Pediatrics at CU School of Medicine is among the best in the nation! World-class pediatric residency program and research facilities. Department of Pediatrics, University of Colorado School of Medicine, Children's Hospital Colorado

  Neff Lab Meeting, Mondays at 9:30AM

                              Journal Club, Thursdays at 12PM

---

 Weekly Journal Club

Each week, a recently published paper is reviewed among the Neff lab and collaborating research teams.  Guests are welcome to join.  Please see the links below to view upcoming and previously reviewed papers. 

December

• Week of December 6th, 2012:  A critical role for Mnt in Myc-driven T-cell proliferation and oncogenesis.
• Week of December 11th, 2012:  Dnmt3a silences hematopoietic stem cell self-renewal. Dnmt3a is essential for hematopoietic stem cell differentiation.

November

• Week of November 5th, 2012:  Prdm3 and Prdm16 are H3K9me1 methyltransferases required for mammalian heterochromatin integrity.

• Week of November 12th, 2012:  Mutation of A677 in histone methyltransferase EZH2 inhuman B-cell lymphoma promotes hypertrimethylationof histone H3 on lysine 27 (H3K27)

• Week of November 26th, 2012:  No journal club due to the holiday.

October

• Week of October 1st, 2012:  ASXL1 Mutations Promote Myeloid Transformation through Loss of PRC2-Mediated Gene Repression
  

• Week of October 8th, 2012:  Chromatin signature discovery via histone modification profile alignments

• Week of October 15th, 2012: EZH2 inhibition as a therapeutic strategy for lymphoma with EZH2-activating mutations

• Week of October 22nd, 2012:  Relative Mitochondrial Priming of Myeloblasts and Normal HSCs Determines Chemotherapeutic Success in AML

• Week of October 29th, 2012:  Lab meeting cancelled due to Molecular Biology retreat.

September

• Week of September 24th, 2012:  Asymmetrically Modified Nucleosomes

​