Hypopituitary Control and Complications Study (HypoCCs):
This is an on-going, observational study of patients with pituitary hormonal deficiencies (hypopituitarism) and growth hormone deficiency, who are either on or off growth hormone, to determine the long-term effects of growth hormone deficiency, and its treatment, on health and quality of life.
Sponsor: Eli Lilly
Principal Investigators: Dr. Margaret E. Wierman, Co-investigator Dr. Janice Kerr
To learn more, contact the study coordinator: Suzy Humphrey at 303-724-4156.
Ongoing Basic Science and/or Translational Research:
Understanding Pituitary Tumorigenesis
Sponsor: Veterans Affairs Merit Review
Principal Investigator: Dr. Margaret E. Wierman
Summary: This study analyzes small pieces of pituitary tumors for their molecular gene profiles, compared to normal pituitary, to identify new markers for pituitary tumors and to identify novel candidates that may either cause or be targets for therapy of pituitary tumors in humans.
The Role of a Growth Factor, Wnt10a, in Pituitary Thyrotrope Cells
Sponsor: The National Institute of Health
Principal Investigator: Dr. Janice Kerr
Summary: Pituitary cells that make thyroid-stimulating hormone (TSH) are called thyrotropes, and are critical for several aspects of normal human development and function. The goal of this study is to understand the role of a growth factor, Wnt-10a, in normal and abnormal thyrotrope cell growth.