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Department of Psychiatry

Department of Psychology
 

Magnetoencephalography


 

 

MEG Faculty and Staff
Don Rojas, PhD, Director

Peter Teale, MSEE, Electronic Engineer

Eugene Kronberg, PhD, MEG Physics

Keeran Maharajh, PhD, MEG Physics

The magnetoencephalography (MEG) facility is dedicated to research developing new electrophysiological metrics for the assessment of brain function with an emphasis on major mental disorders such as schizophrenia, bipolar disorder and autism. These strategies emphasize the high temporal resolution of MEG, which has millisecond or better timing precision. This directly contrasts MEG with the other technology available at the Brain Imaging Center, fMRI, which has excellent spatial resolution but generally poor temporal resolution. We also combine MEG with MRI information, overlaying the MEG functional results onto anatomical MRI scan data (termed magnetic source imaging: MSI). Recent efforts also include combining the strengths of MEG and fMRI to leverage the high temporal resolution of MEG combined with the high spatial resolution of fMRI.

The MEG Laboratory operates a 248 channel first-order gradiometer system and has the capacity to record up to 64 additional channels of EEG, EKG, EOG or other electrophysiological signals. Stimuli can be delivered in auditory, visual and somatosensory modalities and subject responses may be recorded in a variety of ways. An MEG compatible limbus-tracker is also available for eye-tracking experiments.

The MEG facility, like the MRI scanner, is available as a fee for service. Basic service includes preparatory time and scan time and is billed on a per patient per hour schedule, similar to the 3T MRI. Laboratory staff can provide assistance with experimental design and/or data analysis for an additional fee. MEG physics expertise is available within the laboratory to assist investigators with study design and analysis needs.

The MEG system is also used in the pre-surgical evaluation of epilepsy patients, where we help localize sources of abnormal activity as well as brain regions involved in perception, speech and motor control. These recordings assist a team of neurologists, surgeons and psychologists in planning surgical intervention in cases of medically intractable epilepsy. Follow the Clinical MEG link to the right for information on patient referral.