|Healthy Females needed! Ages 11 to 29 07-0816|
For brain imaging research study on how the brain works with we taste sweets or receive money. Your participation could help us to develop treatments and preventive measures for anorexia nervosa and obesity
Healthy females 11 to 29 who are right-handed, free of medication with no serious medical condition or permanent metal implants or braces/retainers.
|We are looking for Healthy Women to participate in a research study on.....Females, Aging, Metabolism, and Exercise (FAME) 12-1157|
To examine the role that female sex hormones play in metabolism, energy expenditure, physical activity and chronic disease.
Healthy women 40-60 who have regular menstrual cycles and using no hormonal contraceptives
|Do you have Diabetes? 13-0131|
To find the best combination drug treatment for type 2 diabetes
Persons who have had diabetes for less than 5 years and metformin is the only diabetes medication you are taking.
|Type 1 Diabetes Research Study 11-0693|
To study the effects of an FDA-approved medication on metabolism and blood vessel function.
Person 25-50 with type 1 diabetes who exercise vigorously less than four times per week and have normal blood pressure
|CHILDHOOD and ADOLESCENT MIGRAINE PREVENTION STUDY 12-0776|
to test two medicines for migraine prevention in children and teens. We want to see if amitriptyline and/or topiramate are better than placebo (sugar pill) in reducing headache frequency.
Children 8-17 who have migraine headaches
|Volunteers are invited for a research studying looking at pain in knee osteoarthritis 12-1188|
To better understand the complex experience of pain for people with knee osteoarthritis
Persons 50 or older who have been diagnosed with knee osteoarthritis
|Just received VARIVAX, the chickenpox vaccine? 13-2122|
Research study looking at the immune response to chickenpox vaccine
Age 12 months to 50 years; able to enroll in study within 10 days of vaccination.
|Healthy Women Needed for Cardiovascular Research Study 06-0537|
The purpose of this study is to investigate how the menopause transition and the loss of estrogen impacts the health and function of arteries in women.
- Premenopausal women 18-49 years, Perimenopausal women 40-55 years and Postmenopausal women 45-70 years
- Volunteers should NOT be taking Birth Control or Hormone Replacement Therapy (HRT) or exercising vigorously more than 2 days per week.
|Research investigating the influence of a Monopoly Game on Subtle Behaviors 14-0719|
This research study plans to learn more about how a stressful game of monopoly will influence subtle behaviors.
To qualify for the study you must be:
Between the ages 19-25
Consider yourself Hispanic/Latino
Born in the United States
Be a non-smoker
Have played the game Monopoly before
Cardel, PhD, RD, Michelle
|Looking for HIV-positive individuals to participate in a research study on Lipodystrophy Syndrome 14-1595|
We are conducting a study of the relationship of bacteria in the gut to HIV
infection. We are interested in finding out whether people who have
metabolic diseases such as lipodystrophy (loss of fat tissue) as complications of
long term antiretroviral therapy have a different makeup of their gut bacteria.
We are therefore seeking volunteers with HIV infection to participate in a study
of bacteria in the stool.
-Non-obese HIV positive individuals who are 18-65 years old
-Either not currently on antiretroviral therapy (ART naïve or off therapy for 6
months or greater) or on effective ART with documented suppression for 6
months or greater.
-We are particularly interested in enrolling subjects with lipodystrophy, but
would also like to enroll individuals without lipodystrophy as controls.
Lozupone, PhD, Catherine
|Looking for HIV-positive and HIV-negative individuals to participate in a research study on smoking and lung disease 13-2986|
We are conducting a study to look at lung complications and disease in
-Between 30 and 70 years old
-Both HIV-positive and HIV-negative individuals with and without chronic
obstructive pulmonary disease (COPD)
-If HIV-positive, on a stable three-drug ART regimen with undetectable viral
load for past 6 months
Campbell, MD, Thomas
|A Two-Part Multicenter Prospective Longitudinal Study of CFTR-Dependent Disease Profiling in Cystic Fibrosis (PROSPECT) 14-2010|
The purpose of this research study is to answer questions about Cystic Fibrosis (CF).
CF is a disease that affects the body’s ability to move salt and fluids in and out of the
cells of the lungs, intestines, pancreas, and sweat glands. CF is caused by changes
(mutations) in a gene that produces a protein called the cystic fibrosis
transmembrane conductance regulator (CFTR). Some of these mutations cause
CFTR to lose all function while other mutations cause CFTR to lose some function.
The PROSPECT Study has two parts. In part A of this study, we are trying to answer
the questions below:
How is CFTR function different between people with CF and those without
Can you tell something about a person’s level of CFTR function by measuring
proteins and other indicators (‘biomarkers’) in blood, sputum, and/or stool?
How much do biomarker levels change when tested at two different times
over two weeks?
Part A CORE Study Non-CF Controls
1. Written informed consent (and assent when applicable) obtained from
subject or subject’s legal representative.
2. Be willing and able to adhere to the study visit schedule and other protocol
3. Male or female greater or equal to 12 years of age at Visit 1.
4. Have a body mass index (BMI) of:
For subjects greater or equal to 18 years of age: less than or equal to 30 kg/m2
For subjects 12 – 17 years of ≤ 95th percentile
5. Be a non-smoker ≥ 1 year prior to Visit 1 and have ≤10 pack-year history of
Part A CORE Study Non-CF Controls
1. Presence of a condition or abnormality that, in the opinion of the
Investigator, would compromise the safety of the patient or the quality of the
2. Have at least one known CFTR mutation.
3. First degree relative of a patient known to have CF, unless previous genetic
analysis (testing must have included BOTH mutations of the related CF
patient) indicates noncarrier status.
4. A history of any clinically significant medical illness or medical disorder
that requires ongoing medical therapy, including (but not limited to)
cardiovascular disease, neuromuscular disease, hematological disease
including bleeding disorders, chronic respiratory disease (including persistent
asthma), hepatic or gastrointestinal (GI) disease, neurological disease,
neoplastic disease, renal diseases, or endocrine disorders including diabetes.
5. Acute illness requiring any new prescription or over-the-counter treatment
within 14 days prior to Visit 1.
6. Major or traumatic surgery within 12 weeks prior to Visit 1.
7. Loose watery stools more than three times a day lasting more than 24 hours
within the two weeks prior to Visit 2.
8. For women of child-bearing potential: a positive pregnancy test at Visit 1.
9. Initiation of any new chronic therapy within 28 days prior to Visit 1.
10. Use of an investigational agent within 28 days prior to Visit 1.
|Cognitive Dysfunction in Parkinson's Disease 10-0771|
This research study plans to use simultaneous brain scans and memory tasks to see if stimulating certain areas of the brain improves thinking and memory. This is not a treatment study
Healthy males over 50 with Parkinson's disease on stable doses of medication and have no metal in the body (dental work may be ok).
|EFFECTS OF TESTOSTERONE THERAPY IN YOUNG ADOLESCENTS WITH KLINEFELTER SNDROME (47.XXY) 11-0874|
This study will study the effects of testosterone therapy on behavior, mood, problem solving, attention span, and motor skills in adolescent males with Klinefelter syndrome in early puberty. During this period in early puberty there is a lot of variability in how and when doctors start testosterone therapy. This study will evaluate if there are benefits to starting testosterone therapy in early puberty.
Participants with Klinefelter syndrome in early puberty (around age 10-15).
|Are you interested in a supervised weight loss intervention? 12-1352 |
Volunteers needed for a research weight loss study to examine the neuronal and behavioral changes that occur with different
weight loss interventions.
- 21-65 years old
- Non- smoker
- Non- Diabetic
- Exercise no more than 1 time a week
- Maintained your current weight for the last 6 months
- Have a body mass index of 30 -40
(check it out at http://nhlbisupport.com/bmi/
|Are you a Parkinson's patient not requiring symptomatic treatment with drugs? 13-2808|
This research study explores the effects of an FDA approved drug on Parkinson's disease.
Recently diagnosed Parkinson's patients who are not taking any drugs for symptomatic relief or are willing to go off drugs for the duration of the study with neurologist approval. We are also looking for healthy control participants.
|The Health Influences in Puberty "HIP" study 07-0988|
Research study about puberty and risk for type 2 diabetes
Healthy boy between 11 and 13 years of age
Healthy girl between 9 and 11 years of age
|Volunteers with Alzheimer’s Disease Needed for Memory Study 12-1273|
To examine the safety and efficacy of the study drug, Sargramostim (Leukine®), on memory in adults with Mild-to-Moderate Alzheimer’s Disease.
1. Age 55 to 85 years;
2. Should have a mild-to-moderate Alzheimer's Disease diagnosis (Mini-Mental State Examination 10-26 inclusive);
3. If on anti-dementia treatment should be on stable treatment for at least 2 months (i.e. cholinesterase inhibitor and/or Memantine or Axona);
4. Stable on all other medications for at least 30 days prior to screen;
5. Should be fluent in English;
6. Should be physically able to participate by medical history, clinical exam and tests;
7. Should have a study partner to accompany them to scheduled visits.
|Healthy Hispanic Female Adults Needed 07-0816|
For brain imaging research study on how the brain works with we taste sweets. Your participation could help us to develop treatments and preventive measures for anorexia nervosa and obesity
Healthy females 22 to 29 who are right-handed, free of medication with no serious medical conditions, permanent metal implants or braces/retainers, and are at a healthy body weight.
|Do you have high blood pressure? 13-3174|
Researchers at the University of Colorado Hospital are conducting a research study to help predict if blood pressure medications will work for you.
Subject must be between 30 and 75 years of age and have a diagnosis of uncontrolled hypertension (high blood pressure). As part of the study, you may be eligible for free medication and free clinic visits to check your blood pressure
|T•A•C•I•T - Therapy After Cochlear Implants Using Telemedicine 12-1103|
This research plans to learn more about the use of telemedicine as a means of providing therapy to children who have a cochlear implant(s). While Auditory-Verbal Therapy has typically been delivered in person, many people are starting to access therapy over the internet. We are conducting this research to determine if the outcomes of therapy are the same when AVT is delivered in person and via telemedicine.
The T•A•C•I•T team is looking for children ages 6 mos.-6 yrs. old who were implanted with cochlear implant(s) before age 3 ½.. Each child will spend nine months in both the in-person and telemedicine condition. The therapist will remain the same throughout the study. Total participation will last 18 months. The child will be tested three times: once when the study starts, and every nine months after that. A qualified study team member will administer speech, listening, and language tests to the child. They will also receive tests to identify how well their auditory area of the brain is developing.
|Participants with Chronic Kidney Disease Needed for a Research Study about Phosphate 13-0328|
We are looking for men and women to participate in a research study examining whether
lowering blood levels of phosphate will improve blood vessel function.
We need men and women who:
-are age 40-79 years old; women must be post-menopausal;
-have chronic kidney disease stage 3b or 4 (estimated GFR 15-45 ml/min);
-are not taking phosphate binders;
-do not have high blood phosphate (>5.5 mg/dL).
|Are you interested in a research study of a new investigational birth control patch? 14-1868|
We are recruiting women to join a large clinical research study of a contraceptive patch.
The patch contains the same type of hormones that are in many birth control pills.
The patch is designed to be flexible and is applied onto the skin, just once a week.
• Be sexually active at least once a month
• Need to use birth control
• Not wish to become pregnant for at least 1 year
• Be able to use the patch as your only form of birth control for at least 1 year.
|ESS-NSPAS Study 14-1808|
Bayer HealthCare is sponsoring a medical research study to look at the effectiveness of Essure after having a procedure (NovaSure) that decreases your heavy menstrual bleeding. Both Essure and NovaSure are approved by the FDA.
This study is enrolling patients now and you may qualify to participate.
Are you currently using the Essure method of contraception?
Are your periods heavy, frequent or prolonged?
One important prerequisite is - you must have had a successful Essure placement AND be willing to undergo a NovaSure endometrial ablation, a treatment option for heavy menstrual bleeding (menorrhagia).
|Do you suffer from scalp psoriasis? 14-1577|
We are researching a new drug that may help with your scalp psoriasis.
We invite you to participate in a research study testing a novel therapy in scalp psoriasis.
To qualify for this study, you must be an adult 18 years of age or older, and you must be diagnosed with moderate to severe scalp psoriasis (for at least six months).
|Would you like to volunteer for a research study? 14-1561|
Your participation in this study will help the researcher to understand more about cervical cancer prevention among Hispanic women who have Mexican and Mexican-American cultural values.
English speaking female, who was born, and currently lives, in the U.S., has had a pap smear, is between the ages 21-50 years old, and self-identifies as Mexican or Mexican-American.
- (720) 445-5623
|Volunteers with Chronic Kidney Disease needed for a Uric Acid Lowering Research Study 10-0625|
To understand the effect of lowering serum uric acid levels on vascular function in individuals with CKD by comparing Allopurinol therapy and a placebo.
Persons 18+ with moderate chronic kidney disease (CKD stage III) with estimated glomerular filtration rates between 30-60 mL/min/1.73m2
|Research Study: "Anxiety Risk in Teens" 12-0424|
To learn more about risk factors for anxiety in adolescents with cyclic vomiting syndrome.
Adolescents 13-18 who have been diagnosed with either an anxiety disorder or cyclic vomiting syndrome
|Are you interested in learning about how your breast milk helps your baby grow? 12-0629|
To find out how maternal size and diabetes status affect her breast milk
To find out what unique parts of breast milk may affect how infants grow.
To learn how to ensure infants receive the best nutrition possible
Women 20-35 who are at least 28 weeks into their pregnancy and planning on exclusively breastfeeding their infant for at least 4 months and delivering at University of Colorado Hospital.
|Free Family Therapy for Youth with Mood Problems 11-1048|
Helping youth and their families understand and cope with mood swings, develop plans for preventing moods from getting worse, communicate more effectively and solve family problems
- Youth between 9-17 who has recently had significant mood swings, has at least one parent with bipolar disorder and does not abuse alcohol or substances.
- Must agree not to participate in family therapy with another provider for the first year.