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Clinical Trials

Volunteer to Be Part of a Research Study

Page through all School of Medicine clinical and research trials below. There are two categories:

  • Detailed Trial Descriptions, submitted by researchers, includes trial specifics and contact information.

  • Additional Clinical Trials, which include basic study details. To contact the researcher either Google the PI (primary investigator) name or use our campus directory.

If you are a researcher seeking volunteers and your study is not posted, please
submit your Web ad here.
  

Detailed Trial Descriptions

 Results From Research and Clinical Trials : Selected site
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COMIRB Approved Advertisement TitleStudy GoalsEligibility CriteriaDate PostedCategory
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Investigations in Gestational Origins of Lifetime Development: Understanding health begins before birth. Are you in your first trimester of Pregnancy?
To learn more about how your metabolism is connected to your baby's growth and development
  • Healthy Women ages 18-35 who are 10-14 weeks pregnant with single baby.  With a  BMI of 30-38 who are willing to complete 5 visits during pregnancy and agreeable to an infant blood draw at birth and DXA postpartum.  
There is an option to take part in a 1 year follow-up which entails an additional 4 visits and another DXA at 1 year of life.
9/28/2016 
We are Currently Enrolling People with Down syndrome for a study in Dr. Pelak's Brain and Vision Research lab at the University of Colorado Anschutz Medical Campus.
To examine visual brain function in people with mild memory impairments to detect early signs of Alzheimer's Disease.​
Persons 19-30 who have Down Syndrome
9/28/2016 
EMERALD STUDY: Effects of MEtformin on CardiovasculaR function in AdoLescents with Type 1 Diabetes
​To determine the effects of Metformin on Cardiovascular Function in Adolescents with Type 1 Diabetes.
  • Persons 12-21 who have Type 1 Diabetes
  • Non-smoker, able to ride a stationary bike
  • You must be willing to take metformin or placebo (sugar pill) for 3 months.
  • Other exclusions apply, please contract study for more information
9/28/2016 
Non-Alcoholic Fatty Liver Disease and Obstructive Sleep Apnea: Mechanistic Links between Hypoxemia and Liver Injury
To learn if obstructive sleep apnea and low oxygen levels have a role in developing Non-Alcoholic Fatty Liver Disease (NAFLD).​​​
Children 10-17 who have a normal weight and no serious medical problems
9/28/2016 
Exercise and Cancer Prevention Research Study
The goal of this study is to better understand the biological mechanisms associated with exercise and reduced risk for breast cancer.
  • You must be a female between the ages of 30-45 to participate in this study. 
  • You must be planning to live in the Denver metropolitan area for the next 10 consecutive months. 
  • You should not be a regular exerciser because this study is for people who do not exercise right now; however, you should be willing to participate in an exercise program 4 times per week for 16-weeks.
9/28/2016 
Are you interested in a supervised exercise intervention?
Volunteers are needed for a research study to examine the effects of exercise on food intake and appetite regulation.
  • 21-45 years old
  • Non- smoker
  • Non- Diabetic
  • Exercise no more than 1 time a week
  • Maintained your current weight for last 6 months
  • Have a body mass index (BMI) of 27-35 (check it out at http://nhlbisupport.com/bmi/)
9/28/2016 
Study of Mood Disorder in Preschool Children
We are doing a research study to better understand what mood disorders look like in preschool children.
We are looking for volunteers who:  
  • Are parents of children between the ages of 4 and 6 years 0 months.
  • Are in one of three groups:
    1. Their child has no major mental health problems, and there is no family history of major mood or psychotic disorders.
    2. Their child has been diagnosed with a mood disorder, bipolar disorder, or mood dysregulation disorder. 
    3. Their child has been diagnosed with attention deficit hyperactivity  disorder (ADHD).  
  • Parents or guardians will be asked to:
    • Read and sign a consent form
    • Participate in interviews about their children
  • The  children will be asked to:
    • Participate in a story game
    • Take tests of verbal and nonverbal abilities
How much time will this take?
The visit for the child will last from 1 to 2 hours.  The visit for the parents will last 3 to 5 hours.
9/28/2016 
Understanding how Tysabri and Gilenya Influence the Quality of your Daily Life with Multiple Sclerosis
The purpose of this research study is to compare two medications, Tysabri and Gilenya, used in the treatment of multiple sclerosis (MS), through a few self-reported patient surveys. We will ask you to complete online surveys about overall health-related quality of life, disability, fatigue, cognition and productivity. We will also want to review your medical records to understand your MS history with your permission. This study will help us understand how these drugs are impacting each aspect of your daily lives.
  • Between ages 16 and 65
  • Scheduled to start natalizumab or fingolimod for the first time to treat your MS
9/28/2016 
Living with MS?
To evaluate the safety of a new investigational drug that may help reduce relapses.
  • Between the ages of 18 to 65
  • Participants must have relapsing-remitting multiple sclerosis (RRMS)
9/28/2016 
Are you Pregnant or a Nursing Mother? Consider being a part f a Breast Cancer Research.
This study will examine changes that occur in the breast tissue, blood and urine of a woman after she has given birth to a child. The study will examine how a woman’s breast and her cells change after pregnancy and breast feeding and how her immune system interacts with these changes. The immune system is a complex network of cells that identify our tissues as “self” or “foreign” as well as normal cells or cancer cells. We hope to discover how a woman’s breast changes after pregnancy or breast feeding to see if this time point in a woman’s life could be targeted to prevent breast cancer.
You are being asked to be in this research study because you are pregnant or were recently pregnant and have not had breast cancer or another autoimmune disease.
9/28/2016 
Do You have type 1 diabetes?
To learn more about an investigation study drug
    • Persons 18 to 30 years who have had Type 1 Diabetes for 12 months
    • Have a stable insulin treatment (MDI or pump) 3 months and an A1C 9.0
    • Not using an antidiabetic agent other than insulin or insulin analogue
    • Willing to take study drug or placebo pills daily for 3 months
    • Not pregnant, breast-feeding or intending to become pregnant
    • Other inclusion/exclusions apply, please contact study coordinator for more information
 
9/28/2016--Select a Category--
Will You Be a Caregiver For Your Loved One During Transplant?
We are conducting a research study to assess treatments to reduce the effects of stress on caregivers of patients experiencing an allogeneic transplant.
Patient inclusion criteria include: 1) receiving an allogeneic HSCT, 2) able to read and speak English, 3) telephone access. Caregiver inclusion criteria include: 1) the person in the patient's life who is primarily responsible for care decisions, emotionally invested in the patient's care, provides instrumental care such as transportation, and available if randomized to the fPER group to participate in the majority of intervention sessions, 2) able to read and speak English, 3) willingness to use a Smartphone, 4) absence of a serious medical condition likely to influence hair cortisol, 5) no steroid medications, and 6) over the age of 18 years.
9/28/2016Cancers and Other Neoplasms
DO YOU HAVE GESTATIONAL DIABETES? Would you like help with your GDM Diet?
Research Subjects Needed to Participate in a Diet Research Study in Women with Gestational Diabetes
Who can qualify? * Highly motivated pregnant women with Gestational Diabetes not taking medicine for blood sugar control * Women willing to follow 1 of 2 healthy diets for blood sugar control * Women willing to complete 6 visits during pregnancy with infant follow up * Gestational age: <31 weeks; singleton pregnancy * Healthy  women, age : 20-36 years * No high blood pressure * Overweight or Obese
9/28/2016Nutritional and Metabolic Diseases
Volunteers needed for a NASH therapeutic trial
Clinical research study of an investigational product for the treatment of non-alcoholic steatohepatitis (NASH)
*≥18 years old *Confirmed diagnosis of NASH *No other liver disease *No excessive alcohol use (no more than 2 drinks/day for women and 3 drinks/day for men)
9/28/2016--Select a Category--
We are looking for adolescents who have received a solid organ transplant for a telehealth group research study!
Learning how to improve adherence in adolescents who have received solid organ transplants and determining whether telehealth can be used to facilitate groups for teenage transplant recipients.
Teens between the ages of 13 and 17 who have received a heart, liver, or kidney transplant.
9/28/2016--Select a Category--
We are looking for Healthy Men and Women to participate in the WATCH CALORIE Research Study
The study will examine how diet impacts circadian clocks in abdominal fat tissue
Healthy women aged 20 to 35 years A BMI between 25- 30 Exercise less than 4 days per week Have a regular sleep schedule
9/28/2016Nutritional and Metabolic Diseases
Study of Pre and Postnatal Infant Brain Growth and Development
Through a study of infants before and after pregnancy, researchers at Children's Hospital Colorado and the University of Colorado Denver will investigate the impact of mother and infant nutritional health on infants' cognitive development.
* That mom (you) was at least 18 when you had your child. * Delivered full term (at least 37 weeks).  * English speaking (as one of the household languages). * Your child was part of a singleton pregnancy.  * No abnormalities found on the fetal ultrasound and no serious complications during delivery.  * No smoking, drinking, recreational drug use or prescription drug abuse during pregnancy. * No diabetes before or during the pregnancy.  * No high blood pressure before or during the pregnancy.  * No metal in or on your child’s body that would make it unsafe for him/her to have an MRI scan. 
9/28/2016--Select a Category--
Heavy periods affecting your life? You have options.
The purpose of this study is to better understand the causes of heavy menstrual bleeding and to identify women who are suitable candidates for an endometrial ablation procedure. Endometrial ablation is a procedure designed to reduce or even stop menstrual bleeding.
a. Between 25-50 years of age b. Heavy menstrual bleeding c. Have not given birth in the last 6 months, are not currently pregnant, and do not wish to become pregnant in the future.
9/28/2016Urinary Tract, Sexual Organs, and Pregnancy Conditions
Help Us Learn More about Care Decisions at End-of-Life . . . A Hospice Decision-Making Research Project
The goal of this project is to conduct a needs assessment to learn what information patients, providers and informal caregivers think should be included in hospice decisional support materials.
-Cared for a loved one with advanced illness -Have lots of illnesses or advanced illness? -Have you or a loved one considered hospice -Are you willing to participate in a focus group and/or personal interview to share your experiences and opinions about major decisions near the end of life? OR -Are a doctor, nurse, social worker, clergy member or another professional that works with seriously ill patients -Do you volunteer with hospice or with patients making end-of-life care decisions? -Do you have experience with referring patients to hospice? -Do you have experience caring for patients in hospice? -Do you have experience caring for patients near death? -Are you willing to participate in a focus group and/or personal interview to share your experiences and opinions about major decisions near the end of life?
9/28/2016--Select a Category--
Type 2 Diabetes and Exercise Research Study
Perceived exertion during exercise
Person 50-70 with or without Type 2 diabetes who exercise vigorously less than one hour per week and have normal blood pressure.  You should have a BMI between 25-35 and have not smoked for a least one year.
9/27/2016 
Participants Ages 12-15 years old Needed for Research Study
To learn about how children with absence epilepsy compare to healthy children in areas such as behavior, neuropsychological skills and quality of life.
Healthy hispanic individuals who are 12-15 years; No history of seizures, seizure like episodes, neurological diseases or a loss of consciousness greater than 5 minutes in their immediate family
9/27/2016 
MRI and Questionnaire Research Study for Patients with MS Taking Tysabri and Healthy Controls
This research study plans to learn more about the differences in brain scans and self-reported quality of life between MS patients taking natalizumab (Tysabri) and individuals without MS.
A relapsing Multiple Sclerosis patient 18-55 years old who has been taking Tysabri (natalizumab) for at least 2 years

OR

A healthy individual 18-55 years old without Multiple Sclerosis or other neurological conditions
9/27/2016 
Participants Needed for an Exercise Study for People with Multiple Sclerosis
Researchers from the Neurophysiology of Movement Laboratory on the University of Colorado Boulder campus and the Multiple Sclerosis Center on the University of Colorado Anschutz Medical Campus are conducting a study to investigate the capacity of neuromuscular electrical stimulation to improve walking in persons with multiple sclerosis.
-Between 18 to 55 years of age -Have clinically confirmed diagnosis of MS -Are able to talk but have some difficulty walking
9/27/2016 
Help test a mobile app for postpartum moms
This research study will test a mobile application to learn more about how to best deliver information about diet and physical activity for postpartum women at elevated risk for diabetes and heart disease.
You may qualify for this study if you:  Are between 18-45 years old  Are in your third trimester of pregnancy or have given birth in the last 24 weeks  Have a postpartum BMI: 25-45 kg/m2  Have access to and be willing to use a wi-fi enabled iPhone or an iPod  Have a history of one or more of the following complications in your most recent pregnancy: o Gestational diabetes mellitus o Preeclampsia o Gestational hypertension o Pre-term delivery (32-37) weeks o Small for gestational age (
9/27/2016 
Healthy Individuals needed for Genetic Study of Granulomatous Interstitial Lung Disease.
To investigate genetic factors associated with the disease sarcoidosis.
Must be 18 years or older with no history of chronic lung disease (including asthma) or connective tissue/rheumatological disease. Participants must complete a questionnaire and have a small blood draw.
9/27/2016Respiratory Tract (Lung and Bronchial) Diseases
We are seeking physically active women and men for a research study on PTH and Calcium Responses to Exercise (PACE) in Older Adults
To determine 1) if sweating rate during exercise affects the decrease in blood calcium level, and 2) if this causes an increase in a hormone called parathyroid hormone or PTH that causes bone to release calcium.
 A 60-80-year-old woman or man in generally good health  Often walk for exercise and can walk for an hour at a time  Not taking osteoporosis medication  No history of Diabetes or Cardiovascular Disease
9/27/2016--Select a Category--
Social Networks of Abused Prescription Pills in Youth (SNAPPY) Research Study
The purpose of this research study is to learn more about the misuse of prescription pills and the risk for injection drug use.
You may be selected to participate in the study if you are: • Between the ages of 15 and 24 • Willing to provide information about people in your life and things you do with them • Currently using prescription opioids without a doctor’s prescription or in ways other than what was prescribed OR • Currently using heroin after a period of misusing prescription opioids
9/27/2016Substance Related Disorders
We are seeking physically active men for a research study on PTH and Calcium Responses to Exercise (PACE)
This study will determine how much calcium enters and leaves the blood during exercise.  The results of this study will help us find out why some adults who exercise a lot sometimes have low bone density
• Men in generally good health, aged 18-45 years • Regularly cycle for exercise and can ride for an hour at a vigorous intensity • Not taking medication for osteoporosis • No history of asthma
9/27/2016Muscle, Bone, and Cartilage Diseases
Women with Obesity Needed!
For brain imaging research study on how the brain works with we taste sweets. Your participation could help us to develop treatments and preventive measures for anorexia nervosa and obesity
Females 18 to 25 years old who are right-handed, currently overweight, have a body mass index (BMI) over 30, and no permanent implants or braces
9/27/2016Behaviors and Mental Disorders
A Study to Evaluate Dolutegravir plus Lamivudine Dual Therapy for the Treatment of Naive HIV-1-Infected Participants
The main purpose of this study is to evaluate how well a two-drug combination of study drugs (dolutegravir plus lamivudine) will suppress HIV at 24 weeks after starting treatment. The study will also look at the safety and tolerability of this study drug combination, and factors that may affect how well it works in different individuals.
-HIV-1 infected men and women at least 18 years of age -Have not taken HIV medications (except for successful prevention of HIV infection) -No evidence of resistance to the type of anti-HIV drugs being used in the study -Have blood HIV level (viral load) of at least 1000 copies/mL but less than 500,000 copies/mL -No active Hepatitis B infection
9/27/2016Viral Diseases

​Additional Clinical Trails

 Results From Research : Selected site
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RANDOMIZED PHASE III COMPARISON OF STANDARD DOSE (60 GY) VS HIGH DOSE (74 GY) CONFORMAL RADIOTHERAPY WITH CONCURRENT AND CONSOLIDATION CARBOPLATIN/PACLITAXEL +/- CETUXIMAB IN PATIENTS WITH STAGE IIIA/IIIB NON SMALL CELL LUNG CANCER
Kavanagh, Brian D07-0851
NEW TRENDS IN HIV-RELATED RISKY PATTERNS OF INJECTING DRUG USE AND DRUGS DISTRIBUTION IN FOUR EURASIAN COUNTRIES WITH SUBSTANTIAL PRESENCE OF ATDS
Booth, Robert E08-1117
Helping Ourselves, Helping Others: The Young Womens' Breast Cancer Study
Borges, Virginia F. M.D.08-1222
S0931, "EVEREST: EVErolimus for Renal Cancer Ensuing Surgical Therapy, a Phase III Study"
Lam, Elaine Tat M.D.11-0545
GOG 9923 - A PHASE I STUDY OF INTRAVENOUS CARBOPLATIN/PACLITAXEL OR INTRAVENOUS AND INTRAPERITONEAL PACLITAXEL/CISPLATIN IN COMBINATION WITH CONTINUOUS OR INTERMITTENT / /CTEP SUPPLIED AGENT ABT-888 (NSC #737664) AND CTEP-SUPPLIED AGENT BEVACIZUMAB (NSC #704865) IN NEWLY DIAGNOSED PATIENTS WITH PREVIOUSLY UNTREATED EPITHELIAL OVARIAN, FALLOPIAN TUBE OR PRIMARY PERITONEAL CANCER
Guntupalli, Saketh Ram11-0636
A Phase II Study of the Aurora and Angiogenic Kinase Inhibitor ENMD-2076 in Previously Treated Locally Advanced and Metastatic Triple-Negative Breast Cancer
Diamond, Jennifer R M.D.11-0684
Identifying Unique Risks to Pregnancy In Perinatally Infected HIV Positive Women
Weinberg, Adriana11-1653
Oncofertility Patient Registry
Kondapalli, Laxmi A12-0389
An International Phase 3, Randomized Trial of Autologous Dendritic Cell Immunotherapy (AGS-003) Plus Standard Treatment of Advanced Renal Cell Carcinoma (ADAPT)
Lam, Elaine Tat M.D.13-1546
A phase II study of ponatinib in cohorts of patients with lung cancer preselected using different candidate predictive biomarkers.
Camidge, David Ross MD, PhD13-2002
A Phase 2B Randomized, Controlled, Multicenter, Open-Label Study of the Efficacy and Immune Response of GVAX Pancreas Vaccine (with Cyclophosphamide) and CRS-207 Compared to Chemotherapy or to CRS-207 Alone in Adults with Previously Treated Metastatic Pancreatic Adenocarcinoma
Weekes, Colin Dexter13-3144
Vascular mechanisms for the effects of loss of ovarian hormone function on cognition in women
Hildreth, Kerry L. MD14-0193
A Randomized, Double-Blind, Placebo-Controlled, Parallel-Group Study Assessing the Effect of Gelesis100 on Body Weight in Overweight and Obese Subjects with and without Type 2 Diabetes. Sponsor Protocol No. G-04. WIRB Protocol No. 20150046
Hill, James O PhD14-0383
Reclaim Deep Brain Stimulation Therapy for Obsessive-Compulsive Disorder
Abosch, Aviva M.D.14-0554
A Phase I Trial of Inhaled Iloprost for the Prevention of Lung Cancer in Former Smokers
Miller, James York E M.D.14-1247
LIBERTY 360: Prospective, Observational, Multi-Center Clinical Study to Evaluate Acute & Long Term Clinical & Economic Outfomes of Endovascular Device Intervention in Patients with Distal Outflow Peripheral Arterial Disease (PAD)
Armstrong, Ehrin14-1522
Multicenter, open-label, randomized, controlled phase III clinical study of the efficacy and safety of photodynamic therapy using porfimer sodium for injection as treatment for unresectable advanced perihilar cholangiocarcinoma Sponsor Protocol No. PIN-PHO1201 WIRB Protocol No. 20140456
Shah, Raj Jay M.D.14-1650
Functional Avoidance Radiation Therapy for Lung Cancer Patients
Vinogradskiy, Yevgeniy14-1856
Self-reported usage patterns of opioid analgesic medications after surgery
Bartels, Karsten14-1938
Pilot study of a surgery and chemotherapy-only approach in the upfront therapy of children with WNT positive standard risk medulloblastoma
Dorris, Kathleen McCarthy O'Toole14-2097
Analysis of cataract surgery outcomes performed at the Children's Hospital Colorado from January 2005 through October 2014
Singh, Jasleen14-2183
A PHASE 3B RANDOMIZED STUDY OF LENALIDOMIDE (CC-5013) PLUS RITUXIMAB MAINTENANCE THERAPY FOLLOWED BY LENALIDOMIDE SINGLE-AGENT MAINTENACE VERSUS RITYUXIMAB MAINTENANCE IN SUBJECTS WITH RELAPSED/REFRACTORY FOLLICULAR, MARGINAL ZONE OR MANTLE CELL LYMPHOMA
Bowles, Daniel W14-2282
Protocol for the Evaluation of Dario™ BGMS Performance at Elevated Altitude. Sponsor Protocol No. CP-0003; WIRB Protocol No. 20142637
Garg, Satish K14-2330
Use of Ultrasonic Bone Scalpel in Adolescent Idiopathic Scoliosis - Randomized Clinical Trial
Garg, Sumeet15-0036
A DOUBLE-BLIND, PLACEBO-CONTROLLED RANDOMIZED TRIAL TO STUDY THE VIASKIN MILK EFFICACY AND SAFETY FOR TREATING IgE-MEDIATED COW’S MILK ALLERGY IN CHILDREN (MILES STUDY) Sponsor Protocol No. MILES WIRB Protocol No. 20141789
Fleischer, David Mark M.D.15-0140
ABT-414 Alone or ABT-414 Plus Temozolomide versus Lomustine or Temozolomide for Recurrent Glioblastoma; a Randomized Phase II Study of the EORTC Brain Sponsor Protocol No. MI4-483 WIRB Protocol No. 20142384
Damek, Denise Marie15-0164
A Phase 3, Multicenter, Randomized, Double-Blind, Placebo-Controlled, Parallel-Group Study to Evaluate the Efficacy and Safety of Rivipansel (GMI-1070) in the Treatment of Vaso-Occlusive Crisis in Hospitalized Subjects with Sickle Cell Disease
Hassell, Kathryn L M.D.15-0391
Predicting the Safety and Effectiveness of Inferior Vena Cava Filters (PRESERVE) Sponsor Protocol No. G140045 P WIRB Protocol No. 20150996
Rochon, Paul J M.D.15-0537
Reproductive and Sexual Health Issues in Young Women with CF: A Patient Survey
Sagel, Scott D MD, PhD15-0575
In-Clinic Feasibility Study to Observe the Closed Loop System. Sponsor Protocol No. CEP273/Z25. WIRB Protocol No. 20130443
Slover, Robert H. M.D.15-0684


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