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Clinical Trials

Volunteer to Be Part of a Research Study

Page through all School of Medicine clinical and research trials below. There are two categories:

  • Detailed Trial Descriptions, submitted by researchers, includes trial specifics and contact information.

  • Additional Clinical Trials, which include basic study details. To contact the researcher either Google the PI (primary investigator) name or use our campus directory.

If you are a researcher seeking volunteers and your study is not posted, please
submit your Web ad here.

Detailed Trial Descriptions

 Results From Research and Clinical Trials : Selected site
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COMIRB Approved Advertisement TitleStudy GoalsEligibility CriteriaDate PostedCategory
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Do you have Atopic Dermatitis (Eczema)?
To study eczema
Males and Females between 3 and 80 who have atopic dermatitis or males and females between 8 months and 80 who have a history of, or an active case of eczema hereticum (wide-spread herpes skin infection along with atopic dermatitis.
Type 2 Diabetes and Exercise Research Study
To research the effects of an investigational drug on exercise capacity and blood vessel function​.​
Person 30-60 with Type 2 diabetes who exercise vigorously less than one hour per week and have normal blood pressure. Must not have smoked for at least one year and have a BMI between 25-39.9.
Are you a Non-smoking Adult between the ages of 45 and 85?
We are interested in learning more about smoking related lung disease, and need healthy non-smoking participants.
45-85 years old Non-Hispanic White or African American No smoking history No evidence of lung disease
Volunteers needed to Participate in a Research Study about Rheumatoid Arthritis
The purpose of this study is to learn more about how rheumatoid arthritis develops by studying people who do not have rheumatoid arthritis. Your participation in this study will help us determine if certain genetic and environmental factors affect the chances of developing RA-related autoantibodies in absence of rheumatoid arthritis.
You may be eligible to participate in the study if: -You are at least 40 years old -You do NOT have Rheumatoid Arthritis (RA)
Restoring Insulin Secretion (RISE)
The Children’s Hospital Colorado Clinical Translational Research Center and the National Institutes of Health are conducting a study. This study is aimed at testing whether early treatment is beneficial to kids with early type 2 diabetes and kids at high risk of diabetes.
10-19 years of age, Pubertal, Overweight, Fasting glucose: >90 mg/dl; Impaired glucose tolerance: >140 mg/dl; Pre-diabetes or diagnosed with diabetes for less than 6 months; Metformin
Do You Smoke?
To figure out how these lung substances work in people who drink too much alcohol, who usually smoke, compared to those who do not drink heavily, but who smoke.
Smoking and nonsmoking males
Parents or Legal Guardians of Children with Disabilities
Assistive Technology Partners, University of Colorado, Anschutz Medical Campus, is performing a study investigating the impact Socially Assistive Robotics has on motor, communication and cognitive skills of children with disabilities.
Children between the ages of 18 months to 5 years of age Have Significant motor and communication disabilities/delays NOT been diagnosed with blindness or deafness They are without a seizure disorder or with a well-controlled seizure disorder They have been on stable medication regime for the past 12 weeks, if they are currently taking medication.
Help Us Learn About Schizophrenia!
Help us learn more about a new drug that may improve thinking and concentration in people with schizophrenia.
We are looking for: Male and female adults who smoke 18-50 years old No previous or current mental illness No drug use Willing to use nicotine patch during study hospital visit If female, willing to use birth control during the study
Research Trial Evaluating a New Drug in Psoriasis: Now Enrolling
The study will evaluate an investigational drug compared to a currently approved psoriasis medication. Your participation will provide valuable information to researchers seeking new and improved therapies. You will be given either Humira, placebo, or the investigational drug for up to 28 weeks, after which you may be switched over to the active drug depending on your response.
You may be eligible to participate if 18 years of age or older and have been diagnosed with moderate to severe plaque-type psoriasis for at least 6 months.
Do you have high blood pressure?
Study to help predict if blood pressure medications will work for you.
You may be eligible if you are an adult aged 30-80 with a diagnosis of uncontrolled essential hypertension. You must not have a history of end stage liver or renal disease, cannot be pregnant, and cannot be allergic to metoprolol.
8/18/2017Heart and Blood Diseases
Volunteers Needed for a Research Study about Rheumatoid Arthritis
The purpose of this study is to learn more about rheumatoid arthritis. Your participation in this study will help us determine if gum disease affects the chances of developing protein markers associated with rheumatoid arthritis.
1. You are at least 18 years old 2. You do NOT wear dentures 3. You do NOT take antibiotics prior to any dental work or cleaning 4. You HAVE rheumatoid arthritis diagnosed in the last 3 years OR you HAVE lupus or Sjogren’s syndrome diagnosed at any time in the past
8/18/2017Immune System Diseases
Healthy Females Needed
For brain imaging research study on how the brain works with we taste sweets or receive money. Your participation could help us to develop treatments and preventive measures for anorexia nervosa and obesity
Healthy females 16 to 35 who are right-handed, free of medication with no serious medical conditions, permanent metal implants or braces/retainers, and are at a healthy body weight.
8/18/2017--Select a Category--
The University of Colorado Denver School of Medicine is conducting a research study to learn more about an investigational vaccine to prevent C Difficile infection (C diff). C diff is a diarrheal disease that is often difficult to treat and get rid of, particularly in people who are at greater risk.
You may be eligible to participate if you: • Are age 50 or older, • Have never had C diff illness or vaccine • Have had one of the following: o Antibiotics in the last 12 weeks, OR o In the last 12 months – 2 nights hospital stay, OR 2 ER visits, OR 10 outpatient visits, AND o Can provide documentation of the above.
8/18/2017Bacterial and Fungal Diseases
Women with History of Pregnancy Induced High Blood Pressure Needed for Cardiovascular Research Study
The purpose of this study is to investigate how the menopause transition and the loss of estrogen impacts the health and function of the heart and arteries in women who developed high blood pressure during past pregnancies.
-Premenopausal women 18-55 years -Perimenopausal women 40-55 years -Postmenopausal women 45-70 years -Pregnancy history of any of the following: pregnancy-induced high blood pressure, preeclampsia, eclampsia, gestational high blood pressure -Nonsmokers -NOT currently taking birth control or hormone replacement therapy or exercising vigorously more than 2 days per week
8/18/2017Heart and Blood Diseases
Give Us a Hand
To better understand Multiple Sclerosis in children and teens.
Between the ages of 3-20 AND have Multiple Sclerosis diagnosed before 18 OR Do not have MS
Are you an African American with asthma?
 We are studying why some African American people have trouble with their asthma despite taking asthma medications.
 Children age 5-17 and non-smoking Adults age18 and older who have asthma symptoms despite asthma treatment • African American ancestry (have at least one    African American grandparent)
Do you have human growth hormone (hGH) deficiency?
Primary: To demonstrate a clinical superiority of MOD-4023 over placebo in terms of decrease in Fat Mass (FM) in adult subjects with Growth Hormone Deficiency Secondary a. To determine the efficacy of MOD-4023 over placebo in other body composition variables (such as lean body mass and waist-to-hip ratio) b. To evaluate the safety and tolerability of MOD-4023 over placebo in adult subjects with GHD c. To determine the IGF-I and IGFBP-3 serum levels
Adult men and women aged 23 to 70 years of age diagnosed with either adult or childhood onset growth hormone deficiency (GHD).
Do you have an egg allergy?
To see if taking Baked Egg Therapy vs. Oral Immunotherapy may help egg-allergic children tolerate eggs.
males and females 3 to 16 years old, with documented egg allergy, ability to make regular visits to National Jewish Health for up to 2 years.
Randomized Trial to Prevent Vascular Events in HIV (REPRIEVE)
Pitavastatin is a statin that along with diet is used for the treatment of high cholesterol. It also lowers triglyceride levels in the blood. The main purpose of this clinical trial is to see if pitavastatin can prevent heart disease and heart disease related deaths in people with HIV infection who are taking HIV medications.
This study lasts about 6 years (21 visits) and you may be eligible if: • You have HIV and are between the ages of 40 and 75. • You have been on antiretroviral therapy (ART) for at least 6 months. • You have a CD4+ cell count > 100. • You have no history of cardiovascular disease (history of heart attack or stroke, etc.). • You are not currently using a statin drug.
Are You a Healthy Individual Looking to Help With Research
This is a research study to learn more about the risk factors, features, and treatment or prevention efforts for bleeding disorders.
Aged 1 to 17 Healthy
8/17/2017--Select a Category--
Are you interested in participating in a research study to help us learn more about where the fat tissue in your body originates? MYTH Study
This research study plans to learn more about where the fat cells in your body come from.  Understanding the origin of fat cells is important because it may help to determine the health of fat cells and why fat that is stored in some places of your body is more "unhealthy" than other fat.
We are enrolling men and women who are: Age 21-40 y or 55-85 y; BMI 22-35 kg/m2; Weight stable (not actively gaining or trying to lose weight); Non-active to moderately active (exercise ≤ 3 days/wk lasting < 30 min); Not taking any hormonal therapy (testosterone, estrogen/progesterone replacement, or hormonal contraceptives); Not diagnosed with type 2 diabetes or taking glucose or lipid lowering medication; Not pregnant or planning to become pregnant in the next month
8/17/2017Nutritional and Metabolic Diseases
Research study on the effects of an investigational drug on weight and neuronal response
This research study plans to examine the effects of an investigational new drug on neuronal, physiological, and behavioral mechanisms of obesity in the general population.
To be eligible for the study, participants must have a BMI greater than 27 kg/m2, be 21-65 years old, be a non-smoker, have no known cardiovascular disease, have no significant endocrine/metabolic disease, must not be pregnant or trying to conceive, and must be able to complete an MRI scan.
8/17/2017Behaviors and Mental Disorders
Volunteers Needed for a Research Study about Rheumatoid Arthritis
The purpose of this study is to learn more about rheumatoid arthritis by studying people who do not have rheumatoid arthritis. Your participation in this study will help us determine if gum disease affects the chances of developing protein markers associated with rheumatoid arthritis.
You are at least 40 years old • You do NOT have rheumatoid arthritis (RA)
8/17/2017--Select a Category--
Feasibility Study of Metformin Therapy in ADPKD
The primary purpose of the research study is to determine the safety and tolerability of the study drug (Metformin or placebo) when given to subjects with ADPKD (Autosomal Dominant Polycystic Kidney Disease).
Age 30 - 60 Confirmed diagnosis of ADPKD Estimated glomerular filtration rate between 50 and 75 mL/min/1.73 m2, inclusive Controlled blood pressure at < 130/80 mmHg on a stable antihypertensive regimen for at least 4 weeks
8/17/2017Symptoms and General Pathology
We are Currently Enrolling People with Down syndrome for a study in Dr. Pelak's Brain and Vision Research lab at the University of Colorado Anschutz Medical Campus.
To examine visual brain function in people with mild memory impairments to detect early signs of Alzheimer's Disease.​
Persons 19-30 who have Down Syndrome
EMERALD STUDY: Effects of MEtformin on CardiovasculaR function in AdoLescents with Type 1 Diabetes
​To determine the effects of Metformin on Cardiovascular Function in Adolescents with Type 1 Diabetes.
  • Persons 12-21 who have Type 1 Diabetes
  • Non-smoker, able to ride a stationary bike
  • You must be willing to take metformin or placebo (sugar pill) for 3 months.
  • Other exclusions apply, please contract study for more information
Exercise and Cancer Prevention Research Study
The goal of this study is to better understand the biological mechanisms associated with exercise and reduced risk for breast cancer.
  • You must be a female between the ages of 30-45 to participate in this study. 
  • You must be planning to live in the Denver metropolitan area for the next 10 consecutive months. 
  • You should not be a regular exerciser because this study is for people who do not exercise right now; however, you should be willing to participate in an exercise program 4 times per week for 16-weeks.
Are you interested in a supervised exercise intervention?
Volunteers are needed for a research study to examine the effects of exercise on food intake and appetite regulation.
  • 21-45 years old
  • Non- smoker
  • Non- Diabetic
  • Exercise no more than 1 time a week
  • Maintained your current weight for last 6 months
  • Have a body mass index (BMI) of 27-35 (check it out at
Study of Mood Disorder in Preschool Children
We are doing a research study to better understand what mood disorders look like in preschool children.
We are looking for volunteers who:  
  • Are parents of children between the ages of 4 and 6 years 0 months.
  • Are in one of three groups:
    1. Their child has no major mental health problems, and there is no family history of major mood or psychotic disorders.
    2. Their child has been diagnosed with a mood disorder, bipolar disorder, or mood dysregulation disorder. 
    3. Their child has been diagnosed with attention deficit hyperactivity  disorder (ADHD).  
  • Parents or guardians will be asked to:
    • Read and sign a consent form
    • Participate in interviews about their children
  • The  children will be asked to:
    • Participate in a story game
    • Take tests of verbal and nonverbal abilities
How much time will this take?
The visit for the child will last from 1 to 2 hours.  The visit for the parents will last 3 to 5 hours.
Understanding how Tysabri and Gilenya Influence the Quality of your Daily Life with Multiple Sclerosis
The purpose of this research study is to compare two medications, Tysabri and Gilenya, used in the treatment of multiple sclerosis (MS), through a few self-reported patient surveys. We will ask you to complete online surveys about overall health-related quality of life, disability, fatigue, cognition and productivity. We will also want to review your medical records to understand your MS history with your permission. This study will help us understand how these drugs are impacting each aspect of your daily lives.
  • Between ages 16 and 65
  • Scheduled to start natalizumab or fingolimod for the first time to treat your MS

Contact Us

Brenda Crawford, Research Coordinator, (303) 724-5362

Building 500 - 13001 E. 17th Place, Campus Box C290, Aurora, CO 80045

Learn more