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Clinical Trials

Volunteer to Be Part of a Research Study

Page through all School of Medicine clinical and research trials below. There are two categories:

  • Detailed Trial Descriptions, submitted by researchers, includes trial specifics and contact information.

  • Additional Clinical Trials, which include basic study details. To contact the researcher either Google the PI (primary investigator) name or use our campus directory.

If you are a researcher seeking volunteers and your study is not posted, please
submit your Web ad here.

Detailed Trial Descriptions

 Results From Research and Clinical Trials : Selected site
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COMIRB Approved Advertisement TitleStudy GoalsEligibility CriteriaDate PostedCategory
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Are you interested in learning about how your breast milk helps your baby grow?
To find out how maternal size and diabetes status affect her breast milk To find out what unique parts of breast milk may affect how infants grow. To learn how to ensure infants receive the best nutrition possible
Women 20-35 with type 1, type 2,or gestational diabetes who are at least 28 weeks into their pregnancy and planning on exclusively breastfeeding their infant for at least 4 months and delivering at University of Colorado Hospital.
Free Family Therapy for Youth with Mood Problems
Helping youth and their families understand and cope with mood swings, develop plans for preventing moods from getting worse, communicate more effectively and solve family problems
  • Youth between 9-17 who has recently had significant mood swings, has at least one parent with bipolar disorder and does not abuse alcohol or substances. 
  • Must agree not to participate in family therapy with another provider for the first year.
MS Volunteers Needed for Research Study
Looking to see if there is a cognitive improvement with the treatment of oral estriol as compared to oral placebo
We are looking for: • Women 18-50 years old • Diagnosed with definite relapsing-remitting, secondary-progressive multiple sclerosis or primary-progressive multiple sclerosis • MS disease duration of 15 years or less • On stable dose of standard MS treatment with Copaxone®, Betaseron® (or Extavia®), Rebif®,Avonex®, Gilenya®, Aubagio®, Tecfidera®, or no treatment ----You are not eligible for the study if you are pregnant, breast-feeding, smoke, or have other serious medical conditions.
Genital Herpes?
This study will look at the body's immune response (how the body fights infection) to the onset of genital herpes.  1-2 study visits for blood draws over the course of 3 months.
  • 18+ years of age
  • Have developed an outbreak of genital herpes within the last 10 days.
The Role of Gut Bacteria in the Development of Type 1 Diabetes.
The goal of the research is to better understand the role bacteria that live in the intestine in the development of type 1 diabetes
  • Patients diagnosed with type 1 diabetes in the last 6 months 
  • Subjects with islet autoantibodies 
  • Subjects who do not have islet antibodies and are first-degree relatives of patients with diabetes or subjects with islet antibodies
  • 1-45 years of age
Are you interested in participating in a research study to help us learn more about where the fat tissue in your body originates?
To understand if some fat cells (adipocytes) may originally come from cells in the bone marrow. Understanding the origin of fat cells is important because it may help to determine the health of fat cells and why fat that is stored in some places of your body is more ‘unhealthy’ than other fat.
Men and women: Between the ages of 18 and 75 years AND Had an allogeneic hematopoietic stem cell transplant at least 6 months ago –OR– Have chronic phase chronic myeloid leukemia.
9/18/2017Nutritional and Metabolic Diseases
Are you looking for an alternative treatment for your insomnia?
The purpose of this pilot study is to learn more about treatments for insomnia. Long-term use and dependence on controlled substance sleep medications (also known as “hypnotics”) is a common issue and is a less than ideal way to treat insomnia. Stopping the use of sleeping pills and trying other treatments for insomnia is difficult for many insomnia patients. Treatments combining supervised medication tapering (SMT), which is a gradual reduction of medication use, and cognitive behavioral insomnia therapy for insomnia (CBT-I), which is a form of talk therapy that helps a person learn to better handle behaviors, habits and thoughts that lead to sleeping problems., help some who wish to stop using sleep aids, but many individuals who complete these treatments do not give up their sleep aids altogether. This project will look at how to best help insomnia patients transitioning from using sleep aids to other treatment options for their insomnia.
• Adults 21 years of age and older who have chronic insomnia • Current medication use for treatment of chronic insomnia (over one year) • Desire to stop medication use
9/18/2017Behaviors and Mental Disorders
Participants needed for a study with Diabetes and couples health behaviors
This is a couples-based approach for increasing physical activity among adults with type 2 diabetes. Increasing physical activity has been shown to have great health benefits for managing diabetes.
One partner (or both) has Type 2 Diabetes One partner (or both) has been sedentary Each member is willing to increase their current level of physical activity Between the ages of 30 and 69
9/18/2017Nutritional and Metabolic Diseases
Healthy men needed for cardiovascular study
The purpose of this research is to study how low testosterone affects the health of the heart and arteries in men.
- Men  50-75 years old, in general good health - No history of cancer, diabetes or heart disease - Non-smokers - Not currently taking medications to treat high blood pressure, cholesterol, taking testosterone therapy or exercising vigorously more than 2 days per week
9/18/2017Heart and Blood Diseases
Participants ages 7-65 undergoing upper endoscopy needed for Research Study
Determine the efficacy of the EnteroTracker String Test (EST)for monitoring inflammation in the esophagus. Compare analysis of the EST to biopsies taken during an upper endoscopy.
Diagnosed EOE or patients with symptoms of abdominal pain, vomiting, growth delay or malabsorption with an Upper Endoscopy scheduled at either Children’s Hospital Colorado or the University of Colorado Hospital. Other Exclusion criteria may apply.
9/18/2017Digestive System Diseases
Volunteers wanted for Asthma Research Study
Researchers at the University of Colorado is seeking volunteers for an asthma research study to learn how weight and dietary supplement typically found in watermelon (Citrulline) may relate to asthma.
You may be eligible to participate if you:  Are between the ages of 18 and 60 years old  Have been diagnosed with asthma by a healthcare provider  Are overweight (a body mass index of 30 or greater)  Are not pregnant, breastfeeding, or planning to get pregnant in the next 6 months  Do not currently smoke  Have not smoked more than 1 pack a day over the last 10 years
9/18/2017Respiratory Tract (Lung and Bronchial) Diseases
Breast Cancer. Genetic Testing and Health Insurance: A Research Study
The goal of this research study is to understand how breast cancer patients in Colorado are able to obtain genetic testing and how test results are used to make treatment decisions. We are interested in talking with all breast cancer patients and survivors diagnosed in Colorado
Are you a breast cancer patient or survivor? Were you diagnosed in 2009 or after? Were you diagnosed in Colorado? If you answered “YES” to all three questions, you are eligible. You do NOT have to have received genetic testing to be in this study!
9/18/2017Cancers and Other Neoplasms
Research on a new group intervention for pediatric autonomic dysfunction.
This research aims to evaluate a new group therapy intervention for youth with autonomic dysfunction and their parents.
Eligible families will have a teenager who is between 13 and 18 years old, has a diagnosis of autonomic dysfunction, dysautonomia, orthostatic intolerance, and/or POTS (postural orthostatic tachycardia syndrome), and has difficulty completing day-to-day activities like going to school, and/or has been experiencing anxiety or worries and/or low mood.
9/18/2017Behaviors and Mental Disorders
Balance After Baby Intervention
A research study at the University of Colorado to help women with gestational diabetes lose weight after pregnancy
You may qualify for this study if you:  Are at least 18 years old  Had GDM during your most recent pregnancy  Had no personal history of Type 1 or 2 diabetes  Your pre-pregnancy body mass index is between 18 and 50 kg/m2  Your 6 week postpartum body mass index is between 24 and 50 kg/m2 (>22 for Asians)  Have daily access to the internet
9/18/2017Nutritional and Metabolic Diseases
iPrEP: An Injectable PrEP Research Study
New products are being developed to help prevent HIV and YOU CAN HELP! iPrEP is looking for healthy men and transgender women who have sex with men to take part in a research study. Learn more about PrEP and a research study to develop new products to Prevent HIV.
IF YOU ARE: A healthy HIV-negative man or transgender woman A HIV-Negative Man or Transgender Woman 18 years of age or older  Available Weekdays
9/18/2017Immune System Diseases
Do you have Atopic Dermatitis (Eczema)?
To study eczema
Males and Females between 3 and 80 who have atopic dermatitis or males and females between 8 months and 80 who have a history of, or an active case of eczema hereticum (wide-spread herpes skin infection along with atopic dermatitis.
Type 2 Diabetes and Exercise Research Study
To research the effects of an investigational drug on exercise capacity and blood vessel function​.​
Person 30-60 with Type 2 diabetes who exercise vigorously less than one hour per week and have normal blood pressure. Must not have smoked for at least one year and have a BMI between 25-39.9.
Are you a Non-smoking Adult between the ages of 45 and 85?
We are interested in learning more about smoking related lung disease, and need healthy non-smoking participants.
45-85 years old Non-Hispanic White or African American No smoking history No evidence of lung disease
Volunteers needed to Participate in a Research Study about Rheumatoid Arthritis
The purpose of this study is to learn more about how rheumatoid arthritis develops by studying people who do not have rheumatoid arthritis. Your participation in this study will help us determine if certain genetic and environmental factors affect the chances of developing RA-related autoantibodies in absence of rheumatoid arthritis.
You may be eligible to participate in the study if: -You are at least 40 years old -You do NOT have Rheumatoid Arthritis (RA)
Restoring Insulin Secretion (RISE)
The Children’s Hospital Colorado Clinical Translational Research Center and the National Institutes of Health are conducting a study. This study is aimed at testing whether early treatment is beneficial to kids with early type 2 diabetes and kids at high risk of diabetes.
10-19 years of age, Pubertal, Overweight, Fasting glucose: >90 mg/dl; Impaired glucose tolerance: >140 mg/dl; Pre-diabetes or diagnosed with diabetes for less than 6 months; Metformin
Do You Smoke?
To figure out how these lung substances work in people who drink too much alcohol, who usually smoke, compared to those who do not drink heavily, but who smoke.
Smoking and nonsmoking males
Parents or Legal Guardians of Children with Disabilities
Assistive Technology Partners, University of Colorado, Anschutz Medical Campus, is performing a study investigating the impact Socially Assistive Robotics has on motor, communication and cognitive skills of children with disabilities.
Children between the ages of 18 months to 5 years of age Have Significant motor and communication disabilities/delays NOT been diagnosed with blindness or deafness They are without a seizure disorder or with a well-controlled seizure disorder They have been on stable medication regime for the past 12 weeks, if they are currently taking medication.
Help Us Learn About Schizophrenia!
Help us learn more about a new drug that may improve thinking and concentration in people with schizophrenia.
We are looking for: Male and female adults who smoke 18-50 years old No previous or current mental illness No drug use Willing to use nicotine patch during study hospital visit If female, willing to use birth control during the study
Research Trial Evaluating a New Drug in Psoriasis: Now Enrolling
The study will evaluate an investigational drug compared to a currently approved psoriasis medication. Your participation will provide valuable information to researchers seeking new and improved therapies. You will be given either Humira, placebo, or the investigational drug for up to 28 weeks, after which you may be switched over to the active drug depending on your response.
You may be eligible to participate if 18 years of age or older and have been diagnosed with moderate to severe plaque-type psoriasis for at least 6 months.
Do you have high blood pressure?
Study to help predict if blood pressure medications will work for you.
You may be eligible if you are an adult aged 30-80 with a diagnosis of uncontrolled essential hypertension. You must not have a history of end stage liver or renal disease, cannot be pregnant, and cannot be allergic to metoprolol.
9/15/2017Heart and Blood Diseases
Volunteers Needed for a Research Study about Rheumatoid Arthritis
The purpose of this study is to learn more about rheumatoid arthritis. Your participation in this study will help us determine if gum disease affects the chances of developing protein markers associated with rheumatoid arthritis.
1. You are at least 18 years old 2. You do NOT wear dentures 3. You do NOT take antibiotics prior to any dental work or cleaning 4. You HAVE rheumatoid arthritis diagnosed in the last 3 years OR you HAVE lupus or Sjogren’s syndrome diagnosed at any time in the past
9/15/2017Immune System Diseases
Healthy Females Needed
For brain imaging research study on how the brain works with we taste sweets or receive money. Your participation could help us to develop treatments and preventive measures for anorexia nervosa and obesity
Healthy females 16 to 35 who are right-handed, free of medication with no serious medical conditions, permanent metal implants or braces/retainers, and are at a healthy body weight.
9/15/2017--Select a Category--
The University of Colorado Denver School of Medicine is conducting a research study to learn more about an investigational vaccine to prevent C Difficile infection (C diff). C diff is a diarrheal disease that is often difficult to treat and get rid of, particularly in people who are at greater risk.
You may be eligible to participate if you: • Are age 50 or older, • Have never had C diff illness or vaccine • Have had one of the following: o Antibiotics in the last 12 weeks, OR o In the last 12 months – 2 nights hospital stay, OR 2 ER visits, OR 10 outpatient visits, AND o Can provide documentation of the above.
9/15/2017Bacterial and Fungal Diseases
Women with History of Pregnancy Induced High Blood Pressure Needed for Cardiovascular Research Study
The purpose of this study is to investigate how the menopause transition and the loss of estrogen impacts the health and function of the heart and arteries in women who developed high blood pressure during past pregnancies.
-Premenopausal women 18-55 years -Perimenopausal women 40-55 years -Postmenopausal women 45-70 years -Pregnancy history of any of the following: pregnancy-induced high blood pressure, preeclampsia, eclampsia, gestational high blood pressure -Nonsmokers -NOT currently taking birth control or hormone replacement therapy or exercising vigorously more than 2 days per week
9/15/2017Heart and Blood Diseases
Research Opportunity 18 - 50 years of age
The University of Colorado Denver School of Medicine is conducting a research study to learn more about the immune response to tuberculosis (TB).
You, or someone you know, may be eligible to participate if you: * Are age 18 - 50, in general good health * Received BCG vaccine as a child * Have lived most of your life in a developed country * Have not smoked for more than 10 years * Received tuberculosis vaccine (BCG) as a child in an area where TB was common (such as in Eastern Europe, Asia, or Africa), * Spent most of their life in a country where it was not common (such as Western Europe or the US)
9/15/2017Respiratory Tract (Lung and Bronchial) Diseases