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Linda Crnic Institute

Crnic Grand Challenge Grants Program


The Linda Crnic Institute for Down Syndrome, a unit of the University of Colorado housed on both the Anschutz Medical and Boulder campuses, is working to eliminate the ill effects of Down syndrome.  The Institute plans to accomplish this goal by supporting research likely to aid in the understanding of the syndrome and in reducing its adverse consequences.  Exciting new technologies in genomics, proteomics, transcriptomics, genetics, stem cell biology, gene knockouts, microscopy, etc. are enabling novel and powerful approaches to age-old and important questions, and are enabling our Down syndrome community to make significant strides towards these goals.

Generous gifts from the Anna and John J. Sie Foundation and donors to the Global Down Syndrome Foundation, as well as significant support from the CU-Boulder and CU-Denver Chancellors’ Offices, provide funding for grants to initiate research projects on the mechanisms whereby three copies of chromosome 21 lead to Down syndrome and on ways to ameliorate the ill effects in those who currently have Down syndrome. These research grants are available to University of Colorado faculty on either campus who now study Down syndrome or who are interested in initiating projects to do so.  Our purpose is to create a vibrant, exciting and active research community dedicated to solving the key DS-related issues outlined on pages 3 - 5 in the Application Overview Requirements document. The members of the Crnic Institute and our grantees are working together, making the University of Colorado a powerhouse in this area. 

For more information, please email​.