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Clinical Trials

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You can search for specific diseases or conditions in our Clinical Trials list (the page takes a few seconds to load due to the quantity of trials).

Page through all School of Medicine clinical and research trials below, or click here to look for specific types of trials.
(It will take a few seconds to load) There are two categories: 

  • Detailed Trial Descriptions, submitted by researchers, includes trial specifics and contact information.

  • Additional Clinical Trials, which include basic study details. To contact the researcher either Google the PI (primary investigator) name or use our campus directory.

If you are a researcher seeking volunteers and your study is not posted, please submit your Web ad here.  

Detailed Trial Descriptions

 Results From Research and Clinical Trials : Selected site
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COMIRB Approved Advertisement TitleStudy GoalsEligibility CriteriaDate Posted
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Type 2 Diabetes and Exercise Research Study
To research the effects of an investigational drug on exercise capacity and blood vessel function​.​
Person 30-60 with Type 2 diabetes who exercise vigorously less than one hour per week and have normal blood pressure. Must not have smoked for at least one year and have a BMI between 25-39.9.
7/28/2014
Volunteers with Chronic Kidney Disease needed for a Uric Acid Lowering Research Study
To understand the effect of lowering serum uric acid levels on vascular function in individuals with CKD by comparing Allopurinol therapy and a placebo.
Persons 18+ with moderate chronic kidney disease (CKD stage III) with estimated glomerular filtration rates  between 30-60 mL/min/1.73m2
7/28/2014
Are you a woman between the ages of 40 & 52
To study the effects of medication on perimenopausal symptoms.​
Women 40-52 who have regular periods and any hot flashes, cyclical bloating, mood changes, headaches or trouble sleeping
7/28/2014
Research Study: "Anxiety Risk in Teens"
To learn more about risk factors for anxiety in adolescents with cyclic vomiting syndrome.
Adolescents 13-18 who have been diagnosed with either an anxiety disorder or cyclic vomiting syndrome
7/28/2014
Are you interested in learning about how your breast milk helps your baby grow?
To find out how maternal size and diabetes status affect her breast milk To find out what unique parts of breast milk may affect how infants grow. To learn how to ensure infants receive the best nutrition possible
Women 20-35 who are at least 28 weeks into their pregnancy and planning on exclusively breastfeeding their infant for at least 4 months and delivering at University of Colorado Hospital.
7/28/2014
Free Family Therapy for Youth with Mood Problems
Helping youth and their families understand and cope with mood swings, develop plans for preventing moods from getting worse, communicate more effectively and solve family problems
Youth between 9-17 who has recently had significant mood swings, has at least one parent with bipolar disorder and does not abuse alcohol or substances. Must agree not to participate in family therapy with another provider for the first year.
7/28/2014
Genital Herpes?
This study will look at the body's immune response (how the body fights infection) to the onset of genital herpes.  1-2 study visits for blood draws over the course of 3 months.
18+ years of age; have developed an outbreak of genital herpes within the last 10 days.
7/28/2014
Seeking Children Ages 3 to 17 with NO History of Allergies, Eczema or Asthma
The goal of this study is to determine why some individuals with atopic dermatitis are at increased risk for skin infections.
Between the ages of 3-17 No history of allergies, eczema or asthma
7/28/2014
Induction of Labor at 39 Weeks Pregnant versus Expectant Management
Pregnant women are invited to participate in a research study which plans to learn more about whether coming to the hospital and having your labor started with medicine (ie., labor induction) at 39 weeks of pregnancy can improve the baby's health at birth when compared with waiting for labor to start on its own.
First pregnancy (no previous pregnancy beyond 20 weeks) Single baby (not twins or triplets) Planning to deliver vaginally and are at least 34 weeks pregnant Plan to deliver at University of Colorado Hospital or Denver Health Hospital
7/28/2014
Pregnant Participants Needed: A Phase II, Multicenter, Randomized, Observer-Blind, Controlled Study to Evaluate Safety and Immunogenicity of a Trivalent Group B Streptococcus (GBS) Vaccine in Healthy Pregnant Women
Pregnant women are invited to participate in a research study which plans to learn about antibody (substance produced by the body to fight disease) levels in mothers and infants whose mothers have received the GBS vaccine between 24-34 6/7 weeks of their current pregnancy.  the study will also look at antibody levels in mother's breast milk.
Healthy pregnant woman 18-40 years of age 24 0/7 through 34 6/7 weeks pregnant Planning to breastfeed for at least 90 days after delivery Plan to deliver at University of Colorado Hospital
7/28/2014
Healthy Volunteers Needed
The Department of Neurology is looking for healthy volunteers to participate in a research study examining blinking and spasms in people with Blepharospam compared to healthy controls
- Between the ages of 50-80 - Must not have any metal in your body - In good general health
7/28/2014
Healthy Volunteers Needed for a research study of drug levels in blood and hair.
This study plans to learn more about how tenofovir and emtricitabine (Truvada) build up in cells in blood and hair. Participation will include two 12 week dosing periods separated by a 12 week washout period (total duration is 36 weeks). Eligible participants will be given the supply of medications for the study.
Subject is age 18 to 50 years Subject is ambulatory Subject is able to comply with directly observed dosing procedures, including use of audio-visual streaming technology Subject is able to give informed consent Subject has a minimum scalp hair length of 2 cm in the occipital region. Subject is NOT pregnant, planning to become pregnant, or currently breastfeeding Subject is low risk for HIV-1 infection Subject does NOT have any active psychiatric illness(es), social condition(s), or alcohol/drug abuse Subject does NOT have history of non-traumatic, pathologic bone fractures Subject does NOT have any medical conditions that alter red blood cell kinetics Subject does NOT have any uncontrolled medical conditions that would interfere with the study conditions Subject does NOT have contraindicated concomitant medications
7/28/2014
Do you have Parkinson's Disease?
To explore the effects of different doses of endurance exercise in people with PD.​
Persons 40-80 who have been diagnosed with Parkinson's Disease and are not yet taking medication or plant to start medication within the next 6 months. You must be willing to begin the exercise program immediately or after a delay of 6 months and willing to do aerobic exercise on a treadmill.
7/25/2014
Do you have Atopic Dermatitis (Eczema)?
To study eczema
Males and Females between 3 and 80 who have atopic dermatitis or males and females between 8 months and 80 who have a history of, or an active case of eczema hereticum (wide-spread herpes skin infection along with atopic dermatitis.
7/25/2014
Better Control of Type 2 Diabetes May Decrease Your Risk for Cardiovascular Disease.
To look at the use of an extended release formula of Exenatide compared to a placebo to maintain normal glucose levels. Ultimately to see better control of diabetes and a decrease in cardiovascular disease events.​
Person 18+ with Type 2 Diabetes and take no more than 2 diabetes medications with stale doses for the last 3 months. Must not have a planned or anticipated revascularization procedure, but may have a history of cardiovascular disease and must see your primary care physician at least twice a year.
7/25/2014
Are you a Non-smoking Adult between the ages of 45 and 85?
We are interested in learning more about smoking related lung disease, and need healthy non-smoking participants.
45-85 years old Non-Hispanic White or African American No smoking history No evidence of lung disease
7/25/2014
Influenza Study
Doctors at the National Institutes of Health are conducting a research study (IRC-004) to investigate whether treating the flu decreases the amount of virus we can detect in your nose, and to understand whether the change in the amount of virus is associated with changes in your symptoms.
Volunteers may be male or female and must: -be at least 18 years old -have a history of an influenza-like illness -have an onset of illness within the past 48 hours -test positive for influenza
7/25/2014
Alterations in Lung Microbiome in Acute and Chronic HIV Infection
This is a prospective, observational cohort study. Three groups (A1, A2, and B) will be enrolled in parallel.
-Men and women >/= 18 years. -Willing to follow all research requirements -Willing to provide written informed consent -Group A1- acute HIV infection defined as a high risk HIV exposure within the prior 30 days, or recent HIV-1 seroconversion defined as those with a high risk HIV-1 exposure -Group A2- healthy controls: HIV-1 seronegative with no high risk HIV-1 exposure in the prior 30 days and no chronic medical illness -Group B- HIV-1 infection diagnosed by a previous positive antibody or PCR test have been recommended to initiate HAART by their health care provider You should not be in this study if you are a pregnant or planning to become pregnant.
7/25/2014
Has your child been diagnosed with generalized anxiety disorder?
to study sleep and brain activity
• between the ages of 12 & 18 • diagnosed with GAD OR • not diagnosed with any psychological disorders AND who are • right-handed • without orthodontic braces • not taking sleep medications
7/25/2014
Volunteers needed to Participate in a Research Study about Rheumatoid Arthritis
The purpose of this study is to learn more about how rheumatoid arthritis develops by studying people who do not have rheumatoid arthritis. Your participation in this study will help us determine if certain genetic and environmental factors affect the chances of developing RA-related autoantibodies in absence of rheumatoid arthritis.
You may be eligible to participate in the study if: -You are at least 18 years old -You do NOT have Rheumatoid Arthritis (RA)
7/25/2014
Restoring Insulin Secretion (RISE)
The Children’s Hospital Colorado Clinical Translational Research Center and the National Institutes of Health are conducting a study. This study is aimed at testing whether early treatment is beneficial to kids with early type 2 diabetes and kids at high risk of diabetes.
10-19 years of age, Pubertal, Overweight, Fasting glucose: >90 mg/dl; Impaired glucose tolerance: >140 mg/dl; Pre-diabetes or diagnosed with diabetes for less than 6 months; Metformin
7/25/2014
Participate in a Research Study at the University of Colorado. UC Denver is Conducting a Study on Back Pain and Spinal Manipulation at the Anschutz Medical Campus
To study muscle activity during chiropractic spinal manipulations
1) 18-55 years of age 2) Male 3) Must have low back pain
7/25/2014
Have you experienced a preterm birth?
If you participate, the information we learn from you will help us better understand how and why 1 out of 10 pregnancies in the US end in preterm birth.
1. Women ages 18-45 years old 2. willing to meet for 1-2 hours in a focus group setting 3. a mother of a baby who was born more than 3 weeks before your due date
7/25/2014
Do You Smoke?
To figure out how these lung substances work in people who drink too much alcohol, who usually smoke, compared to those who do not drink heavily, but who smoke.
Smoking and nonsmoking males
7/25/2014
Parents or Legal Guardians of Children with Disabilities
Assistive Technology Partners, University of Colorado, Anschutz Medical Campus, is performing a study investigating the impact Socially Assistive Robotics has on motor, communication and cognitive skills of children with disabilities.
Children between the ages of 18 months to 5 years of age Have Significant motor and communication disabilities/delays NOT been diagnosed with blindness or deafness They are without a seizure disorder or with a well-controlled seizure disorder They have been on stable medication regime for the past 12 weeks, if they are currently taking medication.
7/25/2014
Participants with Chronic Kidney Disease and Vitamin D Deficiency Needed for a Research Study
This study will examine whether nutritional or active vitamin D supplementation will improve blood vessel function​.
Person 18-80 with chronic kidney disease stage 3B or 4 (estimated GFR 44-15 m;/min) with a vitamin D deficiency or insufficiency.  Women must not be pregnant or breastfeeding.
7/24/2014
Trouble Sleeping?
Study the effects of two different study drugs, one or two non-drug interventions and/or a combination of both to treat insomnia.
Persons 21+ who have trouble falling or staying asleep at night.
7/24/2014
Give Us a Hand
To better understand Multiple Sclerosis in children and teens.
Between the ages of 3-20 AND have Multiple Sclerosis diagnosed before 18 OR Do not have MS
7/24/2014
Are you an African American with asthma?
 We are studying why some African American people have trouble with their asthma despite taking asthma medications.
 Children age 5-17 and non-smoking Adults age18 and older who have asthma symptoms despite asthma treatment • African American ancestry (have at least one    African American grandparent)
7/24/2014
Seeking healthy persons for testing an investigational drug for mental illness
Single administration under medical supervision. Compensation provided.
Healthy male and female adults, 18-50 years old with no previous or current mental illness. No drug use. Nonsmokers. If female, willing to use birth control.
7/24/2014

​Additional Clinical Trails

 Results From Research : Selected site
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A RANDOMIZED PHASE II CHEMOPREVENTION STUDY OF ILOPROST VERSUS PLACEBO IN PATIENTS AT HIGH RISK FOR LUNG CANCER
Keith, Robert01-279
A STUDY OF THE EFFECTIVENESS AND TOLERABILITY OF WEEKLY RIFAPENTINE/ISONIAZID FOR THREE MONTHS VERSUS DAILY ISONIAZID FOR NINE MONTHS FOR THE TREATMENT OF LATENT TUBERCULOSIS INFECTION [TBTC STUDY 26]
Gardner, Edward01-284
CHOLESTEROL AND ANTIOXIDANT TREATMENT IN PATIENTS WITH THE SMITH-LEMLI-OPITZ SYNDROME (SLOS)
Elias, Ellen01-410
A PHASE II STUDY OF ADJUVANT STI571 (GLEEVEC) THERAPY IN PATIENTS FOLLOWING COMPLETELY RESECTED HIGH-RISK PRIMARY GASTROINTESTINAL STROMAL TUMOR (GIST)
McCarter, Martin01-879
ANBL0032 PHASE III RANDOMIZED STUDY OF CHIMERIC ANTIBODY 14.18 (CH 14.18) IN HIGH RISK NEUROBLASTOMA FOLLOWING MYELOABLATIVE THERAPY AND AUTOLOGOUS STEM CELL RESCUE
Greffe, Brian01-932
DIABETES PREVENTION PROGRAM OUTCOMES STUDY (DPPOS)
Dabelea, Dana02-498
ACOSOG Z9001: A PHASE III RANDOMIZED DOUBLE-BLIND STUDY OF ADJUVANT STI571 (GLEEVEC) VERSUS PLACEBO IN PATIENTS FOLLOWING THE RESECTION OF PRIMARY GASTROINTESTINAL STROMAL TUMOR (GIST)
McCarter, Martin02-607
EFFICACY OF AGGRESSIVE RENIN-ANGIOTENSIN-ALDOSTERONE AXIS BLOCKADE IN PREVENTING/SLOWING RENAL FUNCTION DECLINE IN ADPKD
Schrier, Robert02-744
RANDOMIZED EVALUATION OF RECURRENT STROKE COMPARING PFO CLOSURE TO ESTABLISHED CURRENT STANDARD OF CARE TREATMENT - RESPECT TRIAL
Anderson, Clark02-805
A RANDOMIZED, DOUBLE-BLIND, PLACEBO-CONTROLLED, MULTICENTER PHASE III STUDY COMPARING GW572016 AND LETROZOLE VERSUS LETROZOLE IN SUBJECTS WITH ESTROGEN/PROGESTERONE RECEPTOR-POSITIVE ADVANCED OR METASTATIC BREAST CANCER (EGF 30008).
Elias, Anthony03-1030
A CONTINUATION PROTOCOL FOR PI-88 IN PATIENTS WITH ADVANCED MALIGNANCIES
Eckhardt, Sue03-1250
AALL0031 A CHILDREN'S ONCOLOGY GROUP PILOT STUDY FOR THE TREATMENT OF VERY HIGH RISK ACUTE LYMPHOBLASTIC LEUKEMIA IN CHILDREN AND ADOLESCENTS
Giller, Roger03-239
IMPAACT P1026s: Pharmacokinetic Properties of Antiretroviral and Related Drugs During Pregnancy and Postpartum, Version 8.0
McFarland, Elizabeth03-546
PROSPECTIVE MULTICENTER EVALUATION OF THE DURATION OF THERAPY FOR THROMBOSIS IN CHILDREN
Wang, Michael03-585
TREATMENT OPTIONS FOR TYPE 2 DIABETES IN ADOLESCENTS AND YOUTH
Zeitler, Philip03-595
COLORECTAL CHEMOPREVENTION WITH CALCIUM AND VITAMIN D (THE VITAMIN D/CALCIUM POLYP PREVENTION STUDY)
Ahnen, Dennis03-993
CLINICAL CORRELATION AND COST ANALYSIS OF SICKLE CELL PATIENTS UNDERGOING CHRONIC ERYTHROCYTAPHERESES.
Hassell, Kathryn04-0005
A PHASE II MULTICENTER STUDY TO EVALUATE THE EFFICACY AND SAFETY OF 500 MG OF FULVESTRANT (FASLODEX) AS A FIRST LINE HORMONAL TREATMENT IN POSTMENOPAUSAL WOMEN WITH HORMONE RECEPTOR POSITIVE METASTATIC BREAST CANCER.
Borges, Virginia04-0303
Use Of 3,4-Diaminopyridine (3,4-Dap)In The Treatment Of Lambert-Eaton Syndrome (Lems)
Ringel, Steven04-0567
ACNS0331: A STUDY EVALUATING LIMITED TARGET VOLUME BOOST IRRADIATION AND REDUCED DOSE CRANIOSPINAL RADIOTHERAPY (18.00 GY) AND CHEMOTHERAPY IN CHILDREN WITH NEWLY DIAGNOSED STANDARD RISK MEDULLOBLASTOMA: A PHASE III DOUBLE RANDOMIZED TRIAL
Foreman, Nicholas04-0625
DOUBLE-BLIND TRIAL OF CHOLINE DURING PREGNANCY AND RISK FOR SCHIZOPHRENIA
Ross, Randal04-0678
A STUDY OF THE EVALVE CARDIOVASCULAR VALVE REPAIR SYSTEM (CVRS) ENDOVASCULAR VALVE EDGE-TO-EDGE REPAIR STUDY
Carroll, John04-0831
INSULIN RESISTANCE INTERVENTION AFTER STROKE (IRIS) TRIAL
Hughes, Richard04-0855
RTOG 0234 - A PHASE II RANDOMIZED TRIAL OF SURGERY FOLLOWED BY CHEMORADIOTHERAPY PLUS C225 (CETUXIMAB) FOR ADVANCED SQUAMOUS CELL CARCINOMA OF THE HEAD AND NECK
Rabinovitch, Rachel04-0991
BELATACEPT EVALUATION OF NEPHROPROTECTION AND EFFICACY AS FIRST-LINE IMMUNOSUPPRESSION TRIAL-EXTENDED CRITERIA DONORS (BENEFIT EXT) PROTOCOL #IM103027
Chan, Laurence05-0292
A RANDOMIZED, DOUBLE-BLINDED, PLACEBO-CONTROLLED TRIAL OF CORTICOSTEROID THERAPY FOLLOWING PORTOENTEROSTOMY IN INFANTS WITH BILIARY ATRESIA
Sokol, Ronald05-0407
EFFECT OF STATIN THERAPY ON DISEASE PROGRESSION IN CHILDREN WITH ADPKD
Cadnapaphornchai, Melissa05-0704
A PHASE III DOUBLE-BLIND, RANDOMIZED, CONTROLLED STUDY TO EVALUATE THE SAFETY, IMMUNOGENICITY AND EFFICACY OF GLAXOSMITHKLINE BIOLOGICALS' HPV-16/18 VLP/ASO4 VACCINE ADMINISTERED INTRAMUSCULARY ACCORDING TO A THREE-DOSE SCHEDULE (0, 1, 6 MONTH) IN HEALTHY ADULT FEMALE SUBJECTS AGED 26 YEARS AND ABOVE. STUDY NUMBER 104820 (HPV-015)
Levin, Myron05-0853
GOG-0218 A PHASE III TRIAL OF CARBOPLATIN AND PACLITAXEL PLUS PLACEBO VERSUS CARBOPLATIN AND PACLITAXEL PLUS CONCURRENT BEVACIZUMAB (NSC # 704865, IND # 113912) FOLLOWED BY PLACEBO, VERSUS CARBOPLATIN AND PACLITAXEL PLUS CONCURRENT AND EXTENDED BEVACIZUMAB, IN WOMEN WITH NEWLY DIAGNOSED, PREVIOUSLY UNTREATED, STAGE III OR IV, EPITHELIAL OVARIAN, PRIMARY PERITONEAL OR FALLOPIAN TUBE CANCER
Davidson, Susan05-0874
ADVL04P2, A FEASIBILITY PILOT AND PHASE 2 STUDY OF CHEMOIMMUNOTHERAPY WITH EPRATUZUMAB (IND# 12034) FOR CHILDREN WITH RELAPSED CD22-POSITIVE ACUTE LYMPHOBLASTIC LEUKEMIA (ALL)
Gore, Lia05-0913