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Clinical Trials

Volunteer to Be Part of a Research Study


You can search for specific diseases or conditions in our Clinical Trials list (the page takes a few seconds to load due to the quantity of trials).

Page through all School of Medicine clinical and research trials below, or click here to look for specific types of trials.
(It will take a few seconds to load) There are two categories: 

  • Detailed Trial Descriptions, submitted by researchers, includes trial specifics and contact information.

  • Additional Clinical Trials, which include basic study details. To contact the researcher either Google the PI (primary investigator) name or use our campus directory.

If you are a researcher seeking volunteers and your study is not posted, please submit your Web ad here.  

Detailed Trial Descriptions

 Results From Research and Clinical Trials : Selected site
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COMIRB Approved Advertisement TitleStudy GoalsEligibility CriteriaDate Posted
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Would you like to participate in a research study investigating how large body mass makes it more difficult to get pregnant?
To investigate how large body mass makes it more difficult to get pregnant.
Healthy Women ages 18-42 who have regular menstrual cycles and do not currently use hormones or are allergic to fish or seafood and who are willing to have frequent blood draws and collect urine samples at home.
4/22/2014
Learn BIOFEEDBACK, take charge of your asthma
To use Biofeedback to control asthma
Non-smoking adults with persistent asthma who have not taken inhaled steroid medication in the past 30 days.  wiling to test two different non-medication, biofeedback treatments.
4/22/2014
Cognitive Dysfunction in Parkinson's Disease
This research study plans to use simultaneous brain scans and memory tasks to see if stimulating certain areas of the brain improves thinking and memory. This is not a treatment study
Healthy males over 50 with Parkinson's disease on stable doses of medication and have no metal in the body (dental work may be ok).
4/22/2014
EFFECTS OF TESTOSTERONE THERAPY IN YOUNG ADOLESCENTS WITH KLINEFELTER SNDROME (47.XXY)
This study will study the effects of testosterone therapy on behavior, mood, problem solving, attention span, and motor skills in adolescent males with Klinefelter syndrome in early puberty. During this period in early puberty there is a lot of variability in how and when doctors start testosterone therapy. This study will evaluate if there are benefits to starting testosterone therapy in early puberty.
Participants with Klinefelter syndrome in early puberty (around age 10-15).
4/22/2014
Join a research study that helps you lose weight and become more fit!
Seeking volunteers for a research study testing muscle lipid metabolism and diabetes risk before and after a weight loss and exercise training intervention.
Pre-diabetic Age 30-60 BMI over 30 Male or female non-smoking
4/22/2014
Managing Celiac Disease May Be More Than a Gluten-free Diet
The CeliAction Study is a clinical research study designed to evaluate the safety and effectiveness of an investigational medication for people with celiac disease.
Diagnosed with celiac disease On a gluten-free diet for at least 11 months Have experienced at least one moderate or severe celiac symptom in the past month
4/22/2014
Are you interested in losing weight?
Volunteers needed for a research weight loss study to examine the neuronal and behavioral changes that occur with different weight loss interventions (weight loss surgery or diet).
- Are 21-65 years old - Have no metal in your body - Maintained your current weight for the last 6 months - Weigh 350 pounds or less - Have a body mass index of 35 or higher (check it out at http://nhlbisupport.com/bmi/)
4/22/2014
Are you interested in a supervised weight loss intervention?
Volunteers needed for a research weight loss study to examine the neuronal and behavioral changes that occur with different weight loss interventions.
- 21-65 years old - Non- smoker - Non- Diabetic - Exercise no more than 1 time a week - Maintained your current weight for the last 6 months - Have a body mass index of 30 -40 (check it out at http://nhlbisupport.com/bmi/
4/22/2014
Are you a Parkinson's patient not requiring symptomatic treatment with drugs?
This research study explores the effects of an FDA approved drug on Parkinson's disease.
Recently diagnosed Parkinson's patients who are not taking any drugs for symptomatic relief or are willing to go off drugs for the duration of the study with neurologist approval. We are also looking for healthy control participants.
4/22/2014
Healthy subjects needed for high altitude research study
For a research study on how intracranial pressure is related to acute mountain sickness
Between the ages of 18-40 years old - Do not smoke - Engage in regular physical exercise - Willing and able to engage in moderate physical activities in a simulated high altitude environment
4/22/2014
The Health Influences in Puberty "HIP" study
Research study about puberty and risk for type 2 diabetes
Healthy boy between 11 and 13 years of age Healthy girl between 9 and 11 years of age
4/22/2014
Type 2 Diabetes and Exercise Research Study
To research the effects of an investigational drug on exercise capacity and blood vessel function​.​
Person 30-60 with Type 2 diabetes who exercise vigorously less than one hour per week and have normal blood pressure. Must not have smoked for at least one year and have a BMI between 25-39.9.
4/21/2014
Volunteers with Chronic Kidney Disease needed for a Uric Acid Lowering Research Study
To understand the effect of lowering serum uric acid levels on vascular function in individuals with CKD by comparing Allopurinol therapy and a placebo.
Persons 18+ with moderate chronic kidney disease (CKD stage III) with estimated glomerular filtration rates  between 30-60 mL/min/1.73m2
4/21/2014
Are you a woman between the ages of 40 & 52
To study the effects of medication on perimenopausal symptoms.​
Women 40-52 who have regular periods and any hot flashes, cyclical bloating, mood changes, headaches or trouble sleeping
4/21/2014
Office Workers with Chronic Neck Pain Needed for Research Study
To identify pain processing responses and chronic stress levels in office workers with chronic neck pain.
Person who work at least 30 hours a week in an office setting that requires you to use a computer for most of the workday. You must have experienced neck pain for a least 3 month and not have had any surgical procedures of the neck or shoulder region.
4/21/2014
Research Study: "Anxiety Risk in Teens"
To learn more about risk factors for anxiety in adolescents with cyclic vomiting syndrome.
Adolescents 13-18 who have been diagnosed with either an anxiety disorder or cyclic vomiting syndrome
4/21/2014
Pilot Phase: A Randomized Trial of Fetal ECG ST Segment and T Wave Analysis as an Adjunct to Electronic Fetal Heart Rate Monitoring (STAN)
To use and understand the STAN monitor during labor and delivery.
Women who are 36 weeks pregnant or greater when in labor having a single baby (not twins or triplets) and are planning on delivering vaginally at University of Colorado Hospital.
4/21/2014
Are you interested in learning about how your breast milk helps your baby grow?
To find out how maternal size and diabetes status affect her breast milk To find out what unique parts of breast milk may affect how infants grow. To learn how to ensure infants receive the best nutrition possible
Women 20-35 who are at least 28 weeks into their pregnancy and planning on exclusively breastfeeding their infant for at least 4 months and delivering at University of Colorado Hospital.
4/21/2014
Free Family Therapy for Youth with Mood Problems
Helping youth and their families understand and cope with mood swings, develop plans for preventing moods from getting worse, communicate more effectively and solve family problems
Youth between 9-17 who has recently had significant mood swings, has at least one parent with bipolar disorder and does not abuse alcohol or substances. Must agree not to participate in family therapy with another provider for the first year.
4/21/2014
Genital Herpes?
This study will look at the body's immune response (how the body fights infection) to the onset of genital herpes.  1-2 study visits for blood draws over the course of 3 months.
18+ years of age; have developed an outbreak of genital herpes within the last 10 days.
4/21/2014
Do you have Parkinson's Disease?
To explore the effects of different doses of endurance exercise in people with PD.​
Persons 40-80 who have been diagnosed with Parkinson's Disease and are not yet taking medication or plant to start medication within the next 6 months. You must be willing to begin the exercise program immediately or after a delay of 6 months and willing to do aerobic exercise on a treadmill.
4/18/2014
Do you have Atopic Dermatitis (Eczema)?
To study eczema
Males and Females between 3 and 80 who have atopic dermatitis or males and females between 8 months and 80 who have a history of, or an active case of eczema hereticum (wide-spread herpes skin infection along with atopic dermatitis.
4/18/2014
Better Control of Type 2 Diabetes May Decrease Your Risk for Cardiovascular Disease.
To look at the use of an extended release formula of Exenatide compared to a placebo to maintain normal glucose levels. Ultimately to see better control of diabetes and a decrease in cardiovascular disease events.​
Person 18+ with Type 2 Diabetes and take no more than 2 diabetes medications with stale doses for the last 3 months. Must not have a planned or anticipated revascularization procedure, but may have a history of cardiovascular disease and must see your primary care physician at least twice a year.
4/18/2014
Are you a Non-smoking Adult between the ages of 45 and 85?
We are interested in learning more about smoking related lung disease, and need healthy non-smoking participants.
45-85 years old Non-Hispanic White or African American No smoking history No evidence of lung disease
4/18/2014
Influenza Study
Doctors at the National Institutes of Health are conducting a research study (IRC-004) to investigate whether treating the flu decreases the amount of virus we can detect in your nose, and to understand whether the change in the amount of virus is associated with changes in your symptoms.
Volunteers may be male or female and must: -be at least 18 years old -have a history of an influenza-like illness -have an onset of illness within the past 48 hours -test positive for influenza
4/18/2014
Alterations in Lung Microbiome in Acute and Chronic HIV Infection
This is a prospective, observational cohort study. Three groups (A1, A2, and B) will be enrolled in parallel.
-Men and women >/= 18 years. -Willing to follow all research requirements -Willing to provide written informed consent -Group A1- acute HIV infection defined as a high risk HIV exposure within the prior 30 days, or recent HIV-1 seroconversion defined as those with a high risk HIV-1 exposure -Group A2- healthy controls: HIV-1 seronegative with no high risk HIV-1 exposure in the prior 30 days and no chronic medical illness -Group B- HIV-1 infection diagnosed by a previous positive antibody or PCR test have been recommended to initiate HAART by their health care provider You should not be in this study if you are a pregnant or planning to become pregnant.
4/18/2014
Has your child been diagnosed with generalized anxiety disorder?
to study sleep and brain activity
• between the ages of 12 & 18 • diagnosed with GAD OR • not diagnosed with any psychological disorders AND who are • right-handed • without orthodontic braces • not taking sleep medications
4/18/2014
Volunteers needed to Participate in a Research Study about Rheumatoid Arthritis
The purpose of this study is to learn more about how rheumatoid arthritis develops by studying people who do not have rheumatoid arthritis. Your participation in this study will help us determine if certain genetic and environmental factors affect the chances of developing RA-related autoantibodies in absence of rheumatoid arthritis.
You may be eligible to participate in the study if: -You are at least 18 years old -You do NOT have Rheumatoid Arthritis (RA)
4/18/2014
Restoring Insulin Secretion (RISE)
The Children’s Hospital Colorado Clinical Translational Research Center and the National Institutes of Health are conducting a study. This study is aimed at testing whether early treatment is beneficial to kids with early type 2 diabetes and kids at high risk of diabetes.
10-19 years of age, Pubertal, Overweight, Fasting glucose: >90 mg/dl; Impaired glucose tolerance: >140 mg/dl; Pre-diabetes or diagnosed with diabetes for less than 6 months; Metformin
4/18/2014
Participate in a Research Study at the University of Colorado. UC Denver is Conducting a Study on Back Pain and Spinal Manipulation at the Anschutz Medical Campus
To study muscle activity during chiropractic spinal manipulations
1) 18-55 years of age 2) Male 3) Must have low back pain
4/18/2014

​Additional Clinical Trails

 Results From Research : Selected site
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Engineering Clinical Evaluation of Philips Medical's Modified CX50 with Revision MI 3 Software and Q-Station Software with new Release 9.0.Sponsor Protocol Philips Medical. WIRB Protocol No. 20110948
Salcedo, Ernesto11-0797
Adult Congenital Heart Disease Quality Enhancement Research Initiative (ACHD QuERI). Sponsor Protocol CHRC2011-ACHD001. WIRB Protocol No. 20111582
Kay, Joseph12-1161
The Targeting Acute Congestion with Tolvaptan in Congesting Heart Failure Study (Tactics-HF). WIRB Protocol No. 20121793
Shakar, Simon13-0112
ASPIRE Early Ablation Therapy for the Treatment of Ischemic Ventricular Tachycardia in Patients with Implantable Cardioverter Defibrillators. WIRB Protocol No.20121193
Tzou, Wendy13-0280
A PHASE 3, MULTICENTER, RANDOMIZED, OPEN-LABEL STUDY TO COMPARE THE EFFICACY AND SAFETY OF POMALIDOMIDE, BORTEZOMIB AND LOW-DOSE DEXAMETHASONE VERSUS BORTEZOMIB AND LOW-DOSE DEXAMETHASONE IN SUBJECTS WITH RELAPSED OR REFRACTORY MULTIPLE MYELOMA. Sponsor Protocol # CC-4047-MM-007. WIRB Protocol # 20121754
Smith, Clayton13-2056
Exhibit B-14 Specific Research Plan for Voyager 1.0. WIRB Protocol # 20131141
Salcedo, Ernesto13-2062
A Single-arm Study to Assess the Efficacy and Safety of Oral Rigosertib in Transfusion-dependent, Low or Intermediate-1, Myelodysplastic Syndrome Patients Based on the International Prognostic Scoring System. Sponsor Protocol # 09-07. WIRB Protocol # 20131128
Pollyea, Daniel13-2064
COMBI-AD: A phase III randomized double blind study of dabrafenib (GSK2118436) in COMBInation with trametinib (GSK1120212) versus two placebos in the ADjuvant treatment of high-risk BRAF V600 mutation-positive melanoma after surgical resection. Sponsor Protocol # BRF115532. WIRB Protocol # 20130566
Gonzalez, Rene13-2093
A PROSPECTIVE, RANDOMIZED, CONTROLLED, PARALLEL GROUPS, MULTICENTER POST-APPROVAL STUDY OF THE GLAUKOS® ISTENT® TRABECULAR MICRO-BYPASS STENT SYSTEM IN CONJUNCTION WITH CATARACT SURGERY. SPONSOR PROTOCOL # GTS100-PAS2. WIRB PROTOCOL # 20130739
Seibold, Leonard13-2098
A randomized, double blind, placebo-controlled, multicenter phase III study of regorafenib in patients with hepatocellular carcinoma (HCC) after sorafenib. Sponsor Protocol No. BAY 73-4506 / 15982. WIRB Protocol No. 20121899
Purcell, William13-2135
A Phase I Dose Escalation Open-Label Safety, Pharmacokinetic and Pharmacodynamic Study to Determine the Recommended Phase II Dose of GSK1120212 Dosed in Combination with GSK2141795. Sponsor Protocol No. TAC113886. WIRB Protocol No. 20130890
Gonzalez, Rene13-2146
A Double-Blind, Placebo-Controlled Evaluation of the Safety and Efficacy of Vilazodone in Adolescent Patients with Major Depressive Disorder. Sponsor Protocol No. VLZ-MD-21. WIRB Protocol No. 20130945
Wamboldt, Marianne13-2149
A Phase 2, Randomized, Multicenter Study of PEGPH20 (PEGylated Recombinant Human Hyaluronidase) Combined with nab-Paclitaxel Plus Gemcitabine Compared With nab-Paclitaxel Plus Gemcitabine in Subjects With Stage IV Previously Untreated Pancreatic Cancer. Sponsor Protocol No. HALO-109-202. WIRB Protocol No. 20130824
Weekes, Colin13-2161
A PHASE IB OPEN-LABEL STUDY OF THE SAFETY AND PHARMACOKINETICS OF MEHD7945A IN COMBINATION WITH EITHER CISPLATIN AND 5-FU OR PACLITAXEL AND CARBOPLATIN IN PATIENTS WITH RECURRENT/METASTATIC SQUAMOUS CELL CARCINOMA OF THE HEAD AND NECK. Sponsor Protocol No. GO28909. WIRB Protocol No. 20131256
Jimeno, Antonio13-2170
A PHASE II, MULTICENTER, SINGLE-ARM STUDY OF MPDL3280A IN PATIENTS WITH PD-L1-POSITIVE LOCALLY ADVANCED OR METASTATIC NON-SMALL CELL LUNG CANCER. Sponsor Protocol No. GO28625. WIRB Protocol No. 20130654
Camidge, David13-2173
A Multi-Center, Dose Finding, Open Label, Phase 1 Study of RX-5902 in Subjects with Advanced or Metastatic Solid Tumors. Sponsor Protocol No. RX-5902-P1-01. WIRB Protocol No. 20131320
Eckhardt, Sue13-2176
A Phase 3, Randomized, Double-Blind Study of Nivolumab Monotherapy or Nivolumab Combined with ipilimumab Versus Ipilimumab Monotherapy in Subjects with Previously Untreated Unresectable or Metastatic Melanoma. Sponsor Protocol No. CA209067. WIRB Protocol No. 20130618
Gonzalez, Rene13-2193
A Double-Blind, Placebo-Controlled, Single Ascending Intravenous Infusion Study of rHIgM22 in Patients with Multiple Sclerosis. Sponsor Protocol No. IM22-MS-1004. WIRB Protocol No. 20130406
Vollmer, Timothy13-2203
A multinational, multicenter, randomized, double-blind, parallel-group, placebo-controlled study followed by an active treatment period, to evaluate the efficacy, safety and tolerability of two doses of oral administration of laquinimod (0.6 mg/day or 1.2 mg/day) in subjects with relapsing remitting multiple sclerosis (RRMS) Sponsor Protocol No. LAQ-MS-305 (CONCERTO). WIRB Protocol No. 20130631
Vollmer, Timothy13-2209
A Phase 3, Multicenter, Double-Blind, Placebo-Controlled, Single-Treatment Efficacy and Safety Study of MYOBLOC® (Part A) Followed by Open-Label, Multiple-Treatment with MYOBLOC® (Part B) in the Treatment of Troublesome Sialorrhea in Adult Subjects. Sponsor Protocol No. SN-SIAL-301. WIRB Protocol No. 20131152
Klepitskaya, Olga13-2237
Evaluation of Bimatoprost 0.01% and Bimatoprost 0.03% in Patients with Glaucoma or Ocular Hypertension. Sponsor Protocol No. 192024-081. WIRB Protocol No. 20131409
Kahook, Malik13-2240
A Phase 1/2, First-In-Human, Double-Masked, Placebo-Controlled, Dose-Escalation Study Evaluating the Safety, Tolerability, and Efficacy of RU-101 Ophthalmic Solution in Patients with Severe Dry Eye. Sponsor Protocol No. RU-101-C001. WIRB Protocol No. 20131219
Davidson, Richard13-2241
A Multicenter, Open-Label, Extension Study to Evaluate the Long-Term Safety and Efficacy of BIIB019, Daclizumab High Yield Process (DAC HYP), Monotherapy in Subjects With Multiple Sclerosis Who Have Completed Study 205MS301. Sponsor Protocol No. 205MS303. WIRB Protocol No. 20131532
Miravalle, Augusto13-2243
A RANDOMIZED, DOUBLE-BLIND, PLACEBO-CONTROLLED, DOSE-RANGING, MULTICENTER STUDY TO ASSESS THE EFFICACY AND SAFETY OF RIFAXIMIN SOLUBLE SOLID DISPERSION (SSD) TABLETS FOR THE PREVENTION OF COMPLICATIONS IN SUBJECTS WITH EARLY DECOMPENSATED LIVER CIRRHOSIS. Sponsor Protocol No. RNLC2131. WIRB Protocol No. 20131309
Forman, Lisa13-2245
A Follow-up Study to Assess Resistance and Durability of Response to AbbVie Direct-Acting Antiviral Agent (DAA) Therapy in Subjects Who Participated in Phase 2 or 3 Clinical Studies for the Treatment of Chronic Hepatitis C Virus (HCV) Infection. Sponsor Protocol No. M13-102. WIRB Protocol No. 20131190
Everson, Greg13-2249
A Multicenter, Open-label BMN 110 US Expanded Access Program (BMN 110 US EAP) to Provide BMN 110 to Patients Diagnosed with MPS IVA. Sponsor Protocol No. 110-503. WIRB Protocol No. 20130460
Thomas, Janet13-2262
Clinical Outcomes Assessment of the MitraClip Percutaneous Therapy for Extremely High Surgical Risk Patients (The COAPT Trial). Sponsor Protocol No. 11-512. WIRB Protocol No. 20120840
Brieke, Andreas13-2266
A Phase 2, Multicenter, Open-Label STudy to Investigate the Safety and Efficacy of Sofosbuvir/Ledipasvir Fixed-Dose Combination + Ribavirin Administered in Subjects Infected with Chronic HCV who have Advanced Liver Disease or are Post-Liver Transplant. Sponsor Protocol No. GS-US-337-0123. WIRB Protocol No. 20131329
Everson, Greg13-2272
A multicenter, randomized, double-blind, parallel-group, placebo-controlled variable treatment duration study evaluating the efficacy and safety of Siponimod (BAF312) in patients with secondary progressive multiple sclerosis. Sponsor Protocol No. CBAF312A2304. WIRB Protocol No. 20130508
Corboy, John13-2286
AN OPEN-LABEL, MULTICENTER, FOLLOW-UP STUDY TO EVALUATE THE LONG-TERM SAFETY AND EFFICACY OF BRIVARACETAM USED AS ADJUNCTIVE TREATMENT IN SUBJECTS AGED 16 YEARS OR OLDER WITH EPILEPSY. Sponsor Protocol No. 2010-020345-27. WIRB Protocol No. 20101907
Strom, Laura13-2308