|Type 2 Diabetes and Exercise Research Study|
To research the effects of an investigational drug on
exercise capacity and blood vessel function.
Person 30-60 with Type 2 diabetes who exercise vigorously less than one hour per week and have normal blood pressure. Must not have smoked for at least one year and have a BMI between 25-39.9.
|Volunteers with Chronic Kidney Disease needed for a Uric Acid Lowering Research Study|
To understand the effect of lowering serum uric acid levels on vascular function in individuals with CKD by comparing Allopurinol therapy and a placebo.
Persons 18+ with moderate chronic kidney disease (CKD stage III) with estimated glomerular filtration rates between 30-60 mL/min/1.73m2
|Are you a woman between the ages of 40 & 52|
To study the effects of medication on perimenopausal symptoms.
Women 40-52 who have regular periods and any hot flashes, cyclical bloating, mood changes, headaches or trouble sleeping
|Research Study: "Anxiety Risk in Teens"|
To learn more about risk factors for anxiety in adolescents with cyclic vomiting syndrome.
Adolescents 13-18 who have been diagnosed with either an anxiety disorder or cyclic vomiting syndrome
|Are you interested in learning about how your breast milk helps your baby grow?|
To find out how maternal size and diabetes status affect her breast milk
To find out what unique parts of breast milk may affect how infants grow.
To learn how to ensure infants receive the best nutrition possible
Women 20-35 who are at least 28 weeks into their pregnancy and planning on exclusively breastfeeding their infant for at least 4 months and delivering at University of Colorado Hospital.
|Free Family Therapy for Youth with Mood Problems|
Helping youth and their families understand and cope with mood swings, develop plans for preventing moods from getting worse, communicate more effectively and solve family problems
Youth between 9-17 who has recently had significant mood swings, has at least one parent with bipolar disorder and does not abuse alcohol or substances. Must agree not to participate in family therapy with another provider for the first year.
This study will look at the body's immune response (how the body fights infection) to the onset of genital herpes. 1-2 study visits for blood draws over the course of 3 months.
18+ years of age; have developed an outbreak of genital herpes within the last 10 days.
|Seeking Children Ages 3 to 17 with NO History of Allergies, Eczema or Asthma|
The goal of this study is to determine why some individuals with atopic dermatitis are at increased risk for skin infections.
Between the ages of 3-17
No history of allergies, eczema or asthma
|Induction of Labor at 39 Weeks Pregnant versus Expectant Management|
Pregnant women are invited to participate in a research study which plans to learn more about whether coming to the hospital and having your labor started with medicine (ie., labor induction) at 39 weeks of pregnancy can improve the baby's health at birth when compared with waiting for labor to start on its own.
First pregnancy (no previous pregnancy beyond 20 weeks)
Single baby (not twins or triplets)
Planning to deliver vaginally and are at least 34 weeks pregnant
Plan to deliver at University of Colorado Hospital or Denver Health Hospital
|Pregnant Participants Needed: A Phase II, Multicenter, Randomized, Observer-Blind, Controlled Study to Evaluate Safety and Immunogenicity of a Trivalent Group B Streptococcus (GBS) Vaccine in Healthy Pregnant Women|
Pregnant women are invited to participate in a research study which plans to learn about antibody (substance produced by the body to fight disease) levels in mothers and infants whose mothers have received the GBS vaccine between 24-34 6/7 weeks of their current pregnancy. the study will also look at antibody levels in mother's breast milk.
Healthy pregnant woman 18-40 years of age
24 0/7 through 34 6/7 weeks pregnant
Planning to breastfeed for at least 90 days after delivery
Plan to deliver at University of Colorado Hospital
|Healthy Volunteers Needed|
The Department of Neurology is looking for healthy volunteers
to participate in a research study examining blinking and
spasms in people with Blepharospam compared to healthy
- Between the ages of 50-80 - Must not have any metal in your body - In good general health
|Healthy Volunteers Needed for a research study of drug levels in blood and hair.|
This study plans to learn more about how tenofovir and emtricitabine (Truvada) build up in cells in blood and hair. Participation will include two 12 week dosing periods separated by a 12 week washout period (total duration is 36 weeks). Eligible participants will be given the supply of medications for the study.
Subject is age 18 to 50 years
Subject is ambulatory
Subject is able to comply with directly observed dosing procedures, including use of audio-visual streaming technology
Subject is able to give informed consent
Subject has a minimum scalp hair length of 2 cm in the occipital region.
Subject is NOT pregnant, planning to become pregnant, or currently breastfeeding
Subject is low risk for HIV-1 infection
Subject does NOT have any active psychiatric illness(es), social condition(s), or alcohol/drug abuse
Subject does NOT have history of non-traumatic, pathologic bone fractures
Subject does NOT have any medical conditions that alter red blood cell kinetics
Subject does NOT have any uncontrolled medical conditions that would interfere with the study conditions
Subject does NOT have contraindicated concomitant medications
|Do you have Parkinson's Disease?|
To explore the effects of different doses of endurance exercise in people with PD.
Persons 40-80 who have been diagnosed with Parkinson's Disease and are not yet taking medication or plant to start medication within the next 6 months. You must be willing to begin the exercise program immediately or after a delay of 6 months and willing to do aerobic exercise on a treadmill.
|Do you have Atopic Dermatitis (Eczema)?|
Males and Females between 3 and 80 who have atopic dermatitis or males and females between 8 months and 80 who have a history of, or an active case of eczema hereticum (wide-spread herpes skin infection along with atopic dermatitis.
|Better Control of Type 2 Diabetes May Decrease Your Risk for Cardiovascular Disease.|
To look at the use of an extended release formula of Exenatide compared to a placebo to maintain normal glucose levels. Ultimately to see better control of diabetes and a decrease in cardiovascular disease events.
Person 18+ with Type 2 Diabetes and take no more than 2 diabetes medications with stale doses for the last 3 months. Must not have a planned or anticipated revascularization procedure, but may have a history of cardiovascular disease and must see your primary care physician at least twice a year.
|Are you a Non-smoking Adult between the ages of 45 and 85?|
We are interested in learning more about smoking related lung disease, and need healthy non-smoking participants.
45-85 years old
Non-Hispanic White or African American
No smoking history
No evidence of lung disease
Doctors at the National Institutes of Health are conducting a research study (IRC-004) to investigate whether treating the flu decreases the amount of virus we can detect in your nose, and to understand whether the change in the amount of virus is associated with changes in your symptoms.
Volunteers may be male or female and must:
-be at least 18 years old
-have a history of an influenza-like illness
-have an onset of illness within the past 48 hours
-test positive for influenza
|Alterations in Lung Microbiome in Acute and Chronic HIV Infection|
This is a prospective, observational cohort study. Three groups (A1, A2, and B) will be enrolled in parallel.
-Men and women >/= 18 years.
-Willing to follow all research requirements
-Willing to provide written informed consent
-Group A1- acute HIV infection defined as a high risk HIV exposure within the prior 30 days, or recent HIV-1 seroconversion defined as those with a high risk HIV-1 exposure
-Group A2- healthy controls: HIV-1 seronegative with no high risk HIV-1 exposure in the prior 30 days and no chronic medical illness
-Group B- HIV-1 infection diagnosed by a previous positive antibody or PCR test have been recommended to initiate HAART by their health care provider
You should not be in this study if you are a pregnant or planning to become pregnant.
|Has your child been diagnosed with generalized anxiety disorder?|
to study sleep and brain activity
• between the ages of 12 & 18
• diagnosed with GAD
• not diagnosed with any psychological disorders
AND who are
• without orthodontic braces
• not taking sleep medications
|Volunteers needed to Participate in a Research Study about Rheumatoid Arthritis|
The purpose of this study is to learn more about how rheumatoid arthritis develops by studying people who do not have rheumatoid arthritis. Your participation in this study will help us determine if certain genetic and environmental factors affect the chances of developing RA-related autoantibodies in absence of rheumatoid arthritis.
You may be eligible to participate in the study if:
-You are at least 18 years old
-You do NOT have Rheumatoid Arthritis (RA)
|Restoring Insulin Secretion (RISE)|
The Children’s Hospital Colorado Clinical Translational Research Center and the
National Institutes of Health are conducting a study. This study is aimed at testing
whether early treatment is beneficial to kids with early type 2 diabetes and
kids at high risk of diabetes.
10-19 years of age, Pubertal, Overweight, Fasting glucose: >90 mg/dl; Impaired glucose tolerance: >140 mg/dl; Pre-diabetes or diagnosed with diabetes for less than 6 months; Metformin
|Participate in a Research Study at the University of Colorado. UC Denver is Conducting a Study on Back Pain and Spinal Manipulation at the Anschutz Medical Campus|
To study muscle activity during chiropractic spinal manipulations
1) 18-55 years of age
3) Must have low back pain
|Have you experienced a preterm birth?|
If you participate, the information we learn from you will help us better understand how and why 1 out of 10 pregnancies in the US end in preterm birth.
1. Women ages 18-45 years old 2. willing to meet for 1-2 hours in a focus group setting 3. a mother of a baby who was born more than 3 weeks before your due date
|Do You Smoke?|
To figure out how these lung substances work in people who drink too much alcohol, who usually smoke, compared to those who do not drink heavily, but who smoke.
Smoking and nonsmoking males
|Parents or Legal Guardians of Children with Disabilities|
Assistive Technology Partners, University of Colorado, Anschutz Medical Campus, is performing a study investigating the impact Socially Assistive Robotics has on motor, communication and cognitive skills of children with disabilities.
Children between the ages of 18 months to 5 years of age Have Significant motor and communication disabilities/delays NOT been diagnosed with blindness or deafness They are without a seizure disorder or with a well-controlled seizure disorder They have been on stable medication regime for the past 12 weeks, if they are currently taking medication.
|Participants with Chronic Kidney Disease and Vitamin D Deficiency Needed for a Research Study|
This study will examine whether nutritional or active
vitamin D supplementation will improve blood vessel
Person 18-80 with chronic kidney disease stage 3B or 4 (estimated GFR 44-15 m;/min) with a vitamin D deficiency or insufficiency. Women must not be pregnant or breastfeeding.
Study the effects of two different study drugs, one or two non-drug interventions and/or a combination of both to treat insomnia.
Persons 21+ who have trouble falling or staying asleep at night.
|Give Us a Hand|
To better understand Multiple Sclerosis in children and teens.
Between the ages of 3-20 AND have Multiple Sclerosis diagnosed before 18
Do not have MS
|Are you an African American with asthma?|
We are studying why some African American people have trouble with their asthma despite taking asthma medications.
Children age 5-17 and non-smoking Adults age18 and older who have asthma symptoms despite asthma treatment • African American ancestry (have at least one African American grandparent)
|Seeking healthy persons for testing an investigational drug for mental illness|
Single administration under medical supervision.
Healthy male and female adults, 18-50 years old with no previous or current mental illness. No drug use. Nonsmokers. If female, willing to use birth control.