|Do you have Parkinson's Disease? 11-1237|
To explore the effects of different doses of endurance exercise in people with PD.
Persons 40-80 who have been diagnosed with Parkinson's Disease and are not yet taking medication or plant to start medication within the next 6 months. You must be willing to begin the exercise program immediately or after a delay of 6 months and willing to do aerobic exercise on a treadmill.
|Do you have Atopic Dermatitis (Eczema)? HS-2581|
Males and Females between 3 and 80 who have atopic dermatitis or males and females between 8 months and 80 who have a history of, or an active case of eczema hereticum (wide-spread herpes skin infection along with atopic dermatitis.
|Better Control of Type 2 Diabetes May Decrease Your Risk for Cardiovascular Disease. 10-0644|
To look at the use of an extended release formula of Exenatide compared to a placebo to maintain normal glucose levels. Ultimately to see better control of diabetes and a decrease in cardiovascular disease events.
Person 18+ with Type 2 Diabetes and take no more than 2 diabetes medications with stale doses for the last 3 months. Must not have a planned or anticipated revascularization procedure, but may have a history of cardiovascular disease and must see your primary care physician at least twice a year.
- 303-399-8020 X2059
|Type 2 Diabetes and Exercise Research Study 10-1393|
To research the effects of an investigational drug on
exercise capacity and blood vessel function.
Person 30-60 with Type 2 diabetes who exercise vigorously less than one hour per week and have normal blood pressure. Must not have smoked for at least one year and have a BMI between 25-39.9.
|Are you a Non-smoking Adult between the ages of 45 and 85? HS-1883a|
We are interested in learning more about smoking related lung disease, and need healthy non-smoking participants.
45-85 years old
Non-Hispanic White or African American
No smoking history
No evidence of lung disease
|Alterations in Lung Microbiome in Acute and Chronic HIV Infection 09-0898|
This is a prospective, observational cohort study. Three groups (A1, A2, and B) will be enrolled in parallel.
-Men and women >/= 18 years.
-Willing to follow all research requirements
-Willing to provide written informed consent
-Group A1- acute HIV infection defined as a high risk HIV exposure within the prior 30 days, or recent HIV-1 seroconversion defined as those with a high risk HIV-1 exposure
-Group A2- healthy controls: HIV-1 seronegative with no high risk HIV-1 exposure in the prior 30 days and no chronic medical illness
-Group B- HIV-1 infection diagnosed by a previous positive antibody or PCR test have been recommended to initiate HAART by their health care provider
You should not be in this study if you are a pregnant or planning to become pregnant.
|Volunteers needed to Participate in a Research Study about Rheumatoid Arthritis 01-675|
The purpose of this study is to learn more about how rheumatoid arthritis develops by studying people who do not have rheumatoid arthritis. Your participation in this study will help us determine if certain genetic and environmental factors affect the chances of developing RA-related autoantibodies in absence of rheumatoid arthritis.
You may be eligible to participate in the study if: -You are at least 40 years old -You do NOT have Rheumatoid Arthritis (RA)
|Restoring Insulin Secretion (RISE) 13-0122|
The Children’s Hospital Colorado Clinical Translational Research Center and the
National Institutes of Health are conducting a study. This study is aimed at testing
whether early treatment is beneficial to kids with early type 2 diabetes and
kids at high risk of diabetes.
10-19 years of age, Pubertal, Overweight, Fasting glucose: >90 mg/dl; Impaired glucose tolerance: >140 mg/dl; Pre-diabetes or diagnosed with diabetes for less than 6 months; Metformin
- Susan Gross
|Do You Smoke? 12-0181|
To figure out how these lung substances work in people who drink too much alcohol, who usually smoke, compared to those who do not drink heavily, but who smoke.
Smoking and nonsmoking males
|Parents or Legal Guardians of Children with Disabilities 12-1664|
Assistive Technology Partners, University of Colorado, Anschutz Medical Campus, is performing a study investigating the impact Socially Assistive Robotics has on motor, communication and cognitive skills of children with disabilities.
Children between the ages of 18 months to 5 years of age Have Significant motor and communication disabilities/delays NOT been diagnosed with blindness or deafness They are without a seizure disorder or with a well-controlled seizure disorder They have been on stable medication regime for the past 12 weeks, if they are currently taking medication.
|The Influence of Couples' Conversation on the Heart 13-2188|
The purpose of the study is to examine the influence that conversations between married couples have on the functioning of the heart.
Married Christian couples who:
• Have been married for at least 1 yr.
• Both believe in prayer.
• Are not currently taking heart medications.
• Do not have heart problems.
• Are not pregnant.
|Help Us Learn About Schizophrenia! 12-1186|
Help us learn more about a new drug that may improve thinking and concentration in people with schizophrenia.
We are looking for:
Male and female adults who smoke
18-50 years old
No previous or current mental illness
No drug use
Willing to use nicotine patch during study hospital visit
If female, willing to use birth control during the study
- 303-724-6214 or 303-724-7373
|Do you use just a rescue inhaler for asthma treatment? 29167/38|
Researchers are studying an investigational medication for the treatment of asthma in adults.
18-75 years old with asthma
Use only a rescue inhaler for asthma treatment
|Research Trial Evaluating a New Drug in Psoriasis: Now Enrolling 14-1692|
The study will evaluate an investigational drug compared to a currently approved psoriasis medication. Your participation will provide valuable information to researchers seeking new and improved therapies. You will be given either Humira, placebo, or the investigational drug for up to 28 weeks, after which you may be switched over to the active drug depending on your response.
You may be eligible to participate if 18 years of age or older and have been diagnosed with moderate to severe plaque-type psoriasis for at least 6 months.
|DO YOU LIKE TO EAT? HEALTHY MEN needed to participate in a research study 14-2411|
Research whether age affects how fat tissue responds to 1 week of overfeeding
Men who are age 25-40 yr or 55-75 yr
overweight or mildly obese
sedentary to moderately active
Van Pelt, Rachael
|Exercise for Healthy Aging 14-2207|
To determine whether a high versus a moderate intensity of cardiovascular + strength training has a greater improvement on health and quality of life.
Eligibility: Men aged 50-68, no major health problems that would interfere with the ability to exercise; if diabetic, must be well-controlled on oral medications (no insulin); body mass index between 20 and 40; no current/chronic infections.
Erlandson, MD, Kristine
|Persons Age 50 and Older Needed for Research Study 15-0923|
This study will look at how the immune system responds to receiving the shingles vaccine and the flu vaccine at the same time
50+ years of age; in general good health; no prior history of shingles; never received the shingles vaccine.
|Vaccine Research Study Persons 60 and Older 15-1432|
The University of Colorado Denver School of Medicine is conducting a research study to learn more about an investigational vaccine to prevent Respiratory Syncytial Virus (RSV) in older adults. The goal of this study is to see if the vaccine prevents respiratory illness caused by RSV, to learn about side effects it might cause, and to see if it can be given at the same time as the flu vaccine. Eligible participants will receive a currently licensed flu vaccine and the investigational RSV vaccine. Enrollment is time sensitive with enrollment visit is taking place from mid-September thru November 30th.
• Are age 60 or older,
• Are in generally good health, and
• Have not received a flu vaccine in the last 6 months
|Trouble Sleeping? HS-2655|
Study the effects of two different study drugs, one or two non-drug interventions and/or a combination of both to treat insomnia.
Persons 21+ who have trouble falling or staying asleep at night.
|Give Us a Hand 12-1084|
To better understand Multiple Sclerosis in children and teens.
Between the ages of 3-20 AND have Multiple Sclerosis diagnosed before 18
Do not have MS
|Are you an African American with asthma? HS-2805|
We are studying why some African American people have trouble with their asthma despite taking asthma medications.
Children age 5-17 and non-smoking Adults age18 and older who have asthma symptoms despite asthma treatment • African American ancestry (have at least one African American grandparent)
Wechsler, MD, Michael
|Peanut and Tree-Nut Allergy Research Study 13-2102|
The purpose of this study is to determine how the body's immune system interacts with nuts and other foods to cause allergic reaction.
6-75 years of age. Have a diagnosis of peanut and/or tree-nut allergy made by either skin test or blood tests. Have no known peanut and/or tree-nut allergy.
|Research about the Effect of Carbamazepine medication on the Etonogestrel Contraceptive Implant (Implanon®/Nexplanon®) 14-0584|
Do you currently have a birth control implant (Implanon®/ Nexplanon®) and are interested in participating in a research study to better understand the effects of certain medication on the implant?
• Women ages 18-45 who have had a birth control implant 1 to 3 years • Do not take any medications that are known to effect liver enzymes • Be willing to abstain during the study period or use a secondary form of non-hormonal contraception • Have baseline systolic blood pressure
|Do you have human growth hormone (hGH) deficiency? 13-2629|
Primary: To demonstrate a clinical superiority of MOD-4023 over placebo in terms
of decrease in Fat Mass (FM) in adult subjects with Growth Hormone Deficiency
a. To determine the efficacy of MOD-4023 over placebo in other body
composition variables (such as lean body mass and waist-to-hip ratio)
b. To evaluate the safety and tolerability of MOD-4023 over placebo in adult
subjects with GHD
c. To determine the IGF-I and IGFBP-3 serum levels
Adult men and women aged 23 to 70 years of age diagnosed with either adult or childhood onset growth hormone deficiency (GHD).
|Are you a parent of a child with a developmental disability and willing to contribute to a research project to increase awareness and understanding? 14-1287|
The purpose of this study is to gain knowledge on the topic of everyday stressors that affect the lives of children with developmental disabilities, as well as their parents/caregivers
Are you a parent of a child with a developmental disability and willing to contribute to a research project to increase awareness and understanding?
- (303) 520-7346
|Healthy Female Adults Needed!!! 07-0816|
For brain imaging research study on how the brain works with we taste sweets. Your participation could help us to develop treatments and preventive measures for anorexia nervosa and obesity
Healthy females 22 to 29 who are right-handed, free of medication with no serious medical conditions, permanent metal implants or braces/retainers, and are at a healthy body weight.
|Do you have an egg allergy? HS-2764|
To see if taking Baked Egg Therapy vs. Oral Immunotherapy may help egg-allergic children tolerate eggs.
males and females 3 to 16 years old, with documented egg allergy, ability to make regular visits to National Jewish Health for up to 2 years.
|Randomized Trial to Prevent Vascular Events in HIV (REPRIEVE) 15-0023|
Pitavastatin is a statin that along with diet is used for the treatment of high cholesterol. It also lowers triglyceride levels in the blood. The main purpose of this clinical trial is to see if pitavastatin can prevent heart disease and heart disease related deaths in people with HIV infection who are taking HIV medications.
This study lasts about 6 years (21 visits) and you may be eligible if:
• You have HIV and are between the ages of 40 and 75.
• You have been on antiretroviral therapy (ART) for at least 6 months.
• You have a CD4+ cell count > 100.
• You have no history of cardiovascular disease
(history of heart attack or stroke, etc.).
• You are not currently using a statin drug.
Campbell, MD, Thomas
|We are looking for Healthy Men and Women to participate in a research study to determine how Exercise Impacts Fat Metabolism During Sleep 13-0359|
The University of Colorado Anschutz Medical Campus is recruiting healthy men and women to participate in a research study investigating how exercise performed during the day impacts hormones and metabolism during sleep. Adults spend about one-third of their lives sleeping yet little is known about metabolism during this period or how day time exercise influences sleeping metabolism. Learning more about sleeping metabolism will improve our understanding of how the body regulates body weight.
This research study is looking for healthy men and women aged 20 to 35 years, who have a BMI < 30, exercise less than 3 days per week, and have a regular sleep schedule.
|Are you Interested in Being in a Weight Loss Research Study? 13-1550|
Volunteers needed for a research study to determine the best time to begin exercise within a lifestyle weight loss program.
• Be a man or woman between 18 and 55 years old
• Be generally healthy without diabetes or heart disease
• Be a non-smoker
• Not currently exercising regularly
• Have a BMI between 28 and 40 kg/m2
In order to enroll all participants must meet specific criteria. The criteria listed above is only a partial list of all the requirements to participate in this research study. Only a clinical research staff member can determine eligibility.