In Vivo Disease Modeling Unit
The In Vivo Disease Modeling Unit employs
state-of-art, validated rodent models of cardiac, pulmonary, renal, and hepatic
fibrosis to discover novel pathogenic mechanisms and to assess the
efficacy of interventional therapeutics. Organ fibrosis in these models
is triggered by genetic, surgical and/or chemical manipulation, and the high
quality data that are produced enable critical go/no-go decisions about
projects and therapeutic strategies.