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CFReT News & Activities

​​Upcoming Meetings:  

International Society for Heart Research North American Section
ISHR NAS 2020 

May 26-29, 2020

Denver, Colorado

To register click below: 



CFReT Most Recent Publications:

"PTEN (Phosphatase and Tensin Homolog) Protects Against Ang II (Angiotensin II)-Induced Pathological Vascular Fibrosis and Remodeling-Brief Report."

Circulation: Heart Failure

"Coronary Artery Remodeling and Fibrosis With Continuous-Flow Left Ventricular Assist Device Support"

Amrut V. AmbardekarMary C.M. Weiser-EvansMarcella LiSuneet N. PurohitMuhammad AftabT. Brett ReeceKaren S. Moulton​

Full text:​

Science Translational Medicine  

"Histone deacetylase activity governs diastolic dysfunction through a nongenomic mechanism"

Mark Y. Jeong, Ying H. Lin, Sara A. Wennersten, Kimberly M. Demos-DaviesMaria A. CavasinJennifer H. MahaffeyValmen MonzaniChandrasekhar SaripalliPaolo MascagniT. Brett ReeceAmrut V. AmbardekarHenk L. GranzierCharles A. Dinarello and Timothy A. McKinsey

"PTEN deficiency promotes pathological vascular remodeling of human coronary arteries"

Karen S. Moulton, Marcella Li, Keith Strand, Shawna Burgett, Penn McClatchey, Rebecca Tucker, Seth B. Furgeson, Sizhao Lu, Bruce Kirkpatrick, Joseph C. Cleveland, Raphael A. Nemenoff, Amrut V. Ambardekar,and Mary C.M. Weiser-Evans

Full text:

CFReT Publications

"Differentiated Smooth Muscle Cells Generate a Subpopulation of Resident Vascular
Progenitor Cells in the Adventitia Regulated by KLF4",
Mark W. Majesky, Henrick Horita, Allison Ostriker, Sizhao Lu, Jenna N. Regan, Ashim Bagchi, 
Xiu Rong Dong, Joanna Poczobutt, Raphael A. Nemenoff, and Mary C.M. Weiser-Evans (2016) Circulation Research

"Nuclear PTEN functions as an essential regulator 
of SRF-dependent transcription to control smooth 
muscle differentiation", 
Henrick Horita, Christina L. Wysoczynski, Lori A. Walker, Karen S. Moulton, Marcella Li, 
Allison Ostriker, Rebecca Tucker, Timothy A. McKinsey, Mair E.A. Churchill, Raphael A. Nemenoff, 
& Mary C.M. Weiser-Evans (2016) Nature Communications​

"Characterizing fibrosis in UUO mice model using multiparametric analysis of phasor distributionfrom FILM images.", Ranjit S., Levi, M., Furgeson, S., Gratton, E., (2016) Biomed Opt Express

"Label-free fluorescence lifetime and second harmonic generation imaging microscopy improves quantification of experimental renal fibrosis.", 
Ranjit, S., Dobrinskikh, E., Montford, J., Dvornikov, A., Lehman, A., Orlicky, DJ., Nemenoff, R., Gratton, E., Levi, M., Furgeson, S., (2016) Kidney International

"Epigenetic regulation of cardiac fibrosis." Stratton, MS., McKinsey TA., (2016) J. Mol. Cell Cardiology