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Areas of Research

Cancer Biology

Cancer Biology
Faculty study mechanisms of oncogenesis and metastasis including the function of oncogenes, tumor suppressors and cellular interactions with the tumor microenvironment.
Associated Faculty Members
 Results From Molecular Biology : Selected site and subsites
Faculty NameResearch Description
Black, Joshua
Regulation of genome stability, cancer cell heterogeneity and chemotherapeutic responses by the chromatin microenvironment.
Bradford, Andrew
Regulation of tissue specific gene expression in response to hormonal and growth factor stimuli, characterization of fibroblast growth factor signaling in the pituitary, and the role of protein kinase C in endometrial cancer.
DeGregori, James

Cancer - understanding its evolution and targeting its dependencies.

Ernst, Patricia
Hematopoietic Stem Cell Development and Maintenance: The Role of the "Mixed Lineage Leukemia" Gene in Normal Blood Cell Development, Differentiation and Leukemia.
Fantauzzo, Katherine
Receptor tyrosine kinase signaling in mammalian craniofacial development
Ford, Heide
The SIX family of homeobox genes and their role in development, cell cycle control and tumorigenesis.
Gerber, Anthony
The inter-relationship of glucocorticoid receptor signaling, inflammatory response, and lung function.
Gutierrez-Hartmann, Arthur
My laboratory focuses on two main projects: (1) elucidating the molecular mechanisms governing pituitary-specific gene expression; and, (2) determining the role of Ets transcription factors in breast cancer.
Hagman, James
Regulation of B lymphocyte - specific transcription and differentiation
Hu, Cheng-Jun
Role of hypoxic response in tumor progression and metastasis
Huang, Mingxia
Function and regulation of the DNA damage response.
Jordan, Craig
The characterization and targeting of leukemia stem cells.
Liu, Changwei
The ubiquitin proteasome pathway.
Prekeris, Rytis
The role of cell polarity during cell division, epithelial tissue morphogenesis and cancer cell metastasis
Pyeon, Dohun
Human Papillomaviruses (HPVs)
Reyland, Mary
Regulation of apoptosis in epithelial cells by signal transduction pathways.
Sclafani, Robert
The regulation of the eukaryotic cell cycle: DNA replication, repair and checkpoints important in cancer chemoprevention.
Sikora, Matthew
The overall goal of the Sikora Laboratory is to understand mechanisms of response and resistance to steroid hormones and anti-estrogen therapies in breast cancer.
Thorburn, Andrew
Apoptosis regulation in cancer development and treatment.
VanDyk, Linda
Control of growth regulation and differentiation of host cells in viral infection and persistence.
Wang, Jing
Genomic instability and cancer development; molecular mechanisms of somatic hypermutation and class switch recombination; metastasis and genomic instability.
Wang, Xiao-Jing
Head, Neck, and Skin Cancer Research
Transcriptional regulation of mouse embryonic development and the role of transcription factors in mammary gland development and breast cancer.
Zhao, Rui
Molecular mechanism of pre-mRNA splicing; drug design targeting transcriptional complex in breast cancer