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Clinical Trials

Volunteer to Be Part of a Research Study


You can search for specific diseases or conditions in our Clinical Trials list (the page takes a few seconds to load due to the quantity of trials).

Page through all School of Medicine clinical and research trials below, or click here to look for specific types of trials.
(It will take a few seconds to load) There are two categories: 

  • Detailed Trial Descriptions, submitted by researchers, includes trial specifics and contact information.

  • Additional Clinical Trials, which include basic study details. To contact the researcher either Google the PI (primary investigator) name or use our campus directory.

If you are a researcher seeking volunteers and your study is not posted, please submit your Web ad here.  

Detailed Trial Descriptions

 Results From Research and Clinical Trials : Selected site
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COMIRB Approved Advertisement TitleStudy GoalsEligibility CriteriaDate Posted
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Do you have Parkinson's Disease?
To explore the effects of different doses of endurance exercise in people with PD.​
Persons 40-80 who have been diagnosed with Parkinson's Disease and are not yet taking medication or plant to start medication within the next 6 months. You must be willing to begin the exercise program immediately or after a delay of 6 months and willing to do aerobic exercise on a treadmill.
4/18/2014
Do you have Atopic Dermatitis (Eczema)?
To study eczema
Males and Females between 3 and 80 who have atopic dermatitis or males and females between 8 months and 80 who have a history of, or an active case of eczema hereticum (wide-spread herpes skin infection along with atopic dermatitis.
4/18/2014
Better Control of Type 2 Diabetes May Decrease Your Risk for Cardiovascular Disease.
To look at the use of an extended release formula of Exenatide compared to a placebo to maintain normal glucose levels. Ultimately to see better control of diabetes and a decrease in cardiovascular disease events.​
Person 18+ with Type 2 Diabetes and take no more than 2 diabetes medications with stale doses for the last 3 months. Must not have a planned or anticipated revascularization procedure, but may have a history of cardiovascular disease and must see your primary care physician at least twice a year.
4/18/2014
Are you a Non-smoking Adult between the ages of 45 and 85?
We are interested in learning more about smoking related lung disease, and need healthy non-smoking participants.
45-85 years old Non-Hispanic White or African American No smoking history No evidence of lung disease
4/18/2014
Influenza Study
Doctors at the National Institutes of Health are conducting a research study (IRC-004) to investigate whether treating the flu decreases the amount of virus we can detect in your nose, and to understand whether the change in the amount of virus is associated with changes in your symptoms.
Volunteers may be male or female and must: -be at least 18 years old -have a history of an influenza-like illness -have an onset of illness within the past 48 hours -test positive for influenza
4/18/2014
Alterations in Lung Microbiome in Acute and Chronic HIV Infection
This is a prospective, observational cohort study. Three groups (A1, A2, and B) will be enrolled in parallel.
-Men and women >/= 18 years. -Willing to follow all research requirements -Willing to provide written informed consent -Group A1- acute HIV infection defined as a high risk HIV exposure within the prior 30 days, or recent HIV-1 seroconversion defined as those with a high risk HIV-1 exposure -Group A2- healthy controls: HIV-1 seronegative with no high risk HIV-1 exposure in the prior 30 days and no chronic medical illness -Group B- HIV-1 infection diagnosed by a previous positive antibody or PCR test have been recommended to initiate HAART by their health care provider You should not be in this study if you are a pregnant or planning to become pregnant.
4/18/2014
Has your child been diagnosed with generalized anxiety disorder?
to study sleep and brain activity
• between the ages of 12 & 18 • diagnosed with GAD OR • not diagnosed with any psychological disorders AND who are • right-handed • without orthodontic braces • not taking sleep medications
4/18/2014
Volunteers needed to Participate in a Research Study about Rheumatoid Arthritis
The purpose of this study is to learn more about how rheumatoid arthritis develops by studying people who do not have rheumatoid arthritis. Your participation in this study will help us determine if certain genetic and environmental factors affect the chances of developing RA-related autoantibodies in absence of rheumatoid arthritis.
You may be eligible to participate in the study if: -You are at least 18 years old -You do NOT have Rheumatoid Arthritis (RA)
4/18/2014
Restoring Insulin Secretion (RISE)
The Children’s Hospital Colorado Clinical Translational Research Center and the National Institutes of Health are conducting a study. This study is aimed at testing whether early treatment is beneficial to kids with early type 2 diabetes and kids at high risk of diabetes.
10-19 years of age, Pubertal, Overweight, Fasting glucose: >90 mg/dl; Impaired glucose tolerance: >140 mg/dl; Pre-diabetes or diagnosed with diabetes for less than 6 months; Metformin
4/18/2014
Participate in a Research Study at the University of Colorado. UC Denver is Conducting a Study on Back Pain and Spinal Manipulation at the Anschutz Medical Campus
To study muscle activity during chiropractic spinal manipulations
1) 18-55 years of age 2) Male 3) Must have low back pain
4/18/2014
Have you experienced a preterm birth?
If you participate, the information we learn from you will help us better understand how and why 1 out of 10 pregnancies in the US end in preterm birth.
1. Women ages 18-45 years old 2. willing to meet for 1-2 hours in a focus group setting 3. a mother of a baby who was born more than 3 weeks before your due date (
4/18/2014
Do You Smoke?
To figure out how these lung substances work in people who drink too much alcohol, who usually smoke, compared to those who do not drink heavily, but who smoke.
Smoking and nonsmoking males
4/18/2014
Participants with Chronic Kidney Disease and Vitamin D Deficiency Needed for a Research Study
This study will examine whether nutritional or active vitamin D supplementation will improve blood vessel function​.
Person 18-80 with chronic kidney disease stage 3B or 4 (estimated GFR 44-15 m;/min) with a vitamin D deficiency or insufficiency.  Women must not be pregnant or breastfeeding.
4/17/2014
Asthmatics Needed
Test pulmonary function.
Person 18+ who have been diagnosed with asthma , do not smoke and are currently on inhaled steroid or other daily controller medications.
4/17/2014
Trouble Sleeping?
Study the effects of two different study drugs, one or two non-drug interventions and/or a combination of both to treat insomnia.
Persons 21+ who have trouble falling or staying asleep at night.
4/17/2014
MS Volunteers Needed for Research Study
Looking to see if there is a cognitive improvement with the treatment of oral estriol as compared to oral placebo.
We are looking for: • Women 18-50 years old • Diagnosed with definite relapsing-remitting, secondary-progressive multiple sclerosis or primary-progressive multiple sclerosis • MS disease duration of 15 years or less • On stable dose of standard MS treatment with Copaxone®, Betaseron® (or Extavia®), Rebif®,Avonex®, Gilenya®, Aubagio®, Tecfidera®, or no treatment ----You are not eligible for the study if you are pregnant, breast-feeding, smoke, or have other serious medical conditions.
4/17/2014
Give Us a Hand
To better understand Multiple Sclerosis in children and teens.
Between the ages of 3-20 AND have Multiple Sclerosis diagnosed before 18 OR Do not have MS
4/17/2014
Healthy subjects needed for high altitude research study
For a research study on the effects of drugs on blood oxygen levels
Healthy Male subjects needed that are: - Between the ages of 18-45 years old - Do not smoke - Engage in regular physical exercise - Willing and able to engage in moderate physical activities in a simulated high altitude environment
4/17/2014
Are you an African American with asthma?
 We are studying why some African American people have trouble with their asthma despite taking asthma medications.
 Children age 5-17 and non-smoking Adults age18 and older who have asthma symptoms despite asthma treatment • African American ancestry (have at least one    African American grandparent)
4/17/2014
Seeking healthy persons for testing an investigational drug for mental illness
Single administration under medical supervision. Compensation provided.
Healthy male and female adults, 18-50 years old with no previous or current mental illness. No drug use. Nonsmokers. If female, willing to use birth control.
4/17/2014
If you child suffers from rashes or skin allergies he or she may qualify to take part in a research study.
To test seven new antigens on the child and adolescent population to add to the current standard test
Children and adolescents 6-17 diagnosed with contact dermatitis or may have contact dermatitis who are willing to wear test patches for 2 days and are available for follow-up visits
4/16/2014
Investigations in Gestational Origins of Lifetime Development: Understanding health begins before birth. Are you in your first trimester of Pregnancy?
To learn more about how your metabolism is connected to your baby's growth and development
Healthy Women ages 18-35 who are 10-14 weeks pregnant with single baby.  Norm BMI or 30-38 who are willing to complete 5 visits during pregnancy and agreeable to an infant blood draw at birth and DXA postpartum.  Delivery must be at University of Colorado Hospital.  there is an option to take part in a 1 year follow-up which entails an additional 4 visits and another DXA at 1 year of life.
4/16/2014
We are Currently Enrolling People with Down syndrome for a study in Dr. Pelak's Brain and Vision Research lab at the University of Colorado Anschutz Medical Campus.
To examine visual brain function in people with mild memory impairments to detect early signs of Alzheimer's Disease.​
Persons 19-30 who have Down Syndrome
4/16/2014
You are invited to participate in EMERALD, as research study about Metformin and Type 1 Diabetes in Adolescents
​To determine the effects of Metformin on Cardiovascular Function in Adolescents with Type 1 Diabetes.
Persons 12-21 who have Type 1 Diabetes, non-smoker and exercise no more than 3 hours a week.  You must be willing to take metformin or placebo (sugar pill) for 3 months.   Other exclusions apply, please contract study for more information
4/16/2014
Children's Hospital, department of Pediatric Neurology is conducting a research study
evaluating the effects of a single treatment of injected BOTOX® (Botulinum Toxin Type A) for chronic migraine(s) in adolescents.
Adolescents 12-17 who have no serious medical conditions but have at least 15 headaches a month for the last 6 months. You not have any previous BOTX treatments or are not currently using any prophylactic medicine.
4/16/2014
Non-Alcoholic Fatty Liver Disease and Obstructive Sleep Apnea: Mechanistic Links between Hypoxemia and Liver Injury
To learn if obstructive sleep apnea and low oxygen levels have a role in developing Non-Alcoholic Fatty Liver Disease (NAFLD).​​​
Children 10-17 who have a normal weight and no serious medical problems
4/16/2014
Are you using Implanon or Nexplanon for birth control?
study on a potential treatment for bothersome bleeding/spotting related to the etonogestrel implant.
Women 18-44 who are experiencing bothersome bleeding/spotting while using Implanon or Nexplanon
4/16/2014
Exercise and Cancer Prevention Research Study
The goal of this study is to better understand the biological mechanisms associated with exercise and reduced risk for breast cancer.
You must be a female between the ages of 30-45 to participate in this study. You must be planning to live in the Denver metropolitan area for the next 10 consecutive months. You should not be a regular exerciser because this study is for people who do not exercise right now; however, you should be willing to participate in an exercise program 4 times per week for 16-weeks.
4/16/2014
Blood Donor Volunteers Needed for Research Study
We are trying to learn more about blood loss to provide better treatment for trauma patients. This study plans to learn if non-invasive monitoring can accurately track blood loss and changes in stroke volume.
1. Be approved by CHCO Blood Donation Center for donating blood 2. Be 18-89 years old 3. Have previously donated blood or plasma (at any blood donation center)
4/16/2014
Frequent Cold Sores?
This study will look at the body's immune response (how the body fights infection) to the onset of cold sores.  1-2 study visits for blood draws over the course of 3 months.
18+ years of age; have prior history of cold sores; have developed a cold sore within the last 10 days.
4/16/2014

​Additional Clinical Trails

 Results From Research : Selected site
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Engineering Clinical Evaluation of Philips Medical's Modified CX50 with Revision MI 3 Software and Q-Station Software with new Release 9.0.Sponsor Protocol Philips Medical. WIRB Protocol No. 20110948
Salcedo, Ernesto11-0797
Adult Congenital Heart Disease Quality Enhancement Research Initiative (ACHD QuERI). Sponsor Protocol CHRC2011-ACHD001. WIRB Protocol No. 20111582
Kay, Joseph12-1161
The Targeting Acute Congestion with Tolvaptan in Congesting Heart Failure Study (Tactics-HF). WIRB Protocol No. 20121793
Shakar, Simon13-0112
ASPIRE Early Ablation Therapy for the Treatment of Ischemic Ventricular Tachycardia in Patients with Implantable Cardioverter Defibrillators. WIRB Protocol No.20121193
Tzou, Wendy13-0280
A PHASE 3, MULTICENTER, RANDOMIZED, OPEN-LABEL STUDY TO COMPARE THE EFFICACY AND SAFETY OF POMALIDOMIDE, BORTEZOMIB AND LOW-DOSE DEXAMETHASONE VERSUS BORTEZOMIB AND LOW-DOSE DEXAMETHASONE IN SUBJECTS WITH RELAPSED OR REFRACTORY MULTIPLE MYELOMA. Sponsor Protocol # CC-4047-MM-007. WIRB Protocol # 20121754
Smith, Clayton13-2056
Exhibit B-14 Specific Research Plan for Voyager 1.0. WIRB Protocol # 20131141
Salcedo, Ernesto13-2062
A Single-arm Study to Assess the Efficacy and Safety of Oral Rigosertib in Transfusion-dependent, Low or Intermediate-1, Myelodysplastic Syndrome Patients Based on the International Prognostic Scoring System. Sponsor Protocol # 09-07. WIRB Protocol # 20131128
Pollyea, Daniel13-2064
COMBI-AD: A phase III randomized double blind study of dabrafenib (GSK2118436) in COMBInation with trametinib (GSK1120212) versus two placebos in the ADjuvant treatment of high-risk BRAF V600 mutation-positive melanoma after surgical resection. Sponsor Protocol # BRF115532. WIRB Protocol # 20130566
Gonzalez, Rene13-2093
A PROSPECTIVE, RANDOMIZED, CONTROLLED, PARALLEL GROUPS, MULTICENTER POST-APPROVAL STUDY OF THE GLAUKOS® ISTENT® TRABECULAR MICRO-BYPASS STENT SYSTEM IN CONJUNCTION WITH CATARACT SURGERY. SPONSOR PROTOCOL # GTS100-PAS2. WIRB PROTOCOL # 20130739
Seibold, Leonard13-2098
A randomized, double blind, placebo-controlled, multicenter phase III study of regorafenib in patients with hepatocellular carcinoma (HCC) after sorafenib. Sponsor Protocol No. BAY 73-4506 / 15982. WIRB Protocol No. 20121899
Purcell, William13-2135
A Phase I Dose Escalation Open-Label Safety, Pharmacokinetic and Pharmacodynamic Study to Determine the Recommended Phase II Dose of GSK1120212 Dosed in Combination with GSK2141795. Sponsor Protocol No. TAC113886. WIRB Protocol No. 20130890
Gonzalez, Rene13-2146
A Double-Blind, Placebo-Controlled Evaluation of the Safety and Efficacy of Vilazodone in Adolescent Patients with Major Depressive Disorder. Sponsor Protocol No. VLZ-MD-21. WIRB Protocol No. 20130945
Wamboldt, Marianne13-2149
A Phase 2, Randomized, Multicenter Study of PEGPH20 (PEGylated Recombinant Human Hyaluronidase) Combined with nab-Paclitaxel Plus Gemcitabine Compared With nab-Paclitaxel Plus Gemcitabine in Subjects With Stage IV Previously Untreated Pancreatic Cancer. Sponsor Protocol No. HALO-109-202. WIRB Protocol No. 20130824
Weekes, Colin13-2161
A PHASE IB OPEN-LABEL STUDY OF THE SAFETY AND PHARMACOKINETICS OF MEHD7945A IN COMBINATION WITH EITHER CISPLATIN AND 5-FU OR PACLITAXEL AND CARBOPLATIN IN PATIENTS WITH RECURRENT/METASTATIC SQUAMOUS CELL CARCINOMA OF THE HEAD AND NECK. Sponsor Protocol No. GO28909. WIRB Protocol No. 20131256
Jimeno, Antonio13-2170
A PHASE II, MULTICENTER, SINGLE-ARM STUDY OF MPDL3280A IN PATIENTS WITH PD-L1-POSITIVE LOCALLY ADVANCED OR METASTATIC NON-SMALL CELL LUNG CANCER. Sponsor Protocol No. GO28625. WIRB Protocol No. 20130654
Camidge, David13-2173
A Multi-Center, Dose Finding, Open Label, Phase 1 Study of RX-5902 in Subjects with Advanced or Metastatic Solid Tumors. Sponsor Protocol No. RX-5902-P1-01. WIRB Protocol No. 20131320
Eckhardt, Sue13-2176
A Phase 3, Randomized, Double-Blind Study of Nivolumab Monotherapy or Nivolumab Combined with ipilimumab Versus Ipilimumab Monotherapy in Subjects with Previously Untreated Unresectable or Metastatic Melanoma. Sponsor Protocol No. CA209067. WIRB Protocol No. 20130618
Gonzalez, Rene13-2193
A Double-Blind, Placebo-Controlled, Single Ascending Intravenous Infusion Study of rHIgM22 in Patients with Multiple Sclerosis. Sponsor Protocol No. IM22-MS-1004. WIRB Protocol No. 20130406
Vollmer, Timothy13-2203
A multinational, multicenter, randomized, double-blind, parallel-group, placebo-controlled study followed by an active treatment period, to evaluate the efficacy, safety and tolerability of two doses of oral administration of laquinimod (0.6 mg/day or 1.2 mg/day) in subjects with relapsing remitting multiple sclerosis (RRMS) Sponsor Protocol No. LAQ-MS-305 (CONCERTO). WIRB Protocol No. 20130631
Vollmer, Timothy13-2209
A Phase 3, Multicenter, Double-Blind, Placebo-Controlled, Single-Treatment Efficacy and Safety Study of MYOBLOC® (Part A) Followed by Open-Label, Multiple-Treatment with MYOBLOC® (Part B) in the Treatment of Troublesome Sialorrhea in Adult Subjects. Sponsor Protocol No. SN-SIAL-301. WIRB Protocol No. 20131152
Klepitskaya, Olga13-2237
Evaluation of Bimatoprost 0.01% and Bimatoprost 0.03% in Patients with Glaucoma or Ocular Hypertension. Sponsor Protocol No. 192024-081. WIRB Protocol No. 20131409
Kahook, Malik13-2240
A Phase 1/2, First-In-Human, Double-Masked, Placebo-Controlled, Dose-Escalation Study Evaluating the Safety, Tolerability, and Efficacy of RU-101 Ophthalmic Solution in Patients with Severe Dry Eye. Sponsor Protocol No. RU-101-C001. WIRB Protocol No. 20131219
Davidson, Richard13-2241
A Multicenter, Open-Label, Extension Study to Evaluate the Long-Term Safety and Efficacy of BIIB019, Daclizumab High Yield Process (DAC HYP), Monotherapy in Subjects With Multiple Sclerosis Who Have Completed Study 205MS301. Sponsor Protocol No. 205MS303. WIRB Protocol No. 20131532
Miravalle, Augusto13-2243
A RANDOMIZED, DOUBLE-BLIND, PLACEBO-CONTROLLED, DOSE-RANGING, MULTICENTER STUDY TO ASSESS THE EFFICACY AND SAFETY OF RIFAXIMIN SOLUBLE SOLID DISPERSION (SSD) TABLETS FOR THE PREVENTION OF COMPLICATIONS IN SUBJECTS WITH EARLY DECOMPENSATED LIVER CIRRHOSIS. Sponsor Protocol No. RNLC2131. WIRB Protocol No. 20131309
Forman, Lisa13-2245
A Follow-up Study to Assess Resistance and Durability of Response to AbbVie Direct-Acting Antiviral Agent (DAA) Therapy in Subjects Who Participated in Phase 2 or 3 Clinical Studies for the Treatment of Chronic Hepatitis C Virus (HCV) Infection. Sponsor Protocol No. M13-102. WIRB Protocol No. 20131190
Everson, Greg13-2249
A Multicenter, Open-label BMN 110 US Expanded Access Program (BMN 110 US EAP) to Provide BMN 110 to Patients Diagnosed with MPS IVA. Sponsor Protocol No. 110-503. WIRB Protocol No. 20130460
Thomas, Janet13-2262
Clinical Outcomes Assessment of the MitraClip Percutaneous Therapy for Extremely High Surgical Risk Patients (The COAPT Trial). Sponsor Protocol No. 11-512. WIRB Protocol No. 20120840
Brieke, Andreas13-2266
A Phase 2, Multicenter, Open-Label STudy to Investigate the Safety and Efficacy of Sofosbuvir/Ledipasvir Fixed-Dose Combination + Ribavirin Administered in Subjects Infected with Chronic HCV who have Advanced Liver Disease or are Post-Liver Transplant. Sponsor Protocol No. GS-US-337-0123. WIRB Protocol No. 20131329
Everson, Greg13-2272
A multicenter, randomized, double-blind, parallel-group, placebo-controlled variable treatment duration study evaluating the efficacy and safety of Siponimod (BAF312) in patients with secondary progressive multiple sclerosis. Sponsor Protocol No. CBAF312A2304. WIRB Protocol No. 20130508
Corboy, John13-2286
AN OPEN-LABEL, MULTICENTER, FOLLOW-UP STUDY TO EVALUATE THE LONG-TERM SAFETY AND EFFICACY OF BRIVARACETAM USED AS ADJUNCTIVE TREATMENT IN SUBJECTS AGED 16 YEARS OR OLDER WITH EPILEPSY. Sponsor Protocol No. 2010-020345-27. WIRB Protocol No. 20101907
Strom, Laura13-2308