Skip to main content
Sign In
 

Clinical Trials

Volunteer to Be Part of a Research Study


You can search for specific diseases or conditions in our Clinical Trials list (the page takes a few seconds to load due to the quantity of trials).

Page through all School of Medicine clinical and research trials below, or click here to look for specific types of trials.
(It will take a few seconds to load) There are two categories: 

  • Detailed Trial Descriptions, submitted by researchers, includes trial specifics and contact information.

  • Additional Clinical Trials, which include basic study details. To contact the researcher either Google the PI (primary investigator) name or use our campus directory.

If you are a researcher seeking volunteers and your study is not posted, please submit your Web ad here.  

Detailed Trial Descriptions

 Results From Research and Clinical Trials : Selected site
Data pager
<
>
Page Size
PageSizeComboBox
select
 |  Displaying page 1 of 4, items 1 to 30 of 93.
COMIRB Approved Advertisement TitleStudy GoalsEligibility CriteriaDate Posted
Data pager
<
>
Page Size
PageSizeComboBox
select
 |  Displaying page 1 of 4, items 1 to 30 of 93.
Participants with Chronic Kidney Disease and Vitamin D Deficiency Needed for a Research Study
This study will examine whether nutritional or active vitamin D supplementation will improve blood vessel function​.
Person 18-80 with chronic kidney disease stage 3B or 4 (estimated GFR 44-15 m;/min) with a vitamin D deficiency or insufficiency.  Women must not be pregnant or breastfeeding.
4/17/2014
Asthmatics Needed
Test pulmonary function.
Person 18+ who have been diagnosed with asthma , do not smoke and are currently on inhaled steroid or other daily controller medications.
4/17/2014
Trouble Sleeping?
Study the effects of two different study drugs, one or two non-drug interventions and/or a combination of both to treat insomnia.
Persons 21+ who have trouble falling or staying asleep at night.
4/17/2014
MS Volunteers Needed for Research Study
Looking to see if there is a cognitive improvement with the treatment of oral estriol as compared to oral placebo.
We are looking for: • Women 18-50 years old • Diagnosed with definite relapsing-remitting, secondary-progressive multiple sclerosis or primary-progressive multiple sclerosis • MS disease duration of 15 years or less • On stable dose of standard MS treatment with Copaxone®, Betaseron® (or Extavia®), Rebif®,Avonex®, Gilenya®, Aubagio®, Tecfidera®, or no treatment ----You are not eligible for the study if you are pregnant, breast-feeding, smoke, or have other serious medical conditions.
4/17/2014
Give Us a Hand
To better understand Multiple Sclerosis in children and teens.
Between the ages of 3-20 AND have Multiple Sclerosis diagnosed before 18 OR Do not have MS
4/17/2014
Healthy subjects needed for high altitude research study
For a research study on the effects of drugs on blood oxygen levels
Healthy Male subjects needed that are: - Between the ages of 18-45 years old - Do not smoke - Engage in regular physical exercise - Willing and able to engage in moderate physical activities in a simulated high altitude environment
4/17/2014
Are you an African American with asthma?
 We are studying why some African American people have trouble with their asthma despite taking asthma medications.
 Children age 5-17 and non-smoking Adults age18 and older who have asthma symptoms despite asthma treatment • African American ancestry (have at least one    African American grandparent)
4/17/2014
Seeking healthy persons for testing an investigational drug for mental illness
Single administration under medical supervision. Compensation provided.
Healthy male and female adults, 18-50 years old with no previous or current mental illness. No drug use. Nonsmokers. If female, willing to use birth control.
4/17/2014
If you child suffers from rashes or skin allergies he or she may qualify to take part in a research study.
To test seven new antigens on the child and adolescent population to add to the current standard test
Children and adolescents 6-17 diagnosed with contact dermatitis or may have contact dermatitis who are willing to wear test patches for 2 days and are available for follow-up visits
4/16/2014
Investigations in Gestational Origins of Lifetime Development: Understanding health begins before birth. Are you in your first trimester of Pregnancy?
To learn more about how your metabolism is connected to your baby's growth and development
Healthy Women ages 18-35 who are 10-14 weeks pregnant with single baby.  Norm BMI or 30-38 who are willing to complete 5 visits during pregnancy and agreeable to an infant blood draw at birth and DXA postpartum.  Delivery must be at University of Colorado Hospital.  there is an option to take part in a 1 year follow-up which entails an additional 4 visits and another DXA at 1 year of life.
4/16/2014
We are Currently Enrolling People with Down syndrome for a study in Dr. Pelak's Brain and Vision Research lab at the University of Colorado Anschutz Medical Campus.
To examine visual brain function in people with mild memory impairments to detect early signs of Alzheimer's Disease.​
Persons 19-30 who have Down Syndrome
4/16/2014
You are invited to participate in EMERALD, as research study about Metformin and Type 1 Diabetes in Adolescents
​To determine the effects of Metformin on Cardiovascular Function in Adolescents with Type 1 Diabetes.
Persons 12-21 who have Type 1 Diabetes, non-smoker and exercise no more than 3 hours a week.  You must be willing to take metformin or placebo (sugar pill) for 3 months.   Other exclusions apply, please contract study for more information
4/16/2014
Children's Hospital, department of Pediatric Neurology is conducting a research study
evaluating the effects of a single treatment of injected BOTOX® (Botulinum Toxin Type A) for chronic migraine(s) in adolescents.
Adolescents 12-17 who have no serious medical conditions but have at least 15 headaches a month for the last 6 months. You not have any previous BOTX treatments or are not currently using any prophylactic medicine.
4/16/2014
Non-Alcoholic Fatty Liver Disease and Obstructive Sleep Apnea: Mechanistic Links between Hypoxemia and Liver Injury
To learn if obstructive sleep apnea and low oxygen levels have a role in developing Non-Alcoholic Fatty Liver Disease (NAFLD).​​​
Children 10-17 who have a normal weight and no serious medical problems
4/16/2014
Are you using Implanon or Nexplanon for birth control?
study on a potential treatment for bothersome bleeding/spotting related to the etonogestrel implant.
Women 18-44 who are experiencing bothersome bleeding/spotting while using Implanon or Nexplanon
4/16/2014
Exercise and Cancer Prevention Research Study
The goal of this study is to better understand the biological mechanisms associated with exercise and reduced risk for breast cancer.
You must be a female between the ages of 30-45 to participate in this study. You must be planning to live in the Denver metropolitan area for the next 10 consecutive months. You should not be a regular exerciser because this study is for people who do not exercise right now; however, you should be willing to participate in an exercise program 4 times per week for 16-weeks.
4/16/2014
Blood Donor Volunteers Needed for Research Study
We are trying to learn more about blood loss to provide better treatment for trauma patients. This study plans to learn if non-invasive monitoring can accurately track blood loss and changes in stroke volume.
1. Be approved by CHCO Blood Donation Center for donating blood 2. Be 18-89 years old 3. Have previously donated blood or plasma (at any blood donation center)
4/16/2014
Frequent Cold Sores?
This study will look at the body's immune response (how the body fights infection) to the onset of cold sores.  1-2 study visits for blood draws over the course of 3 months.
18+ years of age; have prior history of cold sores; have developed a cold sore within the last 10 days.
4/16/2014
Brown Adipose Tissue and Estrogen (BATE Study)
To investigate whether estrogen influences the activity of brown adipose tissue.
Healthy non-smoking women 20-40 who have regular menstrual cycles and are not on hormonal contraceptives and exercise more than once per week
4/15/2014
Is your asthma well controlled?
Comparison study involving three FDA approved medications for asthma
Asthmatics 12 and over with symptoms that are well controlled and do not smoke.
4/15/2014
Do you have asthma?
Effects of a CPAP machine on asthma symptoms
Asthmatics 15-90 who do not smoke
4/15/2014
Type 2 Diabetes and Exercise Research Study
Perceived exertion during exercise
Person 50-70 with or without Type 2 diabetes who exercise vigorously less than one hour per week and have normal blood pressure.  You should have a BMI between 25-35 and have not smoked for a least one year.
4/15/2014
Is your child 6-18 years old and interested in participating in a research study?
To study the effects of polycystic kidney disease (PKD) on blood vessel function
Children 6-22 free from kidney disease and other chronic diseases
4/15/2014
Evaluation of Glucose Sensor and Insulin Infusion Set Failures: Lipohypertrophy Study
This study is looking at evaluating Insulin Pump Infusion sites and Continuous Glucose Monitoring sites in tissue with Lipohypertrophy. We will also be looking at using the sites for a longer duration.
Lipohypertrophy site of 3 cm or greater in diameter Ages 12-45 inclusive A1C Value of < 10% Insulin pump use of at least 3 month duration Pump use with Medtronic, Animas or T-slim Willing to wear two CGM's during the 4 weeks of the study
4/15/2014
Healthy subjects needed for high altitude research study
For a research study on how intracranial pressure is related to acute mountain sickness
Between the ages of 18-40 years old - Do not smoke - Engage in regular physical exercise - Willing and able to engage in moderate physical activities in a simulated high altitude environment
4/15/2014
Are you trying to lose weight?
Volunteers needed for a research study about the weight loss medication Phentermine  
Healthy and between 30-45 years of age •Have a BMI between 30 and 40 (calculate your BMI at http://www.nhlbisupport.com/bmi/) •Willing to take the weight loss medication Phentermine for a period of 8 weeks (but not currently taking any approved or investigational medication for weight loss)
4/15/2014
Help us learn about Schizophrenia!
Help us learn more about a new drug that may improve thinking and concentration in people with schizophrenia.
Healthy male and female adults, 18-50 years old with no previous or current mental illness. No drug use. Nonsmokers. If female, willing to use birth control.
4/15/2014
Volunteers With Neck Pain Needed for Research Study
The purpose of the study is to evaluate the effect of mental concentration on nerve and muscle excitability.
Men and women aged 21-50 years with a history of neck pain that is worsened by work or other stressful activities.
4/15/2014
Shingles Vaccine Clinical Research Trial
This study will compare responses to two shingles vaccines - the current FDA approved shingles vaccine and an investigational shingles vaccine - in younger and older people.
50-59 years of age or 70-85 years of age; General good health; No prior history of shingles; Have never received the shingles vaccine; although... a subset of 70-85 year olds who DID receive the shingles vaccine at least 5 years previously is also needed (must be able to provide documentation of vaccination)
4/15/2014
Volunteers needed for a research study of men who are carriers of the Fragile X gene
Study the effects of the Fragile X Tremor-Ataxia Syndrome (FXTAS) on mental abilities and brain functioning.  A better understanding of FXTAS should lead to improved diagnosis, and eventually to means of treating both the symptoms and the disease.
Men age 62 or above who have a least 12 years of education and who have no neurological disorders.
4/14/2014

​Additional Clinical Trails

 Results From Research : Selected site
Data pager
<
>
Page Size
PageSizeComboBox
select
 |  Displaying page 1 of 9, items 1 to 30 of 264.
Protocol TitlePI NameInstitution Number
Data pager
<
>
Page Size
PageSizeComboBox
select
 |  Displaying page 1 of 9, items 1 to 30 of 264.
Engineering Clinical Evaluation of Philips Medical's Modified CX50 with Revision MI 3 Software and Q-Station Software with new Release 9.0.Sponsor Protocol Philips Medical. WIRB Protocol No. 20110948
Salcedo, Ernesto11-0797
Adult Congenital Heart Disease Quality Enhancement Research Initiative (ACHD QuERI). Sponsor Protocol CHRC2011-ACHD001. WIRB Protocol No. 20111582
Kay, Joseph12-1161
The Targeting Acute Congestion with Tolvaptan in Congesting Heart Failure Study (Tactics-HF). WIRB Protocol No. 20121793
Shakar, Simon13-0112
ASPIRE Early Ablation Therapy for the Treatment of Ischemic Ventricular Tachycardia in Patients with Implantable Cardioverter Defibrillators. WIRB Protocol No.20121193
Tzou, Wendy13-0280
A PHASE 3, MULTICENTER, RANDOMIZED, OPEN-LABEL STUDY TO COMPARE THE EFFICACY AND SAFETY OF POMALIDOMIDE, BORTEZOMIB AND LOW-DOSE DEXAMETHASONE VERSUS BORTEZOMIB AND LOW-DOSE DEXAMETHASONE IN SUBJECTS WITH RELAPSED OR REFRACTORY MULTIPLE MYELOMA. Sponsor Protocol # CC-4047-MM-007. WIRB Protocol # 20121754
Smith, Clayton13-2056
Exhibit B-14 Specific Research Plan for Voyager 1.0. WIRB Protocol # 20131141
Salcedo, Ernesto13-2062
A Single-arm Study to Assess the Efficacy and Safety of Oral Rigosertib in Transfusion-dependent, Low or Intermediate-1, Myelodysplastic Syndrome Patients Based on the International Prognostic Scoring System. Sponsor Protocol # 09-07. WIRB Protocol # 20131128
Pollyea, Daniel13-2064
COMBI-AD: A phase III randomized double blind study of dabrafenib (GSK2118436) in COMBInation with trametinib (GSK1120212) versus two placebos in the ADjuvant treatment of high-risk BRAF V600 mutation-positive melanoma after surgical resection. Sponsor Protocol # BRF115532. WIRB Protocol # 20130566
Gonzalez, Rene13-2093
A PROSPECTIVE, RANDOMIZED, CONTROLLED, PARALLEL GROUPS, MULTICENTER POST-APPROVAL STUDY OF THE GLAUKOS® ISTENT® TRABECULAR MICRO-BYPASS STENT SYSTEM IN CONJUNCTION WITH CATARACT SURGERY. SPONSOR PROTOCOL # GTS100-PAS2. WIRB PROTOCOL # 20130739
Seibold, Leonard13-2098
A randomized, double blind, placebo-controlled, multicenter phase III study of regorafenib in patients with hepatocellular carcinoma (HCC) after sorafenib. Sponsor Protocol No. BAY 73-4506 / 15982. WIRB Protocol No. 20121899
Purcell, William13-2135
A Phase I Dose Escalation Open-Label Safety, Pharmacokinetic and Pharmacodynamic Study to Determine the Recommended Phase II Dose of GSK1120212 Dosed in Combination with GSK2141795. Sponsor Protocol No. TAC113886. WIRB Protocol No. 20130890
Gonzalez, Rene13-2146
A Double-Blind, Placebo-Controlled Evaluation of the Safety and Efficacy of Vilazodone in Adolescent Patients with Major Depressive Disorder. Sponsor Protocol No. VLZ-MD-21. WIRB Protocol No. 20130945
Wamboldt, Marianne13-2149
A Phase 2, Randomized, Multicenter Study of PEGPH20 (PEGylated Recombinant Human Hyaluronidase) Combined with nab-Paclitaxel Plus Gemcitabine Compared With nab-Paclitaxel Plus Gemcitabine in Subjects With Stage IV Previously Untreated Pancreatic Cancer. Sponsor Protocol No. HALO-109-202. WIRB Protocol No. 20130824
Weekes, Colin13-2161
A PHASE IB OPEN-LABEL STUDY OF THE SAFETY AND PHARMACOKINETICS OF MEHD7945A IN COMBINATION WITH EITHER CISPLATIN AND 5-FU OR PACLITAXEL AND CARBOPLATIN IN PATIENTS WITH RECURRENT/METASTATIC SQUAMOUS CELL CARCINOMA OF THE HEAD AND NECK. Sponsor Protocol No. GO28909. WIRB Protocol No. 20131256
Jimeno, Antonio13-2170
A PHASE II, MULTICENTER, SINGLE-ARM STUDY OF MPDL3280A IN PATIENTS WITH PD-L1-POSITIVE LOCALLY ADVANCED OR METASTATIC NON-SMALL CELL LUNG CANCER. Sponsor Protocol No. GO28625. WIRB Protocol No. 20130654
Camidge, David13-2173
A Multi-Center, Dose Finding, Open Label, Phase 1 Study of RX-5902 in Subjects with Advanced or Metastatic Solid Tumors. Sponsor Protocol No. RX-5902-P1-01. WIRB Protocol No. 20131320
Eckhardt, Sue13-2176
A Phase 3, Randomized, Double-Blind Study of Nivolumab Monotherapy or Nivolumab Combined with ipilimumab Versus Ipilimumab Monotherapy in Subjects with Previously Untreated Unresectable or Metastatic Melanoma. Sponsor Protocol No. CA209067. WIRB Protocol No. 20130618
Gonzalez, Rene13-2193
A Double-Blind, Placebo-Controlled, Single Ascending Intravenous Infusion Study of rHIgM22 in Patients with Multiple Sclerosis. Sponsor Protocol No. IM22-MS-1004. WIRB Protocol No. 20130406
Vollmer, Timothy13-2203
A multinational, multicenter, randomized, double-blind, parallel-group, placebo-controlled study followed by an active treatment period, to evaluate the efficacy, safety and tolerability of two doses of oral administration of laquinimod (0.6 mg/day or 1.2 mg/day) in subjects with relapsing remitting multiple sclerosis (RRMS) Sponsor Protocol No. LAQ-MS-305 (CONCERTO). WIRB Protocol No. 20130631
Vollmer, Timothy13-2209
A Phase 3, Multicenter, Double-Blind, Placebo-Controlled, Single-Treatment Efficacy and Safety Study of MYOBLOC® (Part A) Followed by Open-Label, Multiple-Treatment with MYOBLOC® (Part B) in the Treatment of Troublesome Sialorrhea in Adult Subjects. Sponsor Protocol No. SN-SIAL-301. WIRB Protocol No. 20131152
Klepitskaya, Olga13-2237
Evaluation of Bimatoprost 0.01% and Bimatoprost 0.03% in Patients with Glaucoma or Ocular Hypertension. Sponsor Protocol No. 192024-081. WIRB Protocol No. 20131409
Kahook, Malik13-2240
A Phase 1/2, First-In-Human, Double-Masked, Placebo-Controlled, Dose-Escalation Study Evaluating the Safety, Tolerability, and Efficacy of RU-101 Ophthalmic Solution in Patients with Severe Dry Eye. Sponsor Protocol No. RU-101-C001. WIRB Protocol No. 20131219
Davidson, Richard13-2241
A Multicenter, Open-Label, Extension Study to Evaluate the Long-Term Safety and Efficacy of BIIB019, Daclizumab High Yield Process (DAC HYP), Monotherapy in Subjects With Multiple Sclerosis Who Have Completed Study 205MS301. Sponsor Protocol No. 205MS303. WIRB Protocol No. 20131532
Miravalle, Augusto13-2243
A RANDOMIZED, DOUBLE-BLIND, PLACEBO-CONTROLLED, DOSE-RANGING, MULTICENTER STUDY TO ASSESS THE EFFICACY AND SAFETY OF RIFAXIMIN SOLUBLE SOLID DISPERSION (SSD) TABLETS FOR THE PREVENTION OF COMPLICATIONS IN SUBJECTS WITH EARLY DECOMPENSATED LIVER CIRRHOSIS. Sponsor Protocol No. RNLC2131. WIRB Protocol No. 20131309
Forman, Lisa13-2245
A Follow-up Study to Assess Resistance and Durability of Response to AbbVie Direct-Acting Antiviral Agent (DAA) Therapy in Subjects Who Participated in Phase 2 or 3 Clinical Studies for the Treatment of Chronic Hepatitis C Virus (HCV) Infection. Sponsor Protocol No. M13-102. WIRB Protocol No. 20131190
Everson, Greg13-2249
A Multicenter, Open-label BMN 110 US Expanded Access Program (BMN 110 US EAP) to Provide BMN 110 to Patients Diagnosed with MPS IVA. Sponsor Protocol No. 110-503. WIRB Protocol No. 20130460
Thomas, Janet13-2262
Clinical Outcomes Assessment of the MitraClip Percutaneous Therapy for Extremely High Surgical Risk Patients (The COAPT Trial). Sponsor Protocol No. 11-512. WIRB Protocol No. 20120840
Brieke, Andreas13-2266
A Phase 2, Multicenter, Open-Label STudy to Investigate the Safety and Efficacy of Sofosbuvir/Ledipasvir Fixed-Dose Combination + Ribavirin Administered in Subjects Infected with Chronic HCV who have Advanced Liver Disease or are Post-Liver Transplant. Sponsor Protocol No. GS-US-337-0123. WIRB Protocol No. 20131329
Everson, Greg13-2272
A multicenter, randomized, double-blind, parallel-group, placebo-controlled variable treatment duration study evaluating the efficacy and safety of Siponimod (BAF312) in patients with secondary progressive multiple sclerosis. Sponsor Protocol No. CBAF312A2304. WIRB Protocol No. 20130508
Corboy, John13-2286
AN OPEN-LABEL, MULTICENTER, FOLLOW-UP STUDY TO EVALUATE THE LONG-TERM SAFETY AND EFFICACY OF BRIVARACETAM USED AS ADJUNCTIVE TREATMENT IN SUBJECTS AGED 16 YEARS OR OLDER WITH EPILEPSY. Sponsor Protocol No. 2010-020345-27. WIRB Protocol No. 20101907
Strom, Laura13-2308