The Linda Crnic Institute at the University of Colorado at Anschutz Medical Center is a top center for research and treatment of Down Syndrome. Run by Edward R.B. McCabe, MD, PhD, the institute is funded by John and Anna Sie Foundation.

Director's Welcome

Welcome to the Linda Crnic Institute for Down Syndrome. As the first full-time executive director of the Crnic Institute, I am extremely pleased with the outstanding team we are building to achieve our mission to significantly improve the lives of all people with Down syndrome and to eradicate the medical and cognitive ill effects associated with Down syndrome.

The Crnic Institute is unique in its comprehensive approach to Down syndrome, moving information nimbly from basic science investigations, clinical and translational research, and clinical trials into the clinic. Our administrative offices, the majority of our laboratory space and our clinical arm, the Anna and John J Sie Center for Down Syndrome at the Children’s Hospital Colorado, are located on the Anschutz Medical Campus. Read more >>