sarah.black@ucdenver.edu
Does outpatient palliative care improve patient-centered outcomes in Parkinson's disease? 15-0814
This study plans to learn more about the effect of palliative care on patients and caregivers affected by Parkinson’s disease or related disorders including progressive supranuclear palsy (PSP), corticobasal degeneration (CBD), multiple system atrophy (MSA) or Lewy Body Dementia (LBD). Palliative care is a treatment approach focused on improving quality of life by relieving suffering in the areas of physical symptoms such as pain, psychiatric symptoms such as depression, psychosocial issues and spiritual needs.
Over the age of 40 and have been diagnosed with Parkinson's disease (PD), progressive supranuclear palsy (PSP), corticobasal degeneration (CBD), multiple system atrophy (MSA), or Lewy Body Dementia (LBD); and have unmet needs, such as poorly controlled non-motor symptoms, psychological issues, spiritual challenges or caregiver distress.
PI: Kluger, Benzi
  • 303-724-4718
  • Etta.Abaca@ucdenver.edu
Volunteers Needed for a Research Study about Rheumatoid Arthritis 15-2280
The purpose of this study is to learn more about how rheumatoid arthritis develops even before the first joint symptoms appear.
You may be able to participate in the study if: You are at least 18 years old You do NOT have rheumatoid arthritis (RA)
PI: Deane, MD/PhD, Kevin
  • 303-724-1129
  • TIP-RA@ucdenver.edu
Heart Sounds at Home: Prospective Maternal Surveillance of SSA Positive Pregnancies using a Hand-held Fetal Heart Rate Monitor 13-1879
The purpose of the research study is for pregnant SSA positive mothers, using a home Doppler fetal heart rate monitor, to detect abnormal heart rates and rhythms in their babies before they are both
Exclusion criteria are: 1. If you are less than 16 weeks or > 18 6/7 th weeks pregnant 2. If you do not have SSA antibodies
PI: Cuneo, Bettina
  • 720-777-9514
  • Halley.Isberg@childrenscolorado.org
Smokers Wanted for Brain Research Study 15-1016
We want to know if magnetic stimulation of the brain can reduce cigarette cravings. We will do an MRI of your brain before and after the magnetic stimulation. This study takes 3 hours of your time in one single visit. We want to know if transcranial magnetic stimulation of the brain can reduce cigarette cravings. We will do an MRI of your brain before and after the magnetic stimulation. This study takes 3 hours of your time in one single visit. This study is funded by the NIH (F32 DA 041011).
You may qualify if you: • Smoke at least 10 cigarettes per day (on average) • Are 18-55 years old • Have no metal implants • Have no history of seizures • Are able to not smoke for 3 hours
PI: Regner, Michael
  • 414-397-3878
  • michael.regner@ucdenver.edu
Are you interested in learning about how your breast milk helps your baby grow? 12-0629
To find out how maternal size and diabetes status affect her breast milk To find out what unique parts of breast milk may affect how infants grow. To learn how to ensure infants receive the best nutrition possible
Women 20-35 with type 1, type 2,or gestational diabetes who are at least 28 weeks into their pregnancy and planning on exclusively breastfeeding their infant for at least 4 months and delivering at University of Colorado Hospital.
PI: Krebs, Nancy
  • 303-724-8966
  • Nicole.Hirsch@ucdenver.edu
Free Family Therapy for Youth with Mood Problems 11-1048
Helping youth and their families understand and cope with mood swings, develop plans for preventing moods from getting worse, communicate more effectively and solve family problems
  • Youth between 9-17 who has recently had significant mood swings, has at least one parent with bipolar disorder and does not abuse alcohol or substances. 
  • Must agree not to participate in family therapy with another provider for the first year.
PI: Schneck, Christopher
  • 303-492-1668
  • Anna.Frye@colorado.edu
Genital Herpes? 13-2122
This study will look at the body's immune response (how the body fights infection) to the onset of genital herpes.  1-2 study visits for blood draws over the course of 3 months.
  • 18+ years of age
  • Have developed an outbreak of genital herpes within the last 10 days.
PI: Levin, Myron
  • 303-724-2454
  • nancy.lang@ucdenver.edu
Healthy Males needed for a research study of drug levels in blood and hair. 13-0427
This study plans to learn more about how tenofovir and emtricitabine (Truvada) build up in cells in blood and hair. Participation will include two 12 week dosing periods separated by a 12 week washout period (total duration is 36 weeks). Eligible participants will be given the supply of medications for the study.
  • Must be age 18 to 50 years
  • Must own smartphone
  • Subject has a minimum scalp hair length of 2 cm in the occipital region.
  • Have a low risk for HIV-1 infection
PI: Anderson, Peter
  • 303-724-8296
  • kayla.bushman@ucdenver.edu
The Role of Gut Bacteria in the Development of Type 1 Diabetes. 11-1144
The goal of the research is to better understand the role bacteria that live in the intestine in the development of type 1 diabetes
  • Patients diagnosed with type 1 diabetes in the last 6 months 
  • Subjects with islet autoantibodies 
  • Subjects who do not have islet antibodies and are first-degree relatives of patients with diabetes or subjects with islet antibodies
  • 1-45 years of age
PI: Zipris, Danny
  • 303-724-6820 or 303-724-6821
  • aimon.alkanani@ucdenver.edu or james.needell@ucdenver.edu
Are you interested in participating in a research study to help us learn more about where the fat tissue in your body originates? 13-0026
To understand if some fat cells (adipocytes) may originally come from cells in the bone marrow. Understanding the origin of fat cells is important because it may help to determine the health of fat cells and why fat that is stored in some places of your body is more ‘unhealthy’ than other fat.
Men and women: Between the ages of 18 and 75 years AND Had an allogeneic hematopoietic stem cell transplant at least 6 months ago –OR– Have chronic phase chronic myeloid leukemia.
PI: Klemm, Dwight
  • 303-724-7472
  • kathleen.gavin@ucdenver.edu
Are you looking for an alternative treatment for your insomnia? HS-2891
The purpose of this pilot study is to learn more about treatments for insomnia. Long-term use and dependence on controlled substance sleep medications (also known as “hypnotics”) is a common issue and is a less than ideal way to treat insomnia. Stopping the use of sleeping pills and trying other treatments for insomnia is difficult for many insomnia patients. Treatments combining supervised medication tapering (SMT), which is a gradual reduction of medication use, and cognitive behavioral insomnia therapy for insomnia (CBT-I), which is a form of talk therapy that helps a person learn to better handle behaviors, habits and thoughts that lead to sleeping problems., help some who wish to stop using sleep aids, but many individuals who complete these treatments do not give up their sleep aids altogether. This project will look at how to best help insomnia patients transitioning from using sleep aids to other treatment options for their insomnia.
• Adults 21 years of age and older who have chronic insomnia • Current medication use for treatment of chronic insomnia (over one year) • Desire to stop medication use
PI: Wamboldt, Fred
  • 303-270-2850
  • BurlesonA@NJHealth.org
Participants needed for a study with Diabetes and couples health behaviors 15-0601
This is a couples-based approach for increasing physical activity among adults with type 2 diabetes. Increasing physical activity has been shown to have great health benefits for managing diabetes.
One partner (or both) has Type 2 Diabetes One partner (or both) has been sedentary Each member is willing to increase their current level of physical activity Between the ages of 30 and 69
PI: Wooldridge, Jennalee
  • 720-372-3856
  • healthycoupleslab@gmail.com
Healthy men needed for cardiovascular study 15-1162
The purpose of this research is to study how low testosterone affects the health of the heart and arteries in men.
- Men  50-75 years old, in general good health - No history of cancer, diabetes or heart disease - Non-smokers - Not currently taking medications to treat high blood pressure, cholesterol, taking testosterone therapy or exercising vigorously more than 2 days per week
PI: Moreau, Kerrie
  • (303) 724-2253
  • cardiovolt.study@ucdenver.edu
Role of Bacterial Toxins in Atopic Dermatitis HS-1962
To investigate inflammation in the skin of subjects with psoriasis and how this is different from subjects with Atopic Dermatitis
12 years or older and have a history of psoriasis
PI: Leung, Donald
  • 303-398-1409
  • bronchickc@njhealth.org
Are you at risk for type 2 diabetes ? 14-2402
Physicians at 23 sites across the United States are conducting a research study in adults at risk for diabetes to see whether daily vitamin D supplementation can delay the onset of diabetes. Understanding whether vitamin D has an effect on glucose (sugar) metabolism may lead to new treatments for diabetes. According to the Centers for Disease Control and Prevention, about 80 million people are at risk for developing diabetes. Persons who are older than 45 years of age, are overweight, have a family member with diabetes, have high blood pressure, or who do not get enough exercise are at risk for type 2 diabetes. Women who had diabetes during pregnancy and people from certain ethnicities are also at risk.
Men or women older than 30 years who are at risk for diabetes. You must agree not to take nutritional supplements or other preparations during the study containing vitamin D in excess of 1000 units per day or calcium in excess of 600 mg per day from all sources combined. Persons with diagnosed diabetes, kidney stones or kidney disease are not eligible. Other exclusions also apply.
PI: Rasouli, Neda
  • 720-848-1816
  • Abtin.Kiany@ucdenver.edu
Participants ages 7-65 undergoing upper endoscopy needed for Research Study 07-0223
Determine the efficacy of the EnteroTracker String Test (EST)for monitoring inflammation in the esophagus. Compare analysis of the EST to biopsies taken during an upper endoscopy.
Diagnosed EOE or patients with symptoms of abdominal pain, vomiting, growth delay or malabsorption with an Upper Endoscopy scheduled at either Children’s Hospital Colorado or the University of Colorado Hospital. Other Exclusion criteria may apply.
PI: Furuta, Glenn
  • 720-777-2797
  • Faria.Ahmed@childrenscolorado.org
Volunteers wanted for Asthma Research Study 16-2041
Researchers at the University of Colorado is seeking volunteers for an asthma research study to learn how weight and dietary supplement typically found in watermelon (Citrulline) may relate to asthma.
You may be eligible to participate if you:  Are between the ages of 18 and 60 years old  Have been diagnosed with asthma by a healthcare provider  Are overweight (a body mass index of 30 or greater)  Are not pregnant, breastfeeding, or planning to get pregnant in the next 6 months  Do not currently smoke  Have not smoked more than 1 pack a day over the last 10 years
PI: Holguin, Fernando
  • 3037240325
  • vongphone.smith@ucdenver.edu
Breast Cancer. Genetic Testing and Health Insurance: A Research Study 16-660
The goal of this research study is to understand how breast cancer patients in Colorado are able to obtain genetic testing and how test results are used to make treatment decisions. We are interested in talking with all breast cancer patients and survivors diagnosed in Colorado
Are you a breast cancer patient or survivor? Were you diagnosed in 2009 or after? Were you diagnosed in Colorado? If you answered “YES” to all three questions, you are eligible. You do NOT have to have received genetic testing to be in this study!
PI: Hammad, Emily
  • 303-915-2510
  • emily.hammad@ucdenver.edu
Research on a new group intervention for pediatric autonomic dysfunction. 17-0470
This research aims to evaluate a new group therapy intervention for youth with autonomic dysfunction and their parents.
Eligible families will have a teenager who is between 13 and 18 years old, has a diagnosis of autonomic dysfunction, dysautonomia, orthostatic intolerance, and/or POTS (postural orthostatic tachycardia syndrome), and has difficulty completing day-to-day activities like going to school, and/or has been experiencing anxiety or worries and/or low mood.
PI: Malmberg, Jessica
  • 720 777-4169
  • clio.pitula@childrenscolorado.org