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Clinical Trials

Volunteer to Be Part of a Research Study

Page through all School of Medicine clinical and research trials below. There are two categories:

  • Detailed Trial Descriptions, submitted by researchers, includes trial specifics and contact information.

  • Additional Clinical Trials, which include basic study details. To contact the researcher either Google the PI (primary investigator) name or use our campus directory.

If you are a researcher seeking volunteers and your study is not posted, please
submit your Web ad here.
  

Detailed Trial Descriptions

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COMIRB Approved Advertisement TitleStudy GoalsEligibility CriteriaDate PostedCategory
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Diabetic Male and Female Volunteers Needed for Exercise Research Study
Evaluate exercise function during single leg calf exercise in people with or without type 2 diabetes
Healthy Adults 30-70 with Type 2 diabetes but not using insulin. Must be a non-smoker who exercise no more than one time per week and have a BMI of 25-40
8/26/2016 
Persons with active, moderate to severe ulcerative colitis needed
This study is being conducted to investigate the efficacy of methotrexate in treating ulcerative colitis in patients that have active, moderate to severe colitis and have failed other types of therapies.
Inclusion: Ages 18-70 Ulcerative colitis has been diagnoses by routine criteria At least one of the following applies: steroid dependent failed 5-ASA (mesalamine) therapy, such as Asacol Failed/lost response to infliximab (Remicade) Intolerant/unresponsive to azathioprine (Imuran) or 6-MP (purinethol) therapy Exclusion (partial): Existing pregnancy, lactation, or planned pregnancy (men and women)
8/26/2016 
Do you or someone you know have a food allergy to soy?
We are studying the accuracy of a food allergy blood test.  
-Are age 1 to 21 and -Do have an IgE level greater than 0.35 to wheat OR soy or -Have had a positive skin test to wheat OR soy or -Have a clinically diagnosed wheat OR soy allergy -Do NOT use >500 micrograms/day fluticasone or equivalent -Do NOT have severe asthma, daily oral steroid dosing, or asthma requiring hospitalization within a year or an ER visit in the past 6 months -Do NOT have active EoE (or recently diagnosed) -Have NOT used biologic or allergen immunotherapy within the past year
8/26/2016 
Participants Needed For Research on Military Veterans And Service Dogs
The purpose of this study is to explore the relationship between military veterans and their service dogs. Veterans will participate in one on one interviews.
Are you a military veteran? Do you have a service dog? Are you 18-89 years old? If you answered yes to the above, contact C-P.A.W.W. today.
8/26/2016 
Do you have HIV and lipodystrophy?
Our research aims to determine whether the development of Lipodystrophy Syndrome is related to changes in the types of bacteria that live in the gut (stool) that occur in HIV-infected individuals.
Non-obese HIV-positive people who are 18-70 years old. Exhibiting the symptoms described above, indicating the possibility of lipodystrophy.
8/26/2016Immune System Diseases
Type 1 Diabetes Research Study
The purpose of this research study is to evaluate the effects of an FDA-approved medication (bromocriptine QR) on insulin dosing, glucose control, and blood vessel function.
Persons 18-60 with Type 1 Diabetes, Non-smokers
8/26/2016Nutritional and Metabolic Diseases
Participants needed for a Balance and Fall-Risk Research Study for People with Multiple Sclerosis
This study involves balance and head movement testing aimed at predicting risk of falls
Are between the ages of 30 and 60 years
• have MS
• are able to turn your head at least 30 degrees to the left,
• have experienced a fall in the last 3 months
8/26/2016Nervous System Diseases
Healthy Adults Needed for Clinical Research Study
The purpose of this study is to learn about the effects (good and bad) of interferon-gamma 1b (IFN-γ 1B) has on the body's immune cells when given to healthy adults.
Ages ≥ 18 to 60 years old Has not received IFN-γ within the last 30 days of study enrollment At the time of screening, deemed healthy by the Principal Investigator with no active infections and is not currently receiving medications for an infection No diagnosis of chronic health conditions or is on long-term medications for that condition Women of childbearing potential must have a negative pregnancy test to qualify and agree to two forms of effective contraception for the duration of the study (plus one month afterward)
8/26/2016--Select a Category--
Volunteers Needed for blood donation for research and development.
To gain knowledge relating to the collection, storage and product modifications of whole blood, apheresis units, and various blood components as well as the function and biochemistry of various types of blood cells.
YOU MAY QUALIFY TO DONATE IF YOU: -Are at least 18 years old -Weigh 110 pounds or more -Are in good general health -Can attend appointment(s) during the week
8/26/2016Blood and Lymph Conditions
SPIROMICS-Subpopulations and Intermediate Outcome Measures in COPD Study
To identify subpopulations of COPD patients in order to develop newer and more effective treatments and to clearly define measureable end points so that treatment effects may be accurately assessed in a shorter period of time.
Be willing to undergo study procedures Be between the age of 40 and 80 years old Have smoked fewer than one pack of cigarettes per day for one year OR have smoked more than one pack of cigarettes per day for 20 years
8/25/2016 
Healthy Female Adolescents Needed!!!
For brain imaging research study on how the brain works with we taste sweets or receive money. Your participation could help us to develop treatments and preventive measures for anorexia nervosa and obesity
Healthy females 11 to 21 who are right-handed, free of medication with no serious medical conditions, permanent metal implants or braces/retainers, and are at a healthy body weight.
8/25/2016 
A Study to Determine the Effectiveness of Seeing Dermatologist Online Compared to In-Person
The purpose of the study is to see whether seeing a dermatologist online is just as effective as seeing one in-person. Help us determine whether online-based model is cost-saving and more efficient compared to face-to-face visits!
In order to qualify for the study, you must be 18 years or older and have psoriasis. You must have access to the internet, and a digital camera or a mobile phone with a camera.
8/25/2016 
Do You or Someone You Care for Suffer from Troublesome Drooling?
A research study is being conducted to evaluate an investigational product for Sialorrhea (troublesome drooling).
You or your loved one may be eligible to participate if you meet the following criteria: 1. Have a diagnosis of Parkinson’s disease, adult cerebral palsy, ALS, stroke, traumatic brain injury, oral cancer, or side effects of medication, or any other condition that causes Sialorrhea or troublesome drooling 2. Have never received any type of treatment using Botulinum toxin type B 3. Have ability & availability to participate in a study for up to 1 year
8/25/2016 
Parkinson's Disease Research Study
clinical research study to look at the safety and effectiveness of an investigational medication, ADS-5102 (amantadine HCl) extended release capsules, for troublesome dyskinesia in subjects with Parkinson’s disease.
You may be eligible if you have Parkinson's Disease, currently take levodopa, and are experiencing troublesome dyskinesia (involuntary twisting and turning).
8/25/2016 
Type 2 Diabetes Medication Research Study
Studying the effects of sitagliptin (a diabetes medication) on exercise capacity in people with type 2 diabetes
-Be a man or woman between 22 and 70 years old -Be generally healthy, with type 2 diabetes -Be taking metformin only for your diabetes -Be a non-smoker -Have a Body Mass Index greater than 25.0
8/25/2016Nutritional and Metabolic Diseases
Research study to investigate how therapies work to reduce tension-type headache
To understand how massage or ultrasound therapies affect blood flow within myofascial trigger points that are related to chronic pain such as tension-type headache.
Persons aged 21-49 who experience chronic or episodic tension-type headache and are not currently receiving massage, ultrasound, trigger point injection, or needling therapies.
8/25/2016Muscle, Bone, and Cartilage Diseases
" EDEN "Estrogen, Diabetes and Endothelial Function
Study the effect of estrogen on blood vessels
CONTROL PARTICIPANT ELIGIBILITY · Age 18-45 · Premenopausal · Not using hormonal birth control currently or in the last 6 months (including oral contraceptives, contraceptive patch, Depo Provera, norplant, or IUD) · Not currently pregnant or planning to become pregnant in the next 3 months · No recent history of amenorrhea (no menstrual period for at least 3 months) during the last 6 months · Non-smoker · No antioxidant therapy (vitamin C or E or multivitamin) for at least 4 weeks prior to the first study visit   Normal thyroid function (can be treated)  T1D ELIGIBILITY  · Age 18-45 · Premenopausal · Have had type 1 diabetes for at least 5 years, were treated with insulin within a year of diagnosis, and are currently treated with insulin · Not using hormonal birth control currently or in the last 6 months (including oral contraceptives, contraceptive patch, Depo Provera, norplant, or  IUD) · Not currently pregnant or planning to become pregnant in the next 3 months · No recent history of amenorrhea (no menstrual period for at least 3 months) during the last 6months · Non-smoker · No antioxidant therapy (vitamin C or E or multivitamin) for at least 4 weeks prior to the first study visit  HbA1c < 9.5  Normal kidney function (urinary albumin excretion rate < 200 µg/min)         Normal thyroid function (can be treated)
8/25/2016Heart and Blood Diseases
Rhythmic Enhancement of Motor Performance
It is known that people with Parkinson's Disease are able to move better with music or rhythm. This research study plans to learn more about the areas of the brain that react to rhythm in people with Parkinson's Disease (PD) and healthy older adults.
Healthy male older controls aged 55-85.
8/25/2016Nervous System Diseases
Volunteers needed for functional MRI research study
Patients with schizophrenia are needed for a research study to learn more about how drugs used to treat illness symptoms affect weight gain and brain responses to food. We are also studying how exercise and diet affect these responses.
Diagnosis of schizophrenia/schizoaffective disorder; taking risperidone, olanzapine, or clozapine; capable of mild/moderate exercise; BMI less than 39; no heart problems or untreated high blood pressure; capable of MRI
8/25/2016Behaviors and Mental Disorders
Attention Teens! Are You Concerned About Gaining Too Much Weight During Pregnancy?
A research study at Children’s Hospital Colorado and Colorado State University seeks pregnant teenagers age 13-19y who may be at risk for gaining too much weight during pregnancy. Consider participating in this research study focused on testing a healthy pregnant weight gain program. The study involves 1 screening visit, 6 1-hour sessions during pregnancy or usual care, and follow-up visits within 3 months of having your baby. Eligible participants could be financially compensated up to $200-$250 for their time and inconvenience.
Female 13-19 years old Pregnant
8/25/2016--Select a Category--
Physically active women and men needed for a research study on PTH and Calcium Responses to Exercise in Older Adults Experiment 2 (PACE Sr. 2)
To determine if stopping the decrease in blood calcium during exercise impacts markers of calcium loss from the bone.
 A 60-80-year-old woman or man in generally good health  Often walk for exercise and can walk for an hour at a time  Not taking osteoporosis medication  No history of Diabetes or Cardiovascular Disease
8/25/2016--Select a Category--
We are looking for Healthy Women to participate in a research study on.....Females, Aging, Metabolism, and Exercise (FAME)
To examine the role that female sex hormones play in metabolism, energy expenditure, physical activity and chronic disease.
Healthy women 40-60 who have regular menstrual cycles and using no hormonal contraceptives
8/24/2016 
Do you have Diabetes?
To find the best combination drug treatment for type 2 diabetes
Persons who have had diabetes for less than 5 years and metformin is the only diabetes medication you are taking.
8/24/2016 
Type 1 Diabetes Research Study
To study the effects of an FDA-approved medication on metabolism and blood vessel function.
Person 25-50 with type 1 diabetes who exercise vigorously less than four times per week and have normal blood pressure
8/24/2016 
CHILDHOOD and ADOLESCENT MIGRAINE PREVENTION STUDY
to test two medicines for migraine prevention in children and teens. We want to see if amitriptyline and/or topiramate are better than placebo (sugar pill) in reducing headache frequency.
Children 8-17 who have migraine headaches
8/24/2016 
Just received VARIVAX, the chickenpox vaccine?
Research study looking at the immune response to chickenpox vaccine
Age 12 months to 50 years; able to enroll in study within 10 days of vaccination.
8/24/2016 
Healthy Hispanic Female Needed
For brain imaging research study on how the brain works with we taste sweets. Your participation could help us to develop treatments and preventive measures for anorexia nervosa and obesity
Healthy females 22 to 29 who are right-handed, free of medication with no serious medical conditions, permanent metal implants or braces/retainers, and are at a healthy body weight.
8/24/2016 
Looking for HIV-positive individuals to participate in a research study on Lipodystrophy Syndrome
We are conducting a study of the relationship of bacteria in the gut to HIV infection. We are interested in finding out whether people who have metabolic diseases such as lipodystrophy (loss of fat tissue) as complications of long term antiretroviral therapy have a different makeup of their gut bacteria. We are therefore seeking volunteers with HIV infection to participate in a study of bacteria in the stool.
-Non-obese HIV positive individuals who are 18-65 years old -Either not currently on antiretroviral therapy (ART naïve or off therapy for 6 months or greater) or on effective ART with documented suppression for 6 months or greater. -We are particularly interested in enrolling subjects with lipodystrophy, but would also like to enroll individuals without lipodystrophy as controls.
8/24/2016 
Looking for HIV-positive and HIV-negative men to participate in a research study on smoking and lung disease
We are conducting a study to look at lung complications and disease in HIV/AIDS.
-Between 30 and 70 years old -Both HIV-positive and HIV-negative individuals with and without chronic obstructive pulmonary disease (COPD) -If HIV-positive, on a stable three-drug ART regimen with undetectable viral load for past 6 months
8/24/2016 
GENETIC-AF
The GENETIC-AF is a trial that will investigate the safety and effectiveness of an investigational drug on the recurrence of symptomatic atrial fibrillation in people who have heart failure. The investigational drug will be studied versus an approved drug after patients receive an electrical cardioversion.
Adults who have symptomatic atrial fibrillation may be eligible.
8/24/2016Heart and Blood Diseases

​Additional Clinical Trails

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Protocol TitlePI NameInstitution Number
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RANDOMIZED PHASE III COMPARISON OF STANDARD DOSE (60 GY) VS HIGH DOSE (74 GY) CONFORMAL RADIOTHERAPY WITH CONCURRENT AND CONSOLIDATION CARBOPLATIN/PACLITAXEL +/- CETUXIMAB IN PATIENTS WITH STAGE IIIA/IIIB NON SMALL CELL LUNG CANCER
Kavanagh, Brian D07-0851
NEW TRENDS IN HIV-RELATED RISKY PATTERNS OF INJECTING DRUG USE AND DRUGS DISTRIBUTION IN FOUR EURASIAN COUNTRIES WITH SUBSTANTIAL PRESENCE OF ATDS
Booth, Robert E08-1117
Helping Ourselves, Helping Others: The Young Womens' Breast Cancer Study
Borges, Virginia F. M.D.08-1222
S0931, "EVEREST: EVErolimus for Renal Cancer Ensuing Surgical Therapy, a Phase III Study"
Lam, Elaine Tat M.D.11-0545
GOG 9923 - A PHASE I STUDY OF INTRAVENOUS CARBOPLATIN/PACLITAXEL OR INTRAVENOUS AND INTRAPERITONEAL PACLITAXEL/CISPLATIN IN COMBINATION WITH CONTINUOUS OR INTERMITTENT / /CTEP SUPPLIED AGENT ABT-888 (NSC #737664) AND CTEP-SUPPLIED AGENT BEVACIZUMAB (NSC #704865) IN NEWLY DIAGNOSED PATIENTS WITH PREVIOUSLY UNTREATED EPITHELIAL OVARIAN, FALLOPIAN TUBE OR PRIMARY PERITONEAL CANCER
Guntupalli, Saketh Ram11-0636
A Phase II Study of the Aurora and Angiogenic Kinase Inhibitor ENMD-2076 in Previously Treated Locally Advanced and Metastatic Triple-Negative Breast Cancer
Diamond, Jennifer R M.D.11-0684
Identifying Unique Risks to Pregnancy In Perinatally Infected HIV Positive Women
Weinberg, Adriana11-1653
Oncofertility Patient Registry
Kondapalli, Laxmi A12-0389
An International Phase 3, Randomized Trial of Autologous Dendritic Cell Immunotherapy (AGS-003) Plus Standard Treatment of Advanced Renal Cell Carcinoma (ADAPT)
Lam, Elaine Tat M.D.13-1546
A phase II study of ponatinib in cohorts of patients with lung cancer preselected using different candidate predictive biomarkers.
Camidge, David Ross MD, PhD13-2002
A Phase 2B Randomized, Controlled, Multicenter, Open-Label Study of the Efficacy and Immune Response of GVAX Pancreas Vaccine (with Cyclophosphamide) and CRS-207 Compared to Chemotherapy or to CRS-207 Alone in Adults with Previously Treated Metastatic Pancreatic Adenocarcinoma
Weekes, Colin Dexter13-3144
Vascular mechanisms for the effects of loss of ovarian hormone function on cognition in women
Hildreth, Kerry L. MD14-0193
A Randomized, Double-Blind, Placebo-Controlled, Parallel-Group Study Assessing the Effect of Gelesis100 on Body Weight in Overweight and Obese Subjects with and without Type 2 Diabetes. Sponsor Protocol No. G-04. WIRB Protocol No. 20150046
Hill, James O PhD14-0383
Reclaim Deep Brain Stimulation Therapy for Obsessive-Compulsive Disorder
Abosch, Aviva M.D.14-0554
A Phase I Trial of Inhaled Iloprost for the Prevention of Lung Cancer in Former Smokers
Miller, James York E M.D.14-1247
LIBERTY 360: Prospective, Observational, Multi-Center Clinical Study to Evaluate Acute & Long Term Clinical & Economic Outfomes of Endovascular Device Intervention in Patients with Distal Outflow Peripheral Arterial Disease (PAD)
Armstrong, Ehrin14-1522
Multicenter, open-label, randomized, controlled phase III clinical study of the efficacy and safety of photodynamic therapy using porfimer sodium for injection as treatment for unresectable advanced perihilar cholangiocarcinoma Sponsor Protocol No. PIN-PHO1201 WIRB Protocol No. 20140456
Shah, Raj Jay M.D.14-1650
Functional Avoidance Radiation Therapy for Lung Cancer Patients
Vinogradskiy, Yevgeniy14-1856
Self-reported usage patterns of opioid analgesic medications after surgery
Bartels, Karsten14-1938
Pilot study of a surgery and chemotherapy-only approach in the upfront therapy of children with WNT positive standard risk medulloblastoma
Dorris, Kathleen McCarthy O'Toole14-2097
Analysis of cataract surgery outcomes performed at the Children's Hospital Colorado from January 2005 through October 2014
Singh, Jasleen14-2183
A PHASE 3B RANDOMIZED STUDY OF LENALIDOMIDE (CC-5013) PLUS RITUXIMAB MAINTENANCE THERAPY FOLLOWED BY LENALIDOMIDE SINGLE-AGENT MAINTENACE VERSUS RITYUXIMAB MAINTENANCE IN SUBJECTS WITH RELAPSED/REFRACTORY FOLLICULAR, MARGINAL ZONE OR MANTLE CELL LYMPHOMA
Bowles, Daniel W14-2282
Protocol for the Evaluation of Dario™ BGMS Performance at Elevated Altitude. Sponsor Protocol No. CP-0003; WIRB Protocol No. 20142637
Garg, Satish K14-2330
Use of Ultrasonic Bone Scalpel in Adolescent Idiopathic Scoliosis - Randomized Clinical Trial
Garg, Sumeet15-0036
A DOUBLE-BLIND, PLACEBO-CONTROLLED RANDOMIZED TRIAL TO STUDY THE VIASKIN MILK EFFICACY AND SAFETY FOR TREATING IgE-MEDIATED COW’S MILK ALLERGY IN CHILDREN (MILES STUDY) Sponsor Protocol No. MILES WIRB Protocol No. 20141789
Fleischer, David Mark M.D.15-0140
ABT-414 Alone or ABT-414 Plus Temozolomide versus Lomustine or Temozolomide for Recurrent Glioblastoma; a Randomized Phase II Study of the EORTC Brain Sponsor Protocol No. MI4-483 WIRB Protocol No. 20142384
Damek, Denise Marie15-0164
A Phase 3, Multicenter, Randomized, Double-Blind, Placebo-Controlled, Parallel-Group Study to Evaluate the Efficacy and Safety of Rivipansel (GMI-1070) in the Treatment of Vaso-Occlusive Crisis in Hospitalized Subjects with Sickle Cell Disease
Hassell, Kathryn L M.D.15-0391
Predicting the Safety and Effectiveness of Inferior Vena Cava Filters (PRESERVE) Sponsor Protocol No. G140045 P WIRB Protocol No. 20150996
Rochon, Paul J M.D.15-0537
Reproductive and Sexual Health Issues in Young Women with CF: A Patient Survey
Sagel, Scott D MD, PhD15-0575
In-Clinic Feasibility Study to Observe the Closed Loop System. Sponsor Protocol No. CEP273/Z25. WIRB Protocol No. 20130443
Slover, Robert H. M.D.15-0684


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