Skip to main content
Sign In

Mark L. Laudenslager, PhD


Contact Info:
Email:Dr. Laudenslager​

Clinical/Research Interests:

Dr. Laudenslager is interested in the physiological response to stress and developmental psychobiology.​
University of North Carolina  BA  1969

University of California-Santa Barbara  PhD  1975​​​

Member, NIH Special Emphasis Panel [BBBP-2 1998-2001; BBBP6 2005; ZPRG1 F12A-H 2005;  ZRR1 CM-801(6/07); ZAA1 BB(02) P (6/08); ZAA1DD(02) (2009); ZAA1DD(02) (2009); ZRG1 F12B-S (20) (2009)]

Member NIH Study Section (MESH, 2001-2004)

Editorial Board, Brain Behavior and Immunity, 1993-2002, 2004-2008

Secretary, Psychoneuroimmunology Research Society, 2001-2004

Selected Peer-Reviewed Publications (since 2014):

"Anatomy of an Illness": control from a caregiver's perspective. Laudenslager ML. Brain, behavior, and immunity. 2014; 36:1-8. NIHMSID: NIHMS523460
PMID: 24012646  PMCID: PMC3947217

Effect of holding on co-regulation in preterm infants: a randomized controlled trial. Neu M, Hazel NA, Robinson J, Schmiege SJ, Laudenslager M. Early human development. 2014; 90(3):141-7. NIHMSID: NIHMS556923
PMID: 24480604 PMCID: PMC3989889

Anxiety, depression, stress, and cortisol levels in mothers of children undergoing maintenance therapy for childhood acute lymphoblastic leukemia. Neu M, Matthews E, King NA, Cook PF, Laudenslager ML. Journal of pediatric oncology nursing: official journal of the Association of Pediatric Oncology Nurses. 2014; 31(2):104-13. NIHMSID: NIHMS668335 PMID: 24608702 PMCID: PMC4353492

Decreased mental health care utilization following a psychosocial intervention in caregivers of hematopoietic stem cell transplant patients. Ouseph R, Croy C, Natvig C, Simoneau T, Laudenslager ML. Mental illness. 2014; 6(1):5120.PMID: 25478136 PMCID: PMC4253397

Self-compassion training modulates alpha-amylase, heart rate variability, and subjective responses to social evaluative threat in women. Arch JJ, Brown KW, Dean DJ, Landy LN, Brown KD, Laudenslager ML. Psychoneuroendocrinology. 2014; 42:49-58. NIHMSID: NIHMS562220
PMID: 24636501 PMCID: PMC3985278

Chemical processing and shampooing impact cortisol measured in human hair. Hoffman MC, Karban LV, Benitez P, Goodteacher A, Laudenslager ML. Clinical and investigative medicine. Medecine clinique et experimentale. 2014; 37(4):E252-7. NIHMSID: NIHMS669867 PMID: 25090265 PMCID: PMC4370348

Benefits of massage therapy for infants with symptoms of gastroesophageal reflux disease. Neu M, Pan Z, Workman R, Marcheggiani-Howard C, Furuta G, Laudenslager ML. Biological research for nursing. 2014; 16(4):387-97. PMID: 24379449

Multiple latent viruses reactivate in astronauts during Space Shuttle missions. Mehta SK, Laudenslager ML, Stowe RP, Crucian BE, Sams CF, Pierson DL. Brain, behavior, and immunity. 2014; 41:210-7.
PMID: 24886968

Distress among caregivers of phase I trial participants: a cross-sectional study. Kessler ER, Moss A, Eckhardt SG, Laudenslager ML, Kilbourn K, Mauss IB, Bowles DW, Hecker S, Fairclough DL, Kutner JS. Supportive care in cancer: official journal of the Multinational Association of Supportive Care in Cancer. 2014; 22(12):3331-40. NIHMSID: NIHMS668337 PMID: 25120010 PMCID: PMC4356007

Sex, Diet, and the Social Environment: Factors Influencing Hair Cortisol Concentration in Free-Ranging Black Bears (Ursus americanus). Lafferty DJ, Laudenslager ML, Mowat G, Heard D, Belant JL. PloS one. 2015; 10(11):e0141489.
PMID: 26529405 PMCID: PMC4631324

Toward standardization of hair cortisol measurement: results of the first international interlaboratory round robin. Russell E, Kirschbaum C, Laudenslager ML, Stalder T, de Rijke Y, van Rossum EF, Van Uum S, Koren G. Therapeutic drug monitoring. 2015; 37(1):71-5.
PMID: 25387254

Hair Cortisol Analysis: A Promising Biomarker of HPA Activation in Older Adults. Wright KD, Hickman R, Laudenslager ML. The Gerontologist. 2015; 55 Suppl 1:S140-5.
PMID: 26055775 PMCID: PMC4566915

Assessing Systemic Stress in Otolaryngology: Methodology and Feasibility of Hair and Salivary Cortisol Testing.
Genther DJ, Laudenslager ML, Sung YK, Blake CR, Chen DS, Lin FR. Journal of nature and science. 2015; 1(8). NIHMSID: NIHMS725599
PMID: 26436139 PMCID: PMC4592142

A randomized control trial of a psychosocial intervention for caregivers of allogeneic hematopoietic stem cell transplant patients: effects on distress. Laudenslager ML, Simoneau TL, Kilbourn K, Natvig C, Philips S, Spradley J, Benitez P, McSweeney P, Mikulich-Gilbertson SK. Bone marrow transplantation. 2015; 50(8):1110-8. NIHMSID: NIHMS674186 PMID: 25961767 PMCID: PMC4527944

Cardiovascular responses to an acute psychological stressor are associated with the cortisol awakening response in individuals with chronic neck pain. Shahidi B, Sannes T, Laudenslager M, Maluf KS. Physiology & behavior. 2015; 150:93-8. NIHMSID: NIHMS668557
PMID: 25662023 PMCID: PMC4529395

Sleep Moderates and Mediates the Relationship Between Acculturation and Depressive Symptoms in Pregnant Mexican-American Women. D'Anna-Hernandez KL, Garcia E, Coussons-Read M, Laudenslager ML, Ross RG. Maternal and child health journal. 2016; 20(2):422-33. NIHMSID: NIHMS749097
PMID: 26728897 PMCID: PMC4884012

Intraindividual Cortisol Variability and Psychological Functioning in Caregivers of Hematopoietic Stem Cell Transplant Patients. Sannes TS, Mikulich-Gilbertson SK, Natvig CL, Laudenslager ML. Psychosomatic medicine. 2016; 78(2):242-7. NIHMSID: NIHMS725182
PMID: 26569536 PMCID: PMC4738013

Measures of Maternal Stress and Mood in Relation to Preterm Birth. Hoffman MC, Mazzoni SE, Wagner BD, Laudenslager ML, Ross RG. Obstetrics and gynecology. 2016; 127(3):545-52. NIHMSID: NIHMS748388
PMID: 26855101 PMCID: PMC4764470

An Institutional Postdoctoral Research Training Program: Increasing Productivity of Postdoctoral Trainees.
Ross RG, Greco-Sanders L, Laudenslager M. Academic psychiatry: the journal of the American Association of Directors of Psychiatric Residency Training and the Association for Academic Psychiatry. 2016; 40(2):207-12. NIHMSID: NIHMS681238 PMID: 25876090 PMCID: PMC4607540

A randomized controlled pilot study of inflammatory gene expression in response to a stress management intervention for stem cell transplant caregivers. Laudenslager ML, Simoneau TL, Philips S, Benitez P, Natvig C, Cole S. Journal of behavioral medicine. 2016; 39(2):346-54. PMID: 26733011

A case of persistent skin rash and rhinitis with immune system dysregulation onboard the International Space Station. Crucian B, Johnston S, Mehta S, Stowe R, Uchakin P, Quiriarte H, Pierson D, Laudenslager ML, Sams C. The journal of allergy and clinical immunology. In practice. 2016; 4(4):759-762.e8.
PMID: 27036643

Hair cortisol concentration and glycated hemoglobin in African American adults. Lehrer HM, Dubois SK, Maslowsky J, Laudenslager ML, Steinhardt MA. Psychoneuroendocrinology. 2016; 72:212-8.
PMID: 27500952

Caregiver Sleep and Patient Neutrophil Engraftment in Allogeneic Hematopoietic Stem Cell Transplant: A Secondary Analysis. Sannes TS, Mikulich-Gilbertson SK, Natvig CL, Brewer BW, Simoneau TL, Laudenslager ML. Cancer nursing. 2016; NIHMSID: NIHMS820645 
PMID: 27922914 PMCID: PMC5459682

Anxiety and physiological responses to the Trier Social Stress Test for Children in adolescents with cyclic vomiting syndrome. Tarbell SE, Millar A, Laudenslager M, Palmer C, Fortunato JE. Autonomic neuroscience: basic & clinical. 2017; 202:79-85. NIHMSID: NIHMS812017
PMID: 27554769 PMCID: PMC5203938

Cortisol during human fetal life: Characterization of a method for processing small quantities of newborn hair from 26 to 42 weeks gestation. Hoffman MC, D'Anna-Hernandez K, Benitez P, Ross RG, Laudenslager ML. Developmental psychobiology. 2017; 59(1):123-127.
PMID: 27255609

Blunted HPA axis activity prior to suicide attempt and increased inflammation in attempters. Melhem NM, Munroe S, Marsland A, Gray K, Brent D, Porta G, Douaihy A, Laudenslager ML, DePietro F, Diler R, Driscoll H, Gopalan P. Psychoneuroendocrinology. 2017; 77:284-294. NIHMSID: NIHMS842468
PMID: 28135675 PMCID: PMC5336407

Characterizing Sleep in Adolescents and Adults with Autism Spectrum Disorders. Goldman SE, Alder ML, Burgess HJ, Corbett BA, Hundley R, Wofford D, Fawkes DB, Wang L, Laudenslager ML, Malow BA. Journal of autism and developmental disorders. 2017; 47(6):1682-1695. NIHMSID: NIHMS859522
PMID: 28286917 PMCID: PMC5433911

An evidence-based stress management intervention for allogeneic hematopoietic stem cell transplant caregivers: development, feasibility and acceptability. Simoneau TL, Kilbourn K, Spradley J, Laudenslager ML. Supportive care in cancer: official journal of the Multinational Association of Supportive Care in Cancer. 2017; 25(8):2515-2523.
PMID: 28283805

Latent virus reactivation in astronauts on the international space station. Mehta, S.K., Laudenslager, M.L., Stowe, R.P., Crucian, B.E., Fieveson, A.H., Sams, C.F., Pierson, D.L. Nature Microgravity, 2017; 3 (11). doi:10.1038/s41526-017-0015-y 

Development of a Web-Based Intervention for Addressing Distress in Caregivers of Patients Receiving Stem Cell Transplants: Formative Evaluation With Qualitative Interviews and Focus Group. Pensak NA, Joshi T, Simoneau T, Kilbourn K, Carr A, Kutner J, Laudenslager ML. JMIR research protocols. 2017; 6(6):e120. PubMed PMID: 28642213PMCID: PMC5500777.

Research programs

#R01 AA013973 Early experience and low 5-HT markers in alcohol abuse , $2,253,923 Total direct costs (five years)

The major goals of this project are to elucidate the relationship between the quality of early maternal care and the polymorphism in the serotonin transporter protein and adolescent impulsive and aggressive behavior and voluntary alcohol consumption.


#R01 AA013973 ARRA: Early experience and low 5-HT markers in alcohol abuse Supplement, $133,366 Total direct costs (one year)


#1R01CA126971 Psychoeducation for BMT Caregivers: Biobehavioral Markers and Outcome $2,662,249 Total direct costs (Five years)

This is a randomized control trial of a psychoeducation with stress management intervention focused only on caregivers of blood or marrow transplant recipients.  Outcome variables include psychosocial, neuroendocrine, immune, and sleep markers.


Collaborative work with University of California, Los Angeles (Kek Khee Loo, PI, K award), $36,103


Developmental Psychobiology Endowment Fund Grant #383, $9,955


Standing contracts from the University of Texas Southwestern Medical Center at Dallas (Uma Rao PI)

  • GMO-700824 $75,000
  • GMO-101006 $50,000
  • GMO-101007 $75,000


Standing contract from the University of California, Los Angeles (Lynn Fairbanks PI), PO#2000PKN004, $21,207


Standing contracts from the University of Medicine and Dentistry of New Jersey (Michael Lewis, PI)

  • PO #386618    $13,900
  • PO #430309    $ 1,200


Training Programs

“Development of maladaptive behavior”
Principle Investigator/Director: Randal Ross, M.D.
Scientific Director: Mark L. Laudenslager, Ph.D.
Agency: NIMH
Type: 2T32MH015442
Period: 7/1/06-6/30/11
(This is long standing postdoctoral training program in developmental psychobiology.)


Training Medical Students to Become Research Child Psychiatrists”
Principle investigator/Director: Randal Ross, MD
Scientific Director: Mark L. Laudenslager, Ph.D.
Agency: NIMH
Type: R25
Period: 9/1/07 – 8/31/12
(This is a training program aimed at medical students to provide them with specific research and learning experiences relevant to the Medical Scholars Program.)


Research programs recently completed:

"Couples and cancer: Building partner efficacy in caring.”
Principle Investigator William Collinge, Ph.D.
Subcontract PI: Mark L. Laudenslager, Ph.D.
Agency: National Cancer Institute
Type: Phase 2 SBIR CA10360601
Period: 9/01/07 – 8/31/09
(Development of a video instructional tape for a massage intervention for cancer patients by their caregivers.)


“A Telephone Intervention for Caregivers of Hospice Patients”
Principle investigator: Kristin Kilbourn, Ph.D.
Co-Investigator: Mark L. Laudenslager, Ph.D.
Agency: American Cancer Society (Pilot and exploratory projects)
Period: 06/01/07 – 05/31/09
(Telephone counseling intervention to improve psychosocial functioning and quality of life in caregivers of cancer patients in home-based hospice care.)


“Attentional dysfunction in fragile X syndrome”
Principle Investigator: Kenneth MacLean, Ph.D.
Co-Investigator: Mark L. Laudenslager
Agency: NICHD
Type: 1RO1 047029
Period: 8-1-03-7-31-08
(This project uses a mouse model of fragile X syndrome to investigate how sensory abnormalities, HPA axis dysregulation and executive function deficits contribute to the poor attention seen in this disorder.)


“Colorado Program in Aging and Cancer”
Co Principle Investigators TE Byers, MD and RS Schwartz, MD
Agency: NCI
Type: P20 CA10368
Sub project Principal Investigator: Mark L. Laudenslager, Ph.D.
“The caregiving experience: Burden stress, and hormones in older caregivers of cancer patients”
 (Caregiving burden in caregivers of cancer patients as it relates to salivary cortisol and DHEA).