|Cognitive Dysfunction in Parkinson's Disease|
This research study plans to use simultaneous brain scans and memory tasks to see if stimulating certain areas of the brain improves thinking and memory. This is not a treatment study
Healthy males over 50 with Parkinson's disease on stable doses of medication and have no metal in the body (dental work may be ok).
|EFFECTS OF TESTOSTERONE THERAPY IN YOUNG ADOLESCENTS WITH KLINEFELTER SNDROME (47.XXY)|
This study will study the effects of testosterone therapy on behavior, mood, problem solving, attention span, and motor skills in adolescent males with Klinefelter syndrome in early puberty. During this period in early puberty there is a lot of variability in how and when doctors start testosterone therapy. This study will evaluate if there are benefits to starting testosterone therapy in early puberty.
Participants with Klinefelter syndrome in early puberty (around age 10-15).
|Join a research study that helps you lose weight and become more fit!|
Seeking volunteers for a research study testing muscle lipid metabolism and diabetes risk before and after a weight loss and exercise training intervention.
BMI over 30
Male or female
|Managing Celiac Disease May Be More Than a Gluten-free Diet|
The CeliAction Study is a clinical research study designed to evaluate the safety and effectiveness of an investigational medication for people with celiac disease.
Diagnosed with celiac disease
On a gluten-free diet for at least 11 months
Have experienced at least one moderate or severe celiac symptom in the past month
|Are you interested in losing weight?|
Volunteers needed for a research weight loss study to examine the
neuronal and behavioral changes that occur with different weight loss
interventions (weight loss surgery or diet).
- Are 21-65 years old
- Have no metal in your body
- Maintained your current weight for the last 6 months
- Weigh 350 pounds or less
- Have a body mass index of 35 or higher
(check it out at http://nhlbisupport.com/bmi/)
|Are you interested in a supervised weight loss intervention?|
Volunteers needed for a research weight loss study to examine the neuronal and behavioral changes that occur with different
weight loss interventions.
- 21-65 years old
- Non- smoker
- Non- Diabetic
- Exercise no more than 1 time a week
- Maintained your current weight for the last 6 months
- Have a body mass index of 30 -40
(check it out at http://nhlbisupport.com/bmi/
|Are you a Parkinson's patient not requiring symptomatic treatment with drugs?|
This research study explores the effects of an FDA approved drug on Parkinson's disease.
Recently diagnosed Parkinson's patients who are not taking any drugs for symptomatic relief or are willing to go off drugs for the duration of the study with neurologist approval. We are also looking for healthy control participants.
|The Health Influences in Puberty "HIP" study|
Research study about puberty and risk for type 2 diabetes
Healthy boy between 11 and 13 years of age
Healthy girl between 9 and 11 years of age
|Volunteers with Alzheimer’s Disease Needed for Memory Study|
To examine the safety and efficacy of the study drug, Sargramostim (Leukine®), on memory in adults with Mild-to-Moderate Alzheimer’s Disease.
1. Age 55 to 85 years;
2. Should have a mild-to-moderate Alzheimer's Disease diagnosis (Mini-Mental State Examination 10-26 inclusive);
3. If on anti-dementia treatment should be on stable treatment for at least 2 months (i.e. cholinesterase inhibitor and/or Memantine or Axona);
4. Stable on all other medications for at least 30 days prior to screen;
5. Should be fluent in English;
6. Should be physically able to participate by medical history, clinical exam and tests;
7. Should have a study partner to accompany them to scheduled visits.
|Healthy Hispanic Female Adults Needed|
For brain imaging research study on how the brain works with we taste sweets. Your participation could help us to develop treatments and preventive measures for anorexia nervosa and obesity
Healthy females 22 to 29 who are right-handed, free of medication with no serious medical conditions, permanent metal implants or braces/retainers, and are at a healthy body weight.
|Do you have high blood pressure?|
Researchers at the University of Colorado Hospital are conducting a research study to help predict if blood pressure medications will work for you.
Subject must be between 30 and 75 years of age and have a diagnosis of uncontrolled hypertension (high blood pressure). As part of the study, you may be eligible for free medication and free clinic visits to check your blood pressure
|Type 2 Diabetes and Exercise Research Study|
To research the effects of an investigational drug on
exercise capacity and blood vessel function.
Person 30-60 with Type 2 diabetes who exercise vigorously less than one hour per week and have normal blood pressure. Must not have smoked for at least one year and have a BMI between 25-39.9.
|Volunteers with Chronic Kidney Disease needed for a Uric Acid Lowering Research Study|
To understand the effect of lowering serum uric acid levels on vascular function in individuals with CKD by comparing Allopurinol therapy and a placebo.
Persons 18+ with moderate chronic kidney disease (CKD stage III) with estimated glomerular filtration rates between 30-60 mL/min/1.73m2
|Research Study: "Anxiety Risk in Teens"|
To learn more about risk factors for anxiety in adolescents with cyclic vomiting syndrome.
Adolescents 13-18 who have been diagnosed with either an anxiety disorder or cyclic vomiting syndrome
|Are you interested in learning about how your breast milk helps your baby grow?|
To find out how maternal size and diabetes status affect her breast milk
To find out what unique parts of breast milk may affect how infants grow.
To learn how to ensure infants receive the best nutrition possible
Women 20-35 who are at least 28 weeks into their pregnancy and planning on exclusively breastfeeding their infant for at least 4 months and delivering at University of Colorado Hospital.
|Free Family Therapy for Youth with Mood Problems|
Helping youth and their families understand and cope with mood swings, develop plans for preventing moods from getting worse, communicate more effectively and solve family problems
Youth between 9-17 who has recently had significant mood swings, has at least one parent with bipolar disorder and does not abuse alcohol or substances. Must agree not to participate in family therapy with another provider for the first year.
This study will look at the body's immune response (how the body fights infection) to the onset of genital herpes. 1-2 study visits for blood draws over the course of 3 months.
18+ years of age; have developed an outbreak of genital herpes within the last 10 days.
|Seeking Children Ages 3 to 17 with NO History of Allergies, Eczema or Asthma|
The goal of this study is to determine why some individuals with atopic dermatitis are at increased risk for skin infections.
Between the ages of 3-17
No history of allergies, eczema or asthma
|Induction of Labor at 39 Weeks Pregnant versus Expectant Management|
Pregnant women are invited to participate in a research study which plans to learn more about whether coming to the hospital and having your labor started with medicine (ie., labor induction) at 39 weeks of pregnancy can improve the baby's health at birth when compared with waiting for labor to start on its own.
First pregnancy (no previous pregnancy beyond 20 weeks)
Single baby (not twins or triplets)
Planning to deliver vaginally and are at least 34 weeks pregnant
Plan to deliver at University of Colorado Hospital or Denver Health Hospital
|Pregnant Participants Needed: A Phase II, Multicenter, Randomized, Observer-Blind, Controlled Study to Evaluate Safety and Immunogenicity of a Trivalent Group B Streptococcus (GBS) Vaccine in Healthy Pregnant Women|
Pregnant women are invited to participate in a research study which plans to learn about antibody (substance produced by the body to fight disease) levels in mothers and infants whose mothers have received the GBS vaccine between 24-34 6/7 weeks of their current pregnancy. the study will also look at antibody levels in mother's breast milk.
Healthy pregnant woman 18-40 years of age
24 0/7 through 34 6/7 weeks pregnant
Planning to breastfeed for at least 90 days after delivery
Plan to deliver at University of Colorado Hospital
|Healthy Volunteers Needed|
The Department of Neurology is looking for healthy volunteers
to participate in a research study examining blinking and
spasms in people with Blepharospam compared to healthy
- Between the ages of 50-80 - Must not have any metal in your body - In good general health
|Healthy Volunteers Needed for a research study of drug levels in blood and hair.|
This study plans to learn more about how tenofovir and emtricitabine (Truvada) build up in cells in blood and hair. Participation will include two 12 week dosing periods separated by a 12 week washout period (total duration is 36 weeks). Eligible participants will be given the supply of medications for the study.
Subject is age 18 to 50 years
Subject is ambulatory
Subject is able to comply with directly observed dosing procedures, including use of audio-visual streaming technology
Subject is able to give informed consent
Subject has a minimum scalp hair length of 2 cm in the occipital region.
Subject is NOT pregnant, planning to become pregnant, or currently breastfeeding
Subject is low risk for HIV-1 infection
Subject does NOT have any active psychiatric illness(es), social condition(s), or alcohol/drug abuse
Subject does NOT have history of non-traumatic, pathologic bone fractures
Subject does NOT have any medical conditions that alter red blood cell kinetics
Subject does NOT have any uncontrolled medical conditions that would interfere with the study conditions
Subject does NOT have contraindicated concomitant medications
|Overweight? Women with a BMI of 30-40 needed for a birth control research study!!|
The University of Colorado School of Medicine’s Department of OB/GYN is
seeking healthy volunteers for a research study of a new birth control pill.
Eligible participants must:
- Have a BMI 32-40
- Be 21-35 years old
- Have regular menstrual cycles
|Research Participants Needed|
We are looking for healthy participants to serve as a standard for comparison
when describing physical function outcomes before and during prosthetic rehabilitation.
1) 50-85 years of age.
2) Able to walk continuously without assistance (i.e., do not use a cane or walker) for 10
minutes and physically active (e.g., participate in recreational activities like walking,
3) No neurological, vascular or cardiac problems that limit function.
4) Body mass index
|Do you have Parkinson's Disease?|
To explore the effects of different doses of endurance exercise in people with PD.
Persons 40-80 who have been diagnosed with Parkinson's Disease and are not yet taking medication or plant to start medication within the next 6 months. You must be willing to begin the exercise program immediately or after a delay of 6 months and willing to do aerobic exercise on a treadmill.
|Do you have Atopic Dermatitis (Eczema)?|
Males and Females between 3 and 80 who have atopic dermatitis or males and females between 8 months and 80 who have a history of, or an active case of eczema hereticum (wide-spread herpes skin infection along with atopic dermatitis.
|Better Control of Type 2 Diabetes May Decrease Your Risk for Cardiovascular Disease.|
To look at the use of an extended release formula of Exenatide compared to a placebo to maintain normal glucose levels. Ultimately to see better control of diabetes and a decrease in cardiovascular disease events.
Person 18+ with Type 2 Diabetes and take no more than 2 diabetes medications with stale doses for the last 3 months. Must not have a planned or anticipated revascularization procedure, but may have a history of cardiovascular disease and must see your primary care physician at least twice a year.
|Are you a Non-smoking Adult between the ages of 45 and 85?|
We are interested in learning more about smoking related lung disease, and need healthy non-smoking participants.
45-85 years old
Non-Hispanic White or African American
No smoking history
No evidence of lung disease
Doctors at the National Institutes of Health are conducting a research study (IRC-004) to investigate whether treating the flu decreases the amount of virus we can detect in your nose, and to understand whether the change in the amount of virus is associated with changes in your symptoms.
Volunteers may be male or female and must:
-be at least 18 years old
-have a history of an influenza-like illness
-have an onset of illness within the past 48 hours
-test positive for influenza
|Alterations in Lung Microbiome in Acute and Chronic HIV Infection|
This is a prospective, observational cohort study. Three groups (A1, A2, and B) will be enrolled in parallel.
-Men and women >/= 18 years.
-Willing to follow all research requirements
-Willing to provide written informed consent
-Group A1- acute HIV infection defined as a high risk HIV exposure within the prior 30 days, or recent HIV-1 seroconversion defined as those with a high risk HIV-1 exposure
-Group A2- healthy controls: HIV-1 seronegative with no high risk HIV-1 exposure in the prior 30 days and no chronic medical illness
-Group B- HIV-1 infection diagnosed by a previous positive antibody or PCR test have been recommended to initiate HAART by their health care provider
You should not be in this study if you are a pregnant or planning to become pregnant.