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Thomas J. Crowley, MD Professor 

       Thomas J. Crowley, MD

Recent Publications


Thomas J. Crowley, MD

Professor Emeritus



Positions and Employment


1966-1968 U.S. Air Force, Holloman AFB, New Mexico. Laboratory research in primate neurophysiology, concerned with effects of biogenic amine injection and depletion on circadian rhythms of sleep and wakefulness
1968-1969 Instructor, Department of Psychiatry, University of Colorado School of Medicine
1968-1974    Psychiatric Hospital Ward Chief, University of Colorado School of Medicine
1969-1974  Assistant Professor, Department of Psychiatry, University of Colorado School of Medicine 
1972-1974    Associate Director of Psychiatric Hospital, University of Colorado School of Medicine 
1974-1979  Associate Professor, Department of Psychiatry, University of Colorado School of Medicine
1974      Acting Director and Director of Psychiatric Hospital
1976-1979  NIDA-NIAAA Career Teacher in Alcohol and Drug Abuse 
1979-1999     Executive Director, Addiction Research and Treatment Service
1980-Present Professor, Department of Psychiatry, University of Colorado School of Medicine
1999-Present Director, Division of Substance Dependence, University of Colorado School of Medicine 


Other Experience and Professional Memberships






1971 Diplomate in Psychiatry, American Board of Psychiatry and Neurology
1971-1989 Medical Center Representative, Colorado State Advisory Council of Alcohol and Drug Abuse
1976-1979 Career Teacher in Alcohol and Drug Abuse (NIDA/NIAAA)
1977        Chairman, Colorado State Advisory Council of Alcohol and Drug Abuse
1977   Fellow, American Psychiatric Association
1977-1979 Vice President, Association for Medical Education and Research in Substance Abuse
1977-1980  Associate Editor, Waking and Sleeping
1979-1981  President, Association for Medical Education and Research in Substance Abuse
1979-1983 Member, Psychosocial Internal Review Group (Study Section) of NIAAA
1984 Member, Ad Hoc Advisory Committee for Revision of Substance Use Disorders Category in DSM III, APA
1985-1986  Editorial Board Member, Alcohol and Drug Research
1985-1989      Member, National Advisory Council on Alcohol Abuse and Alcoholism of the U.S. Alcohol, Drug Abuse, and Mental Health Administration
1988-1994      Member, Board of Directors of College on Problems of Drug Dependence
1989-1994 Member, Psychoactive Substance Use Disorders Work Group for Prep of DSM IV, APA
1990-2000 Editorial Board Member, The American Journal on Addictions
1991  President-Elect, College on Problems of Drug Dependence
1992-1993 President, College on Problems of Drug Dependence
1994-1995 Chairman, Board of Scientific Counselors, NIDA Addiction Research Center
1994-1998      Member, Board of Scientific Counselors, NIDA Addiction Research Center
1995-2003 Member, WHO Expert Advisory Panel on Drug Dependence
1996-Present Editorial Board Member, Drug and Alcohol Dependence
1997 Consultant to Dutch Govt. on Trial of Heroin for Treating Heroin Addicts
1997 Institute of Medicine of the US Natl. Academy of Science
1998   Member, Inst. of Medicine Committee for Community Drug Abuse Treatment Report
1999  Member, Inst. of Medicine Advisory Panel for Medical Marijuana Report
2002-Present  Faculty Fellow, Institute for Behavioral Genetics, Boulder, CO
2004-Present Editorial Board Member, Alcoholism: Clinical and Experimental Research
2007-2013     Member, Substance Related Disorders Work Group for Preparation of DSM V, APA
2008-2011 Member, National Institute on Drug Abuse Advisory Council 


U.S. Patent 5,490,501; February 13, 1996. Avalanche Victim’s Air-from-Snow Breathing Device




1992-1999  America’s Best Doctors Database
2000-2005 NIDA, MERIT Award
2005  Marian W. Fischman Award, Dept of Psychiatry, Columbia University



Psychiatry 8001, “The Big Six Substance Problems in Primary Care Medicine”.  Crowley supervises this 2-4 week full-time elective for 4th year medical students (about 4-6 per year).  Students visit treatment programs operated by the Division, have extensive tutorial sessions with clinicians in the programs, see patients, participate in case conferences, etc. 

Introduction to Substance Dependence.  Crowley provides two lectures to the 2nd year medical class, including a live interview with a patient in treatment in the Division’s adolescent service, usually with diagnoses of dependence on several substances plus conduct disorder. 

Substance Dependence Treatment.  Crowley organizes, and gives several lectures in, the department’s 10-hour lecture series for residents on the treatment of substance dependence.  Several other members of the Division faculty also lecture in this very well-received series. 

Lyon-Voorhees Endowed Lecture. Crowley organizes this annual endowed lecture to the department.  Many leading substance-dependence researchers have responded to his invitations to lecture.  The 2008 lecturer was Dr. Tom McLellan, now Deputy “Drug Czar” in the White House.  The 2009 lecturer was Dr. Howard Edenburg, Director of NIAAA’s Collaborative Study on the Genetics of Alcoholism.  The 2010 lecturer was Dr. George Koob of the Scripps Institute. 

Supervision of Junior Faculty and Post-Doctoral Fellows.  Over the years Crowley has been primary mentor to Drs. Riggs, Hopfer, and Sakai as they worked on their NIDA K-awards.  He was a secondary mentor to Dr. Jody Tanabe, a radiologist with a NIDA K-award.  He recently provided post-doctoral supervision to Dr. Heather Gelhorn.  



Although he is a licensed physician, and although his clinical research of course involves a doctor-patient relationship with each subject, Crowley has not directly treated patients for some years.  This is because his research and administrative duties seriously interfere with the obligations of conducting treatment.  However, Crowley does provide clinical consultation and supervision to the treatment staff of the Division’s adolescent treatment programs.



Current Research Support 

2P60 DA 011015-12 (Hewitt)         08/01/1997-02/28/2014


Center on Antisocial Drug Dependence: The Genetics of HIV Risk Behaviors- Crowley, Co-Director

      Core A: Administrative, Educational, and Ethics Core- Crowley, Co-PI,

      Comp. 3: A Neurogenetic Basis for Risky Hiv-Related Decisions- Crowley, PI,

Center representing the University of Colorado’s Institute for Behavioral Genetics, Division of Substance Dependence and Molecular, Cellular, and Developmental Biology.  This center conducts research in antisocial drug dependence, human behavioral genetics and HIV Risk Behaviors.


5R01 DA009842-15 (Crowley)           09/05/2006-04/30/2011                       (MERIT Award in yrs 6-10)   


Substance Dependent Adolescents: Imaging Risk-Taking

The objective of this research is to better understand whether substances diminish the capacity to inhibit behavior by altering brain processing of risky decisions, or do pre-existing, anatomically-based variations of brain processing produce risk-taking propensities, or both.


1R01 DA027748-01 (Tanabe)                09/01/2009-08/31/2014          


Neural Correlates of Avoidance Learning in Substance Abuse

This project, which is based on a negative reinforcement model of drug addiction, will investigate neural correlates of negative reinforcement learning and its relationship to negative affective states in substance dependence.



5 T32 AA 007464-33 (Hoffman)         07/1/2007-06/30/2012 Preceptor


NIAAA Institutional Postdoctoral Training Grant: Behavioral Pharmacogenetics of Drug and Alcohol Abuse

The major goal of this project is to produce well-trained independent researchers in the area of alcohol effects, alcoholism, and drug abuse.