Schenkman M (PI), Corcos D (Co-PI), Kohrt W, Berman B, Robichaud J, Hall D, Comella C, Delitto A, Moore C, Jain S. Exploratory Study of Different Doses of Endurance Exercise in People with Parkinson’s Disease.
This phase II randomized clinical trial is designed to determine parameters of exercise intensity that attenuate progression of symptoms of PD. Upon the completion of this study parameters will have been defined for a phase III clinical trial. National Institutes of Health (NIH) / NINDS. Awarded 2011-2015 ($2.99 million)
Hebert J (PI), Schenkman M (Co-PI), Corboy C, Vollmer T. Vestibular Rehabilitation for Persons with Multiple Sclerosis: Who Benefits the Most? The aims of this study are 1) to study the effects of vestibular rehabilitation for persons with MS who have brainstem and/or cerebellar involvement compared to persons with MS who do not, 2) examine benefits with respect to visual stability (eye movements) and fatigue, and 3) to compare changes in self-reported fatigue based on brainstem and/or cerebellar involvement stratum and between the two study groups. National Multiple Sclerosis Society. Awarded: 2012-2015 ($536,295)
Moss M (PI), Quan D, Nordon-Craft A, Schenkman M. The Diagnosis and Treatment of Critical Care Polyneuromyopathy. Determine whether critical care illness can be identified early and determine the impact of an impact of intensive physical intervention for people with acute respiratory failure who have developed polyneuromyopathy. National Institutes of Health (NIH). Awarded: 2009-2014. ($2.28 million)
Schenkman M (PI), Carollo JJ, Christiansen CL, Davidson BS, Maluf KS, Solomonow M, Stevens-Lapsley J (Co-I). Interdisciplinary Movement Science Laboratory. Academic Enrichment Fund, New Strategic Research Initiative, School of Medicine, University of Colorado Denver. Awarded: 2008-2012 ($245,636)
Recently Completed Grants
National Institutes of Health (Schenkman M)
Exercise intervention for people with Parkinson’s disease
PUBLICATIONS (Selected from the last five years of 74 total)
Christiansen CL, Davidson BS, Schenkman M, Kohrt WM. Muscle co-activation and stride variability: implications for walking economy in people with Parkinsons’s disease. PM&R in press.
Kluger BM, Brown RP, Aerts S, Schenkman M. Determinants of objectively measured physical functional performance in Parkinson’s disease. PM&R in press.
Ellis R, Cress ME, Wood R, Schenkman M. Exploring the relationship between physical activity and participation in older adults with Parkinson’s disease. Topics in Geriatrics Rehabilitation, Accepted for publication.
Nordon-Craft A, Schenkman M, Edbrook L, Malone D, Moss M, Denehy L. The physical function intensive care test: implementation in survivors of critical illness. Phys Ther ePub Ahead of Print: 05/2014; DOI: 10.2522/ptj.20130451.
Ellis T, Schenkman M. The Benefits of Exercise and Physical Activity in Patients with Parkinson Disease. Focus on Parkinson's Disease, Amsterdam 2014;24:21-25.
Moore CG, Schenkman M, Kohrt WK, Delitto A, Hall DA Corcos D. Study in Parkinson Disease of Exercise (SPARX): Translating high-intensity exercise from animals to humans. Contemporary Clinical Trials. 2013; 36: 90-98. DOI information: 10.1016/j.cct.2013.06.002.
Nordon-Craft A, Moss M, Quan D, Schenkman M. Intensive care unit-Acquired Weakness, Implications for physical therapist management. Phys Ther. 2012;92:1494-1506.
Schenkman M, Hall DA, Barón A, Schwartz RS, Mettler P, Kohrt WM Exercise for People in Early and Mid-Stages of Parkinson’s Disease: A 16-month Randomized Controlled Trial. Physical Therapy, 2012;92:1395-1410.
Stevens-Lapsley J, Kluger B, Schenkman M. Quadriceps muscle weakness, activation deficits, and fatigue with Parkinson’s disease. Neurorehabil and Neural Repair. 2012;26:533-541.
Hebert J, Manago M, Corboy J, Schenkman M. The effects of vestibular rehabilitation on MS-related fatigue: a randomized controlled trial. Phys Ther. 2011;91:1166–1183.
Schenkman M, Ellis T, Christiansen C, et al. Profile of Functional Limitations and Task Performance among People with Early and Mid-Stage Parkinson Disease. Phys Ther. 2011;91:1339-1354.
Ene H, McRae C, Schenkman M. Attitudes of people with Parkinson disease toward exercise following participation in an exercise intervention study. JNPT, 2011, 35;34-40.
Schenkman M, McFann K, Barón, AE. “PROFILE PD”: Profile Of Function and Impairment Level Experience with PD. Clinimetric Properties of a Rating Scale for Physical Therapist Practice. JNPT 2010;34:182-192.
Morris ME, Martin CL, Schenkman M. Striding out with Parkinson disease: evidence based physical therapy for gait disorders. Phys Ther 2010;90:280-288.
Christiansen CL, Schenkman ML, McFann K, Wolfe P, Kohrt WM. Walking economy in people with Parkinson&'s disease. Mov Disord. 2009 Jul 30;24(10):1481-7.
Additional publications by Margaret Schenkman