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Recent Publications

Choudhary R, Baturin D, Fosmire S, Freed B, Porter CC. Knockdown of HPRT for selection of genetically modified human hematopoietic progenitor cells. PLoS One, 2013, 8(3):e59594. PMID: 23555045.

Gore L, DeGregori J, Porter CC. Targeting developmental pathways in children with cancer: what price success? The Lancet Oncology, 2013, 14(2):e70-8. PMID: 23369685.

Casas-Selves M, Kim J, Zhang Y, Helfrich BA, Gao D, Porter CC, Bunn PA, Chan DC, Tan AC, DeGregori J. Tankyrase and the canonical Wnt pathway protect lung cancer cells from EGFR inhibition. Cancer Research, 2012, 72(16):4154-64. PMID: 22738915.

Sullivan KD, Padilla-Just N, Henry RE, Porter CC, Kim J, Tentler JJ, Eckhardt SG, Tan AC, DeGregori J, Espinosa JM. ATM and MET kinases are synthetic lethal with nongenotoxic activation of p53. Nat Chem Biol, 2012, 8(7):646-54. PMID: 22660439.

Porter CC, Kim J, Fosmire S, Gearheart CM, van Linden A, Gao D, Tan AC, DeGregori J. Integrated genomic analyses identify WEE1 as a critical mediator of cell fate and novel therapeutic target in acute myeloid leukemia. Leukemia, 2012, 26(6):1266-76. PMID: 22289989.

Porter CC, Baturin DA, Choudhary R, DeGregori J. The relative fitness of hematopoietic progenitor cells influences leukemia progression. Leukemia, 2011, 25(5); 891-5. PMID: 21331070.

Marusyk A, Porter CC, ZaberezhnyyV, DeGregori J. Irradiation selects for p53 mutation in hematopoietic progenitors. PLoS Biology, 2010; 8(3):e1000324. PMID: 20208998.

Schlegel J, Redzic JS, Porter CC, Yurchenko V, Bukrinsky M, Armstrong GS, Zhang F, Isern NG, DeGregori J, Hodges R, and Eisenmesser EZ. Solution characterization of the extracellular region of CD147 and its interaction with its enzyme ligand cyclophilin-A. Journal of Molecular Biology, 2009; 391(3);518-35. PMID: 19500591.

Porter CC, DeGregori J. Interfering RNA-mediated purine analog resistance for in vitro and in vivo cell selection. Blood 2008; 112(12):4466-74. PMID: 18587011.

Bilousova G, Marusyk A, Porter CC, Cardiff RD, DeGregori J. Impaired DNA replication within progenitor cell pools promotes leukemogenesis. PLoS Biol 2005; 3(12): e401. PMID: 16277552.