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Areas of Research

Macromolecular Structure and Function

Macromolecular Structure and Function
Faculty use biophysical and electron microscopic methods to analyze the structure and function of nucleic acids and proteins at the atomic level.
Associated Faculty Members
 Results From Molecular Biology : Selected site and subsites
Faculty NameResearch Description
Barton, David
Enterovirus RNA replication.
Churchill, Mair
Structural biology of gene regulatory mechanisms
Jones, David
How the three-dimensional structure of proteins and nucleic acids controls their biological function. NMR is used to study the structure and dynamics of biological molecules implicated in the development and progression of disease.
Kieft, Jeffrey
RNA structure and plasticity, viral RNA manipulation of host cell machines and enzymes, RNA-protein interactions, ribosome structure and function, use of RNA in engineered nanomachines, development of new tools for structural biology.
Kutateladze, Tatiana
Biochemistry and Structural Biology; determination of the three-dimensional structures of proteins implicated in cancer by NMR spectroscopy and X-ray crystallography; the study of epigenetics and deciphering the histone code; molecular mechanisms of protein-phospholipid interactions; structure-based drug design.
Liu, Changwei
The ubiquitin proteasome pathway.
McMurray, Michael
Mechanisms of assembly and inheritance of dynamic macromolecular structures: Higher-order septin assemblies in budding yeast
Pearson, Chad
Centriole assembly and function
Zhao, Rui
Molecular mechanism of pre-mRNA splicing; drug design targeting transcriptional complex in breast cancer