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Clinical Trials

Volunteer to Be Part of a Research Study

Page through all School of Medicine clinical and research trials below. There are two categories:

  • Detailed Trial Descriptions, submitted by researchers, includes trial specifics and contact information.

  • Additional Clinical Trials, which include basic study details. To contact the researcher either Google the PI (primary investigator) name or use our campus directory.

If you are a researcher seeking volunteers and your study is not posted, please
submit your Web ad here.
  

Detailed Trial Descriptions

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COMIRB Approved Advertisement TitleStudy GoalsEligibility CriteriaDate PostedCategory
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Diabetic Male and Female Volunteers Needed for Exercise Research Study
Evaluate exercise function during single leg calf exercise in people with or without type 2 diabetes
Healthy Adults 30-70 with Type 2 diabetes but not using insulin. Must be a non-smoker who exercise no more than one time per week and have a BMI of 25-40
7/1/2016 
Persons with active, moderate to severe ulcerative colitis needed
This study is being conducted to investigate the efficacy of methotrexate in treating ulcerative colitis in patients that have active, moderate to severe colitis and have failed other types of therapies.
Inclusion: Ages 18-70 Ulcerative colitis has been diagnoses by routine criteria At least one of the following applies: steroid dependent failed 5-ASA (mesalamine) therapy, such as Asacol Failed/lost response to infliximab (Remicade) Intolerant/unresponsive to azathioprine (Imuran) or 6-MP (purinethol) therapy Exclusion (partial): Existing pregnancy, lactation, or planned pregnancy (men and women)
7/1/2016 
Have the Flu? Living with a chronic medical condition, too?
Influenza (the flu) can be life-threatening. Approximately 24,000 people in the United States die each year of this disease. We are conducting a study to determine whether treating patients with a combination of several drugs instead of just one helps them to get better faster.
You qualify for our study if you: •Have been diagnosed with the flu •Are at least 18 years of age •Have an existing medical condition that puts you at increased risk for complications from the flu—conditions such as diabetes; heart, lung, and kidney disease; COPD; and asthma
7/1/2016 
Do you or someone you know have a food allergy to soy?
We are studying the accuracy of a food allergy blood test.  
-Are age 1 to 21 and -Do have an IgE level greater than 0.35 to wheat OR soy or -Have had a positive skin test to wheat OR soy or -Have a clinically diagnosed wheat OR soy allergy -Do NOT use >500 micrograms/day fluticasone or equivalent -Do NOT have severe asthma, daily oral steroid dosing, or asthma requiring hospitalization within a year or an ER visit in the past 6 months -Do NOT have active EoE (or recently diagnosed) -Have NOT used biologic or allergen immunotherapy within the past year
7/1/2016 
Participants Needed For Research on Military Veterans And Service Dogs
The purpose of this study is to explore the relationship between military veterans and their service dogs. Veterans will participate in one on one interviews.
Are you a military veteran? Do you have a service dog? Are you 18-89 years old? If you answered yes to the above, contact C-P.A.W.W. today.
7/1/2016 
Do you have HIV and lipodystrophy?
Our research aims to determine whether the development of Lipodystrophy Syndrome is related to changes in the types of bacteria that live in the gut (stool) that occur in HIV-infected individuals.
Non-obese HIV-positive people who are 18-70 years old. Exhibiting the symptoms described above, indicating the possibility of lipodystrophy.
7/1/2016Immune System Diseases
Type 1 Diabetes Research Study
The purpose of this research study is to evaluate the effects of an FDA-approved medication (bromocriptine QR) on insulin dosing, glucose control, and blood vessel function.
Persons 18-60 with Type 1 Diabetes, Non-smokers
7/1/2016Nutritional and Metabolic Diseases
We are looking for MEN who have not been diagnosed with cancer to participate in a research study.
A comparison of immune function from unaffected individuals for the study of tumor-induced immune suppression
To participate you must: -Older than 18 -Be willing to make a one-time blood donation -Not be diagnosed with an immune disease such as diabetes, hepatitis or rheumatoid arthritis You could make a difference in the future of men!
7/1/2016Cancers and Other Neoplasms
Participants needed for a Balance and Fall-Risk Research Study for People with Multiple Sclerosis
This study involves balance and head movement testing aimed at predicting risk of falls
Are between the ages of 30 and 60 years
• have MS
• are able to turn your head at least 30 degrees to the left,
• have experienced a fall in the last 3 months
7/1/2016Nervous System Diseases
Healthy Adults Needed for Clinical Research Study
The purpose of this study is to learn about the effects (good and bad) of interferon-gamma 1b (IFN-γ 1B) has on the body's immune cells when given to healthy adults.
Ages ≥ 18 to 60 years old Has not received IFN-γ within the last 30 days of study enrollment At the time of screening, deemed healthy by the Principal Investigator with no active infections and is not currently receiving medications for an infection No diagnosis of chronic health conditions or is on long-term medications for that condition Women of childbearing potential must have a negative pregnancy test to qualify and agree to two forms of effective contraception for the duration of the study (plus one month afterward)
7/1/2016--Select a Category--
Volunteers Needed for blood donation for research and development.
To gain knowledge relating to the collection, storage and product modifications of whole blood, apheresis units, and various blood components as well as the function and biochemistry of various types of blood cells.
YOU MAY QUALIFY TO DONATE IF YOU: -Are at least 18 years old -Weigh 110 pounds or more -Are in good general health -Can attend appointment(s) during the week
7/1/2016Blood and Lymph Conditions
Apoyo con Cariño: Improving Palliative Care for Latinos with Cancer
We want to understand if a patient navigator can help Latino patients and their family caregivers deal with cancer. Our project hopes to improve palliative or comfort care to patients with advanced cancer. The goal is to prevent or relieve suffering for people facing serious illness. Research is needed to find out if a patient navigator can help patients and family caregivers.
Adults (18 years and older) who self-identify as Latino and have Stage III-IV cancer.
6/30/2016 
SPIROMICS-Subpopulations and Intermediate Outcome Measures in COPD Study
To identify subpopulations of COPD patients in order to develop newer and more effective treatments and to clearly define measureable end points so that treatment effects may be accurately assessed in a shorter period of time.
Be willing to undergo study procedures Be between the age of 40 and 80 years old Have smoked fewer than one pack of cigarettes per day for one year OR have smoked more than one pack of cigarettes per day for 20 years
6/30/2016 
Healthy Female Adolescents Needed!!!
For brain imaging research study on how the brain works with we taste sweets or receive money. Your participation could help us to develop treatments and preventive measures for anorexia nervosa and obesity
Healthy females 11 to 21 who are right-handed, free of medication with no serious medical conditions, permanent metal implants or braces/retainers, and are at a healthy body weight.
6/30/2016 
A Study to Determine the Effectiveness of Seeing Dermatologist Online Compared to In-Person
The purpose of the study is to see whether seeing a dermatologist online is just as effective as seeing one in-person. Help us determine whether online-based model is cost-saving and more efficient compared to face-to-face visits!
In order to qualify for the study, you must be 18 years or older and have psoriasis. You must have access to the internet, and a digital camera or a mobile phone with a camera.
6/30/2016 
Do You or Someone You Care for Suffer from Troublesome Drooling?
A research study is being conducted to evaluate an investigational product for Sialorrhea (troublesome drooling).
You or your loved one may be eligible to participate if you meet the following criteria: 1. Have a diagnosis of Parkinson’s disease, adult cerebral palsy, ALS, stroke, traumatic brain injury, oral cancer, or side effects of medication, or any other condition that causes Sialorrhea or troublesome drooling 2. Have never received any type of treatment using Botulinum toxin type B 3. Have ability & availability to participate in a study for up to 1 year
6/30/2016 
Parkinson's Disease Research Study
clinical research study to look at the safety and effectiveness of an investigational medication, ADS-5102 (amantadine HCl) extended release capsules, for troublesome dyskinesia in subjects with Parkinson’s disease.
You may be eligible if you have Parkinson's Disease, currently take levodopa, and are experiencing troublesome dyskinesia (involuntary twisting and turning).
6/30/2016 
Type 2 Diabetes Medication Research Study
Studying the effects of sitagliptin (a diabetes medication) on exercise capacity in people with type 2 diabetes
-Be a man or woman between 22 and 70 years old -Be generally healthy, with type 2 diabetes -Be taking metformin only for your diabetes -Be a non-smoker -Have a Body Mass Index greater than 25.0
6/30/2016Nutritional and Metabolic Diseases
Research study to investigate how therapies work to reduce tension-type headache
To understand how massage or ultrasound therapies affect blood flow within myofascial trigger points that are related to chronic pain such as tension-type headache.
Persons aged 21-49 who experience chronic or episodic tension-type headache and are not currently receiving massage, ultrasound, trigger point injection, or needling therapies.
6/30/2016Muscle, Bone, and Cartilage Diseases
" EDEN "Estrogen, Diabetes and Endothelial Function
Study the effect of estrogen on blood vessels
CONTROL PARTICIPANT ELIGIBILITY · Age 18-45 · Premenopausal · Not using hormonal birth control currently or in the last 6 months (including oral contraceptives, contraceptive patch, Depo Provera, norplant, or IUD) · Not currently pregnant or planning to become pregnant in the next 3 months · No recent history of amenorrhea (no menstrual period for at least 3 months) during the last 6 months · Non-smoker · No antioxidant therapy (vitamin C or E or multivitamin) for at least 4 weeks prior to the first study visit   Normal thyroid function (can be treated)  T1D ELIGIBILITY  · Age 18-45 · Premenopausal · Have had type 1 diabetes for at least 5 years, were treated with insulin within a year of diagnosis, and are currently treated with insulin · Not using hormonal birth control currently or in the last 6 months (including oral contraceptives, contraceptive patch, Depo Provera, norplant, or  IUD) · Not currently pregnant or planning to become pregnant in the next 3 months · No recent history of amenorrhea (no menstrual period for at least 3 months) during the last 6months · Non-smoker · No antioxidant therapy (vitamin C or E or multivitamin) for at least 4 weeks prior to the first study visit  HbA1c < 9.5  Normal kidney function (urinary albumin excretion rate < 200 µg/min)         Normal thyroid function (can be treated)
6/30/2016Heart and Blood Diseases
Rhythmic Enhancement of Motor Performance
It is known that people with Parkinson's Disease are able to move better with music or rhythm. This research study plans to learn more about he areas of the brain that react to rhythm in people with Parkinson's Disease (PD) and healthy older adults.
Healthy male older controls aged 55-85.
6/30/2016Nervous System Diseases
Volunteers needed for functional MRI research study
Patients with schizophrenia are needed for a research study to learn more about how drugs used to treat illness symptoms affect weight gain and brain responses to food. We are also studying how exercise and diet affect these responses.
Diagnosis of schizophrenia/schizoaffective disorder; taking risperidone, olanzapine, or clozapine; capable of mild/moderate exercise; BMI less than 39; no heart problems or untreated high blood pressure; capable of MRI
6/30/2016Behaviors and Mental Disorders
We are looking for Healthy Women to participate in a research study on.....Females, Aging, Metabolism, and Exercise (FAME)
To examine the role that female sex hormones play in metabolism, energy expenditure, physical activity and chronic disease.
Healthy women 40-60 who have regular menstrual cycles and using no hormonal contraceptives
6/29/2016 
Do you have Diabetes?
To find the best combination drug treatment for type 2 diabetes
Persons who have had diabetes for less than 5 years and metformin is the only diabetes medication you are taking.
6/29/2016 
Type 1 Diabetes Research Study
To study the effects of an FDA-approved medication on metabolism and blood vessel function.
Person 25-50 with type 1 diabetes who exercise vigorously less than four times per week and have normal blood pressure
6/29/2016 
CHILDHOOD and ADOLESCENT MIGRAINE PREVENTION STUDY
to test two medicines for migraine prevention in children and teens. We want to see if amitriptyline and/or topiramate are better than placebo (sugar pill) in reducing headache frequency.
Children 8-17 who have migraine headaches
6/29/2016 
Just received VARIVAX, the chickenpox vaccine?
Research study looking at the immune response to chickenpox vaccine
Age 12 months to 50 years; able to enroll in study within 10 days of vaccination.
6/29/2016 
Healthy Hispanic Female Needed
For brain imaging research study on how the brain works with we taste sweets. Your participation could help us to develop treatments and preventive measures for anorexia nervosa and obesity
Healthy females 22 to 29 who are right-handed, free of medication with no serious medical conditions, permanent metal implants or braces/retainers, and are at a healthy body weight.
6/29/2016 
Looking for HIV-positive individuals to participate in a research study on Lipodystrophy Syndrome
We are conducting a study of the relationship of bacteria in the gut to HIV infection. We are interested in finding out whether people who have metabolic diseases such as lipodystrophy (loss of fat tissue) as complications of long term antiretroviral therapy have a different makeup of their gut bacteria. We are therefore seeking volunteers with HIV infection to participate in a study of bacteria in the stool.
-Non-obese HIV positive individuals who are 18-65 years old -Either not currently on antiretroviral therapy (ART naïve or off therapy for 6 months or greater) or on effective ART with documented suppression for 6 months or greater. -We are particularly interested in enrolling subjects with lipodystrophy, but would also like to enroll individuals without lipodystrophy as controls.
6/29/2016 
Looking for HIV-positive and HIV-negative men to participate in a research study on smoking and lung disease
We are conducting a study to look at lung complications and disease in HIV/AIDS.
-Between 30 and 70 years old -Both HIV-positive and HIV-negative individuals with and without chronic obstructive pulmonary disease (COPD) -If HIV-positive, on a stable three-drug ART regimen with undetectable viral load for past 6 months
6/29/2016 

​Additional Clinical Trails

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DENVER FOLLOW-UP AT CHILD AGE 6 OF NURSE AND PARAPROFESSIONAL HOME VISITING FOR MOTHER'S AND CHILDREN
Olds, David L Ph.D.00-036
IMMUNOHISTOCHEMICAL AND PCR-BASED CHARACTERIZATION OF ARCHIVAL SURGICAL PATHOLOGY SPECIMENS
Thor, Ann Denise MD00-1094
CCG-1991-ESCALATING DOSE INTRAVENOUS METHOTREXATE WITHOUT LEUCOVORIN RESCUE VS. ORAL METHOTREXATE AND SINGLE VS DOUBLE DELAYED INTENSIFICATION THERAPY FOR CHILDREN WITH STANDARD RISK ACUTE LYMPHOBLASTIC LEUKEMIA (ALL)
Garrington, Timothy P M.D.00-583
COG-P9645: INTERGROUP PROTOCOL FOR TREATMENT OF CHILDREN WITH HEPATOBLASTOMA
Greffe, Brian S01-112
THE ROLE OF PLATELET ACTIVATING FACTOR-LIKE LIPIDS IN PATIENTS WITH TRANSFUSION RELATED ACUTE LUNG INJURY
Silliman, Christopher M.D.01-196
COG-ANBL00B1 NEUROBLASTOMA BIOLOGY STUDIES
Greffe, Brian S01-209
COG-A3973: A RANDOMIZED STUDY OF PURGED VERSUS UNPURGED PERIPHERAL BLOOD STEM CELL TRANSPLANT FOLLOWING DOSE INTENSIVE INDUCTION THERAPY FOR HIGH RISK NEUROBLASTOMA
Greffe, Brian S01-210
AMERICAN INDIAN CHILD DEVELOPMENT & ATTACHMENT
Sarche, Michelle Christensen01-233
A STUDY OF THE EFFECTIVENESS AND TOLERABILITY OF WEEKLY RIFAPENTINE/ISONIAZID FOR THREE MONTHS VERSUS DAILY ISONIAZID FOR NINE MONTHS FOR THE TREATMENT OF LATENT TUBERCULOSIS INFECTION [TBTC STUDY 26]
Gardner, Edward M M.D.01-284
GENETIC STUDIES OF AUTOSOMAL DOMINANT POLYCYSTIC KIDNEY DISEASE
Gitomer, Berenice Y Ph.D.01-286
Pathogenic and Regulatory T and B Cell Responses in Type 1 Diabetes and Other Autoimmune Diseases
Gottlieb, Peter Ashley M.D.01-384
CHOLESTEROL AND ANTIOXIDANT TREATMENT IN PATIENTS WITH THE SMITH-LEMLI-OPITZ SYNDROME (SLOS)
Elias, Ellen Roy M.D.01-410
CONTINUATION OF CHILDREN ENROLLED IN PROTOCOL #95-11, "A RANDOMIZED PROSPECTIVE STUDY FOR THE PREVENTION OF JOINT DISEASE IN CHILDREN WITH SEVERE FACTOR VIII DEFICIENCY."
Manco-Johnson, Marilyn M.D.01-436
EFFECTS OF PRENATAL NICOTINE EXPOSURE AND A PARENTAL HISTORY FOR SCHIZOPHRENIA ON SACCADIC EYE MOVEMENT PARAMETERS IN INFANTS
Ross, Randal G MD01-561
AGRICULTURE, MATERNAL-INFANT NUTRITION & PUBLIC HEALTH PROYECTO MADRES DE MAIZ
Hambidge, K Michael01-596
ANBL0032 PHASE III RANDOMIZED STUDY OF CHIMERIC ANTIBODY 14.18 (CH 14.18) IN HIGH RISK NEUROBLASTOMA FOLLOWING MYELOABLATIVE THERAPY AND AUTOLOGOUS STEM CELL RESCUE
Greffe, Brian S01-932
SEARCH FOR DIABETES IN YOUTH
Dabelea, Dana M. MD, PhD01-934
ALOPECIA AREATA REGISTRY AND IMMUNOGENETIC MECHANISMS
Norris, David A02-043
P9851 OSTEOSARCOMA BIOLOGY PROTOCOL
Garrington, Timothy P M.D.02-080
AEWS0031 TRIAL OF CHEMOTHERAPY INTENSIFICATION THROUGH INTERVAL COMPRESSION IN EWING SARCOMA AND RELATED TUMORS
Garrington, Timothy P M.D.02-081
SURVEILLANCE OF THE RADARS SYSTEM BY POISON CONTROL CENTERS.
Dart, Richard C02-139
CELIAC DISEASE IN TYPE I DIABETES: GROWTH AND BONE MINERALIZATION
Frohnert, Brigitte I M.D, PhD02-175
PACTG P1025: PERINATAL CORE PROTOCOL
McFarland, Elizabeth J M.D.02-294
QUALITY OF LIFE IN SURVIVORS OF CHILDHOOD BRAIN TUMORS: A FOLLOW-UP STUDY
Foreman, Nicholas K MD02-301
CYSTIC FIBROSIS FOUNDATION NATIONAL PATIENT REGISTRY
Sagel, Scott D MD, PhD02-349
ANBL00P2 PERINATAL NEUROBLASTOMA: EXPECTANT OBSERVATION
Greffe, Brian S02-390
FOSTERING HEALTHY FUTURES STUDY
Taussig, Heather N PhD02-516
EFFICACY OF AGGRESSIVE RENIN-ANGIOTENSIN-ALDOSTERONE AXIS BLOCKADE IN PREVENTING/SLOWING RENAL FUNCTION DECLINE IN ADPKD
Schrier, Robert W02-744
THE ACUTE CHEST SYNDROME IN SICKLE CELL ANEMIA: THE ROLL OF THE NEUTROPHIL
Silliman, Christopher M.D.02-749
SEARCH-CC
Dabelea, Dana M. MD, PhD02-825


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