|Cognitive Dysfunction in Parkinson's Disease|
This research study plans to use simultaneous brain scans and memory tasks to see if stimulating certain areas of the brain improves thinking and memory. This is not a treatment study
Healthy males over 50 with Parkinson's disease on stable doses of medication and have no metal in the body (dental work may be ok).
|EFFECTS OF TESTOSTERONE THERAPY IN YOUNG ADOLESCENTS WITH KLINEFELTER SNDROME (47.XXY)|
This study will study the effects of testosterone therapy on behavior, mood, problem solving, attention span, and motor skills in adolescent males with Klinefelter syndrome in early puberty. During this period in early puberty there is a lot of variability in how and when doctors start testosterone therapy. This study will evaluate if there are benefits to starting testosterone therapy in early puberty.
Participants with Klinefelter syndrome in early puberty (around age 10-15).
|Are you a Parkinson's patient not requiring symptomatic treatment with drugs?|
This research study explores the effects of an FDA approved drug on Parkinson's disease.
Recently diagnosed Parkinson's patients who are not taking any drugs for symptomatic relief or are willing to go off drugs for the duration of the study with neurologist approval. We are also looking for healthy control participants.
|Volunteers with Alzheimer’s Disease Needed for Memory Study|
To examine the safety and efficacy of the study drug, Sargramostim (Leukine®), on memory in adults with Mild-to-Moderate Alzheimer’s Disease.
1. Age 55 to 85 years;
2. Should have a mild-to-moderate Alzheimer's Disease diagnosis (Mini-Mental State Examination 10-26 inclusive);
3. If on anti-dementia treatment should be on stable treatment for at least 2 months (i.e. cholinesterase inhibitor and/or Memantine or Axona);
4. Stable on all other medications for at least 30 days prior to screen;
5. Should be fluent in English;
6. Should be physically able to participate by medical history, clinical exam and tests;
7. Should have a study partner to accompany them to scheduled visits.
|Do you have high blood pressure?|
Researchers at the University of Colorado Hospital are conducting a research study to help predict if blood pressure medications will work for you.
Subject must be between 30 and 75 years of age and have a diagnosis of uncontrolled hypertension (high blood pressure). As part of the study, you may be eligible for free medication and free clinic visits to check your blood pressure
|T•A•C•I•T - Therapy After Cochlear Implants Using Telemedicine |
This research plans to learn more about the use of telemedicine as a means of providing therapy to children who have a cochlear implant(s). While Auditory-Verbal Therapy has typically been delivered in person, many people are starting to access therapy over the internet. We are conducting this research to determine if the outcomes of therapy are the same when AVT is delivered in person and via telemedicine.
The T•A•C•I•T team is looking for children ages 6 mos.-6 yrs. old who were implanted with cochlear implant(s) before age 3 ½.. Each child will spend nine months in both the in-person and telemedicine condition. The therapist will remain the same throughout the study. Total participation will last 18 months. The child will be tested three times: once when the study starts, and every nine months after that. A qualified study team member will administer speech, listening, and language tests to the child. They will also receive tests to identify how well their auditory area of the brain is developing.
|Participants with Chronic Kidney Disease Needed for a Research Study about Phosphate|
We are looking for men and women to participate in a research study examining whether
lowering blood levels of phosphate will improve blood vessel function.
We need men and women who:
-are age 40-79 years old; women must be post-menopausal;
-have chronic kidney disease stage 3b or 4 (estimated GFR 15-45 ml/min);
-are not taking phosphate binders;
-do not have high blood phosphate (>5.5 mg/dL).
Bayer HealthCare is sponsoring a medical research study to look at the effectiveness of Essure after having a procedure (NovaSure) that decreases your heavy menstrual bleeding. Both Essure and NovaSure are approved by the FDA.
This study is enrolling patients now and you may qualify to participate.
Are you currently using the Essure method of contraception?
Are your periods heavy, frequent or prolonged?
One important prerequisite is - you must have had a successful Essure placement AND be willing to undergo a NovaSure endometrial ablation, a treatment option for heavy menstrual bleeding (menorrhagia).
|Volunteers Needed for Cardiovascular Research Study at the Division of Renal Diseases and Hypertension Clinical Research Unit|
This research study will compare blood vessel function in healthy adults to adults with two different types of kidney disease. The testing visit will include non-invasive testing of blood vessel function and collection of blood and cells from an IV. As a volunteer, you will receive the following information about your health:resting EKG; blood cholesterol screening,
blood sugar screening, blood pressure screening, and physical Exam.
We are looking for men and women, aged 18-80 years, non-smokers, generally healthy, and free from hypertension. Women must not be pregnant of trying to become pregnant
|2/9/2016||--Select a Category--
|Research Study: "Anxiety Risk in Teens"|
To learn more about risk factors for anxiety in adolescents with cyclic vomiting syndrome.
Adolescents 13-18 who have been diagnosed with either an anxiety disorder or cyclic vomiting syndrome
|Are you interested in learning about how your breast milk helps your baby grow?|
To find out how maternal size and diabetes status affect her breast milk
To find out what unique parts of breast milk may affect how infants grow.
To learn how to ensure infants receive the best nutrition possible
Women 20-35 who are at least 28 weeks into their pregnancy and planning on exclusively breastfeeding their infant for at least 4 months and delivering at University of Colorado Hospital.
|Free Family Therapy for Youth with Mood Problems|
Helping youth and their families understand and cope with mood swings, develop plans for preventing moods from getting worse, communicate more effectively and solve family problems
- Youth between 9-17 who has recently had significant mood swings, has at least one parent with bipolar disorder and does not abuse alcohol or substances.
- Must agree not to participate in family therapy with another provider for the first year.
This study will look at the body's immune response (how the body fights infection) to the onset of genital herpes. 1-2 study visits for blood draws over the course of 3 months.
- 18+ years of age
- Have developed an outbreak of genital herpes within the last 10 days.
|Pregnant Participants Needed:|
Pregnant women are invited to participate in a research study which plans to learn about antibody (substance produced by the body to fight disease) levels in mothers and infants whose mothers have received the GBS vaccine between 24-34 6/7 weeks of their current pregnancy. the study will also look at antibody levels in mother's breast milk.
- Healthy pregnant woman 18-40 years of age
24 0/7 through 34 6/7 weeks pregnant
- Planning to breastfeed for at least 90 days after delivery
- Plan to deliver at University of Colorado Hospital
|Healthy Males needed for a research study of drug levels in blood and hair.|
This study plans to learn more about how tenofovir and emtricitabine (Truvada) build up in cells in blood and hair. Participation will include two 12 week dosing periods separated by a 12 week washout period (total duration is 36 weeks). Eligible participants will be given the supply of medications for the study.
- Must be age 18 to 50 years
- Must own smartphone
- Subject has a minimum scalp hair length of 2 cm in the occipital region.
- Have a low risk for HIV-1 infection
|The Role of Gut Bacteria in the Development of Type 1 Diabetes.|
The goal of the research is to better understand the role bacteria that live in the intestine in the development of type 1 diabetes
- Patients diagnosed with type 1 diabetes in the last 6 months
- Subjects with islet autoantibodies
- Subjects who do not have islet antibodies and are first-degree relatives of patients with diabetes or subjects with islet antibodies
- 1-45 years of age
|Are you interested in participating in a research study to help us learn more about where the fat tissue in your body originates?|
To understand if some fat cells (adipocytes) may originally come from cells in the bone marrow. Understanding the origin of fat cells is important because it may help to determine the health of fat cells and why fat that is stored in some places of your body is more ‘unhealthy’ than other fat.
Men and women:
Between the ages of 18 and 75 years AND
Had an allogeneic hematopoietic stem cell transplant at least 6 months ago –OR–
Have chronic phase chronic myeloid leukemia.
|2/8/2016||Nutritional and Metabolic Diseases
|Interested in participating in a free weight loss class?|
The CU Anschutz Health and Wellness Center is seeking volunteers for a new weight loss
research study looking at the role of beef intake for weight loss and weight maintenance. The
study will last approximately 6 months. Participants will participate in a 16-week State of Slim
weight loss program at no cost and receive monetary stipends to be used to purchase State of
Slim-friendly protein foods. Participants will receive body composition scans, lab work and
wellness assessments at no charge and have access to the Anschutz Health and Wellness
Fitness Center during the study.
Are between 18 - 50 years old
Are overweight or obese (BMI ≥ 27) - Check your BMI at:
Are willing to participate in weekly group weight loss classes for 16 weeks and attend
four study visits over a 6 month period at the Anschutz Medical Campus
Are not vegetarian
Are not diabetic
Are not allergic to red meat or other common protein sources
|2/8/2016||Nutritional and Metabolic Diseases
|Tell us your story...|
To learn more about reproductive health of Latina and Hispanic women
Born in the U.S.
Both parents born in the U.S.
A grandparent or great-grandparent born in Mexico OR of Hispanic origin
|2/8/2016||--Select a Category--
|Are you interested in learning more about daily blood sugar changes in your child?|
The Endocrinology department at Children’s Hospital Colorado is looking for
children and young adults interested in learning about day-to-day blood sugar
The study involves a single visit where diabetes screening will be provided as
well as placement of a continuous sugar monitor to be worn for up to 7 days.
Age 10-25 years
BMI < 85%ile
|2/8/2016||Nutritional and Metabolic Diseases
|Do you have Parkinson's Disease?|
To explore the effects of different doses of endurance exercise in people with PD.
Persons 40-80 who have been diagnosed with Parkinson's Disease and are not yet taking medication or plant to start medication within the next 6 months. You must be willing to begin the exercise program immediately or after a delay of 6 months and willing to do aerobic exercise on a treadmill.
|Do you have Atopic Dermatitis (Eczema)?|
Males and Females between 3 and 80 who have atopic dermatitis or males and females between 8 months and 80 who have a history of, or an active case of eczema hereticum (wide-spread herpes skin infection along with atopic dermatitis.
|Better Control of Type 2 Diabetes May Decrease Your Risk for Cardiovascular Disease.|
To look at the use of an extended release formula of Exenatide compared to a placebo to maintain normal glucose levels. Ultimately to see better control of diabetes and a decrease in cardiovascular disease events.
Person 18+ with Type 2 Diabetes and take no more than 2 diabetes medications with stale doses for the last 3 months. Must not have a planned or anticipated revascularization procedure, but may have a history of cardiovascular disease and must see your primary care physician at least twice a year.
|Type 2 Diabetes and Exercise Research Study|
To research the effects of an investigational drug on
exercise capacity and blood vessel function.
Person 30-60 with Type 2 diabetes who exercise vigorously less than one hour per week and have normal blood pressure. Must not have smoked for at least one year and have a BMI between 25-39.9.
|Are you a Non-smoking Adult between the ages of 45 and 85?|
We are interested in learning more about smoking related lung disease, and need healthy non-smoking participants.
45-85 years old
Non-Hispanic White or African American
No smoking history
No evidence of lung disease
|Alterations in Lung Microbiome in Acute and Chronic HIV Infection|
This is a prospective, observational cohort study. Three groups (A1, A2, and B) will be enrolled in parallel.
-Men and women >/= 18 years.
-Willing to follow all research requirements
-Willing to provide written informed consent
-Group A1- acute HIV infection defined as a high risk HIV exposure within the prior 30 days, or recent HIV-1 seroconversion defined as those with a high risk HIV-1 exposure
-Group A2- healthy controls: HIV-1 seronegative with no high risk HIV-1 exposure in the prior 30 days and no chronic medical illness
-Group B- HIV-1 infection diagnosed by a previous positive antibody or PCR test have been recommended to initiate HAART by their health care provider
You should not be in this study if you are a pregnant or planning to become pregnant.
|Volunteers needed to Participate in a Research Study about Rheumatoid Arthritis|
The purpose of this study is to learn more about how rheumatoid arthritis develops by studying people who do not have rheumatoid arthritis. Your participation in this study will help us determine if certain genetic and environmental factors affect the chances of developing RA-related autoantibodies in absence of rheumatoid arthritis.
You may be eligible to participate in the study if: -You are at least 40 years old -You do NOT have Rheumatoid Arthritis (RA)
|Restoring Insulin Secretion (RISE)|
The Children’s Hospital Colorado Clinical Translational Research Center and the
National Institutes of Health are conducting a study. This study is aimed at testing
whether early treatment is beneficial to kids with early type 2 diabetes and
kids at high risk of diabetes.
10-19 years of age, Pubertal, Overweight, Fasting glucose: >90 mg/dl; Impaired glucose tolerance: >140 mg/dl; Pre-diabetes or diagnosed with diabetes for less than 6 months; Metformin
|Do You Smoke?|
To figure out how these lung substances work in people who drink too much alcohol, who usually smoke, compared to those who do not drink heavily, but who smoke.
Smoking and nonsmoking males
|Parents or Legal Guardians of Children with Disabilities|
Assistive Technology Partners, University of Colorado, Anschutz Medical Campus, is performing a study investigating the impact Socially Assistive Robotics has on motor, communication and cognitive skills of children with disabilities.
Children between the ages of 18 months to 5 years of age Have Significant motor and communication disabilities/delays NOT been diagnosed with blindness or deafness They are without a seizure disorder or with a well-controlled seizure disorder They have been on stable medication regime for the past 12 weeks, if they are currently taking medication.